keyword
https://read.qxmd.com/read/38541103/a-chronic-obstructive-pulmonary-disease-self-management-intervention-for-improving-patient-reported-outcomes-in-primary-care-in-greece
#1
JOURNAL ARTICLE
Filothei Tsaousi, Izolde Bouloukaki, Antonios Christodoulakis, Despo Ierodiakonou, Nikos Tzanakis, Ioanna Tsiligianni
Background and Objectives : Self-management programs are essential for increasing COPD patient participation and autonomy in making appropriate decisions about their chronic condition. The present study aimed to assess the impact of COPD self-management interventions on quality of life, functional status, patient education, depression, and anxiety in primary care. Materials and Methods : We conducted a randomized controlled trial recruiting patients with COPD (GOLD A and B) from four primary care centers in Crete, Greece, with one intervention group ( n = 40) receiving self-management educational support and one control group ( n = 80) receiving usual care...
February 23, 2024: Medicina
https://read.qxmd.com/read/38536775/inflammatory-biomarker-based-clinical-practice-in-patients-with-pneumonia-a-systematic-review-of-randomized-controlled-trials
#2
JOURNAL ARTICLE
Dimitrios Dimitropoulos, Michalis Karmpadakis, Themistoklis Paraskevas, Christos Michailides, Maria Lagadinou, Christina Platanaki, Charalampos Pierrakos, Dimitrios Velissaris
UNLABELLED: Objectives: Biomarker-based clinical practice is currently gaining ground and increasingly affects decision making. A variety of biomarkers have been studied through the years and some of them have already an established role in modern medicine, such as procalcitonin (PCT) which has been proposed to reduce antibiotic exposure. We purposed to systematically review all biomarkers examined for guiding the clinical practice in patients with pneumonia. METHODS: A systematic review on PubMed was performed on April 2023 by two independent researchers using the PRISMA guidelines...
March 27, 2024: Romanian Journal of Internal Medicine
https://read.qxmd.com/read/38523907/efficacy-and-safety-of-a-music-therapy-facilitated-pulmonary-telerehabilitation-program-in-copd-patients-the-copdmelody-study-protocol
#3
JOURNAL ARTICLE
Minghui Shi, Lulu Yang, Shiwei Qumu, Jieping Lei, Ke Huang, Ruoxi He, Hongtao Niu, Fen Dong, Siyuan Wang, Jiaze He, Ting Yang
Despite considerable evidence for the benefit in chronic obstructive pulmonary disease (COPD), the implementation of pulmonary rehabilitation (PR) is insufficient. However, music therapy may help address this gap due to its unique benefits. Therefore, we aimed to develop a music-therapy facilitated pulmonary telerehabilitation program based on rhythm-guided walking, singing, and objective telemonitoring. A supervised, parallel-group, single-blinded, randomized controlled clinical trial will be conducted, including 75 patients with COPD anticipated to be randomized in a 1:1:1 ratio into three groups...
2024: Frontiers in Medicine
https://read.qxmd.com/read/38510651/chinese-medicine-phragmites-communis-lu-gen-for-acute-respiratory-tract-infections-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#4
Min Fang, Ling-Yao Kong, Guang-He Ji, Feng-Lan Pu, You-Zhu Su, Yu-Fei Li, Michael Moore, Merlin Willcox, Jeanne Trill, Xiao-Yang Hu, Jian-Ping Liu
Background: Acute respiratory tract infections (ARTIs) are the most common cause of morbidity and mortality worldwide, with most people experiencing at least one episode per year. Current treatment options are mainly symptomatic therapy. Antivirals, antibiotics, and glucocorticoids are of limited benefit for most infections. Traditional Chinese medicine has shown potential benefits in the treatment of ARTIs. Objective: The objective of this study was to determine the efficacy, effectiveness, and safety of Phragmites communis Trin...
