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https://www.readbyqxmd.com/read/28331498/electroconvulsive-therapy-use-in-youth-in-the-province-of-quebec
#1
Annie Loiseau, Marie-Claude Harrisson, Vincent Beaudry, Simon Patry
OBJECTIVES: Electroconvulsive therapy's (ECT) safety and tolerability is well-established in the treatment of severe psychiatric disorders in adults, but has been less studied in youth. The aim of the present study was to describe the use of ECT in youth in Quebec City and obtain Child and Adolescent Psychiatrists' (CAP) perceptions in the province of Quebec. METHODS: The authors reviewed charts of minors who received ECT treatment in the Quebec City metropolitan area between 1995 and 2014 (part 1)...
2017: Journal of the Canadian Academy of Child and Adolescent Psychiatry
https://www.readbyqxmd.com/read/28325698/factors-associated-with-antidiabetic-medication-non-adherence-in-patients-with-incident-comorbid-depression
#2
Carlotta Lunghi, Arsène Zongo, Jocelyne Moisan, Jean-Pierre Grégoire, Line Guénette
AIM: To identify factors associated with antidiabetic drug (AD) non-adherence among patients with type 2 diabetes and depression. STUDY DESIGN AND SETTINGS: We conducted a population-based retrospective cohort study among new AD users with a diagnosis of depression following AD initiation. We used public health insurance data from Quebec. The dependent variable was non-adherence (i.e., <90% of days covered by ≥1AD) in the year after a depression diagnosis. Different sociodemographic, clinical and medication-related variables were assessed as potential factors of non-adherence to AD treatment...
March 12, 2017: Journal of Diabetes and its Complications
https://www.readbyqxmd.com/read/28324205/levels-of-intervention-how-are-they-used-in-quebec-hospitals
#3
Marjolaine Frenette, Jocelyne Saint-Arnaud, Karim Serri
In order to promote better practices and communication around end-of-life decision-making, several Canadian hospitals in the province of Quebec have developed a tool called "Levels of Intervention" (LOI). No work to date has been published demonstrating improvement since these forms were implemented. The purpose of the present study was to obtain information about the use of LOI forms across Quebec hospitals and to identify gaps in practice as well as areas for improvement. A retrospective study was undertaken of 299 charts of patients who had died in three Quebec hospitals with a LOI ordered...
March 21, 2017: Journal of Bioethical Inquiry
https://www.readbyqxmd.com/read/28322177/prevalence-estimate-of-cerebral-palsy-in-northern-alberta-births-2008-2010
#4
Charlene M T Robertson, M Florencia Ricci, Kathleen O'Grady, Maryam Oskoui, Helly Goez, Jerome Y Yager, John C Andersen
OBJECTIVES: The objectives of this study were to determine prevalence estimates of cerebral palsy (CP) among 5-year-old children in northern Alberta; to provide congenital, gestational age- and birth weight-specific, and postneonatal CP rates; and to describe motor subtypes and function. METHODS: This population-based prevalence estimate study, part of the Canadian Cerebral Palsy Registry, reports confirmed CP diagnoses at age 5 years made by pediatric rehabilitation and child neurology specialists...
March 21, 2017: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
https://www.readbyqxmd.com/read/28315666/feasibility-and-safety-of-a-powered-exoskeleton-for-assisted-walking-for-persons-with-multiple-sclerosis-a-single-group-preliminary-study
#5
Allan J Kozlowski, Michelle Fabian, Dipan Lad, Andrew Delgado
OBJECTIVE: To examine the feasibility, safety, and secondary benefit potential of exoskeleton-assisted walking with one device for persons with multiple sclerosis (MS) DESIGN: Single-group longitudinal preliminary study with 8-week baseline, 8-week intervention, and 4-week follow-up. SETTING: Outpatient MS clinic at tertiary care hospital. PARTICIPANTS: The 13 participants were mostly female who ranged in age from 38-62 years and on Expanded Disability Status Scale scores from 5...
