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https://www.readbyqxmd.com/read/27909837/simultaneous-intracochlear-pressure-measurements-from-two-cochlear-locations-propagation-of-distortion-products-in-gerbil
#1
Wei Dong
Sound energy propagates in the cochlea through a forward-traveling or slow wave supported by the cochlear partition and fluid inertia. Additionally, cochlear models support traveling wave propagation in the reverse direction as the expected mechanism for conveying otoacoustic emissions out of the cochlea. Recently, however, this hypothesis has been questioned, casting doubt on the process by which otoacoustic emissions travel back out through the cochlea. The proposed alternative reverse travel path for emissions is directly through the fluids of the cochlea as a compression pressure in the form of a fast wave...
December 1, 2016: Journal of the Association for Research in Otolaryngology: JARO
https://www.readbyqxmd.com/read/27895001/surgical-management-and-hearing-outcome-of-traumatic-ossicular-injuries
#2
Stefan Delrue, Nicolas Verhaert, Joost van Dinther, Andrzej Zarowski, Thomas Somers, Christian Desloovere, Erwin Offeciers
OBJECTIVE: The purpose of this study was to investigate etiological, clinical, and pathological characteristics of traumatic injuries of the middle ear ossicular chain and to evaluate hearing outcome after surgery. MATERIAL AND METHODS: Thirty consecutive patients (31 ears) with traumatic ossicular injuries operated on between 2004 and 2015 in two tertiary referral otologic centers were retrospectively analyzed. Traumatic events, clinical features, ossicular lesions, treatment procedures, and audiometric results were evaluated...
November 28, 2016: Journal of International Advanced Otology
https://www.readbyqxmd.com/read/27863625/facial-nerve-stimulation-following-cochlear-implantation-for-x-linked-stapes-gusher-syndrome-leading-to-identification-of-a-novel-pou3f4-mutation
#3
Jacob L Wester, Catherine Merna, Kevin A Peng, Rebecca Lewis, Ali R Sepahdari, Gail Ishiyama, Kumiko Hosokawa, Kozo Kumakawa, Akira Ishiyama
We report a case of a nine-year-old male who presented with facial nerve stimulation four years after cochlear implantation. Computed tomography was performed revealing a dilated internal auditory meatus and the cochlear implant electrode was found to be protruding into the fallopian canal at the level of the geniculate ganglion. Subsequent genetic analysis demonstrated X-linked deafness type 2 (DFNX2) caused by a novel c.769C > T nucleotide change in the POU domain, class 3, transcription factor 4 gene (POU3F4)...
December 2016: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/27861302/steerable-robot-assisted-micromanipulation-in-the-middle-ear-preliminary-feasibility-evaluation
#4
Rashid Yasin, Brendan P O'Connell, Haoran Yu, Jacob B Hunter, George B Wanna, Alejandro Rivas, Nabil Simaan
HYPOTHESIS: The use of a robotic manipulator with a dexterously orientable gripper will expand the ability of middle ear surgeons to perform precise tasks and access otherwise challenging anatomic regions. BACKGROUND: Middle ear surgery presents unique challenges because of the constrained operative space and limited access to certain anatomic regions. METHODS: A custom-designed robot with a sideways-reaching gripper was used to evaluate feasibility of manipulation tasks in different middle-ear anatomical zones...
November 17, 2016: Otology & Neurotology
https://www.readbyqxmd.com/read/27855986/human-cochlear-hydrodynamics-a-high-resolution-%C3%AE-ct-based-finite-element-study
#5
Annalisa De Paolis, Hirobumi Watanabe, Jeremy T Nelson, Marom Bikson, Mark Packer, Luis Cardoso
Measurements of perilymph hydrodynamics in the human cochlea are scarce, being mostly limited to the fluid pressure at the basal or apical turn of the scalae vestibuli and tympani. Indeed, measurements of fluid pressure or volumetric flow rate have only been reported in animal models. In this study we imaged the human ear at 6.7 and 3-µm resolution using µCT scanning to produce highly accurate 3D models of the entire ear and particularly the cochlea scalae. We used a contrast agent to better distinguish soft from hard tissues, including the auditory canal, tympanic membrane, malleus, incus, stapes, ligaments, oval and round window, scalae vestibule and tympani...
