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Neuroendocrinology

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https://www.readbyqxmd.com/read/28416458/on-the-origins-of-sex-based-differences-in-respiratory-disorders-lessons-and-hypotheses-from-stress-neuroendocrinology-in-developing-rats
#1
REVIEW
Jean-Philippe Rousseau, Luana Tenorio-Lopes, Cécile Baldy, Tara Adele Janes, Stéphanie Fournier, Richard Kinkead
The environment plays a critical role in shaping development and function of the brain. Stress, especially when experienced early in life, can interfere with these processes. In the context of respiratory control, perinatal stress can therefore alter the ability to achieve the "fine-tuning" necessary for proper detection of chemosensory stimuli and production of an adequate motor (respiratory) command. Depending on the timing, intensity, and duration, the detrimental consequences of perinatal exposure to adverse conditions on the respiratory network become manifest at various life stages and can persist into adulthood...
April 14, 2017: Respiratory Physiology & Neurobiology
https://www.readbyqxmd.com/read/28389053/non-functioning-pituitary-adenoma-underwent-surgery-a-multicenter-retrospective-study-over-the-last-four-decades-1977-2015
#2
Pedro Iglesias, Karina Arcano, Vanessa Triviño, Paula García-Sancho, Juan José Díez, Fernando Cordido, Carles Villabona
OBJECTIVE: To assess clinical features, diagnostic procedures, therapies and outcomes in patients with clinically non-functioning pituitary adenomas (NFPAs) surgically treated over the last four decades. DESIGN AND METHODS: A multicenter retrospective study in NFPA patients periodically followed up in specialized neuroendocrinology units who underwent surgery in the period 1977-2015 was performed. RESULTS: A total of 131 patients were studied [66 women (50...
April 4, 2017: European Journal of Internal Medicine
https://www.readbyqxmd.com/read/28377689/editorial-chemicals-in-the-environment-and-brain-development-importance-of-neuroendocrinological-approaches
#3
EDITORIAL
Fumihiko Maekawa, Kazuaki Nakamura, Shoji F Nakayama
No abstract text is available yet for this article.
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28274736/zebrafish-an-emerging-model-system-to-explore-thyroid-hormone-transporters
#4
David Zada, Einat Blitz, Lior Appelbaum
Thyroid hormones (THs) regulate a variety of fundamental physiological processes, including the development and maintenance of the brain. For decades, it was thought that THs enter the cells by passive diffusion. However, it is now clear that TH transport across the cell membrane requires specific transporter proteins that facilitate the uptake and efflux of THs. Several thyroid hormone transmembrane transporters (THTTs) have been identified, including monocarboxylate transporter 8 (MCT8), MCT10, and organic anion transporting polypeptide 1C1 (OATP1C1)...
March 5, 2017: Molecular and Cellular Endocrinology
https://www.readbyqxmd.com/read/28265842/jean-camus-and-gustave-roussy-pioneering-french-researchers-on-the-endocrine-functions-of-the-hypothalamus
#5
Inés Castro-Dufourny, Rodrigo Carrasco, Ruth Prieto, José M Pascual
At the beginning of the twentieth century, the hypothalamus was known merely as an anatomical region of the brain lying beneath the thalamus. An increasing number of clinicopathological reports had shown the association of diabetes insipidus and adiposogenital dystrophy (Babinski-Fröhlich's syndrome), with pituitary tumors involving the infundibulum and tuber cinereum, two structures of the basal hypothalamus. The French physicians Jean Camus (1872-1924) and Gustave Roussy (1874-1948) were the first authors to undertake systematic, controlled observations of the effects of localized injuries to the basal hypothalamus in dogs and cats by pricking the infundibulo-tuberal region (ITR) with a heated needle...
