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https://www.readbyqxmd.com/read/28934562/the-enduring-legacy-of-250-years-of-pharmacology-in-edinburgh
#1
John S Kelly, Angus V P Mackay
Two hundred fifty years ago, the University of Edinburgh appointed Francis Home to the first chair of materia medica, the accumulated knowledge of materials used in healing. Francis Home and his colleagues were determined to improve the quality of medical training in Edinburgh by introducing a final examination and compiling a catalog of medicines validated by the Royal College of Physicians of Edinburgh. The catalog, known as the Edinburgh Pharmacopoeia, was a great success, partly due to the orderly nature of its contents, its routine editing to eliminate worthless entries, and the introduction of new treatments whose preparation was precisely documented...
September 13, 2017: Annual Review of Pharmacology and Toxicology
https://www.readbyqxmd.com/read/28933127/-bencao-literature-investigation-of-polygonum-multiflorum-heshouwu
#2
Li Liang, Jin-Sheng Zheng, Zhong-Zhen Zhao
Heshouwu, derived from the root of Polygonum multiflorum (=Fallopia multiflora), is widely used in the Chinese medicine market as a traditional tonic. The emergence of heshouwu material with a human shape reflects a pursuit of its supplementing effects. However, reports of Heshouwu toxicity have repeatedly surfaced in recent years, attracting widespread concern. To clarify the situation surrounding the safety and efficacy of Heshouwu, this research utilizes a systematic review of the text and illustrations in historical bencao (materia medica) literature to investigate the origin, botanical characteristics, actions and processing of Heshouwu, as well as the origin and historical evolution of Baishouwu ("white Heshouwu")...
December 2016: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/28933081/-recent-advances-of-synthetic-biology-for-production-of-functional-ingredients-in-chinese-materia-medica
#3
Xin-Yao Su, Jian-Ping Xue, Cai-Xia Wang
The functional ingredients in Chinese materia medica are the main active substance for traditional Chinese medicine and most of them are secondary metabolites derivatives. Until now,the main method to obtain those functional ingredients is through direct extraction from the Chinese materia medica. However, the income is very low because of the high extraction costs and the decreased medicinal plants. Synthetic biology technology, as a new and microbial approach, can be able to carry out large-scale production of functional ingredients and greatly ease the shortage of traditional Chinese medicine ingredients...
November 2016: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/28931298/-selective-laser-trabeculoplasty-implication-for-medicament-glaucoma-treatment-interruption-in-pregnant-and-breastfeeding-women
#4
P Výborný, S Sičáková, Z Flórová, I Sováková
During the period of the last six years (2010-2016), the authors performed Selective Laser Trabeculoplasty (SLT) in 32 women (64 eyes); pregnant women patients with primary open angle glaucoma were referred to the Department of Ophthalmology, First Medical Faculty, Charles University, and Central Military Hospital in Prague, Czech Republic, European Union, to perform this procedure with the goal to interrupt their antiglaucomatic treatment by means of eye drops during the pregnancy and the breastfeeding period...
2017: Ceská a Slovenská Oftalmologie
https://www.readbyqxmd.com/read/28930217/influence-of-different-isolation-methods-on-chemical-composition-and-bioactivities-of-the-fruit-peel-oil-of-citrus-medica-l-var-sarcodactylis-noot-swingle
#5
Gang Deng, Jonathan D Craft, Kelly Marie Steinberg, Pei Lei Li, Suraj Kumar Pokharel, William N Setzer
Background: The chemical composition and bioactivities of essential oils (EOs) of fingered citron (Citrus medica L. var. sarcodactylis (Noot.) Swingle) are considerably sensitive and lapsible during high-temperature processing of traditional separating techniques. In the present research, vacuum distillation and ultrafiltration were utilized in order to process the concentrated juice from fingered citron, obtaining a high-quality essential oil. Methods: In order to compare the essential oils obtained by conventional means, the chemical compositions of the essential oils were analyzed using GC-MS, before antimicrobial and antioxidant screening assays were carried out...