November 10, 2016: Journal of Biomechanics
https://www.readbyqxmd.com/read/27833873/pre-operative-indicators-of-ossicular-necrosis-in-tubotympanic-csom
#6
Celina Lovely Jayakumar, Leeberk R Inbaraj, George J O Pinto
Ossicular necrosis and erosion is commonly seen in CSOM with cholesteatoma but can also occur in tubotympanic CSOM. This usually comes as a surprise during surgery. Preoperative knowledge of ossicular necrosis helps the surgeon to be better prepared for the surgery and ossicular construction if required. Hence, this study is intended to identify the pre-operative indicators of ossicular necrosis. This cross sectional study was conducted in Father Muller Medical College in Mangalore. Sixty nine consecutive patients with tubotympanic CSOM underwent a detailed clinical examination with pure tone audiometry and subsequently tympanoplasty with or without cortical mastoidectomy...
December 2016: Indian Journal of Otolaryngology and Head and Neck Surgery
https://www.readbyqxmd.com/read/27809939/electrocoagulation-improving-bone-cement-use-in-middle-ear-surgery-short-term-and-middle-term-results
#7
C Galy-Bernadoy, M Akkari, M Mondain, A Uziel, F Venail
BACKGROUND: Bone cement is used for ossicular chain repair and revision stapes surgery. Its efficient use requires cautious removal of mucosa from the ossicles. This paper reports a technique for easy, fast and safe removal of this mucosa prior to cement application. It consists of the application of monopolar electrocoagulation on the ossicles prior to bone cement application. METHODS: The outcomes of six cases of revision stapes surgery and seven cases of partial ossiculoplasty, conducted between 2007 and 2012 using this new technique, were evaluated...
November 4, 2016: Journal of Laryngology and Otology
https://www.readbyqxmd.com/read/27809651/early-functional-results-using-the-nitibond-prosthesis-in-stapes-surgery
#8
Giuseppina Canu, Fulvio Lauretani, Francesca Yoshie Russo, Evelyne Ferrary, Georges Lamas, Olivier Sterkers, Daniele De Seta, Daniele Bernardeschi
CONCLUSION: The NiTiBOND(®) prosthesis allows early results to be obtained similar to those with a manually crimped prosthesis fitted by experienced surgeons, thus reducing the learning curve in this critical step of the procedure. OBJECTIVE: To analyze the 1-month results using the nitinol NiTiBOND(®) prosthesis in primary otosclerosis surgery and to compare the results with those obtained with fully fluoroplastic or fully titanium pistons. MATERIALS AND METHODS: Fifty consecutive cases operated on with the NiTiBOND(®) prosthesis (nitinol group) were compared with 50 cases operated on with a fully fluoroplastic piston (fluoroplastic group), and with 131 cases operated on with a fully titanium piston (first titanium group), and also with 50 cases operated on with the same titanium piston just before using the NiTiBOND(®) piston (last titanium group)...
November 4, 2016: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/27792833/stapes-pyramidal-fixation-by-a-bony-bar
#9
Kai-Chieh Chan
No abstract text is available yet for this article.
October 2016: Ear, Nose, & Throat Journal
https://www.readbyqxmd.com/read/27755451/the-stapes-bar-an-unusual-cause-of-conductive-hearing-loss-with-normal-tympanic-membrane
#10
Denis Ayache, Anis Abdellaoui, Marc Williams, Mary Daval
No abstract text is available yet for this article.