2024: Frontiers in Pharmacology
https://read.qxmd.com/read/38509576/a-cluster-randomized-study-to-evaluate-the-effectiveness-and-cost-effectiveness-of-the-assessment-of-burden-of-chronic-conditions-abcc-tool-in-south-tyrolean-primary-care-for-patients-with-copd-asthma-type-2-diabetes-and-heart-failure-the-abcc-south-tyrol-study
#5
JOURNAL ARTICLE
Christian J Wiedermann, Pasqualina Marino, Angelika Mahlknecht, Verena Barbieri, Giuliano Piccoliori, Adolf Engl, Annerika H M Gidding-Slok
BACKGROUND: Chronic diseases, such as chronic obstructive pulmonary disease (COPD), asthma, type 2 diabetes, and heart failure, often coexist and contribute to a significant burden on individuals and health systems. The Assessment of Burden of Chronic Conditions (ABCC) tool, already in routine clinical use in the Netherlands, aims to comprehensively assess and visualize disease burden, stimulate self-management, and encourage shared decision-making. This study aims to validate the German and Italian versions of the ABCC tool and evaluate its effectiveness and cost-effectiveness in the South Tyrolean Primary Care setting...
March 20, 2024: Trials
https://read.qxmd.com/read/38508668/inhaled-versus-systemic-corticosteroids-for-acute-exacerbations-of-copd-a-systematic-review-and-meta-analysis
#6
REVIEW
Efthymia Papadopoulou, Sulaiman Bin Safar, Ali Khalil, Jan Hansel, Ran Wang, Alexandru Corlateanu, Konstantinos Kostikas, Stavros Tryfon, Jørgen Vestbo, Alexander G Mathioudakis
This meta-analysis compares the efficacy and safety of inhaled versus systemic corticosteroids for COPD exacerbations.Following a pre-registered protocol, we appraised eligible randomised controlled trials (RCTs) according to Cochrane methodology, performed random-effects meta-analyses for all outcomes prioritised in the European Respiratory Society COPD core outcome set and rated the certainty of evidence as per Grading of Recommendations Assessment, Development and Evaluation methodology.We included 20 RCTs totalling 2140 participants with moderate or severe exacerbations...
January 31, 2024: European Respiratory Review: An Official Journal of the European Respiratory Society
https://read.qxmd.com/read/38508236/cost-effectiveness-and-cost-utility-study-of-a-psychoeducational-group-intervention-for-people-with-depression-and-physical-comorbidity-in-primary-care
#7
JOURNAL ARTICLE
Antonia Raya-Tena, María Isabel Fernández-San-Martín, Jaume Martín-Royo, Marc Casajuana-Closas, María Francisca Jiménez-Herrera
OBJECTIVE: To evaluate the cost-effectiveness and cost-utility of a psychoeducational group intervention led by primary care (PC) nurses in relation to customary care to prevent the depression and improve quality of life in patients with physical comorbidity. DESIGN: Economic evaluation based on data from randomized, multicenter clinical trial with blind response variables and a one-year follow-up, carried in the context of the PSICODEP study. LOCATION: 27 PC teams from Catalonia...
March 18, 2024: Enfermería clínica (English Edition)
https://read.qxmd.com/read/38504215/integrating-palliative-care-education-in-pulmonary-rehabilitation-a-randomized-controlled-study-protocol
#8
JOURNAL ARTICLE
M Aurora Mendes, Daisy J A Janssen, Alda Marques
BACKGROUND: Palliative care addresses multiple unmet needs of people with chronic obstructive pulmonary disease (COPD) or interstitial lung diseases (ILD) and their family and/or friend caregivers, but it remains highly underused. Pulmonary rehabilitation (PR) may provide a key opportunity to introduce palliative care. We aim to explore the effects of palliative care education as part of PR on knowledge about this field in people with COPD or ILD and their family and/or friend caregivers...
