Maurizio Cardelli, Francesca Marchegiani, Pierpaolo Stripoli, Francesco Piacenza, Rina Recchioni, Mirko Di Rosa, Robertina Giacconi, Marco Malavolta, Roberta Galeazzi, Beatrice Arosio, Fiammetta Cafarelli, Francesco Spannella, Antonio Cherubini, Fabrizia Lattanzio, Fabiola Olivieri
The management of geriatric cardiovascular disease (CVD) patients with multimorbidity remains challenging and could potentially be improved by integrating clinical data with innovative prognostic biomarkers. In this context, the analysis of circulating analytes, including cell-free DNA (cfDNA), appears particularly promising. Here, we investigated circulating cfDNA (measured through the quantification of 247bp and and 115bp Alu genomic fragments) in a cohort of 244 geriatric CVD patients with multimorbidity hospitalised for acute CVD or non-CVD events...
April 9, 2024: Mechanisms of Ageing and Development