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C de Baat, P G M A Zweers, C van Loveren, A Vissink
Intrinsic tooth discoloration may occur as an adverse effect of fluoride and tetracyclines. Extrinsic tooth discoloration may occur as superficial staining or as discoloration of the superficial pellicle and/or biofilm due to chlorhexidine, liquid iron salts, essential oils, some antibiotics and stannous fluoride. Inhibition of orthodontic tooth movement has been reported due to the use of prostaglandin synthetase inhibitors. If medications or over-the-counter drugs induce hyposalivation or contain much sucrose, caries may develop...
October 2017: Nederlands Tijdschrift Voor Tandheelkunde
Zhao-Zhou Lin, Chan Yang, Bing Xu, Xin-Yuan Shi, Zhi-Qiang Zhang, Jing Fu, Yan-Jiang Qiao
Blending process, which is an essential part of the pharmaceutical preparation, has a direct influence on the homogeneity and stability of solid dosage forms. With the official release of Guidance for Industry PAT, online process analysis techniques have been more and more reported in the applications in blending process, but the research on endpoint detection algorithm is still in the initial stage. By progressively increasing the window size of moving block standard deviation (MBSD), a novel endpoint detection algorithm was proposed to extend the plain MBSD from off-line scenario to online scenario and used to determine the endpoint in the blending process of Chinese medicine dispensing granules...
March 2017: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
Xiao-Na Liu, Qiu-Sheng Zheng, Xiao-Qing Che, Zhi-Sheng Wu, Yan-Jiang Qiao
The blending end-point determination of Angong Niuhuang Wan (AGNH) is a key technology problem. The control strategy based on quality by design (QbD) concept proposes a whole blending end-point determination method, and provides a methodology for blending the Chinese materia medica containing mineral substances. Based on QbD concept, the laser induced breakdown spectroscopy (LIBS) was used to assess the cinnabar, realgar and pearl powder blending of AGNH in a pilot-scale experiment, especially the whole blending end-point in this study...
March 2017: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
Hossein Salehi, Mohammad Mehrasa, Bijan Nasri-Nasrabadi, Mohsen Doostmohammadi, Reihaneh Seyedebrahimi, Navid Davari, Mohammad Rafienia, Mehdi E Hosseinabadi, Maria Agheb, Mansour Siavash
BACKGROUND: Wound healing is a complex biological process. Some injuries lead to chronic nonhealing ulcers, and healing process is a challenge to both the patient and the medical team. We still look forward an appropriate wound dressing. MATERIALS AND METHODS: In this study, starch-based nanocomposite hydrogel scaffolds reinforced by zeolite nanoparticles (nZ) were prepared for wound dressing. In addition, a herbal drug (chamomile extract) was added into the matrix to accelerate healing process...
2017: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
Jinyan Cai, Chao Yang, Tianhong Chen, Lin Zhao
Herba Dendrobii has been documented in the Compendium of Materia Medica, with special efficacy in nourishing Yin and treating diabetes. However, the chemical profile of Dendrobium chrysanthum Lindl. has not been reported yet. The compositions were analysed with UPLC/Q-TOF-MS/MS. 53 compounds were tentatively characterised, and 14 compounds might be new compounds. Some novel lactones of poly-phenylpropanoids were firstly detected, and di-p-hydroxyphenylpropionic acidic p-coumaric acid lactone, a new compound of the first example, was obtained and identified...
October 12, 2017: Natural Product Research
Xiao-Su Miao, Qing-Yu Cui, Zhao-Yi Wang, Xiao-Na Liu, An-Bang Zhao, Yan-Jiang Qiao, Zhi-Sheng Wu
Quality evaluation plays a vital role in ensuring safety and effectiveness of Chinese materia medica (CMM). Microscopic and morphological technologies can be used to distinguish CMM's characteristics, such as shape, size, texture, section, and smell, for authenticity and quality control of CMM. The microscopic and morphological applications of novel micro-technology, colorimeter, and texture analyzer for CMM identification are summarized and the future prospect is discussed in this paper. Various styles and complex sources of CMM are systemically reviewed, including cormophyte medicinal materials, fruit and seeds, pollen grain, and spore materials...
September 2017: Chinese Journal of Natural Medicines
Benjamín Moncada
No abstract text is available yet for this article.
2017: Revista de Investigación Clínica; Organo del Hospital de Enfermedades de la Nutrición
Alejandra Castañón-González, Jaime Javier Cantú-Pompa, Alejandro Miranda-Hernández, Julio César López-Valdés
No abstract text is available yet for this article.
