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https://www.readbyqxmd.com/read/27904123/posterior-reversible-encephalopathy-syndrome-with-extensive-deep-white-matter-lesions-including-the-temporal-pole
#1
Junichiro Ohira, Nobuyuki Mori, Shunsuke Kajikawa, Takeshi Nakamura, Tetsuya Arisato, Makio Takahashi
Posterior reversible encephalopathy syndrome (PRES) typically affects the posterior subcortical white matter. We report the case of a 55-year-old man with atypical PRES, who had malignant hypertension and renal dysfunction. Magnetic resonance imaging of the brain revealed extensive vasogenic edema in the deep white matter including the temporal pole, as well as in the brainstem and cerebellum. Antihypertensive therapy and hemodialysis contributed to both clinical and radiological improvement. Involvement of the deep white matter including the temporal pole, which is rarely affected in an ischemic stroke, should be recognized as a potential sign of PRES...
2016: Internal Medicine
https://www.readbyqxmd.com/read/27851391/1756-listeria-rhomboencephalitis-initially-diagnosed-as-a-brainstem-stroke
#2
La Von Ross, Nakita Barnes, Judson Lewis, Jenna Foster, William Owens
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27824157/effect-of-p22phox-depletion-on-sympathetic-regulation-of-blood-pressure-in-shrsp-evaluation-in-a-new-congenic-strain
#3
Hasan M Zahid, Mohammed Zubaerul Ferdaus, Hiroki Ohara, Minoru Isomura, Toru Nabika
Oxidative stress in the rostral ventrolateral medulla (RVLM), a sympathetic center in the brainstem, was implicated in the regulation of sympathetic activity in various hypertensive models including stroke-prone spontaneously hypertensive rats (SHRSP). In this study, we evaluated the role of the NADPH oxidases (NOX) in the blood pressure (BP) regulation in RVLM in SHRSP. The P22PHOX-depleted congenic SHRSP (called SP.MES) was constructed by introducing the mutated p22phox gene of Matsumoto Eosinophilic Shinshu rat...
November 8, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27800660/treatment-of-severe-adult-traumatic-brain-injury-using-bone-marrow-mononuclear-cells
#4
Charles S Cox, Robert A Hetz, George P Liao, Benjamin M Aertker, Linda Ewing-Cobbs, Jenifer Juranek, Sean I Savitz, Margaret L Jackson, Anna M Romanowska-Pawliczek, Fabio Triolo, Pramod K Dash, Claudia Pedroza, Dean A Lee, Laura Worth, Imoigele P Aisiku, Huimahn A Choi, John B Holcomb, Ryan S Kitagawa
BACKGROUND: Numerous pre-clinical studies using bone marrow derived cells for the treatment of traumatic brain injury and stroke have demonstrated efficacy in terms of blood-brain barrier preservation, neurogenesis, and other functional outcomes. Phase 1 clinical trials using bone marrow mononuclear cells infused intravenously in children with severe TBI demonstrated safety and potentially a CNS structural preservation treatment effect. This study sought to confirm the safety, logistic feasibility, and potential treatment effect size of structural preservation/inflammatory biomarker mitigation in adults to guide Phase 2 clinical trial design...
November 1, 2016: Stem Cells
https://www.readbyqxmd.com/read/27800191/successful-left-atrial-appendage-occlusion-with-the-new-generation-amulet%C3%A2-device-after-late-occurring-embolization-of-an-amplatzer%C3%A2-cardiac-plug-in-a-patient-with-repetitive-strokes
#5
Marco R Schroeter, Wolfgang Schillinger
The Amplatzer Cardiac Plug (ACP) is one of the most commonly used devices for percutaneous left atrial appendage (LAA) closure in order to prevent a stroke in patients with atrial fibrillation and contraindication for long-term oral anticoagulation therapy. We have previously described a patient who had experienced an embolization of the ACP device about 12 months after implantation and the device could be percutaneously retrieved. A few years later, he suffered from a posterior stroke and a stroke located in the brainstem as well as a transischemic attack (TIA)...