January 4, 2017: Medicines (Basel, Switzerland)
https://www.readbyqxmd.com/read/28929676/-understanding-and-development-strategy-of-health-food-containing-chinese-materia-medica
#6
REVIEW
Lin-Yuan Wang, Jian-Jun Zhang, Chun Wang, Jing-Xia Wang, Ying-Li Zhu, Jia Wang, Xue-Min Gao
Health food containing Chinese materia medica (CMM) conforms to the development demands of the age of big health and the theory of preventive treatment. In the view of health care and improvement of resisting diseases, it plays an important role in the market. It is very necessary to have further study and discussion on health food containing CMM. First of all, by comparing, analyzing and summarizing, the health food containing CMM could be defined as the health food which is qualified in security and functionality evaluation, with the traditional Chinese medicines(TCM) within TCM standards as the main raw materials, and the formulation-composition is based on the theory of TCM...
November 2016: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/28929658/-study-on-uplc-fingerprint-of-red-ginseng-based-on-good-separation-and-good-purity-of-chromatographic-peaks
#7
Wei-Hong Feng, Chun Li, Li-Na Ji, Li-Xin Yang, Li-Xin Rong, Liang-Mian Chen, Hong Yi, Zhi-Min Wang
This study is to establish the UPLC fingerprint of red ginseng. The separation was performed on a Waters Acquity BEH C₁₈ column (2.1 mm × 50 mm,1.7 μm), with the mobile phase consisting of acetonitrile and water for gradient elution. The detection wavelength was set at 203 nm. The UPLC fingerprint of red ginseng was established by using sample chromatography of 22 different purchase areas and 26 common peaks were found. Compared with the reference substances, 11 of the common peaks were identified as ginsenosides Rg₁, ginsenoside Re, ginsenoside Rf, ginsenoside Rh₁, ginsenoside Rg₂, ginsenoside Rb₁, 20(S)-ginsenoside F₁, ginsenoside Rb₂, ginsenoside Rb3, 20(S)-ginsenoside Rg₃ and 20(R)-ginsenoside Rg₃, respectively...
October 2016: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/28925170/-analysis-of-projects-funded-by-nsfc-in-field-of-chinese-material-medica-resource-in-recent-three-years
#8
Wei Gao, Shu-Zhen Guo, Li-Wei Han, Feng-Zhu Zhang
The paper reviewed the sponsorship and final reports of projects focus on Science of Chinese materia medica resource in Medical Science Department, National Natural Science Foundation of China. The applicant and supportive organizations were analyzed. The progress and results of some projects were summarized by research fields including formation mechanism of Dao-di herbs, research of plant taxonomy, breeding and cultivation of medical plants, ecological and environmental adaptability of Chinese materia medica resource, quality assessment of Chinese materia medica resource, and biosynthesis and regulation of active compounds...
October 2016: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/28925152/-study-on-botanical-pesticides-and-its-application-in-production-of-traditional-chinese-medicine
#9
REVIEW
Peng Zhang, Xi-Wen Li, Lin-Lin Dong, Shi-Lin Chen
The issues including excessive pesticide residues and heavy metal contamination have become the bottle-neck in the development of Chinese herbal medicines. Compared with traditional chemical pesticides, biological pesticides, especially botanical pesticides, are more safe and environment-friendly, which were beneficial to the quality improvement Chinese medicinal materials. Though there exists a weak basic research and it is hard for promotion and regulation, the policy of good and the desire for botanical pesticides will accelerate its development, and replace traditional chemical pesticides gradually...
October 2016: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/28925139/-rapid-identification-and-evaluation-of-chinese-materia-medica-quality-by-near-infrared-spectroscopy
#10
Gang Bai, Guo-Yu Ding, Yuan-Yuan Hou, Min Jiang, Jie Gao
In recent years, the research object of traditional Chinese medicine(TCM) analysis has not just been limited to the common analysis technology, but focused on the key relationship between chemical ingredients and traditional functions, including Chinese material medica (CMM) attributes, chemical substance and biological function. Near infrared spectroscopy (NIR) analysis technology, due to its unique advantages, has been developed rapidly in the field of pharmaceutical analysis, especially in the TCM analysis...
