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https://www.readbyqxmd.com/read/28181091/neuro-emotional-technique-effects-on-brain-physiology-in-cancer-patients-with-traumatic-stress-symptoms-preliminary-findings
#1
Daniel A Monti, Anna Tobia, Marie Stoner, Nancy Wintering, Michael Matthews, Xiao-Song He, Gaelle Doucet, Inna Chervoneva, Joseph I Tracy, Andrew B Newberg
PURPOSE: The purpose of this study was to characterize the neurophysiological and clinical effects that may result from the neuro emotional technique (NET) in patients with traumatic stress symptoms associated with a cancer-related event. We hypothesized that self-regulatory processing of traumatic memories would be observable as physiological changes in key brain areas after undergoing the NET intervention and that these changes would be associated with improvement of traumatic stress symptoms...
February 8, 2017: Journal of Cancer Survivorship: Research and Practice
https://www.readbyqxmd.com/read/28174516/anocva-in-r-a-software-to-compare-clusters-between-groups-and-its-application-to-the-study-of-autism-spectrum-disorder
#2
Maciel C Vidal, João R Sato, Joana B Balardin, Daniel Y Takahashi, André Fujita
Understanding how brain activities cluster can help in the diagnosis of neuropsychological disorders. Thus, it is important to be able to identify alterations in the clustering structure of functional brain networks. Here, we provide an R implementation of Analysis of Cluster Variability (ANOCVA), which statistically tests (1) whether a set of brain regions of interest (ROI) are equally clustered between two or more populations and (2) whether the contribution of each ROI to the differences in clustering is significant...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28162639/-395-brainstem-activity-and-connectivity-is-modulated-by-respiratory-gated-auricular-vagus-afferent-nerve-stimulation-ravans-in-migraine-patients-an-fmri-study
#3
R Garcia, R Lin, J Lee, M Loggia, J Kim, H Kim, A Wasan, R Edwards, N Hadjikhani, V Napadow
No abstract text is available yet for this article.
April 2016: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/28158166/abnormal-local-brain-activity-beyond-the-pain-matrix-in-postherpetic-neuralgia-patients-a-resting-state-functional-mri-study
#4
Song Cao, Ganjun Song, Yi Zhang, Peng Xie, Ye Tu, Ying Li, Tian Yu, Buwei Yu
BACKGROUND: Postherpetic neuralgia (PHN) patients suffer debilitating chronic pain, hyperalgesia, and allodynia, as well as emotional disorders such as insomnia, anxiety, and depression. The brain structure and functional basis of PHN are still not fully understood. OBJECTIVES: To identify the changes of regional brain activity in resting-state PHN patients using regional homogeneity (ReHo) and fractional aptitude of low-frequency fluctuation (fALFF) methods. Correlations between spontaneous pain intensity and ReHo or fALFF were analyzed...
February 2017: Pain Physician
https://www.readbyqxmd.com/read/28131178/cortical-control-of-vertical-and-horizontal-saccades-in-progressive-supranuclear-palsy-an-exploratory-fmri-study
#5
J Lemos, D Pereira, L Almendra, D Rebelo, M Patrício, J Castelhano, G Cunha, C Januário, L Cunha, A Freire, M Castelo-Branco
Progressive supranuclear palsy (PSP) is a neurodegenerative disorder showing predominant brainstem involvement, characterized by marked slowing of rapid eye movements (saccades), particularly along the vertical plane. While the contribution of the brainstem damage for the saccadic disturbance in PSP has been extensively studied, much less is known about its cortical and subcortical pathomechanisms. We measured reflexive (prosaccades) and voluntary (antisaccades) saccades in the vertical and horizontal plane in PSP patients (n=8) and controls (n=10) in an eye tracking study, followed by the measurement of blood oxygenation-level dependent (BOLD) activation (PSP, n=6; controls, n=10) during similar saccade paradigms...
