keyword
MENU ▼
Read by QxMD icon Read
search

Topical lidocaine

keyword
https://www.readbyqxmd.com/read/29334290/topical-lidocaine-prilocaine-cream-versus-lidocaine-infiltration-for-pain-relief-during-repair-of-perineal-tears-after-vaginal-delivery-randomized-clinical-trial
#1
Ahmed M Abbas, Hamida A Abdel Hafiz, Aya M Abdelhafez, Armia Michael, Alaa M Ismail
OBJECTIVE: The current study aims to compare the analgesic effect of lidocaine-prilocaine (LP) cream with lidocaine infiltration during repair of perineal tears after vaginal delivery. MATERIALS AND METHODS: A single center open-labeled randomized clinical trial was carried out in a tertiary University Hospital between October 2016 and May 2017 (Clinical Trials.Gov: NCT02883179). We included parous women delivered at gestational age > 37 weeks with first or second degree perineal tears...
January 15, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29287870/postoperative-bradycardia-following-adenotonsillectomy-in-children-does-intraoperative-administration-of-dexmedetomidine-play-a-role
#2
Benjamin Bush, Joseph D Tobias, Chen Lin, James Ruda, Kris R Jatana, Garth Essig, Jennifer Cooper, Dmitry Tumin, Charles A Elmaraghy
INTRODUCTION: Dexmedetomidine is a novel pharmacologic agent that has become a frequently used adjunct during care of pediatric patients with obstructive sleep apnea (OSA) undergoing tonsillectomy. While generally safe and effective, dexmedetomidine is associated with adverse effects of hypotension and bradycardia from its central sympatholytic effects. Due to safety concerns, our institution routinely admits patients with OSA for overnight cardiorespiratory monitoring following tonsillectomy...
January 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29247433/emla-cream-does-not-influence-efficacy-and-pain-reduction-during-pulsed-dye-laser-treatment-of-port-wine-stain-a-prospective-side-by-side-comparison
#3
Wenxin Yu, Tianyou Wang, Jiafang Zhu, Yajing Qiu, Hui Chen, Yunbo Jin, Xi Yang, Xiaojie Hu, Lei Chang, Yijie Chen, Gang Ma, Xiaoxi Lin
EMLA cream was developed to reduce pain during pulsed-dye laser (PDL) treatment; however, no standard assessment for the therapeutic outcomes of PDL with EMLA creams thus far available. This comparative, prospective clinical trial evaluates laser efficacy and pain reduction during PDL treatment with EMLA cream for local topical anesthesia. Nineteen patients with untreated port-wine stain (PWS) were treated using PDL and examined in this study. Treatment specifications included Vbeam® PDL (Candela Corp.), 595-nm wavelength, 9 J/cm2 radiant exposure, 0...
December 15, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/29246893/lid-splinting-eyelid-retraction-technique-a-minimised-sterile-approach-for-intravitreal-injections
#4
Monique Munro, Geoff R Williams, Anna Ells, Michael Fielden, Amin Kherani, Patrick Mitchell, Jessica Ruzicki, Feisal A Adatia
BACKGROUND/AIMS: To describe an alternative technique for avoiding contact with the lids and lashes, without the use of a lid speculum, during intravitreal anti-vascular endothelial growth factor injections. METHODS: Retrospective case series of all patients undergoing intravitreal injections of bevacizumab and ranibizumab, with the lid splinting retraction technique from January 2010 to December 2015. Injections performed by six vitreoretinal specialists were included...
December 15, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/29194091/menthol-reduces-phototoxicity-pain-in-a-mouse-model-of-photodynamic-therapy
#5
Lisa Wright, Daniel Baptista-Hon, Fiona Bull, Faith Dalgaty, Michael Gallacher, Sally H Ibbotson, Tim G Hales
Phototoxicity-induced pain is a major clinical problem triggered by light acting on photosensitising drugs or endogenous porphyrins, notably protoporphyrin IX (PpIX), an intermediary in heme biosynthesis. Protoporphyrin IX accumulates in individuals with erythropoietic protoporphyria and is elevated during photodynamic therapy subsequent to application of 5-aminolevulinic acid (ALA). Pain occurs during irradiation of PpIX and responds poorly to conventional analgesics. Our objective was to develop a model of PpIX phototoxicity pain and investigate the potential of menthol as an analgesic...