2017: Revista de Investigación Clínica; Organo del Hospital de Enfermedades de la Nutrición
Edgar Santos, Humberto Silos, Arturo Olivares-Rivera, Valente Fragosa Padilla, Renán Sánchez-Porras
No abstract text is available yet for this article.
2017: Revista de Investigación Clínica; Organo del Hospital de Enfermedades de la Nutrición
Verónica Alejandra Gaona-Flores, Luz Arcelia Campos-Navarro, Jesús Arenas-Osuna, Enrique Alcalá-Martínez
Antecedentes: Las estrategias didácticas se han definido como procedimientos, medios o recursos que el docente utiliza para promover el aprendizaje significativo. Objetivo: Identificar las estrategias de enseñanza y de evaluación que utiliza el profesor con residentes en hospitales de tercer nivel de atención médica. Método: Estudio transversal, con profesores de diversas especialidades, en el Centro Médico Nacional La Raza. Se aplicó un cuestionario que valora las estrategias utilizadas en la enseñanza y la evaluación...
2017: Revista de Investigación Clínica; Organo del Hospital de Enfermedades de la Nutrición
Zhong-Yan Zhou, Jia-Qi Xu, Wai-Rong Zhao, Xin-Lin Chen, Yu Jin, Nuo Tang, Jing-Yi Tang
Ferulic acid, a natural ingredient presents in several Chinese Materia Medica such as Radix Angelicae Sinensis, has been identified as an important multifunctional and physiologically active small molecule. However, its pharmacological activity in different blood vessel types and underlying mechanisms are unclear. The present study was to investigate the vascular reactivity and the possible action mechanism of FA on aorta, small mesenteric arteries and coronary arteries isolated from Wistar rats. We found FA dose-dependently relieved the contraction of aorta, small mesenteric arteries and coronary arteries induced by different contractors, U46619, phenylephrine (Phe) and KCl...
October 6, 2017: European Journal of Pharmacology
Wei-Ling Pu, Li-Kang Sun, Xiu-Mei Gao, Curzio Rüegg, Muriel Cuendet, Micheal O Hottiger, Kun Zhou, Lin Miao, Yun-Sha Zhang, Margaret Gebauer
Tumor-associated macrophages (TAMs) play a key role in all stages of tumorigenesis and tumor progression. TAMs secrete different kinds of cytokines, chemokines, and enzymes to affect the progression, metastasis, and resistance to therapy depending on their state of reprogramming. Therapeutic benefit in targeting TAMs suggests that macrophages are attractive targets for cancer treatment. Chinese materia medica (CMM) is an important approach for treating cancer in China and in the Asian region. According to the theory of Chinese medicine (CM) and its practice, some prescriptions of CM regulate the body's internal environment possibly including the remodeling the tumor microenvironment (TME)...
October 2017: Chinese Journal of Integrative Medicine
Lu Zhang, Xiaohua Lu, Jiabo Wang, Pengyan Li, Haotian Li, Shizhang Wei, Xuelin Zhou, Kun Li, Lifu Wang, Ruilin Wang, Yanling Zhao, Xiaohe Xiao
Aconiti Lateralis Radix Praeparata (Fuzi), a type of Chinese materia medica, has been used to treat acute and chronic heart failure (HF) in traditional Chinese medicine and has been proven in numerous animal studies. It is also well-known that Zingiberis Rhizoma (Ganjiang) is ineffective in the treatment of HF, but it can enhance the anti-HF effect of Fuzi. However, the mechanism underlying this compatibility is still not well investigated. To investigate this mechanism, a model of acute heart failure (AHF) in SD rats induced by propafenone hydrochloride was established in this study...
October 5, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
I-Jung Lee, Cheng-Pei Chung, Shu-Jen Chang, Yun-Lian Lin
Eriocauli Flos (Gujingcao; EF), the dried capitulum with the peduncle of Eriocaulon buergerianum Koern. (Eriocaulaceae), is a Chinese herbal medicine for treating eye diseases and inflammation. However, several species of the Eriocaulon genus are used as substitutes in different areas. To examine the species of EF used in Taiwan and to establish the quality control platform, morphological and chemical analyses have been performed. Ten major compounds, including apigenin (7) and its 7-O-β-D-glucopyranoside (1) and 7-O-(6-O-E-coumaroyl)-β-D-glucopyranoside (6), hispidulin (8) and its 7-O-β-D-glucopyranoside (2) and 7-O-(6-O-E-coumaroyl)-β-D-glucopyranoside (5), jaceosidin (9) and its 7-O-β-D-glucopyranoside (3), and toralactone (10) and its 9-O-β-D-glucopyranosyl(1→6)-β-D-glucopyranoside (4), were isolated and identified from commercially available EF...