February 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28123019/cortical-correlates-of-the-auditory-frequency-following-and-onset-responses-eeg-and-fmri-evidence
#6
Emily B J Coffey, Gabriella Musacchia, Robert J Zatorre
: The frequency-following response (FFR) is a measure of the brain's periodic sound encoding. It is of increasing importance for studying the human auditory nervous system due to numerous associations with auditory cognition and dysfunction. Although the FFR is widely interpreted as originating from brainstem nuclei, a recent study using MEG suggested that there is also a right-lateralized contribution from the auditory cortex at the fundamental frequency (Coffey et al., 2016b). Our objectives in the present work were to validate and better localize this result using a completely different neuroimaging modality and to document the relationships between the FFR, the onset response, and cortical activity...
January 25, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28104084/access-to-vagal-projections-via-cutaneous-electrical-stimulation-of-the-neck-fmri-evidence-in-healthy-humans
#7
Eleni Frangos, Barry R Komisaruk
BACKGROUND: Stimulation of the vagus nerve via implanted electrodes is currently used to treat refractory epilepsy and depression. Recently, a non-invasive approach to vagal stimulation has demonstrated similar beneficial effects, but it remains unclear whether these effects are mediated via activation of afferent vagal fibers. OBJECTIVE: The present study was designed to ascertain whether afferent vagal projections can be accessed non-invasively by transcutaneous electrical stimulation of the antero-lateral surface of the neck, which overlies the course of the vagus nerve...
January 2017: Brain Stimulation
https://www.readbyqxmd.com/read/28074492/confirmation-of-resting-state-bold-fluctuations-in-the-human-brainstem-and-spinal-cord-after-identification-and-removal-of-physiological-noise
#8
Shreyas Harita, Patrick W Stroman
PURPOSE: Resting-state functional MRI (rs-fMRI) has been used to investigate networks within the cortex, but its use in the brainstem (BS) and spinal cord (SC) has been limited. This region presents challenges for fMRI, partly because of sources of physiological noise. This study aims to quantify noise contributions to rs-fMRI, and to obtain evidence of resting-state blood oxygenation level-dependent (BOLD) fluctuations. METHODS: Resting-state-fMRI data were obtained from the BS/SC in 16 participants, at 3 Tesla, with T2 -weighted single-shot fast spin-echo imaging...
January 11, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28048305/su-f-j-139-amplitude-of-low-frequency-fluctuation-alff-and-regional-homogeneity-reho-study-of-the-respiration-motion-control-byhypnosis
#9
Y Liu, R Li, Y Xie
PURPOSE: Respiration control by hypnosis is a method in reducing the detriment to the healthy organs or organizations for patients during radiotherapy, especially for lung and abdomen cancer (Fig.1). It's hypothesized that there exists alterations neurological brain activity during the hypnosis state of respiratory motion control in comparison with resting state. METHODS: Thirteen healthy volunteers were organized to participate in a hypnosis experiment that consisted of two sectional scans of functional magnetic resonance imaging (fMRI), rest state condition (RSC) scanning and hypnosis state condition (HSC) scanning...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/27980112/cortical-correlates-of-the-auditory-frequency-following-and-onset-responses-eeg-and-fmri-evidence
#10
Emily B J Coffey, Gabriella Musacchia, Robert J Zatorre
: The frequency following response (FFR) is a measure of the brain's periodic sound encoding. It is of increasing importance for studying the human auditory nervous system due to numerous associations with auditory cognition and dysfunction. Although the FFR is widely interpreted as originating from brainstem nuclei, a recent study using magnetoencephalography (MEG) suggested that there is also a right-lateralized contribution from the auditory cortex at the fundamental frequency (Coffey et al...
