keyword
MENU ▼
Read by QxMD icon Read
search

stapes

keyword
https://www.readbyqxmd.com/read/28646272/rhesus-cochlear-and-vestibular-functions-are-preserved-after-inner-ear-injection-of-saline-volume-sufficient-for-gene-therapy-delivery
#1
Chenkai Dai, Mohamed Lehar, Daniel Q Sun, Lani Swarthout Rvt, John P Carey, Tim MacLachlan, Doug Brough, Hinrich Staecker, Alexandra M Della Santina, Timothy E Hullar, Charles C Della Santina
Sensorineural losses of hearing and vestibular sensation due to hair cell dysfunction are among the most common disabilities. Recent preclinical research demonstrates that treatment of the inner ear with a variety of compounds, including gene therapy agents, may elicit regeneration and/or repair of hair cells in animals exposed to ototoxic medications or other insults to the inner ear. Delivery of gene therapy may also offer a means for treatment of hereditary hearing loss. However, injection of a fluid volume sufficient to deliver an adequate dose of a pharmacologic agent could, in theory, cause inner ear trauma that compromises functional outcome...
June 23, 2017: Journal of the Association for Research in Otolaryngology: JARO
https://www.readbyqxmd.com/read/28609794/-destruction-of-microsurgical-devices-by-sterilisation
#2
Raphaela Berto, Jürgen Strutz
Hospital facilities issue numerous risk announcements on corrosion, deformation or premature wearout of medical devices every year. As there is yet little data on the impact of reprocessing on the quality and durability of microsurgical instruments, this paper aims at evaluating the effects of the reprocessing on microsurgical instruments. Material and Methods 22 brand new microsurgical instruments for stapes surgery were being reprocessed 30 times without being used for surgery or other purposes in the interim time...
June 13, 2017: Laryngo- Rhino- Otologie
https://www.readbyqxmd.com/read/28604579/how-to-avoid-a-learning-curve-in-stapedotomy-a-standardized-surgical-technique
#3
Pingling Kwok, Otto Gleich, Katharina Dalles, Elisabeth Mayr, Peter Jacob, Jürgen Strutz
OBJECTIVE: To evaluate, whether a learning curve for beginners in stapedotomy can be avoided by using a prosthesis with thermal memory-shape attachment in combination with a standardized laser-assisted surgical technique. STUDY DESIGN: Retrospective case review. SETTING: Tertiary referral center. PATIENTS: Fifty-eight ears were operated by three experienced surgeons and compared with a group of 12 cases operated by a beginner in stapedotomy...
June 9, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28601531/sheep-as-a-large-animal-ear-model-middle-ear-ossicular-velocities-and-intracochlear-sound-pressure
#4
Dominik Péus, Ivo Dobrev, Lukas Prochazka, Konrad Thoele, Adrian Dalbert, Andreas Boss, Nicolas Newcomb, Rudolf Probst, Christof Röösli, Jae Hoon Sim, Alexander Huber, Flurin Pfiffner
Animals are frequently used for the development and testing of new hearing devices. Dimensions of the middle ear and cochlea differ significantly between humans and commonly used animals, such as rodents or cats. The sheep cochlea is anatomically more like the human cochlea in size and number of turns. This study investigated the middle-ear ossicular velocities and intracochlear sound pressure (ICSP) in sheep temporal bones, with the aim of characterizing the sheep as an experimental model for implantable hearing devices...
June 7, 2017: Hearing Research
https://www.readbyqxmd.com/read/28598950/drill-induced-cochlear-injury-during-otologic-surgery-intracochlear-pressure-evidence-of-acoustic-trauma
#5
Renee M Banakis Hartl, Jameson K Mattingly, Nathaniel T Greene, Nyssa F Farrell, Samuel P Gubbels, Daniel J Tollin
HYPOTHESIS: Drilling on the incus produces intracochlear pressure changes comparable to pressures created by high-intensity acoustic stimuli. BACKGROUND: New-onset sensorineural hearing loss (SNHL) following mastoid surgery can occur secondary to inadvertent drilling on the ossicular chain. To investigate this, we test the hypothesis that high sound pressure levels are generated when a high-speed drill contacts the incus. METHODS: Human cadaveric heads underwent mastoidectomy, and fiber-optic sensors were placed in scala tympani and vestibuli to measure intracochlear pressures (PIC)...
