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Linda Nash
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2018: Bulletin of the History of Medicine
Balázs Répásy, Dóra Endrei, Antal Zemplényi, István Ágoston, Imre Boncz
INTRODUCTION AND AIM: The aim of our study was to analyse the public price of the montelukast sodium therapy in Hungary. METHOD: Data derived from the nationwide pharmaceutical database of the Hungarian National Health Insurance Fund Administration. We observed the turnover and price of the medicaments containing the active substance montelukast sodium from 2007 to 2015. Accordingly, our indicators were: consumer price, DCT (daily cost of therapy), co-payment, quasi co-payment, DOT (days of treatment)...
April 2018: Orvosi Hetilap
Yan Zhang, Dan-Dan Yu, De-Hua Cui, Xing Liao, Hua Guo
To evaluate the report quality of intervention-related systematic reviews or Meta-analysis published in China Journal of Chinese Materia Medica, we searched CNKI and China Journal of Chinese Materia Medica webpages to collect intervention-related systematic reviews or Meta-analysis since the first issue of the magazine. A total of 40 systematic reviews or Meta-analysis reports were included, including one network Meta-analysis. According to the PRISMA statement published in 2009, the report quality of the systematic reviews or Meta-analysis was evaluated...
March 2018: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
Rui Jin, Kui-Jun Zhao, Gui-Ming Guo, Bing Zhang, Yu-Guang Wang, Chun-Miao Xue, Yi-Heng Yang, Li-Xia Wang, Guo-Hui Li, Jin-Fa Tang, Li-Xing Nie, Xiang-Lin Zhang, Ting-Ting Zhao, Yi Zhang, Can Yan, Suo-Zhong Yuan, Lu-Lu Sun, Xing-Zhong Feng, Dan Yan
With the growth of number of Chinese patent medicines and clinical use, the rational use of Chinese medicine is becoming more and more serious. Due to the complexity of Chinese medicine theory and the uncertainty of clinical application, the prescription review of Chinese patent medicine always relied on experience in their respective, leading to the uncontrolled of clinical rational use. According to the traditional Chinese medicine (TCM) theory and characteristics of the unique clinical therapeutics, based on the practice experience and expertise comments, our paper formed the expert consensus on the prescription review of Chinese traditional patent medicine for promoting the rational use of drugs in Beijing...
March 2018: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
A Krüger-Genge, S Steinbrecht, J-H Küpper, A Lendlein, F Jung
In cancer therapy, a number of drugs with different mechanisms of action are in clinical use, which act directly after administration without metabolism, while others only become active in the metabolites produced in the liver. Such drugs/metabolites - especially when administered parenterally - interact in high concentrations with the endothelium. Whether this induces adverse responses of the endothelial cells (EC) is barely studied for many medicaments.This pilot in vitro study revealed that the addition of cyclophosphamide (CPA) to the culture medium (5 or 10 mM, respectively) showed a clear influence on EC compared to non-treated EC: The number of adherent human vein endothelial cells (HUVEC) decreased by the addition of CPA in a concentration-dependent manner compared to the untreated control, whereby the vitality of adherent cells was not affected...
April 7, 2018: Clinical Hemorheology and Microcirculation
Jing Zhang, Likun Liu, Jing Wang, Baoyin Ren, Lin Zhang, Weiling Li
ETHNOPHARMACOLOGICAL RELEVANCE: Astragalus membranaceus which was originally described in the Shennong's Classic of Materia Medica, the earliest complete Pharmacopoeia of China written from the Warring States Period to Han Dynasty, has been widely used in Chinese medicine for>2,000 years, especially in the prescription of curing cancer. A. membranaceus has various bioactivities, such as anti-tumor, anti-viral, anti-oxidant, anti-diabetes, anti-inflammation, anti-atherosclerosis, immunomodulation, hepatoprotection, hematopoiesis, neuroprotection and so on...
April 13, 2018: Journal of Ethnopharmacology
Zhongzhen Zhao, Ping Guo, Eric Brand
Books that record the sources and applications of medicinal materials are commonly known as bencao ( materia medica ) in China. Bencao ( materia medica ) literature review is the very first step in the standard authentication procedure of Chinese medicinals. As an important part of China's cultural heritage, these various bencao ( materia medica ) texts represent centuries of accumulated wisdom in combating disease and preserving health. In this short review, bencao ( materia medica ) classics of China are broadly divided into three major categories in our routine practice: mainstream bencao ( materia medica ), thematic bencao ( materia medica ) and regional bencao ( materia medica )...