November 25, 2017: Pain
https://www.readbyqxmd.com/read/29178034/pharmacotherapy-for-neuropathic-pain-a-review
#6
REVIEW
Diego Fornasari
Neuropathic pain, comprising a range of heterogeneous conditions, is often severe and difficult to manage, and this may result in a chronic condition that negatively affects the overall functioning and quality of life in patients. The pharmacotherapy of neuropathic pain is challenging and for many patients effective treatment is lacking; therefore, evidence-based recommendations are essential. Currently, there is general agreement on which drugs are appropriate for the first-line treatment of neuropathic pain, whereas debate continues regarding second- and third-line treatments...
December 2017: Pain and Therapy
https://www.readbyqxmd.com/read/29160002/a-randomized-double-blind-trial-of-needle-free-injected-lidocaine-versus-topical-anesthesia-for-infant-lumbar-puncture
#7
Ryan Caltagirone, Vidya R Raghavan, Kathleen Adelgais, Genie E Roosevelt
OBJECTIVES: Lumbar punctures (LPs) are commonly performed in febrile infants to evaluate for meningitis, and local anesthesia increases the likelihood of LP success. Traditional methods of local anesthesia require injection which may be painful or topical application which is not effective immediately. Recent advances in needle-free jet injection may offer a rapid alternative to these modalities. We compared a needle-free jet-injection system (J-Tip(™) ) with 1% buffered lidocaine to topical anesthetic (TA) cream for local anesthesia in infant LPs...
November 20, 2017: Academic Emergency Medicine: Official Journal of the Society for Academic Emergency Medicine
https://www.readbyqxmd.com/read/29152749/effect-of-topical-nasal-anesthetic-on-swallowing-in-healthy-adults-a-double-blind-high-resolution-manometry-study
#8
Esther Guiu Hernandez, Kristin Gozdzikowska, Olivia Apperley, Maggie-Lee Huckabee
OBJECTIVE: Topical nasal anesthetic (TNA) is used when evaluating pharyngeal swallowing with high-resolution manometry (HRM). It is unclear if desensitizing the nasal mucosa improves procedure tolerability or affects pharyngeal pressure. This study evaluated the effects of TNA on comfort and pharyngeal pressure using HRM. METHODS: A double-blinded study was conducted with 20 healthy participants ( x¯ = 27 years). Participants performed five saliva and five 10-mL swallows during two exams with ManoScan HRM ESO catheter (Medtronic, Minneapolis, MN) randomized under placebo (nonanesthetic lubricant) and anesthetized (0...
November 20, 2017: Laryngoscope
https://www.readbyqxmd.com/read/29138603/fatal-collapse-due-to-autonomic-dysreflexia-during-manual-self-evacuation-of-bowel-in-a-tetraplegic-patient-living-alone-lessons-to-learn
#9
Subramanian Vaidyanathan, Bakul M Soni, Paul Mansour, Tun Oo
Background: To identify areas for improvement, the National Health Service in England mandates the review of case reports of patients who have died, which should be translated into improved care for other patients. Case report: A 49-year-old Caucasian man sustained C-7 tetraplegia in a motorcycle accident in 1992. In 2009, he developed seizures and collapsed in the lavatory on a number of occasions during manual self-evacuation of his bowel. A 24-hour electrocardiogram recording at that time showed sinus rhythm with a maximum heart rate of 97 and a minimum of 39 beats per minute; there were no significant arrhythmias that could have contributed to his episodes of collapse...
2017: International Medical Case Reports Journal
https://www.readbyqxmd.com/read/29138154/pharmacologic-management-of-chronic-neuropathic-pain-review-of-the-canadian-pain-society-consensus-statement
#10
REVIEW
Alex Mu, Erica Weinberg, Dwight E Moulin, Hance Clarke
OBJECTIVE: To provide family physicians with a practical clinical summary of the Canadian Pain Society (CPS) revised consensus statement on the pharmacologic management of neuropathic pain. QUALITY OF EVIDENCE: A multidisciplinary interest group within the CPS conducted a systematic review of the literature on the current treatments of neuropathic pain in drafting the revised consensus statement. MAIN MESSAGE: Gabapentinoids, tricyclic antidepressants, and serotonin-norepinephrine reuptake inhibitors are the first-line agents for treating neuropathic pain...