March 20, 2024: BMC Palliative Care
https://read.qxmd.com/read/38503629/efficacy-of-nemiralisib-in-chronic-obstructive-pulmonary-disease-a-systematic-review
#9
REVIEW
Hongkuan Yang, Shuifeng He, Linbao Liang, Junjie Pan
PURPOSE: Chronic obstructive pulmonary disease (COPD) is a major public health concern. Exacerbation of COPD leads to poor health and frequent episodes of increased systemic and airway inflammation. Immunomodulatory drugs have garnered extensive attention because they may reduce the rate of COPD exacerbation. This review aimed to evaluate the efficacy and safety of nemiralisib in COPD patients. METHODS: Medical databases, including the Cochrane Library, EMBASE, and PubMed, were queried from inception to June 2023 to identify randomized controlled trials (RCTs) on the efficacy of nemiralisib in COPD patients...
March 18, 2024: Clinical Therapeutics
https://read.qxmd.com/read/38503464/a-network-meta-analysis-on-the-effects-of-different-exercise-types-on-copd-patients
#10
REVIEW
Chengping Jian, Xiangdong Peng, Yuting Yang, Yanli Xu, Liying Wang, Defang Cai
Objective: This study aimed to compare and rank the effects of aerobic exercise (AE), resistance training (RT), endurance training (ET), and high-intensity interval training (HIIT) in chronic obstructive pulmonary disease (COPD) by network meta-analysis (NMA). Methods: PubMed, Cochrane, Embase, and Web of Science were searched to identify randomized controlled trials investigating the effects of exercise training on COPD. The search period began on the date of database establishment and ended in April 8, 2023...
March 19, 2024: Respiratory Care
https://read.qxmd.com/read/38501382/the-value-of-the-nutritional-indicators-in-predicting-free-flap-failure-from-a-multicentre-database
#11
JOURNAL ARTICLE
Yuan-Hao Yen, Sheng-Dean Luo, Wei-Chih Chen, Chung-Yi Li, Tai-Jan Chiu, Yu-Ming Wang, Shao-Chun Wu, Yao-Hsu Yang, Yung-Hsuan Chen, Ching-Nung Wu
OBJECTIVE: Nutritional and inflammatory statuses have been associated with complications in microvascular-free flaps during head and neck surgeries. This study aimed to evaluate the potential of nutritional indicators in predicting postoperative free flap complications. STUDY DESIGN: We conducted a 20-year retrospective, case-control study within a defined cohort. SETTING: The study involved head and neck cancer patients from the Chang Gung Research Database who underwent simultaneous tumor ablation and free flap wound reconstruction between January 1, 2001, and December 31, 2019...
March 19, 2024: Otolaryngology—Head and Neck Surgery
https://read.qxmd.com/read/38500191/the-improve-trial-study-protocol-for-a-pragmatic-cluster-randomised-controlled-trial-to-assess-the-effectiveness-of-using-lay-health-workers-to-improve-uptake-and-completion-of-pulmonary-rehabilitation-in-patients-with-chronic-obstructive-pulmonary-disease
#12
JOURNAL ARTICLE
Gill Gilworth, Katherine Harris, Toby L Morgan, Salma Ayis, Julia Fox-Rushby, Emma Godfrey, Nicholas S Hopkinson, Simon Lewin, Ka Keat Lim, Arietta Spinou, Stephanie J C Taylor, Patrick White
BACKGROUND: Pulmonary rehabilitation (PR) is a programme of exercise and education and the most effective treatment for the symptoms and disability associated with chronic obstructive pulmonary disease. However, the benefits of PR are limited by poor uptake and completion. This trial will determine whether using trained volunteer lay health workers, called "PR buddies," improves uptake and completion of PR and is cost-effective. This trial protocol outlines the methods for evaluating effectiveness, cost-effectiveness, and acceptability...
