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https://www.readbyqxmd.com/read/28729461/morphology-of-the-archaellar-motor-and-associated-cytoplasmic-cone-in-thermococcus-kodakaraensis
#1
Ariane Briegel, Catherine M Oikonomou, Yi-Wei Chang, Andreas Kjær, Audrey N Huang, Ki Woo Kim, Debnath Ghosal, Hong H Nguyen, Dorothy Kenny, Rachel R Ogorzalek Loo, Robert P Gunsalus, Grant J Jensen
Archaeal swimming motility is driven by archaella: rotary motors attached to long extracellular filaments. The structure of these motors, and particularly how they are anchored in the absence of a peptidoglycan cell wall, is unknown. Here, we use electron cryotomography to visualize the archaellar basal body in vivo in Thermococcus kodakaraensis KOD1. Compared to the homologous bacterial type IV pilus (T4P), we observe structural similarities as well as several unique features. While the position of the cytoplasmic ATPase appears conserved, it is not braced by linkages that extend upward through the cell envelope as in the T4P, but rather by cytoplasmic components that attach it to a large conical frustum up to 500 nm in diameter at its base...
July 19, 2017: EMBO Reports
https://www.readbyqxmd.com/read/28726053/the-effect-of-different-ankle-and-knee-supports-on-balance-in-early-ambulation-of-post-stroke-hemiplegic-patients
#2
Burcu Talu, Zilan Bazancir
The purpose of this study was to compare the effects of different ankle and knee supports on balance in early ambulation of post-stroke hemiplegic patients. This is a randomized experimental study. The study sample included 20 hemiplegic patients who were able to stand with support and who had been diagnosed with a cerebrovascular accident within the last month. A knee immobilization brace (KIB) was first placed on each individual (first application), followed by placement of knee immobilizer brace and Foot Lifter Orthosis ® (FLO) (second application), and lastly, placement of KIB and rigid taping (RT) (third application)...
July 19, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28720985/conservative-management-of-odontoid-peg-fractures-long-term-follow-up
#3
REVIEW
Aheed Osman, Nabil A Alageli, D J Short, W S El Masri
OBJECTIVE: The aim of the study was to look at the long-term effects of conservative management of odontoid peg fractures. METHODS: We reviewed 48 consecutive patients with type II (32) and 16 type III, odontoid peg fractures. The clinical & radiological outcomes were assessed over an average period of follow up of 8 years. Union rate was determined and we discussed several factors that may affect it. Patients were treated conservatively with an average period of bed rest of 4 weeks followed by bracing for an average of 9 weeks...
April 2017: Journal of Clinical Orthopaedics and Trauma
https://www.readbyqxmd.com/read/28718240/ponseti-technique-for-management-of-congenital-idiopathic-club-foot
#4
Muhammad Qaisar Shah, Alamzeb Khan, Muhammad Shoaib Zardad, Rizwana Iqbal, Sajjad Ahmed
BACKGROUND: Clubfoot or congenital talipes equinovarus, is a congenital deformity of the foot. It consists of cavus, adduction, varus and equinus. This is due to medial displacement of navicular and calcaneus around the talus. Talus is in equinus. Medial deviation of the head and neck of talus is due to force of calcaneus on talus. METHODS: This descriptive case series study was conducted at Orthopaedic unit, Ayub Teaching Hospital, Abbottabad from 1st August 2015 to 31st January 2016 to determine the frequency of idiopathic clubfoot correction, by using the Ponseti method...
April 2017: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/28716073/surgical-correction-of-hyperlordosis-in-facioscapulohumeral-muscular-dystrophy-a-case-report
#5
Haining Tan, Fan Feng, Youxi Lin, Chong Chen, Zheng Li, Jianxiong Shen
BACKGROUND: Hyperlordosis is common in facioscapulohumeral muscular dystrophy (FSHD), which cannot be controlled by bracing. While the surgical treatment is neither reported nor recommended in previous studies, we report the first corrective surgery for hyperlordosis in one wheelchair-dependent FSHD patient. CASE PRESENTATION: A 15-year-old, wheelchair-dependent girl complaining of hyperlordosis and lower extremity weakness was diagnosed as FSHD. Preoperative examination showed hyperlordosis of 116° with scoliosis of 44°...