November 2017: Canadian Family Physician Médecin de Famille Canadien
https://www.readbyqxmd.com/read/29135709/pilot-study-comparing-topical-anesthetic-agents-in-pterygium-surgery-subconjunctival-injection-versus-2-lidocaine-gel-versus-5-lidocaine-gel
#11
Felipe Pereira, Hélio Francisco Shiroma, Muller Gonçalves Urias, Verônica Haysa Yamada, Acácio Alves de Souza Lima, Ana Luisa Hofling-Lima, Michel Eid Farah, Eduardo Buchele Rodrigues
PURPOSE: To compare the efficacy of different concentrations of topical lidocaine gel with standard subconjunctival anesthesia. METHODS: This was a prospective randomized controlled pilot study with 3 different groups. Group SC received subconjunctival lidocaine and proparacaine drops as needed during surgery. Group L2 received 2% lidocaine gel and group L5 received 5% lidocaine gel. Both lidocaine gel groups could receive another gel dose as needed during the procedure...
November 13, 2017: Cornea
https://www.readbyqxmd.com/read/29125423/management-of-chronic-neuropathic-pain-with-single-and-compounded-topical-analgesics
#12
Nebojsa Nick Knezevic, Tatiana Tverdohleb, Farid Nikibin, Ivana Knezevic, Kenneth D Candido
The goal of our review was to emphasize important aspects that physicians should take into consideration when prescribing topical analgesics as part of chronic neuropathic pain treatment. We discuss the dermatopharmacokinetics and microstructural components of the skin, differences between topical and transdermal drug delivery, and topical medication effects on peripheral neuropathy and central sensitization. Even though the US FDA approved topical analgesics are 8%-capsaicin and 5%-lidocaine patches for treating postherpetic neuralgia, there are many other studies conducted on the efficacy of topical ketamine cream, clonidine gel, topical gabapentin, topical baclofen and topical phenytoin for peripheral neuropathic pain, either alone or in combination with other formulations...
November 2017: Pain Management
https://www.readbyqxmd.com/read/29117658/treatment-of-postherpetic-neuralgia-with-5-topical-lidocaine-plaster-%C3%A2-experience-from-a-small-county-hospital-case-report
#13
Maša Kontić, Višnja Vičić-Hudorović, Narcis Hudorović
Postherpetic neuralgia (PHN) characterized by chronic neuropathic pain is a common complication of herpes zoster. We investigated the efficacy, safety and cost of treating refractory chronic neuropathic pain with 5% topical lidocaine plaster (TLP) in a female patient attending pain unit at a small county hospital. An 80-year-old female diagnosed with PHN presented with severe left intercostal allodynia and hyperalgesia up to the root of the fourth to tenth thoracic dermatome. We administered the well established first- and second-line specific medications for PHN, but treatment regimens were not efficient...
December 2016: Acta Clinica Croatica
https://www.readbyqxmd.com/read/29075099/design-and-evaluation-of-lidocaine-and-prilocaine-coloaded-nanoparticulate-drug-delivery-systems-for-topical-anesthetic-analgesic-therapy-a-comparison-between-solid-lipid-nanoparticles-and-nanostructured-lipid-carriers
#14
Peijun You, Ran Yuan, Chuanyu Chen
PURPOSE: Topical anesthesia analgesic therapy has diverse applicability in solving the barrier properties of skin and unfavorable physicochemical properties of drugs. Lidocaine (LID) combined with prilocaine (PRI) has been used as a topical preparation for dermal anesthesia for treatment of conditions such as paresthesia. MATERIALS AND METHODS: In this study, for combination anesthesia and overcoming the drawbacks of LID and PRI, respectively, LID- and PRI-loaded solid lipid nanoparticles (SLNs) and nanostructured lipid carriers (NLCs) were prepared and characterized by determination of their particle size, drug loading capacity, stability, in vitro drug release behavior and in vitro cellular viability...
2017: Drug Design, Development and Therapy
https://www.readbyqxmd.com/read/29069016/topical-cryoanesthesia-for-the-relief-of-pain-caused-by-steroid-injections-used-to-treat-hypertrophic-scars-and-keloids
#15
RANDOMIZED CONTROLLED TRIAL
Xiuxia Wang, Xiaoli Wu, Ke Liu, Lingling Xia, Xunxun Lin, Wei Liu, Zhen Gao
Intralesional steroid injections are the standard treatment for hypertrophic scars and keloids. The procedure is, however, quite painful and is unpopular with patients because of this. Topical application of anesthetic creams, such as Ametop gel (tetracaine) and EMLA cream (lidocaine and prilocaine), has limited efficacy because of poor drug penetration. The onset of the analgesic effect is also slow, which means that the use of topical anesthetics is time-consuming in clinical practice.We hypothesized that a commercially available cryotip could be used to provide fast-acting topical cryoanesthesia that would reduce the pain associated with steroid injections...