March 19, 2024: Trials
https://read.qxmd.com/read/38496359/effects-of-pulmonary-rehabilitation-on-systemic-inflammation-in-chronic-obstructive-pulmonary-disease-a-meta-analysis
#13
REVIEW
Xiaotian Alex Yue, Yilan Sheng, Jianhua Li
Chronic obstructive pulmonary disease (COPD) is marked by both lung-related and systemic symptoms, notably chronic inflammation. Despite pulmonary rehabilitation (PR) being a critical treatment for COPD, its influence on systemic inflammation remains unclear. This meta-analysis was conducted to assess PR's effect on circulating inflammatory markers in COPD patients. We systematically reviewed databases like PubMed, EMBASE, and Web of Science to select randomized controlled trials and observational studies that investigated the impact of PR on systemic inflammation...
2024: American Journal of Clinical and Experimental Immunology
https://read.qxmd.com/read/38495520/internet-of-things-based-management-versus-standard-management-of-home-noninvasive-ventilation-in-copd-patients-with-hypercapnic-chronic-respiratory-failure-a-multicentre-randomized-controlled-non-inferiority-trial
#14
JOURNAL ARTICLE
Weipeng Jiang, Xiaoyan Jin, Chunling Du, Wenchao Gu, Xiwen Gao, Chenjun Zhou, Chunlin Tu, Hongqun Chen, Hong Li, Yao Shen, Yunfeng Zhang, Xiahui Ge, Yingxin Sun, Lei Zhou, Suyun Yu, Kaishun Zhao, Qing Cheng, Xiaodan Zhu, Hongen Liao, Chunxue Bai, Yuanlin Song
BACKGROUND: Effective monitoring and management are crucial during long-term home noninvasive positive pressure ventilation (NPPV) in patients with hypercapnic chronic obstructive pulmonary disease (COPD). This study investigated the benefit of Internet of Things (IOT)-based management of home NPPV. METHODS: This multicenter, prospective, parallel-group, randomized controlled non-inferiority trial enrolled patients requiring long-term home NPPV for hypercapnic COPD...
April 2024: EClinicalMedicine
https://read.qxmd.com/read/38494828/efficacy-of-varenicline-or-bupropion-and-its-association-with-nicotine-metabolite-ratio-among-smokers-with-copd
#15
JOURNAL ARTICLE
Rui Qin, Zhao Liu, An-Qi Cheng, Xin-Mei Zhou, Zheng Su, Zi-Yang Cui, Jin-Xuan Li, Xiao-Wen Wei, Liang Zhao, Kian Fan Chung, Dan Xiao, Chen Wang
BACKGROUND AND OBJECTIVE: Nicotine metabolic ratio (NMR) has been associated with nicotine metabolism and smoking characteristics. However, there are few studies on the potential association between NMR and smoking cessation efficacy in smokers with chronic obstructive pulmonary disease (COPD) in China or elsewhere. METHODS: This study was a stratified block randomized controlled trial for smoking cessation in Chinese smokers with COPD. NMR was used as a stratification factor; slow metabolizers were defined as those with NMR <0...
March 17, 2024: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://read.qxmd.com/read/38483650/systematic-review-and-meta-analysis-of-nutrient-supplements-for-treating-sarcopenia-in-people-with-chronic-obstructive-pulmonary-disease
#16
Wen-Jian Huang, Chih-Yuan Ko
Individuals with chronic obstructive pulmonary disease (COPD) are prone to malnutrition and sarcopenia as a result of nutritional deficiencies and increased energy metabolism. However, the effects of nutrient supplements (NS) on treating sarcopenia in patients with COPD are not well established from systematic evidence. This meta-analysis examined the effect of NS on sarcopenia in patients with COPD. A systematic search of multiple databases was conducted, and 29 randomized controlled trials involving 1625 participants (age, mean [SD] = 67...