2018: Chinese Medicine
Naveen Virin Goddard, Demetrius Evriviades
Patients that suffer multiple traumatic injuries often present with uncontrollable haemorrhage and rapidly descend into a viscous death triad consisting of hypothermia, coagulopathy and acidosis. Initial surgical intervention does not aim to provide conclusive repair, but instead strives to stop blood loss while priority is given to correct the patient's metabolic state (Duchesne et al., 2010). However in some cases of massive polytrauma, gaining surgical control of bleeding can be incredibly difficult. As a result a number of topical haemostatic agents were developed for use in military and civilian settings...
December 2017: Trauma Case Reports
Pallav Mahesh Patni, Pradeep Jain, Sumeet Jain, Hemalatha Hiremath, Rolly Agarwal, Mona Jain Patni
Treating pathological defects that are caused by resorption in teeth can be challenging. The task is complicated further if the resorption extends beyond the restrains of the root. The aim of this report is to describe a case of extensive internal tunneling resorption (ITR) associated with invasive cervical resorption (ICR) in a maxillary right lateral incisor and its nonsurgical treatment. A 22-year-old male was referred to the department of endodontics with a chief complaint of discolored maxillary right lateral incisor or tooth 12 and a history of trauma...
January 2018: Journal of Conservative Dentistry: JCD
Sherin Jose Chockattu, B S Deepak, K Mallikarjun Goud
Context: One of the important goals of root canal therapy is disinfection aided by irrigation and intracanal medicaments. Commonly used nonsteroidal anti-inflammatory agents have shown anti-bacterial activity, thus, when used as intracanal medicaments, nonantibiotic agents have the potential to provide anti-inflammatory, local analgesic, and anti-bacterial activity. Aim: The aim of this study is to evaluate and compare the anti-bacterial efficiency of anti-inflammatory nonantibiotics ibuprofen and diclofenac, and routinely used intracanal dressing calcium hydroxide (Ca[OH]2 ), against Enterococcus faecalis , in an endodontic model...
January 2018: Journal of Conservative Dentistry: JCD
Fatemeh Kolangi, Zahra Memariani, Mahboubeh Bozorgi, Seyyed Ali Mozaffarpur, Mohaddeseh Mirzapour
BACKGROUND: The increased use of herbal remedies particularly in patients with kidney diseases indicated the importance of studies which focused on nephrotoxic plants. OBJECTIVE: The present study aimed to review and assess the kidney-damaging herbs mentioned in the Persian medicine [PM] books. METHODS: The main PM books were searched for nephrotoxic herbs and their relevant reformers traditionally proposed for preventing renal damage. PubMed, Scopus and Google Scholar were investigated for evaluation of the scientific evidence relating to the nephrotoxicity of herbs...
April 3, 2018: Current Drug Metabolism
Alvaro Mitsunori Nishikawa, Ana Marli Christovam Sartori, Giulia Marcelino Mainardi, Angela Carvalho Freitas, Alexander Itria, Hillegonda Maria Dutilh Novaes, Patrícia Coelho de Soárez
OBJECTIVES: To systematically review the economic evaluations of 23-valent pneumococcal polysaccharide vaccine (PPV23) in adults aged ≥60 years to inform the development of local studies through the discussion of parameters and assumptions that influence the results of the analyses. METHODS: We searched the MEDLINE, Excerpta Medica, Cochrane Library, Latin-American and Caribbean Health Sciences Literature (LILACS), Brazilian Regional Library of Medicine, National Health Service Economic Evaluation, and Centre for Reviews and Dissemination-as well as the Scopus citation index and the Web of Science for full economic evaluations of PPV23 published up to March 2016...
April 2, 2018: Vaccine
E Fazio, A Ferlazzo, S Cristarella, P Medica, G Marino, M Quartuccio
The aim of the present study was to characterize the stress response of donkeys to different semen collection techniques, comparing the physiological patterns of hormonal (adrenocorticotropic hormone: ACTH, cortisol) and biochemical variables (creatinine, total protein, urea, aspartate aminotransferase: AST, alanine aminotransferase: ALT), and routine seminal parameters and sexual behaviour. Twenty two healthy Ragusano donkeys were used and were randomly assigned to one of 2 groups based on different semen collection techniques...
December 2017: Polish Journal of Veterinary Sciences
Ranjana Sharma, Sarika Verma, Shalika Rana, Ajay Rana
Organic acids (OAs) are small non-volatile molecules with widespread usage in processed foods, feeds and instant beverages. The prime aim of this study was to explore major OAs in local citrus fruits ( Citrus limetta , Citrus aurantifolia , Citrus nobilis , Citrus karna , Citrus medica , Citrus ichangensis and Citrus aurantium ) and assessment of their bioactivities. A RP-HPLC-DAD method was developed using buffer free solvent system for rapid detection and quantification of major OAs from citrus fruits and derived products...