June 8, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28590999/surgical-management-of-a-persistent-stapedial-artery-a-review
#6
Thadé Pieter Marie Goderie, Waiel Hussain Fadhlallah Alkhateeb, Conrad Frits Smit, Erik Frans Hensen
OBJECTIVE: To evaluate the outcome and per- and postoperative complications of the surgical management of patients with a persistent stapedial artery (PSA). METHODS: A systemic literature search for reports on patients treated for pulsatile tinnitus and/or conductive hearing loss caused by a PSA was conducted of the PubMed and Embase databases using the terms "stapedial" and "artery." Inclusion criteria were adequate description of the intervention and pre- and postoperative signs and symptoms...
July 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28573817/imaging-of-labyrinthine-fistula-after-repair-with-bone-pate
#7
Jeffrey T Vrabec
OBJECTIVES/HYPOTHESIS: To demonstrate imaging of labyrinthine fistula due to cholesteatoma and illustrate outcome following repair with bone pate. STUDY DESIGN: Retrospective review. METHODS: Patients with labyrinthine fistula due to cholesteatoma were identified, and pre- and postoperative imaging was assessed. Method of repair was recorded. The fistula site was examined for patency and bone density after repair. RESULTS: Twenty-nine fistulae were seen in a cohort of 375 cholesteatoma cases (8%)...
June 2, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28570420/semicircular-canal-pressure-changes-during-high-intensity-acoustic-stimulation
#8
Anne K Maxwell, Renee M Banakis Hartl, Nathaniel T Greene, Victor Benichoux, Jameson K Mattingly, Stephen P Cass, Daniel J Tollin
HYPOTHESIS: Acoustic stimulation generates measurable sound pressure levels in the semicircular canals. BACKGROUND: High-intensity acoustic stimuli can cause hearing loss and balance disruptions. To examine the propagation of acoustic stimuli to the vestibular end-organs, we simultaneously measured fluid pressure in the cochlea and semicircular canals during both air- and bone-conducted sound presentation. METHODS: Five full-cephalic human cadaveric heads were prepared bilaterally with a mastoidectomy and extended facial recess...
May 31, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28566723/requirement-for-jagged1-notch2-signaling-in-patterning-the-bones-of-the-mouse-and-human-middle-ear
#9
Camilla S Teng, Hai-Yun Yen, Lindsey Barske, Bea Smith, Juan Llamas, Neil Segil, John Go, Pedro A Sanchez-Lara, Robert E Maxson, J Gage Crump
Whereas Jagged1-Notch2 signaling is known to pattern the sensorineural components of the inner ear, its role in middle ear development has been less clear. We previously reported a role for Jagged-Notch signaling in shaping skeletal elements derived from the first two pharyngeal arches of zebrafish. Here we show a conserved requirement for Jagged1-Notch2 signaling in patterning the stapes and incus middle ear bones derived from the equivalent pharyngeal arches of mammals. Mice lacking Jagged1 or Notch2 in neural crest-derived cells (NCCs) of the pharyngeal arches display a malformed stapes...
May 31, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28561306/stapes-prosthesis-length-and-hearing-outcomes
#10
Qasim Husain, Kenny F Lin, Samuel H Selesnick
OBJECTIVES: First, to determine if prosthesis length plays a role in optimizing successful hearing outcomes in stapedotomy surgery; and second, to determine if patient factors such as height are correlated with prosthesis length. STUDY DESIGN: Retrospective chart review. METHODS: Retrospective chart review of patients undergoing stapedotomy surgeries with adequate follow up. Length of prosthesis, pre-/postoperative audiograms, and follow-up data were obtained...