2016: Case Reports in Cardiology
https://www.readbyqxmd.com/read/27798137/spike-timing-dependent-plasticity-in-the-long-latency-stretch-reflex-following-paired-stimulation-from-a-wearable-electronic-device
#6
K M Riashad Foysal, Felipe de Carvalho, Stuart N Baker
: The long-latency stretch reflex (LLSR) in human elbow muscles probably depends on multiple pathways; one possible contributor is the reticulospinal tract. Here we attempted to induce plastic changes in the LLSR by pairing noninvasive stimuli that are known to activate reticulospinal pathways, at timings predicted to cause spike timing-dependent plasticity in the brainstem. In healthy human subjects, reflex responses in flexor muscles were recorded following extension perturbations at the elbow...
October 19, 2016: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/27781047/functional-independence-following-endovascular-treatment-for-basilar-artery-occlusion-despite-extensive-bilateral-pontine-infarcts-on-diffusion-weighted-imaging-refuting-a-self-fulfilling-prophecy
#7
Diogo C Haussen, Renato A C Oliveira, Vikas Patel, Raul G Nogueira
BACKGROUND AND PURPOSE: Extensive brainstem diffusion-weighted imaging (DWI) hyperintensity has been associated with poor outcomes. We aim at documenting a series of patients with extensive DWI pontine lesions who achieved independence following endovascular therapy and aggressive medical therapy in the setting of posterior circulation basilar artery occlusion (BAO). METHODS: This is a retrospective endovascular database review of a single-operator experience over a 9-year period for patients with (1) complete BAO, (2) extensive bilateral pontine DWI changes and (3) 90-day modified Rankin scale 0-2...
September 2016: Interventional Neurology
https://www.readbyqxmd.com/read/27772756/hypertrophic-olivary-degeneration-case-series-and-review-of-literature
#8
Shyam Sabat, Neil Mannering, Amit Agarwal
Hypertrophic Olivary Degeneration (HOD) is a rare neurological condition caused by trans-synaptic degeneration in the brainstem and cerebellum, resulting in varied clinical symptoms, classical being palatal tremors, along with characteristic imaging presentation. Large number of pathologic lesions can cause this condition, ranging from ischemic stroke to neoplasm. The most common conditions include hemorrhage, vascular malformations and infarct. Magnetic resonance scan (MRI) is the imaging modality of choice which shows signal changes with hypertrophy of the inferior olivary nucleus, as well as the primary underlying pathology...
November 15, 2016: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/27743373/depression-and-anxiety-symptoms-are-associated-to-disruption-of-default-mode-network-in-subacute-ischemic-stroke
#9
Jéssica Elias Vicentini, Marina Weiler, Sara Regina Meira Almeida, Brunno Machado de Campos, Lenise Valler, Li Min Li
Depression and anxiety symptoms are common after stroke and associated to reduction in quality of life and poor physical and social outcomes. The Default Mode Network (DMN) plays an important role in the emotional processing. We investigated whether these symptoms are associated to a disruption of DMN functional connectivity in the first month after stroke. Thirty-four subacute ischemic stroke patients were submitted to: 1) behavioral assessment through Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI) and Structured Clinical Interview for DSM Disorders; 2) neuropsychological assessment using Mini Mental State Examination and Montreal Cognitive Assessment; 3) resting state functional magnetic resonance imaging acquisition using a 3 T scanner (Philips Achieva)...
October 14, 2016: Brain Imaging and Behavior
https://www.readbyqxmd.com/read/27737957/untreated-hypertension-a-powerful-risk-factor-for-lobar-and-nonlobar-intracerebral-hemorrhage-in-whites-blacks-and-hispanics
#10
Kyle B Walsh, Daniel Woo, Padmini Sekar, Jennifer Osborne, Charles J Moomaw, Carl D Langefeld, Opeolu Adeoye
BACKGROUND: Hypertension is a significant risk factor for intracerebral hemorrhage (ICH). Although ethnic/racial disparities related to hypertension and ICH have been reported, these previous studies were limited by a lack of Hispanics and inadequate power to analyze by ICH location. In the current study, while overcoming these prior limitations, we investigated whether there was variation by ethnicity/race of treated and untreated hypertension as risk factors for ICH. METHODS: The ERICH study (Ethnic/Racial Variations of Intracerebral Hemorrhage) is a prospective, multicenter, case-control study of ICH among whites, blacks, and Hispanics...