July 17, 2017: BMC Surgery
https://www.readbyqxmd.com/read/28714786/effects-of-a-prophylactic-knee-sleeve-on-anterior-cruciate-ligament-loading-during-sport-specific-movements
#6
Jonathan Sinclair, Paul John Taylor
CONTEXT: Prophylactic knee bracing is extensively utilized in athletic populations, to reduce the high risk from knee injuries, but their role in the attenuation of anterior cruciate ligament (ACL) pathologies is not well understood. OBJECTIVE: The aim of the current investigation was to investigate the effects of a prophylactic knee sleeve on ACL loading parameters linked to the aetiology of injury in recreational athletes. SETTING: Laboratory...
July 17, 2017: Journal of Sport Rehabilitation
https://www.readbyqxmd.com/read/28714764/abdominal-hollowing-reduces-lateral-trunk-displacement-during-single-leg-squats-in-healthy-females-but-does-not-affect-peak-hip-abduction-angle-or-knee-abductio-angle-moment
#7
Lukas D Linde, Jessica Archibald, Eve C Lampert, John Z Srbely
CONTEXT: Females suffer 4-6 times more non-contact anterior cruciate ligament (ACL) injuries than males due to neuromuscular control deficits of the hip musculature leading to increases in hip adduction angle, knee abduction angle, and knee abduction moment during dynamic tasks such as single-leg squats. Lateral trunk displacement has been further related to ACL injury risk in females, leading to the incorporation of core strength/stability exercises in ACL preventative training programs...
July 17, 2017: Journal of Sport Rehabilitation
https://www.readbyqxmd.com/read/28710344/position-of-immobilization-after-first-time-traumatic-anterior-glenohumeral-dislocation-a-literature-review
#8
Olga Gutkowska, Jacek Martynkiewicz, Jerzy Gosk
Anterior glenohumeral dislocation affects about 2% of the general population during the lifetime. The incidence of traumatic glenohumeral dislocation ranges from 8.2 to 26.69 per 100 000 population per year. The most common complication is recurrent dislocation occurring in 17-96% of the patients. The majority of patients are treated conservatively by closed reduction and immobilization in internal rotation for 2-3 weeks. However, no clear conservative treatment protocol exists. Immobilization in external rotation can be considered an alternative...
July 15, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/28706550/effect-of-acupressure-on-early-complications-of-menopause-in-women-referring-to-selected-health-care-centers
#9
Maryam Armand, Gity Ozgoli, Reza Heshmat Giti, Hamid Alavi Majd
BACKGROUND: Menopausal period is accompanied by numerous disorders and complications. Nowadays, hormone therapy is the most effective existing method to treat these complications, but many women cannot undergo that due to the known potentiality of risk. So, the present study aimed to investigate the effect of acupressure on early complications of menopause. MATERIALS AND METHODS: This is a blind random clinical trial conducted on 70 menopaused women referring to selected health care centers in Tehran who were qualified to enter the study...
May 2017: Iranian Journal of Nursing and Midwifery Research
https://www.readbyqxmd.com/read/28704635/rehabilitation-and-improvement-of-health-related-quality-of-life-detriments-in-individuals-with-chronic-ankle-instability-a-meta-analysis
#10
Cameron J Powden, Johanna M Hoch, Matthew C Hoch
OBJECTIVE:   To conduct a systematic review with meta-analysis assessing the effectiveness of conservative rehabilitation programs for improving health-related quality of life (HRQL) in individuals with chronic ankle instability (CAI). DATA SOURCES:   PubMed, MEDLINE, CINAHL, and SPORTDiscus were searched from inception to January 2016. STUDY SELECTION:   Studies were included if the researchers examined the effects of a conservative rehabilitation protocol in individuals with CAI, used validated patient-reported outcomes (PROs) to quantify participant-perceived HRQL, and provided adequate data to calculate the effect sizes (ESs) and 95% confidence intervals (CIs)...