December 2016: Otology & Neurotology
https://www.readbyqxmd.com/read/27752754/visualization-of-anatomy-in-normal-and-pathologic-middle-ears-by-cone-beam-ct
#11
Christian Güldner, Isabell Diogo, Eva Bernd, Stephanie Dräger, Magis Mandapathil, Afshin Teymoortash, Hesham Negm, Thomas Wilhelm
Cone beam computed tomography (CBCT, syn. digital volume tomography = DVT) was introduced into ENT imaging more than 10 years ago. The main focus was on imaging of the paranasal sinuses and traumatology of the mid face. In recent years, it has also been used in imaging of chronic ear diseases (especially in visualizing middle and inner ear implants), but an exact description of the advantages and limitations of visualizing precise anatomy in a relevant number of patients is still missing. The data sets of CBCT imaging of the middle and inner ear of 204 patients were analyzed regarding the visualization of 18 different anatomic structures...
October 17, 2016: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/27749749/a-new-intraoperative-real-time-monitoring-system-for-reconstructive-middle-ear-surgery-an-experimental-and-clinical-feasibility-study
#12
Thomas Zahnert, Marie-Luise Metasch, Hannes Seidler, Matthias Bornitz, Nicoloz Lasurashvili, Marcus Neudert
HYPOTHESIS: Electromagnetical excitation of ossicular vibration is suitable for middle ear transmission measurements in the experimental and clinical setting. Thereby, it can be used as a real-time monitoring system for quality control in ossiculoplasty. BACKGROUND: Positioning and coupling of middle ear prosthesis are a precondition for good postoperative hearing results, but at the same time completely dependent upon the surgeon's subjective judgment during surgery...
December 2016: Otology & Neurotology
https://www.readbyqxmd.com/read/27727526/our-approach-to-revision-stapes-surgery-and-the-outcomes-from-49-procedures-at-a-uk-tertiary-centre
#13
LETTER
H Kanona, M F Bhutta, J Lavy
No abstract text is available yet for this article.
October 11, 2016: Clinical Otolaryngology
https://www.readbyqxmd.com/read/27725177/perilymph-pharmacokinetics-of-locally-applied-gentamicin-in-the-guinea-pig
#14
A N Salt, J J Hartsock, R M Gill, E King, F B Kraus, S K Plontke
Intratympanic gentamicin therapy is widely used clinically to suppress the vestibular symptoms of Meniere's disease. Dosing in humans was empirically established and we still know remarkably little about where gentamicin enters the inner ear, where it reaches in the inner ear and what time course it follows after local applications. In this study, gentamicin was applied to the round window niche as a 20 μL bolus of 40 mg/ml solution. Ten 2 μL samples of perilymph were collected sequentially from the lateral semi-circular canal (LSCC) at times from 1 to 4 h after application...
October 8, 2016: Hearing Research
https://www.readbyqxmd.com/read/27690307/ossicular-bone-damage-and-hearing-loss-in-rheumatoid-arthritis-a-correlated-functional-and-high-resolution-morphometric-study-in-collagen-induced-arthritic-mice
#15
Rensa Chen, Martin Schwander, Mary F Barbe, Marion M Chan
Globally, a body of comparative case-control studies suggests that rheumatoid arthritis (RA) patients are more prone to developing hearing loss (HL). However, experimental evidence that supports this hypothesis is still lacking because the human auditory organ is not readily accessible. The aim of this study was to determine the association between bone damage to the ossicles of the middle ear and HL, using a widely accepted murine model of collagen-induced arthritis (RA mice). Diarthrodial joints in the middle ear were examined with microcomputer tomography (microCT), and hearing function was assessed by auditory brainstem response (ABR)...