November 8, 2016: Circulation
https://www.readbyqxmd.com/read/27712791/posterior-fossa-tumors-in%C3%A2-adult-patients
#11
Robert Y Shih, James G Smirniotopoulos
In adults, the most common expansile "mass" lesion in the posterior fossa is a subacute stroke, whereas the most common neoplastic lesion in the posterior fossa is cerebellar metastasis (intra-axial) or vestibular schwannoma (extra-axial). Those diseases fall outside the scope of this article, which focuses on primary intra-axial tumors of the posterior fossa in adults. This category of tumors is uncommon and more frequently encountered in children. This article reviews tumors of the cerebellum, brainstem, and fourth ventricle that are seen in adult patients, following categories from the 2007 World Health Organization classification of central nervous system tumors...
November 2016: Neuroimaging Clinics of North America
https://www.readbyqxmd.com/read/27704247/childhood-acute-basilar-artery-thrombosis-successfully-treated-with-mechanical-thrombectomy-using-stent-retrievers-case-report-and-review-of-the-literature
#12
Giancarlo Nicosia, Domenico Cicala, Giuseppe Mirone, Pietro Spennato, Vincenzo Trischitta, Claudio Ruggiero, Gianluigi Guarneri, Mario Muto, Giuseppe Cinalli
INTRODUCTION: Acute basilar artery occlusion (ABAO) is an infrequent but potentially fatal cause of strokes in both adults and children, and it is usually due to vertebral artery dissection (VAD). VAD has been found to be usually a consequence of traumatic vertebral artery injury. ABAO usually presents with symptoms of acute ischemic stroke (AIS) of the posterior circulation or transient ischemic attack (TIA). It may lead to death or long-term disability if not promptly recanalized. Basilar artery recanalization in children can be achieved safely and with excellent clinical outcome using endovascular thrombectomy with the new generation self-expanding and retrievable stents...
October 4, 2016: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/27698507/case-study-of-fatal-stroke-following-intranasal-lidocaine
#13
Daniel L Moellentin, Dale Stewart, James Barbour
A 39-year-old man presented with new onset right hemiparesis and aphasia within an hour of using approximately 120 mL lidocaine 4% topical solution intranasally. Lidocaine had been prescribed over a 3-week period for pain due to multiple debridements of the nasal septum. A total of 650 mL of 4% lidocaine (26 g) had been dispensed to the patient during this time. The patient had a significant history of drug abuse, including snorting crushed tablets. Otherwise he was a healthy man with no chronic diseases or conditions...
September 2016: Hospital Pharmacy
https://www.readbyqxmd.com/read/27698280/ct-angiography-source-images-indicate-less-fatal-outcome-despite-coma-of-patients-in-the-basilar-artery-international-cooperation-study
#14
Lars P Pallesen, Andrei Khomenko, Imanuel Dzialowski, Jessica Barlinn, Kristian Barlinn, Charlotte Zerna, Erik Jrj van der Hoeven, Ale Algra, L Jaap Kapelle, Patrik Michel, Ulf Bodechtel, Andrew M Demchuk, Wouter Schonewille, Volker Puetz
BACKGROUND: Coma is associated with poor outcome in patients with basilar artery occlusion. AIMS: We sought to assess whether the posterior circulation Acute Stroke Prognosis Early CT Score and the Pons-Midbrain Index applied to CT angiography source images predict the outcome of comatose patients in the Basilar Artery International Cooperation Study. METHODS: Basilar Artery International Cooperation Study was a prospective, observational registry of patients with acute basilar artery occlusion with 48 recruiting centers worldwide...
October 3, 2016: International Journal of Stroke: Official Journal of the International Stroke Society
https://www.readbyqxmd.com/read/27677007/efficiency-of-physical-rehabilitation-on-postural-imbalance-after-stroke-systematic-review-and-meta-analysis
#15
Aurelien Hugues, Julie Di Marco, Perrine Janiaud, Isabelle Bonan, Francois Gueyffier, Gilles Rode
OBJECTIVE: Balance disorders are frequently seen after stroke resulting in limited physical activities. The effects of current physical rehabilitations aiming at reducing postural imbalance are varied with low levels of evidence. OBJECTIVES: i) to determine the efficiency of physical rehabilitation methods on the recovery of postural imbalance in patients after stroke; ii) to assess which method is more effective when compared with one another. MATERIAL/PATIENTS AND METHODS: Search strategy: we searched Medline, Embase, Pedro, Cochrane Central Register of Controlled Trials, Pascal and Francis from inception to October 2015...