July 13, 2017: Journal of Athletic Training
https://www.readbyqxmd.com/read/28701689/lybatides-from-lycium-barbarum-contain-an-unusual-cystine-stapled-helical-peptide-scaffold
#11
Wei Liang Tan, Ka H Wong, Jian Lei, Naoki Sakai, Hong Wei Tan, Rolf Hilgenfeld, James P Tam
Cysteine-rich peptides (CRPs) of 2-6 kDa are generally thermally and proteolytically stable because of their multiple cross-bracing disulfide bonds. Here, we report the discovery and characterization of two novel cystine-stapled CRPs, designated lybatide 1 and 2 (lyba1 and lyba2), from the cortex of Lycium barbarum root. Lybatides, 32 to 33 amino acids in length, are hyperstable and display a novel disulfide connectivity with a cysteine motif of C-C-C-C-CC-CC which contains two pairs of adjacent cysteines (-CC-CC)...
July 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28697399/patellar-bracing-affects-semg-activity-of-leg-and-thigh-muscles-during-stance-phase-in-patellofemoral-pain-syndrome
#12
Fatemeh Salarie Sker, Mehrdad Anbarian, Amir H Yazdani, Pouria Hesari, Arash Babaei-Ghazani
BACKGROUND: Decreases in patellofemoral pain symptoms with bracing treatment have been established; but, the mechanisms remain unclear. The purpose of this study was to determine the immediate and long-term effects of the patellar bracing on electromyography (EMG) activity of the Vastus Medialis (VM) and Lateralis (VL), Rectus Femoris, lateral Gastrocnemius, Biceps Femoris and Semitendinosus (ST) muscles during level walking. METHODS: 12 eligible women aged 20-30 years with diagnosis of patellofemoral pain participated in the before and after study...
June 29, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28694598/successful-brace-treatment-of-scheuermann-s-kyphosis-with-different-angles
#13
Mohammad Reza Etemadifar, Mohammad Hossein Jamalaldini, Rasoul Layeghi
BACKGROUND: Scheuermann's disease is regarded as the most common cause of structural hyperkyphosis within adolescents without any proper treatment. It may lead to progressive deformity and back pain which influences patient's quality of life during adolescence and adulthood. Treatment approach to Scheuermann's kyphosis has not been clearly defined due to its different definitions and obscure natural history. The goal of treatment is not only to prevent progression but also to obtain permanent correction...
April 2017: Journal of Craniovertebral Junction and Spine
https://www.readbyqxmd.com/read/28694341/open-reduction-and-internal-fixation-of-humeral-shaft-fractures-versus-conservative-treatment-with-a-functional-brace-a-study-protocol-of-a-randomised-controlled-trial-embedded-in-a-cohort
#14
Lasse Rämö, Simo Taimela, Vesa Lepola, Antti Malmivaara, Tuomas Lähdeoja, Mika Paavola
INTRODUCTION: Humeral shaft fractures represent 1%-3% of all fractures and 20% of humeral fractures in adults. The treatment of these fractures is mainly conservative and operative treatment is usually reserved for specific circumstances. To date, no randomised controlled trial (RCT) has compared operative treatment of humeral shaft fractures with conservative treatment. METHODS AND ANALYSIS: We will conduct an RCT to compare the effectiveness and cost-effectiveness of surgical and conservative treatment of humeral shaft fractures...
July 9, 2017: BMJ Open
https://www.readbyqxmd.com/read/28689046/post-admission-outcomes-of-participants-in-the-paramedic-trial-a-cluster-randomised-trial-of-mechanical-or-manual-chest-compressions
#15
Chen Ji, R Lall, T Quinn, C Kaye, K Haywood, J Horton, V Gordon, C D Deakin, H Pocock, A Carson, M Smyth, N Rees, Kyee Han, S Byers, S Brace-McDonnell, S Gates, G D Perkins
BACKGROUND: The PARAMEDIC cluster randomised trial evaluated the LUCAS mechanical chest compression device, and did not find evidence that use of mechanical chest compression led to an improvement in survival at 30 days. This paper reports patient outcomes from admission to hospital to 12 months after randomisation. METHODS: Information about hospital length of stay and intensive care management were obtained through linkage with Hospital Episode Statistics and the Intensive Care National Audit and Research Centre...