May 31, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28558458/-clinical-characteristics-in-children-with-cleft-palate-associated-with-middle-ear-cholesteatoma
#11
Y Yang, M Chen, J S Hao, W Liu, J Zhang
Objective: To summarize the characteristics of children diagnosed as cleft palate associated with middle ear cholesteatoma. Methods: There were five middle ear cholesteatoma cases who had previously received cleft palate repairment surgery. All of the patients were followed up for 17 to 47 months. Median follow-up time was 31 months. Results: There were three males and two females with three to eleven years old , and the average of age was seven years and ten months. The time of cleft palate repairment surgery was from six months to four years, and the average age was one year and nine months...
May 7, 2017: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
https://www.readbyqxmd.com/read/28555596/comparative-analysis-of-laser-and-non-laser-stapes-surgeries
#12
Li Jun Du, Hua Gong Gao, Jun Tong, Wen Wen Chen, Liang Shan, Xun Hua Cai
OBJECTIVE: This study aimed to observe differences in the efficacy of laser and surgical treatments of middle-ear conductive hearing loss (MECHL). MATERIALS AND METHODS: A total of 276 ears of 267 patients with MECHL were divided into laser (n=172) and surgical (n=104) treatment groups according to the treatment method. Changes in the air-bone gap (ABG) after treatment and at the time of final follow-up were compared. An ABG value <20 dB was defined as effective and an ABG value <10 dB, significantly effective...
April 2017: Journal of International Advanced Otology
https://www.readbyqxmd.com/read/28555595/endoscopic-vs-microscopic-approach-in-stapes-surgery-advantages-in-the-middle-ear-structures-visualization-and-trainee-s-point-of-view
#13
Giannicola Iannella, Dario Marcotullio, Massimo Re, Alessandra Manno, Benedetta Pasquariello, Diletta Angeletti, Vincenzo Falasca, Giuseppe Magliulo
OBJECTIVE: Comparing the endoscopic and microscopic approaches in stapes surgery, and establishing the surgical approach that allows better results in terms of visualization of the middle ear structures and aids assistant's training. MATERIALS AND METHODS: Twenty-one residents from the first to the fifth year of training in Otolaryngology were enrolled in this prospective study. A questionnaire specifically designed to investigate the understanding of middle ear anatomy, the surgical steps, and a personal opinion about endoscopic stapes surgery was submitted to each resident...
April 2017: Journal of International Advanced Otology
https://www.readbyqxmd.com/read/28549773/cochlear-implantation-in-patients-with-otosclerosis-of-the-otic-capsule
#14
Jay Burmeister, Susan Rathgeb, Jacques Herzog
OBJECTIVE: To evaluate outcomes of cochlear implantation of patients with otosclerosis of the otic capsule. STUDY DESIGN: A retrospective case series of 6 patients (7 ears). PATIENTS: 6 patients (7 ears), 5 patients with severe to profound sensorineural hearing loss; 1 patient with mild to profound sensorineural hearing loss, with radiologic evidence of otosclerosis. All patients were adult males, with or without history of stapes surgery...
May 19, 2017: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/28542633/new-chamber-stapes-prosthesis-a-preliminary-assessment-of-the-functioning-of-the-prototype
#15
Monika Kwacz, Magdalena Sołyga, Maciej Mrówka, Konrad Kamieniecki
Piston-stapedotomy is the most common method for hearing restoration in patients with otosclerosis. In this study, we have experimentally examined a prototype of a new chamber stapes prosthesis. The prototype was implanted in a human cadaver temporal bone. The round window vibrations before and after implantation were measured for the acoustic signal (90 dB SPL, 0.8-8 kHz) in the external auditory canal. In comparison with a 0.4-mm piston prosthesis, the chamber prosthesis induced significantly higher vibration of the round window, especially for frequencies above 1...