October 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29066862/localized-neuropathic-pain-an-expert-consensus-on-local-treatments
#16
REVIEW
Gisèle Pickering, Elodie Martin, Florence Tiberghien, Claire Delorme, Gérard Mick
BACKGROUND: Pain localization is one of the hallmarks for the choice of first-line treatment in neuropathic pain. This literature review has been conducted to provide an overview of the current knowledge regarding the etiology and pathophysiology of localized neuropathic pain (LNP), its assessment and the existing topical pharmacological treatments. MATERIALS AND METHODS: Literature review was performed using Medline from 2010 to December 2016, and all studies involving LNP and treatments were examined...
2017: Drug Design, Development and Therapy
https://www.readbyqxmd.com/read/29064176/calciphylaxis-after-parathyroidectomy
#17
Sathish Karmegam, Anupkumar Shetty
A 60-year-old African American man with end stage renal disease on hemodialysis (HD) for the past 2.5 years developed severe hyperparathyroidism. Other past medical history included atrial fibrillation, type II diabetes mellitus, hypertension, gout, pericardial effusion needing pericardial window, deep vein thrombosis, mitral insufficiency, and cardiomyopathy with implantable cardioversion device placement. His parathyroid hormone (PTH) level peaked at 4,191 pg/mL despite being on cinacalcet, sevelamer, and paricalcitol...
October 2017: Hemodialysis International
https://www.readbyqxmd.com/read/29062646/calcium-hydroxylapatite-combined-with-microneedling-and-ascorbic-acid-is-effective-for-treating-stretch-marks
#18
Gabriela Casabona, Paula Marchese
BACKGROUND: Stretch marks can have a negative psychological impact on some individuals. Methods are available for treating stretch marks, but high-quality evidence supporting their use is limited. We treat stretch marks using injections of diluted calcium hydroxylapatite (CaHA, Radiesse) filler combined with microneedling and topical ascorbic acid. This retrospective study evaluated the effectiveness of this combined therapy. METHODS: Subjects presented with red (n = 25) or white (n = 10) striae on their buttocks, thighs, knees, abdomen, and breasts...
September 2017: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/29051828/intubation-following-high-dose-rocuronium-in-a-cat-with-protracted-laryngospasm
#19
Graeme M Doodnaught, Daniel Sj Pang
CASE SUMMARY: An 11-year-old spayed female domestic shorthair cat with a history of laryngospasm at induction of general anesthesia presented for dental evaluation and treatment. The cat was premedicated with hydromorphone (0.05 mg/kg) and alfaxalone (0.5 mg/kg) intravenously, pre-oxygenated for 5 mins (3 l/min, face mask) and anesthesia was induced with alfaxalone (to effect) intravenously. Lidocaine (0.1 ml, 2%) was applied topically to the arytenoid cartilages following loss of jaw tone...
July 2017: JFMS Open Reports
https://www.readbyqxmd.com/read/29028074/efficacy-and-safety-of-5-lidocaine-medicated-plasters-in-localized-pain-with-neuropathic-and-or-inflammatory-characteristics-an-observational-real-world-study
#20
F Amato, G Duse, L Consoletti, C Lo Presti, V Firetto, G Ciliberto, L A Parigi, V Palmieri, M Mazza
OBJECTIVE: Based on clinical study results, 5% lidocaine-medicated plaster (5% LMP) is currently recommended for the treatment of localized peripheral neuropathic pain, such as post-herpetic neuralgia (PHN). However, its effective action, as well as the high safety, have indeed led to its use in clinical practice for pain conditions with similar pathophysiological mechanisms. In this study, the efficacy and safety of 5% LMP were investigated in patients with localized pain with neuropathic and/or inflammatory characteristics, such as PHN, post-traumatic/surgical or musculoskeletal pain...
September 2017: European Review for Medical and Pharmacological Sciences
keyword
keyword
7692
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"