July 5, 2017: Resuscitation
https://www.readbyqxmd.com/read/28687317/effect-of-soft-braces-on-pain-and-physical-function-in-patients-with-knee-osteoarthritis-systematic-review-with-meta-analyses
#16
REVIEW
Tomasz Cudejko, Martin van der Esch, Marike van der Leeden, Leo D Roorda, Jari Pallari, Kim L Bennell, Hans Lund, Joost Dekker
OBJECTIVE: To systematically review and synthesize the effect of soft braces on pain, and self-reported and performance-based physical function in patients with knee osteoarthritis. DATA SOURCES: The following electronic databases were searched from inception to April 20, 2016: The Cochrane Central Registry for Controlled Trials (CENTRAL), PubMed, EMBASE, CINAHL, SportDiscuss, Web of Science and PEDro. STUDY SELECTION: Randomized controlled trials (RCT) and non-randomized controlled trials (non-RCTs), such as controlled clinical trials, crossover studies and case-control studies were included...
July 4, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28682854/medical-device-related-pressure-injuries-in-long-term-acute-care-hospital-setting
#17
Mary Arnold-Long, Melissa Ayer, Kathleen Borchert
PURPOSE: The purpose of this study was to examine the epidemiology of medical device-related pressure injuries (MDRPIs) in 3 long-term acute care hospitals (LTACHs). DESIGN: Retrospective descriptive study. SUBJECTS AND SETTING: The sample comprised 304 adult inpatients at 3 geographically diverse LTACHs: Spaulding Hospital for Continued Medical Care, Drake Center, and Bethesda Hospital. The facilities are located in the Northeastern, Southeastern, and Midwestern United States...
July 2017: Journal of Wound, Ostomy, and Continence Nursing
https://www.readbyqxmd.com/read/28677008/pigment-structure-in-the-violaxanthin-chlorophyll-a-binding-protein-vcp
#18
Manuel J Llansola-Portoles, Radek Litvin, Cristian Ilioaia, Andrew A Pascal, David Bina, Bruno Robert
Resonance Raman spectroscopy was used to evaluate pigment-binding site properties in the violaxanthin-chlorophyll-a-binding protein (VCP) from Nannochloropsis oceanica. The pigments bound to this antenna protein are chlorophyll-a, violaxanthin, and vaucheriaxanthin. The molecular structures of bound Chl-a molecules are discussed with respect to those of the plant antenna proteins LHCII and CP29, the crystal structures of which are known. We show that three populations of carotenoid molecules are bound by VCP, each of which is in an all-trans configuration...
July 4, 2017: Photosynthesis Research
https://www.readbyqxmd.com/read/28670358/aesthetic-treatment-of-bruxism
#19
REVIEW
Shino Bay Aguilera, Liza Brown, Viviana Andrea Perico
Bruxism is a diurnal or nocturnal parafunctional activity that includes unconscious clenching, grinding, or bracing of the teeth. An extensive medical history should be taken in these patients so proper diagnosis can be made. Habits such as biting the tongue, cheeks or lips, chewing gum or eating seeds for many hours per day, biting nails, and/or biting hard objects, will cause and/or exacerbate pre-existing bruxism. The etiology of bruxism is uncertain, but it is hypothesized to be associated with genetic, structural, and psychosocial factors...
May 2017: Journal of Clinical and Aesthetic Dermatology
https://www.readbyqxmd.com/read/28667397/delayed-union-of-humeral-shaft-fractures-comparison-of-autograft-with-and-without-platelet-rich-plasma-treatment-a-randomized-single-blinded-clinical-trial
#20
Carlos Acosta-Olivo, Abiel Garza-Borjon, Mario Simental-Mendia, Felix Vilchez-Cavazos, Yadira Tamez-Mata, Victor Peña-Martinez
INTRODUCTION: Despite an adequate orthopedic treatment with functional bracing, some patients develop a delayed union in humeral shaft fractures. The objective of the present study was to determine the bone consolidation time among patients with delayed union of diaphyseal humeral fractures who were managed with locking compression plate (LCP) fixation combined with an iliac crest autograft using platelet-rich plasma (PRP) as a co-adjuvant. MATERIALS AND METHODS: This study was a controlled, randomized, experimental, longitudinal, comparative, prospective, blind clinical trial...
June 30, 2017: Archives of Orthopaedic and Trauma Surgery
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