2017: PloS One
https://www.readbyqxmd.com/read/28538469/an-assessment-of-the-clinical-acceptability-of-direct-acoustic-cochlear-implantation-for-adults-with-advanced-otosclerosis-in-the-united-kingdom
#16
Pádraig Thomas Kitterick, Guna Reddy-Kolanu, David Baguley, Jeremey Lavy, Peter Monksfield, Rupan Banga, Jaydip Ray, Ad Snik, Gerard M O'Donoghue
HYPOTHESIS: Assess the clinical acceptability of direct acoustic cochlear implantation for patients with advanced otosclerosis and the support for conducting a controlled trial of its effectiveness in the United Kingdom. BACKGROUND: Emerging evidence supports the efficacy of direct acoustic cochlear implantation in patients with advanced otosclerosis whose needs cannot be managed using the combination of stapes surgery and hearing aids. A controlled trial would provide evidence for its effectiveness and cost-effectiveness to healthcare commissioners...
May 22, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28532297/preoperative-assessment-of-stapes-implantations-of-the-vibrant-soundbridge-for-congenital-aural-atresia-patients
#17
Danni Wang, Demin Han, Shouqin Zhao, Ran Ren, Jiyong Dong
OBJECTIVE: The objective of this study is to retrospectively analyze the imaging characteristics of patients with congenital aural atresia who underwent Vibrant Soundbridge implantation, and to investigate the importance of preoperative evaluation of vibroplasty. MATERIALS AND METHODS: The study included 16 patients with bilateral congenital aural atresia aged 6-25 years (mean age, 14.7 years). All patients underwent Vibrant Soundbridge implantations. RESULTS: Among the 16 patients, 15 successfully underwent stapes implantation...
May 22, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28516487/the-petrosal-and-bony-labyrinth-of-diplobune-minor-an-enigmatic-artiodactyla-from-the-oligocene-of-western-europe
#18
Maeva J Orliac, Ricardo Araújo, Fabrice Lihoreau
Anoplotheriinae are Paleogene European artiodactyls that present a unique postcranial morphology with a tridactyl autopodium and uncommon limb orientation. This peculiar morphology led to various hypotheses regarding anoplotheriine locomotion from semiaquatic to partly arboreal or partly bipedal. The petrosal bone, housing the organs of balance, and hearing, offers complementary information to postcranial morphology on the ecology of this uncommon artiodactyl. Here, we investigate the middle ear and bony labyrinth of the small anoplotheriine Diplobune minor based on four specimens from the Early Oligocene locality of Itardies (Quercy, France)...
May 17, 2017: Journal of Morphology
https://www.readbyqxmd.com/read/28508715/data-and-reporting-quality-in-tympanoplasty-and-ossiculoplasty-studies
#19
Susen Lailach, Thomas Zahnert, Marcus Neudert
Objective The objective of our study was to check the documentation of hearing outcome parameters and influencing factors (surgical, pathological, and methodological) in published literature evaluating hearing outcome after tympanoplasty. We aimed to assess how effectively the American Academy of Otolaryngology-Head and Neck Surgery (AAO-HNS) 1995 guidelines were applied. Study Design Retrospective noncontrolled study. Setting Ear research center. Subjects and Methods This study was based on a PubMed research, including peer-reviewed English-speaking original studies published from January 2005 to December 2015...
May 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28498081/finite-element-analysis-of-auditory-characteristics-in-patients-with-middle-ear-diseases
#20
Bo Tu, Xiaoping Li, Zhenhua Nie, Changzheng Shi, Hengguo Li
CONCLUSION: This study validates that a finite element model of the human ossicular chain and tympanic membrane can be used as an effective surgical assessment tool in clinics. OBJECTIVE: The present study was performed to investigate the application of a finite element model of ossicular chain and tympanic membrane for fabrication of individualized artificial ossicles. METHODS: Twenty patients (20 ears) who underwent surgery for middle ear disease (n = 20) and 10 healthy controls (10 ears) were enrolled in the hospital...
July 2017: Acta Oto-laryngologica
keyword
keyword
76942
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"