April 2018: Journal of Food Science and Technology
Arnaud D Kaze, Jean Joel Bigna, Jobert Richie Nansseu, Jean Jacques Noubiap
INTRODUCTION: Obesity is significant risk factor for venous thromboembolism (VTE); however, the related mechanisms remain unclear. Previous studies have suggested that this might be related to physical factors including anthropometric measures. We intend to conduct a systematic review and meta-analysis of prospective studies to summarise the extant literature on the associations between a set of seven measures of body size and the risk of VTE. METHODS AND ANALYSIS: The current systematic review will include prospective cohort studies assessing the association between seven measures of body size (height, weight, body mass index, waist and hip circumferences, waist-to-hip ratio, waist-to-height ratio) and the risk of VTE...
March 31, 2018: BMJ Open
Ji-Ye Kee, Yo-Han Han, Jeong-Geon Mun, Jae-Young Um, Seung-Heon Hong
ETHNOPHARMACOLOGICAL RELEVANCE: The pharmacological effect derived from herb-herb interaction is important to constitute the prescription especially in traditional oriental medicine. The relationship of two medicinal herbs is called "couplet medicinals" which is used in pair for the purpose of enhancing the therapeutic effect, reducing the toxic effect or the adverse effect. The "Eighteen Incompatible Medicaments" constitute one of the contents in the incompatibility of traditional oriental drugs in a prescription...
March 27, 2018: Journal of Ethnopharmacology
Hina Firdous, Talib Hussain, Monika Singh, Syed Mohd Danish Rizvi, Afrasim Moin, Mohammad A Kamal
Liver ailments including alcoholic liver disease (ALD), still remain the main reason for morbidity & mortality worldwide. In fact, ALD is a multifactorial disease with complex pathophysiology which is linked to several types of liver damages including steatohepatitis, fibrosis and cirrhosis. This review emphasizes on 30 herbal medicinal plants with their extracts studied for protective effect against ALD and current scientific evidence of ALD cure by thirty Indian Materia Medica including Tilia Platyphyllos, Amomum subulatum, Carica papaya, Pogostemon patchouli, Commelina benghalensis, Bacopamonnieri, Pecan nut, Allium cepa, Beta Vulgaris, Adina cordifolia, Ocimum gratissimum, Vernonia amygdalina, Sida veronicaefolia, Chenopodium album, Korean red ginseng, Elephantopus scaber, Tecomella undulata, Prunus armeniaca, Sea tangle (Laminaria japonica), Emblica officinalis, Saccharum officinarum, Cocculus hirsutus, Cassia roxburghii, Zhi-Zi-Da-Huang, Phyllanthus amarus, Aegle marmelos, Agrimonia eupatoria, Flaveria trinervia, Curcuma longa and Garcinia indica...
March 30, 2018: Current Drug Metabolism
Dan-Dan Yu, Yan-Ming Xie, Xing Liao, Ying-Jie Zhi, Jun-Jie Jiang, Wei Chen
To evaluate the methodological quality and reporting quality of randomized controlled trials(RCTs) published in China Journal of Chinese Materia Medica, we searched CNKI and China Journal of Chinese Materia webpage to collect RCTs since the establishment of the magazine. The Cochrane risk of bias assessment tool was used to evaluate the methodological quality of RCTs. The CONSORT 2010 list was adopted as reporting quality evaluating tool. Finally, 184 RCTs were included and evaluated methodologically, of which 97 RCTs were evaluated with reporting quality...
February 2018: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
Jing-Jing Liu, Jin-Ping Si
To clarify the change and development of the original plants, medicinal organs, traditional functions, resource distribution of "Huangjing"(Polygonati Rhizome), a traditional Chinese medicine, we investigated Polygonatum species on the ancient Chinese herbal texts. The name of "Nüwei" was first carried out in the book of Sheng Nong's Herbal Classic. Its effects included two aspects: one was similar to "Weirui"(Polygonati Odorati Rhizome, "Yuzhu"), that was tonifying, nourishing one's vitality, removing wind and dampness, settling five organs, making body lightness, keeping longevity and not being hungry; the second was alike to "Huangjing" recorded in the book of Ming Yi Bie Lu(Appendant Records of Famous Physicians)...
February 2018: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
Chun-Yu Yang, Feng-Qian Guo, Chen Zang, Hui Cao, Bao-Xian Zhang
Ginger juice, a commonly used adjuvant for Chinese materia medica, is applied in processing of multiple Chinese herbal decoction pieces. Because of the raw materials and preparation process of ginger juice, it is difficult to be preserved for a long time, and the dosage of ginger juice in the processing can not be determined base on its content of main compositions. Ginger juice from different sources is hard to achieve consistent effect during the processing of traditional Chinese herbal decoction pieces...
February 2018: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
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