2016: PloS One
https://www.readbyqxmd.com/read/27676652/magnetic-resonance-imaging-evaluation-of-endolymphatic-hydrops-andpost-operative-findings-in-cases-with-otosclerosis
#16
Michihiko Sone, Tadao Yoshida, Satofumi Sugimoto, Kyoko Morimoto, Yuriko Okazaki, Masaaki Teranishi, Shinji Naganawa, Tsutomu Nakashima
CONCLUSIONS: The presence of endolymphatic hydrops (EH) in the vestibule on magnetic resonance imaging (MRI) might be a high-risk factor for complications in cases that are candidates for stapes surgery. OBJECTIVE: Pre-operative detection of EH could be valuable in cases that are candidates for stapes surgery to prevent unpredictable complications following surgery. Pre-operative MRI findings and post-operative findings following stapes surgery were compared to evaluate the efficacy of such MRI evaluation for the management of cases with otosclerosis...
September 27, 2016: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/27671643/morphology-and-function-of-neandertal-and-modern-human-ear-ossicles
#17
Alexander Stoessel, Romain David, Philipp Gunz, Tobias Schmidt, Fred Spoor, Jean-Jacques Hublin
The diminutive middle ear ossicles (malleus, incus, stapes) housed in the tympanic cavity of the temporal bone play an important role in audition. The few known ossicles of Neandertals are distinctly different from those of anatomically modern humans (AMHs), despite the close relationship between both human species. Although not mutually exclusive, these differences may affect hearing capacity or could reflect covariation with the surrounding temporal bone. Until now, detailed comparisons were hampered by the small sample of Neandertal ossicles and the unavailability of methods combining analyses of ossicles with surrounding structures...
October 11, 2016: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/27663221/ossiculoplasty-in-chronic-otitis-media-surgical-results-and-prognostic-factors-of-surgical-success
#18
Ana Castro Sousa, Vânia Henriques, Jorge Rodrigues, Rui Fonseca
BACKGROUND AND OBJECTIVES: The goal of ossiculoplasty is to improve hearing. Successful ossiculoplasty depends on several factors. This retrospective study was carried out to analyze hearing results of ossiculoplasty in ears with chronic otitis media (COM) and evaluate clinical outcomes and factors predictive of hearing improvement. SUBJECTS AND METHODS: We reviewed the results of 153 patients with COM (with cholesteatoma (COMC) and without cholesteatoma (COMWC)) who underwent ossiculoplasty between January of 2002 to December of 2011...
September 20, 2016: Acta Otorrinolaringológica Española
https://www.readbyqxmd.com/read/27648330/abnormal-congenital-location-of-stapes-superstructure-clinical-and-embryological-implications
#19
Vânia Henriques, Rafaela Teles, Ana Sousa, Roberto Estevão, Jorge Rodrigues, Alexandra Gomes, Francisco Silva, Ângelo Fernandes, Fausto Fernandes
Congenital middle ear malformations are rare. Most part of them are usually associated with other malformations, such as aural atresia, microtia, and dysmorphic craniofacial features. A clinical case of a 24-year-old male with a right-sided conductive hearing loss since his childhood, without craniofacial malformation, is presented. He was proposed for exploratory tympanotomy under the suspicious diagnosis of otosclerosis. The surgery revealed an abnormal location of stapes' superstructure, which was attached to the promontory and had an isolated and mobile osseous footplate in the oval window...
2016: Case Reports in Otolaryngology
https://www.readbyqxmd.com/read/27642666/the-effect-of-piston-diameter-in-stapedotomy-for-otosclerosis-a-temporal-bone-model
#20
Inge Wegner, Mostafa M A S Eldaebes, Thomas G Landry, Wilko Grolman, Manohar L Bance
HYPOTHESIS: The use of larger-diameter pistons in stapedotomy leads to better hearing outcomes compared with the use of smaller-diameter pistons. There is an interaction between stapes piston diameter and fenestration diameter. BACKGROUND: Otosclerosis can be treated surgically by removing part of the stapes and bypassing the stapes footplate with a prosthesis. Available piston shaft diameters range between 0.3 and 0.8 mm. There has been a tendency toward the use of smaller-diameter pistons, because of a suspected decreased risk of cochlear trauma and subsequent sensorineural hearing loss (SNHL) with smaller pistons...
December 2016: Otology & Neurotology
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