March 6, 2017: Pituitary
https://www.readbyqxmd.com/read/28259721/neuroendocrinology-and-brain-imaging-of-reward-in-eating-disorders-a-possible-key-to-the-treatment-of-anorexia-nervosa-and-bulimia-nervosa
#6
REVIEW
Alessio Maria Monteleone, Giovanni Castellini, Umberto Volpe, Valdo Ricca, Lorenzo Lelli, Palmiero Monteleone, Mario Maj
Anorexia nervosa and bulimia nervosa are severe eating disorders whose etiopathogenesis is still unknown. Clinical features suggest that eating disorders may develop as reward-dependent syndromes, since eating less food is perceived as rewarding in anorexia nervosa while consumption of large amounts of food during binge episodes in bulimia nervosa aims at reducing the patient's negative emotional states. Therefore, brain reward mechanisms have been a major focus of research in the attempt to contribute to the comprehension of the pathophysiology of these disorders...
March 1, 2017: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/28257837/identification-and-distribution-of-products-from-novel-tryptopyrokinin-genes-in-the-locust-locusta-migratoria
#7
Jana Redeker, Marcel Bläser, Susanne Neupert, Reinhard Predel
A recent analysis of the genome of Locusta migratoria indicated the presence of four novel insect neuropeptide genes encoding for multiple tryptopyrokinin peptides (tryptoPKs); hitherto only known from pyrokinin or capa genes. In our study, mature products of tryptoPK genes 1 and 2 were identified by mass spectrometry; precursor sequences assigned to the tryptoPK genes 3 and 4 are likely partial sequences of a single precursor. The expression of tryptoPK genes 1 and 2 is restricted to two cells in the subesophageal ganglion, exhibiting not only a unique neuropeptidome but also a very distinctive axonal projection...
April 22, 2017: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/28252507/neurobiology-of-comorbid-substance-use-disorders-and-psychiatric-disorders-current-state-of-evidence
#8
Yatan Pal Singh Balhara, Pooja Patnaik Kuppili, Rishab Gupta
BACKGROUND: "Dual disorder" or "dual diagnosis" refers to the co-occurrence of substance use disorder and psychiatric disorders. Prospective studies have shown that treatment outcomes, such as symptom levels, hospitalization rates, housing stability, and functional status, are worse among the patients with dual disorders as compared with those who have either of these disorders. OBJECTIVES: The current article is aimed at reviewing the current state of evidence on neurobiology of dual disorders...
January 2017: Journal of Addictions Nursing
https://www.readbyqxmd.com/read/28237271/evidence-based-treatments-for-low-sexual-desire-in-women
#9
REVIEW
Lori A Brotto
Low sexual desire is the most common sexual complaint in women, with multinational studies finding that at least a third of women experience low sexual desire. No single etiology for the development of Female Sexual Interest/Arousal Disorder, the diagnosis laid out by the 5th edition of the Diagnostic and Statistical Manual of Mental Disorders, has been established. There has been considerable interest in pharmacological approaches to improving low desire, and agents targeting a range of neurotransmitters have been examined...
April 2017: Frontiers in Neuroendocrinology
https://www.readbyqxmd.com/read/28216411/a-summary-of-the-proceedings-of-the-thirteenth-international-symposium-on-the-neurobiology-and-neuroendocrinology-of-aging-bregenz-austria-july-17-22-2016
#10
EDITORIAL
Holly M Brown-Borg, Kurt E Borg
A summary of the Thirteenth International Symposium on the Neurobiology and Neuroendocrinology of Aging that was held July 17-22, 2016 in Bregenz, Austria, is presented. Twenty-one of the speakers that presented at the conference submitted review papers covering the topic of their presentation as well as an overview of their respective fields and are included in this special issue. The abstracts from each poster presentation as well as twenty-two of the speaker abstracts are also included at the end of the preface to the special issue...