October 2016: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/28916389/removal-and-killing-of-multispecies-endodontic-biofilms-by-n-acetylcysteine
#11
Young-Suk Choi, Cheul Kim, Ji-Hoi Moon, Jin-Yong Lee
Removal of bacterial biofilm from the root canal system is essential for the management of endodontic disease. Here we evaluated the antibacterial effect of N-acetylcysteine (NAC), a potent antioxidant and mucolytic agent, against mature multispecies endodontic biofilms consisting of Actinomyces naeslundii, Lactobacillus salivarius, Streptococcus mutans and Enterococcus faecalis on sterile human dentin blocks. The biofilms were exposed to NAC (25, 50 and 100mg/mL), saturated calcium hydroxide or 2% chlorhexidine solution for 7 days, then examined by scanning electron microscopy...
September 2, 2017: Brazilian Journal of Microbiology: [publication of the Brazilian Society for Microbiology]
https://www.readbyqxmd.com/read/28914248/comparative-evaluation-of-clinical-and-radiological-success-of-zinc-oxide-ozonated-oil-modified-3mix-mp-antibiotic-paste-and-vitapex-as-treatment-options-in-primary-molars-requiring-pulpectomy-an-in-vivo-study
#12
Divya Doneria, Seema Thakur, Parul Singhal, Deepak Chauhan
OBJECTIVES: The aim of this study was to evaluate the clinical and radiographic success of zinc oxide-ozonated oil (ZnO-OO), modified 3Mix antibiotic paste, and Vitapex in treatment of primary molars requiring pulpectomy. METHODS: Sixty-four primary molars of forty three children aged between 4 and 8 years with pulpally involved primary molars requiring root canal procedures were treated with ZnO-OO, modified 3Mix-MP paste, and Vitapex. The subjects were followed up clinically at 1, 6, and 12 months whereas radiographically at 6 and 12 months, respectively...
October 2017: Journal of the Indian Society of Pedodontics and Preventive Dentistry
https://www.readbyqxmd.com/read/28914245/a-comparative-evaluation-of-clinical-and-radiographic-success-rate-of-pulpotomy-in-primary-molars-using-antioxidant-mix-and-mineral-trioxide-aggregate-an-in-vivo-1-year-follow-up-study
#13
Sommyta Kathal, Shilpi Gupta, Deepak P Bhayya, Ashish Rao, Amrita Pal Roy, Anubhuti Sabhlok
INTRODUCTION: Pulpotomy technique is most widely accepted clinical procedure for treating primary teeth with coronal pulp inflammation caused by caries with no involvement of the radicular pulp. AIM AND OBJECTIVE: The aim of the study was to evaluate the success and efficacy of mineral trioxide aggregate (MTA) and antioxidant mix as pulpotomy agents both clinically and radiographically. MATERIALS AND METHODS: A total of forty primary molars in children aged between 6 and 9 years, requiring for pulpotomy procedures, were selected...
October 2017: Journal of the Indian Society of Pedodontics and Preventive Dentistry
https://www.readbyqxmd.com/read/28901340/sticking-to-principles-and-anticipating-outcomes
#14
Tom Jefferson
Riassunto La pubblicazione di Unanticipated outcomes, la storia personale di Jerome P. Kassirer, ex direttore del New England Journal of Medicine, offre l'opportunità di considerare i principi etici dell'editoria biomedica e scientifica. Il conflitto di interessi, le dichiarazioni e la frode influenzano la credibilità della comunicazione medica, che poggia sulla robustezza e sulla trasparenza dei suoi processi. Non tutto è ancora perduto, ma dobbiamo essere guidati da forti principi morali e da un quadro coerente di valori...
September 2017: Recenti Progressi in Medicina
https://www.readbyqxmd.com/read/28895229/crisis-and-change-the-making-of-a-french-fda
#15
Constance A Nathanson, Henri Bergeron
Policy Points: Introducing a recent special issue of The Lancet on the health system in France, Horton and Ceschia observe that "the dominance of English as the language of science and, increasingly, global health too often closes the door on the history and experiences of others."(1) In that spirit, this manuscript presents a detailed case study of public health policy transformation in France in the early 1990s. It casts light on processes of policy change in a political and cultural environment very different from that of the United States, showing how the public health policy process is shaped by multiple contingencies of history, ideology, and politics...