December 15, 2016: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/27978801/visual-sexual-stimulation-and-erection-a-brief-review-with-new-fmri-data
#11
Sharon L Wu, Maggie Sm Chow, Y L Jiang, Jingjin Yang, Hao Zhou, David T Yew
This review examines brain sites involved in sexual stimulation. New data on brain activation sites in individuals having erections concomitant with visual erotic stimulation was documented. The activation was chiefly at the midbrain around the cerebral peduncle, and in the pons centering on the tegmentum, they are indicated by blood oxygenation level dependent (BOLD) images captured by functional magnetic resonance imaging (fMRI). The cerebellum and inferior temporal lobe were activated more extensively in individuals viewing pornographic movie with a concomitant erection than those without...
December 12, 2016: Current Medicinal Chemistry
https://www.readbyqxmd.com/read/27932883/functional-cortical-changes-in-relapsing-remitting-multiple-sclerosis-at-amplitude-configuration-a-resting-state-fmri-study
#12
Heng Liu, Hua Chen, Bo Wu, Tijiang Zhang, Jinhui Wang, Kexin Huang, Ganjun Song, Jian Zhan
OBJECTIVE: The aim of this study was to explore the amplitude of spontaneous brain activity fluctuations in patients with relapsing-remitting multiple sclerosis (RRMS) using the amplitude of low-frequency fluctuation (ALFF) method. METHODS: ALFF and SPM8 were utilized to assess alterations in regional spontaneous brain activities in patients with RRMS in comparison with healthy controls (HCs). The beta values of altered brain regions between patients with RRMS and HCs were extracted, and a receiver operating characteristic (ROC) curve was generated to calculate the sensitivities and specificities of these different brain areas for distinguishing patients with RRMS from HCs...
2016: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/27929102/functional-connectivity-changes-resemble-patterns-of-ptdp-43-pathology-in-amyotrophic-lateral-sclerosis
#13
Ines Schulthess, Martin Gorges, Hans-Peter Müller, Dorothée Lulé, Kelly Del Tredici, Albert C Ludolph, Jan Kassubek
'Resting-state' fMRI allows investigation of alterations in functional brain organization that are associated with an underlying pathological process. We determine whether abnormal connectivity in amyotrophic lateral sclerosis (ALS) in a priori-defined intrinsic functional connectivity networks, according to a neuropathological staging scheme and its DTI-based tract correlates, permits recognition of a sequential involvement of functional networks. 'Resting-state' fMRI data from 135 ALS patients and 56 matched healthy controls were investigated for the motor network (corresponding to neuropathological stage 1), brainstem (stage 2), ventral attention (stage 3), default mode/hippocampal network (stage 4), and primary visual network (as the control network) in a cross-sectional analysis and longitudinally in a subgroup of 27 patients after 6 months...
December 8, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27907094/continuous-descending-modulation-of-the-spinal-cord-revealed-by-functional-mri
#14
Patrick W Stroman, Rachael L Bosma, Andreea I Cotoi, Roxanne H Leung, Jennifer Kornelsen, Jane M Lawrence-Dewar, Caroline F Pukall, Roland Staud
Spontaneous variations in spinal cord activity may arise from regulation of any of a number of functions including sensory, motor, and autonomic control. Here, we use functional MRI (fMRI) of healthy participants to identify properties of blood oxygenation-level dependent (BOLD) variations in the spinal cord in response to knowledge that either a noxious stimulus is impending, or that no stimulus is to be expected. Expectation of a noxious stimulus, or no stimulus, is shown to have a significant effect on wide-spread BOLD signal variations in the spinal cord over the entire time period of the fMRI acquisition...
2016: PloS One
https://www.readbyqxmd.com/read/27898202/optimization-of-transcutaneous-vagus-nerve-stimulation-using-functional-mri
#15
Natalia Yakunina, Sam Soo Kim, Eui-Cheol Nam
OBJECTIVE/HYPOTHESIS: Vagus nerve stimulation (VNS) is an established therapy for drug-resistant epilepsy, depression, and a number of other disorders. Transcutaneous stimulation of the auricular branch of the vagus nerve (tVNS) has been considered as a non-invasive alternative. Several functional magnetic resonance imaging (fMRI) studies on the effects of tVNS used different stimulation parameters and locations in the ear, which makes it difficult to determine the optimal tVNS methodology...