February 16, 2017: Experimental Gerontology
https://www.readbyqxmd.com/read/28185936/why-goldfish-merits-and-challenges-in-employing-goldfish-as-a-model-organism-in-comparative-endocrinology-research
#11
Ayelén Melisa Blanco, Lakshminarasimhan Sundarrajan, Juan Ignacio Bertucci, Suraj Unniappan
Goldfish has been used as an unconventional model organism to study a number of biological processes. For example, goldfish is a well-characterized and widely used model in comparative endocrinology, especially in neuroendocrinology. Several decades of research has established and validated an array of tools to study hormones in goldfish. The detailed brain atlas of goldfish, together with the stereotaxic apparatus, are invaluable tools for the neuroanatomic localization and central administration of endocrine factors...
February 7, 2017: General and Comparative Endocrinology
https://www.readbyqxmd.com/read/28144217/subtle-scientific-fallacies-undermine-the-validity-of-neuroendocrinological-research-do-not-draw-premature-conclusions-on-the-role-of-female-sex-hormones
#12
Michael P Hengartner
Major scientific flaws such as reporting and publication biases are well documented, even though acknowledgment of their importance appears to be lacking in various psychological and medical fields. Subtle and less obvious biases including selective reviews of the literature and empirically unsupported conclusions and recommendations have received even less attention. Using the literature on the association between transition to menopause, hormones and the onset of depression as a guiding example, I outline how such scientific fallacies undermine the validity of neuroendocrinological research...
2017: Frontiers in Behavioral Neuroscience
https://www.readbyqxmd.com/read/28131534/the-first-sixty-five-craniopharyngioma-operations-in-france
#13
REVIEW
I Castro-Dufourny, R Carrasco, R Prieto, L Barrios, J-M Pascual
Craniopharyngiomas (CPs) are benign epithelial tumors that develop along the hypothalamus-hypophyseal axis and were first described by Jakob Erdheim in 1904. These tumors have represented a challenge for surgeons since the rise of modern neurosurgery. The study of CPs is linked to the development of this surgical discipline in parallel with neuroendocrinology within the French school of neurology, led by Joseph Babinski. For the present study, all CP cases published in the French scientific literature before the development of modern neuroradiology were gathered, and 65 cases that underwent surgical procedures between 1921 and 1973 were selected...
January 25, 2017: Revue Neurologique
https://www.readbyqxmd.com/read/28094875/neuroendocrinology-of-mast-cells-challenges-and-controversies
#14
REVIEW
Theoharis C Theoharides
Mast cells (MC) are hemotopoietically derived tissue immune cells that are ubiquitous in the body, including neuroendocrine organs such as the hypothalamus, pineal, pituitary, ovaries, pancreas and uterus where their action is not well understood. Mast cells have historically been associated with allergies because of their rich content of histamine and tryptase, but more recently with regulation of immunity and inflammation due to their synthesis and release of numerous cytokines and chemokines. Mast cells are located perivascularly and express numerous receptors for diverse ligands such as allergens, pathogens, neurotransmitters, neuropeptides and hormones including acetylcholine, calcitonin gene-related peptide (CGRP), corticosteroids, corticotropin-releasing hormone (CRH), β-endorphin, epinephrine, 17β-oestradiol, gonadotrophins, hemokinin-A (HKA), leptin, melatonin, neurotensin (NT), parathyroid hormone (PTH), substance P (SP) and vasoactive intestinal peptide (VIP)...
January 17, 2017: Experimental Dermatology
https://www.readbyqxmd.com/read/28074555/paediatric-stress-from-neuroendocrinology-to-contemporary-disorders
#15
REVIEW
Stavroula Stavrou, Nicolas C Nicolaides, Elena Critselis, Christina Darviri, Evangelia Charmandari, George P Chrousos
BACKGROUND: Stress is defined as a state of threatened or perceived as threatened homeostasis. A broad spectrum of extrinsic or intrinsic, real or perceived stressful stimuli, called 'stressors', activates a highly conserved system, the 'stress system', which adjusts homeostasis through central and peripheral neuroendocrine responses. Inadequate, excessive or prolonged adaptive responses to stress may underlie the pathogenesis of several disease states prevalent in modern societies. The development and severity of these conditions primarily depend on the genetic vulnerability of the individual, the exposure to adverse environmental factors and the timing of the stressful event(s), given that prenatal life, infancy, childhood and adolescence are critical periods characterized by increased vulnerability to stressors...