September 2017: Milbank Quarterly
https://www.readbyqxmd.com/read/28890614/comparison-of-clinical-and-radiographic-success-rates-of-pulpotomy-in-primary-molars-using-ferric-sulfate-and-bioactive-tricalcium-silicate-cement-an-in-vivo-study
#16
Kavita Sirohi, Mohita Marwaha, Anil Gupta, Kalpana Bansal, Ankit Srivastava
INTRODUCTION: Formocresol has been a popular pulpotomy medicament for many years. It is considered the "gold standard" in pediatric dentistry. However, concerns have been raised over its use in children. It has been reported that formocresol has toxic and mutagenic effects in cell culture, dental crypts, and precancerous epithelial cells. Therefore, additional biocompatible treatment alternatives are required to replace formocresol pulpotomy. AIMS: This study compared the clinical and radiographic success rates of ferric sulfate (FS) and bioactive tricalcium silicate cement (Biodentine, Septodont) as pulpotomy agents in primary molar teeth over a period of 9 months...
April 2017: International Journal of Clinical Pediatric Dentistry
https://www.readbyqxmd.com/read/28862688/constituents-of-the-fruits-of-citrus-medica-l-var-sarcodactylis-and-the-effect-of-6-7-dimethoxy-coumarin-on-superoxide-anion-formation-and-elastase-release
#17
Yu-Yi Chan, Tsong-Long Hwang, Ping-Chung Kuo, Hsin-Yi Hung, Tian-Shung Wu
Investigation of the chemical constituents from the fruits of Citrus medica L. var. sarcodactylis Swingle has led to the characterization of a new sesquiterpene 1 along with thirty-two known compounds. The structure of 1 was established on the basis of 2D NMR spectroscopic and mass spectrometric analyses, and the known compounds were identified by comparison of their physical and spectroscopic data with those reported in the literature. In addition, most of the isolated compounds were evaluated for the activity assayed by the in vitro inhibition of superoxide anion generation and elastase release by human neutrophils...
September 1, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28855749/a-cone-beam-computed-tomography-assessment-of-the-efficacy-of-different-irrigation-devices-for-removal-of-silicone-oil-based-calcium-hydroxide-from-root-canal-system
#18
Pradeep Kumar, Ida de Noronha de Ataide, Marina Fernandes, Rajan Lambor
BACKGROUND: Most often used intracanal medicament is calcium hydroxide (Ca(OH)2). Removal of Ca(OH)2 before obturation is mandatory. Different irrigation solutions and devices were tested in the previous study for this purpose. AIM: The aim of this study was to evaluate the comparative efficacy of different irrigation techniques in removing intracanal medicament using cone-beam computed tomography (CBCT). MATERIALS AND METHODS: Cleaning and shaping was carried out in 42 freshly extracted single-rooted mandibular first premolars using Protaper Rotary Files...
March 2017: Journal of Conservative Dentistry: JCD
https://www.readbyqxmd.com/read/28845414/consumption-of-medicaments-in-the-slovak-republic
#19
Pavol Beno, Martin Samohyl
No abstract text is available yet for this article.
July 2017: Iranian Journal of Public Health
https://www.readbyqxmd.com/read/28834697/recommended-standards-for-conducting-and-reporting-ethnopharmacological-field-studies
#20
Caroline S Weckerle, Hugo J de Boer, Rajindra K Puri, Tinde van Andel, Rainer W Bussmann, Marco Leonti
ETHNOPHARMACOLOGICAL RELEVANCE: What are the minimum methodological and conceptual requirements for an ethnopharmacological field study? How can the results of ethnopharmacological field studies be reported so that researchers with different backgrounds can draw on the results and develop new research questions and projects? And how should these field data be presented to get accepted in a scientific journal such as the Journal of Ethnopharmacology? The objective of this commentary is to create a reference that covers the basic standards necessary during planning, conducting and reporting of field research...
August 20, 2017: Journal of Ethnopharmacology
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