March 14, 2024: Aging Clinical and Experimental Research
https://read.qxmd.com/read/38474867/combined-effect-of-early-nutrition-therapy-and-rehabilitation-for-patients-with-chronic-obstructive-pulmonary-disease-exacerbation-a-prospective-randomized-controlled-trial
#17
RANDOMIZED CONTROLLED TRIAL
Yohei Oyama, Hiroomi Tatsumi, Hiroko Takikawa, Natsuko Taniguchi, Yoshiki Masuda
The effectiveness of rehabilitation programs (RP) for chronic obstructive pulmonary disease (COPD) exacerbation remains controversial. However, few studies have investigated the combined effects of exercise and nutritional therapy. This study aimed to determine the effects of combined nutritional therapy on the physical function and nutritional status of patients with COPD exacerbation who underwent early RP. A randomized controlled trial was conducted in patients hospitalized for COPD exacerbations. Patients were assigned to receive a regular diet in addition to RP (control group) or RP and nutrition therapy (intervention group)...
March 5, 2024: Nutrients
https://read.qxmd.com/read/38472401/pressure-support-ventilation-versus-t-piece-as-spontaneous-breathing-trials-for-extubation-of-patients-with-chronic-obstructive-pulmonary-disease-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#18
JOURNAL ARTICLE
Luiza Mendes Fonseca, Pedro Matos da Câmara, Iane Miguel Pereira Lettieri, Caroline Serafim Dagostin, Arthur Oswaldo de Abreu Vianna
BACKGROUND: Weaning patients with COPD from mechanical ventilation (MV) presents a challenge, as literature on this topic is limited. This study compares PSV and T-piece during spontaneous breathing trials (SBT) in this specific population. METHODS: A search of PubMed, EMBASE, and Cochrane in September 2023 yielded four randomized controlled trials (RCTs) encompassing 560 patients. Among these, 287 (51%) used T-piece during SBTs. RESULTS: The PSV group demonstrated a significant improvement in the successful extubation rate compared to the T-piece (risk ratio [RR] 1...
March 12, 2024: Lung
https://read.qxmd.com/read/38467310/systematic-review-of-tailored-dietary-advice-and-dietitian-involvement-in-the-treatment-of-chronic-obstructive-pulmonary-disease-copd
#19
REVIEW
Kylie Bell, Josh Lawson, Erika Penz, Allison Cammer
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a leading public health concern globally. Interdisciplinary pulmonary rehabilitation programs exist and should ideally consider nutritional health impacts since the nutritional status of COPD patients is often compromised. However, little is known about the role of dietary counseling in COPD management. RESEARCH QUESTION: Does providing tailored dietary advice to adult patients with COPD improve outcomes? STUDY DESIGN AND METHODS: We conducted a systematic review...
March 9, 2024: Respiratory Medicine
https://read.qxmd.com/read/38458558/project-epic-empowering-people-to-independence-in-copd-study-protocol-for-a-hybrid-effectiveness-implementation-pilot-randomized-controlled-trial-of-telephonic-geriatrics-palliative-care-nurse-coaching-in-older-adults-with-copd-and-their-family-caregivers
#20
JOURNAL ARTICLE
Jun Y Byun, Rachel Wells, Avery C Bechthold, Jazmine Coffee-Dunning, Margaret Armstrong, Richard Taylor, Lanier O'Hare, Mark T Dransfield, Cynthia J Brown, David E Vance, J Nicholas Odom, Marie Bakitas, Anand S Iyer
BACKGROUND: EPIC (Empowering People to Independence in COPD) is a geriatric-palliative care telephonic, nurse coach intervention informed by Baltes' Theory of Successful Aging and adapted from the ENABLE (Educate, Nurture, Advise, Before Life Ends) intervention. EPIC, focused on improving independence, mobility, well-being, and COPD symptoms, has undergone formative and summative evaluation for adults with COPD. METHODS: The primary study aim is to assess the refined EPIC intervention's feasibility and acceptability via a pilot hybrid effectiveness-implementation randomized control trial in community-dwelling older adults with moderate to severe COPD and their family caregivers...
March 6, 2024: Contemporary Clinical Trials
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