January 11, 2017: European Journal of Clinical Investigation
https://www.readbyqxmd.com/read/28059155/neuroendocrinology-in-2016-neuroendocrine-control-of-metabolism-and-reproduction
#16
Manuel Tena-Sempere
No abstract text is available yet for this article.
February 2017: Nature Reviews. Endocrinology
https://www.readbyqxmd.com/read/28042663/all-our-sons-the-developmental-neurobiology-and-neuroendocrinology-of-boys-at-risk
#17
Allan N Schore
Why are boys at risk? To address this question, I use the perspective of regulation theory to offer a model of the deeper psychoneurobiological mechanisms that underlie the vulnerability of the developing male. The central thesis of this work dictates that significant gender differences are seen between male and female social and emotional functions in the earliest stages of development, and that these result from not only differences in sex hormones and social experiences but also in rates of male and female brain maturation, specifically in the early developing right brain...
January 2017: Infant Mental Health Journal
https://www.readbyqxmd.com/read/28002818/safety-outcomes-and-near-adult-height-gain-of-growth-hormone-treated-children-with-shox-deficiency-data-from-an-observational-study-and-a-clinical-trial
#18
Imane Benabbad, Myriam Rosilio, Christopher J Child, Jean-Claude Carel, Judith L Ross, Cheri L Deal, Stenvert L S Drop, Alan G Zimmermann, Nan Jia, Charmian A Quigley, Werner F Blum
BACKGROUND/AIMS: To assess auxological and safety data for growth hormone (GH)-treated children with SHOX deficiency. METHODS: Data were examined for GH-treated SHOX-deficient children (n = 521) from the observational Genetics and Neuroendocrinology of Short Stature International Study (GeNeSIS). For patients with near-adult height information, GeNeSIS results (n = 90) were compared with a clinical trial (n = 28) of SHOX-deficient patients. Near-adult height was expressed as standard deviation score (SDS) for chronological age, potentially increasing the observed effect of treatment...
2017: Hormone Research in Pædiatrics
https://www.readbyqxmd.com/read/27924858/transcriptomic-characterization-and-curation-of-candidate-neuropeptides-regulating-reproduction-in-the-eyestalk-ganglia-of-the-australian-crayfish-cherax-quadricarinatus
#19
Tuan Viet Nguyen, Scott F Cummins, Abigail Elizur, Tomer Ventura
The Australian redclaw crayfish (Cherax quadricarinatus) has recently received attention as an emerging candidate for sustainable aquaculture production in Australia and worldwide. More importantly, C. quadricarinatus serves as a good model organism for the commercially important group of decapod crustaceans as it is distributed worldwide, easy to maintain in the laboratory and its reproductive cycle has been well documented. In order to better understand the key reproduction and development regulating mechanisms in decapod crustaceans, the molecular toolkit available for model organisms such as C...
December 7, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27900416/-intensive-care-treatment-after-aneurysmal-subarachnoid-hemorrhage
#20
REVIEW
U Jaschinski
Aneurysmal subarachnoid hemorrhage (SAH) is a devastating disease and nearly one third of patients die in the acute phase. Due to the bleeding event, a hyperactive sympathetic nervous system and an uncontrolled inflammatory response have a profound local and systemic impact on other organ functions. Neuroendocrinological disorders and cardiopulmonary morbidity are dominant. Despite a decrease in hospital mortality for high volume centers, a high proportion of survivors suffer from neurological deficits. Knowledge of the pathophysiology of vasospasms in the later stages of the disease has increased...
December 2016: Der Anaesthesist
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