September 2016: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/27676979/visual-verticality-perception-after-stroke-a-systematic-review-of-methodological-approaches-and-suggestions-for-standardization
#16
Dominic Pérennou, Céline Piscicelli
OBJECTIVE: Visual vertical (VV) measurements are being increasingly used for routine clinical assessment of spatial cognition, to investigate otolithic vestibular function and identify altered verticality perception as a possible cause of postural disorders after stroke. The objective of this paper was to synthesize knowledge of assessment methods for testing VV after stroke. MATERIAL/PATIENTS AND METHODS: This systematic review, following the PRISMA statement, involved a search for articles in Medline via PubMed published up to November 2015 by using the search terms "visual vertical", "verticality perception" and "stroke"...
September 2016: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/27663557/traumatic-basilar-artery-entrapment-with-patency-of-pontine-perforators-and-absence-of-significant-brainstem-infarction-report-of-an-unusual-case
#17
Stefan Kliesch, Christian Bauknecht, Georg Bohner, Thomas Liebig, Eberhard Siebert
We report a rare case of entrapment of the basilar artery into the sphenoid bone caused by a longitudinal fracture of the clivus. Using high resolution three-dimensional flat panel angiography, we show preservation of the basilar artery perforators in spite of severe stenosis of the entrapped segment of the basilar artery. There were no obvious signs and symptoms of posterior fossa stroke clinically or radiographically as far as could be assessed under given clinical circumstances.
September 23, 2016: Journal of Neurointerventional Surgery
https://www.readbyqxmd.com/read/27651328/diagnostic-accuracy-of-whole-brain-ct-perfusion-in-the-detection-of-acute-infratentorial-infarctions
#18
Christine Bollwein, Annika Plate, Wieland H Sommer, Kolja M Thierfelder, Hendrik Janssen, Maximilian F Reiser, Andreas Straube, Louisa von Baumgarten
INTRODUCTION: Although the diagnostic performance of whole-brain computed tomographic perfusion (WB-CTP) in the detection of supratentorial infarctions is well established, its value in the detection of infratentorial strokes remains less well defined. We examined its diagnostic accuracy in the detection of infratentorial infarctions and compared it to nonenhanced computed tomography (NECT), aiming to identify factors influencing its detection rate. METHODS: Out of a cohort of 1380 patients who underwent WB-CTP due to suspected stroke, we retrospectively included all patients with MRI-confirmed infratentorial strokes and compared it to control patients without infratentorial strokes...
November 2016: Neuroradiology
https://www.readbyqxmd.com/read/27646318/traumatic-basilar-artery-entrapment-with-patency-of-pontine-perforators-and-absence-of-significant-brainstem-infarction-report-of-an-unusual-case
#19
Stefan Kliesch, Christian Bauknecht, Georg Bohner, Thomas Liebig, Eberhard Siebert
We report a rare case of entrapment of the basilar artery into the sphenoid bone caused by a longitudinal fracture of the clivus. Using high resolution three-dimensional flat panel angiography, we show preservation of the basilar artery perforators in spite of severe stenosis of the entrapped segment of the basilar artery. There were no obvious signs and symptoms of posterior fossa stroke clinically or radiographically as far as could be assessed under given clinical circumstances.
2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27638081/ischemic-syndromes-causing-dizziness-and-vertigo
#20
K-D Choi, H Lee, J-S Kim
Dizziness/vertigo and imbalance are the most common symptoms of vertebrobasilar ischemia. Even though dizziness/vertigo usually accompanies other neurologic symptoms and signs in cerebrovascular disorders, a diagnosis of isolated vascular vertigo is increasing markedly by virtue of recent developments in clinical neurotology and neuroimaging. It is important to differentiate isolated vertigo of a vascular cause from more benign disorders involving the inner ear, since therapeutic strategies and prognosis differ between these two conditions...
2016: Handbook of Clinical Neurology
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