October 2017: Journal of Food and Drug Analysis
James Jarrett, Alan R White, Sarah L Cresswell, Laurence J Walsh, Roy George
AIMS: The purpose of the present study was to develop techniques to evaluate and quantify the primary components of dental medicament paste mixtures for root canal treatment, and to evaluate if degradation of the primary components occurred during storage. METHODS: The first part of the study developed a mass spectrometry (MS) method for determination of best recovery process. For this process, analytical grades of triamcinolone acetonide, clindamycin HCl, and doxycycline hyclate were sourced and analyzed...
October 7, 2017: Journal of Investigative and Clinical Dentistry
Ana María Ambrosio, Mauricio Andrés Mariani, Andrea Soledad Maiza, Graciela Susana Gamboa, Sebastián Edgardo Fossa, Alejando Javier Bottale
Argentinian hemorrhagic Fever (AHF) is a febrile, acute disease caused by Junín virus (JUNV), a member of the Arenaviridae. Different approaches to obtain an effective antigen to prevent AHF using complete live or inactivated virus, as well as molecular constructs, have reached diverse development stages. This chapter refers to JUNV live attenuated vaccine strain Candid #1, currently used in Argentina to prevent AHF. A general standardized protocol used at Instituto Nacional de Enfermedades Virales Humanas (Pergamino, Pcia...
2018: Methods in Molecular Biology
Venessa Vas, Michael A Akeroyd, Deborah A Hall
A number of assessment tools exist to evaluate the impact of hearing loss, with little consensus among researchers as to either preference or psychometric adequacy. The item content of hearing loss assessment tools should seek to capture the impact of hearing loss on everyday life, but to date no one has synthesized the range of hearing loss complaints from the perspectives of the person with hearing loss and their communication partner. The current review aims to synthesize the evidence on person with hearing loss- and communication partner-reported complaints of hearing loss...
January 2017: Trends in Hearing
S P Hiremath, J Jujjuri, V J Jamakandi
BACKGROUND: Continuous intravenous infusion of controlled drug delivery has certain risks. This could be diligently duplicated devoid of its hassles by using the skin as the port of drug entry. Transdermal drug delivery system is the main route with discrete, self-contained dosage forms when placed on the skin transports the medicament through the skin into the systemic circulation in a well-controlled manner. OBJECTIVE: The rationale of the current work was to formulate and evaluate a transdermal patch of an antihypertensive drug by using different grades of polymers with a view to circumvent the hepatic first pass metabolism and also to escalate its bioavailability...
October 2, 2017: Current Drug Delivery
Minju Song, Yangpei Cao, Su-Jung Shin, Won-Jun Shon, Nadia Chugal, Reuben H Kim, Euiseong Kim, Mo K Kang
INTRODUCTION: Intracanal calcifications have been reported in endodontic cases after revascularization. The purpose of the current study was to determine the incidence of intracanal calcification and potential contributing factors in retrospective revascularization cases. METHODS: Among 37 patients who had undergone revascularization between 2010 and 2014, 29 cases were assessed with average follow-up period of 24.9 months. Clinical and radiographic examinations were performed to evaluate the treatment outcomes, eg, resolution of apical periodontitis (AP), root development, and occurrence of intracanal calcification...
September 28, 2017: Journal of Endodontics
Christelle Nguyen, Isabelle Boutron, Gabriel Baron, Emmanuel Coudeyre, Francis Berenbaum, Serge Poiraudeau, François Rannou
INTRODUCTION: Osteoarthritis (OA) pathophysiology is driven in part by joint inflammation. Resveratrol has in vitro anti-inflammatory properties. We aim to assess the efficacy of oral resveratrol for knee pain at 3 months in people with knee OA. METHODS AND ANALYSIS: We will conduct a randomised double-blind placebo-controlled trial. Overall, 164 individuals with knee OA fulfilling 1986 American College of Rheumatology criteria will be recruited in three tertiary care centres in France and randomised to receive oral resveratrol, 40 mg (two caplets) two times per day for 1 week, then 20 mg (one caplet) two times per day or a matching placebo for a total of 6 months...
September 29, 2017: BMJ Open
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