November 29, 2016: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/27881783/multivariate-brain-prediction-of-heart-rate-and-skin-conductance-responses-to-social-threat
#16
Hedwig Eisenbarth, Luke J Chang, Tor D Wager
: Psychosocial stressors induce autonomic nervous system (ANS) responses in multiple body systems that are linked to health risks. Much work has focused on the common effects of stress, but ANS responses in different body systems are dissociable and may result from distinct patterns of cortical-subcortical interactions. Here, we used machine learning to develop multivariate patterns of fMRI activity predictive of heart rate (HR) and skin conductance level (SCL) responses during social threat in humans (N = 18)...
November 23, 2016: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/27859973/reorganization-of-brain-connectivity-in-obesity
#17
Paul Geha, Guillermo Cecchi, R Todd Constable, Chadi Abdallah, Dana M Small
Global brain connectivity (GBC) identifies regions of the brain, termed "hubs," which are densely connected and metabolically costly, and have a wide influence on brain function. Since obesity is associated with central and peripheral metabolic dysfunction we sought to determine if GBC is altered in obesity. Two independent fMRI data sets were subjected to GBC analyses. The first data set was acquired while participants (n = 15 healthy weight and 15 obese) tasted milkshake and the second with participants at rest (n = 33 healthy weight and 28 obese)...
November 16, 2016: Human Brain Mapping
https://www.readbyqxmd.com/read/27853428/goal-directed-worry-rules-are-associated-with-distinct-patterns-of-amygdala-functional-connectivity-and-vagal-modulation-during-perseverative-cognition
#18
Frances Meeten, Graham C L Davey, Elena Makovac, David R Watson, Sarah N Garfinkel, Hugo D Critchley, Cristina Ottaviani
Excessive and uncontrollable worry is a defining feature of Generalized Anxiety Disorder (GAD). An important endeavor in the treatment of pathological worry is to understand why some people are unable to stop worrying once they have started. Worry perseveration is associated with a tendency to deploy goal-directed worry rules (known as "as many as can" worry rules; AMA). These require attention to the goal of the worry task and continuation of worry until the aims of the "worry bout" are achieved. This study examined the association between the tendency to use AMA worry rules and neural and autonomic responses to a perseverative cognition induction...
2016: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/27843697/filtering-and-storage-working-memory-networks-in-younger-and-older-age
#19
Anne-Katrin Vellage, Andreas Becke, Hendrik Strumpf, Bernhard Baier, Mircea Ariel Schönfeld, Jens-Max Hopf, Notger G Müller
INTRODUCTION: Working memory (WM) is a multi-component model that among others involves the two processes of filtering and storage. The first reflects the necessity to inhibit irrelevant information from entering memory, whereas the latter refers to the active maintenance of object representations in memory. In this study, we aimed at a) redefining the neuronal networks sustaining filtering and storage within visual working memory by avoiding shortcomings of prior studies, and b) assessing age-related changes in these networks...
November 2016: Brain and Behavior
https://www.readbyqxmd.com/read/27803653/probing-intrinsic-resting-state-networks-in-the-infant-rat-brain
#20
Dusica Bajic, Michael M Craig, David Borsook, Lino Becerra
Resting-state functional magnetic resonance imaging (rs-fMRI) measures spontaneous fluctuations in blood oxygenation level-dependent (BOLD) signal in the absence of external stimuli. It has become a powerful tool for mapping large-scale brain networks in humans and animal models. Several rs-fMRI studies have been conducted in anesthetized and awake adult rats, reporting consistent patterns of brain activity at the systems level. However, the evolution to adult patterns of resting-state activity has not yet been evaluated and quantified in the developing rat brain...
2016: Frontiers in Behavioral Neuroscience
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