March 15, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28301587/the-duplication-mutation-of-quebec-platelet-disorder-dysregulates-plau-but-not-c10orf55-selectively-increasing-production-of-normal-plau-transcripts-by-megakaryocytes-but-not-granulocytes
#6
Catherine P M Hayward, Minggao Liang, Subia Tasneem, Asim Soomro, John S Waye, Andrew D Paterson, Georges E Rivard, Michael D Wilson
Quebec Platelet disorder (QPD) is a unique bleeding disorder that markedly increases urokinase plasminogen activator (uPA) in megakaryocytes and platelets but not in plasma or urine. The cause is tandem duplication of a 78 kb region of chromosome 10 containing PLAU (the uPA gene) and C10orf55, a gene of unknown function. QPD increases uPA in platelets and megakaryocytes >100 fold, far more than expected for a gene duplication. To investigate the tissue-specific effect that PLAU duplication has on gene expression and transcript structure in QPD, we tested if QPD leads to: 1) overexpression of normal or unique PLAU transcripts; 2) increased uPA in leukocytes; 3) altered levels of C10orf55 mRNA and/or protein in megakaryocytes and leukocytes; and 4) global changes in megakaryocyte gene expression...
2017: PloS One
https://www.readbyqxmd.com/read/28301049/determining-the-rate-of-underrecognition-of-west-nile-virus-neurologic-disease-in-the-province-of-quebec-in-2012
#7
Gilles Delage, Sophie Dubuc, Yves Grégoire, Anne-Marie Lowe, France Bernier, Marc Germain
BACKGROUND: During a major outbreak of West Nile virus (WNV) infection in the province of Quebec in 2012, public health authorities (PHAs) suspected underrecognition of West Nile neurologic disease (WNND). With data on acute infections detected in blood donors, an estimate of the degree of underrecognition was produced. STUDY DESIGN AND METHODS: All 2012 donors were tested for WNV infection with the use of reverse transcription-polymerase chain reaction (RT-PCR)...
March 16, 2017: Transfusion
https://www.readbyqxmd.com/read/28286711/taxonomic-and-functional-trait-diversity-of-wild-bees-in-different-urban-settings
#8
Étienne Normandin, Nicolas J Vereecken, Christopher M Buddle, Valérie Fournier
Urbanization is one of the major anthropogenic processes contributing to local habitat loss and extirpation of numerous species, including wild bees, the most widespread pollinators. Little is known about the mechanisms through which urbanization impacts wild bee communities, or the types of urban green spaces that best promote their conservation in cities. The main objective of this study was to describe and compare wild bee community diversity, structure, and dynamics in two Canadian cities, Montreal and Quebec City...
2017: PeerJ
https://www.readbyqxmd.com/read/28282104/retrospective-analysis-of-emerging-drugs-use-in-a-quebec-women-s-and-children-s-university-hospital-and-perspectives-for-safe-and-optimal-drug-use
#9
Jennifer Corny, Elaine Pelletier, Denis Lebel, Jean-François Bussières
BACKGROUND: Only few medicines are licensed for children. The use of emerging drugs (unmarketed drug, off-label drug with poorly documented use, and/or costly drugs) might represent an essential alternative for pediatric patients. OBJECTIVES: The objective of the study was to assess emerging drug uses rate and profile in our women's and children's centre to support the implementation of an appropriate policy. METHODS: We identified retrospectively emerging drugs used between 2013-01-01 and 2014-02-28, using computerized pharmacist software extraction of drugs used...
March 10, 2017: Journal of Population Therapeutics and Clinical Pharmacology
https://www.readbyqxmd.com/read/28270034/inuit-interpreters-engaged-in-end-of-life-care-in-nunavik-northern-quebec
#10
Shawn Renee Hordyk, Mary Ellen Macdonald, Paul Brassard
BACKGROUND: Inuit interpreters are key players in end-of-life (EOL) care for Nunavik patients and families. This emotionally intensive work requires expertise in French, English and Inuit dialects to negotiate linguistic and cultural challenges. Cultural differences among medical institutions and Inuit communities can lead to value conflicts and moral dilemmas as interpreters navigate how best to transmit messages of care at EOL. OBJECTIVES: Our goal was to understand the experience of Inuit interpreters in the context of EOL care in Nunavik in order to identify training needs...
2017: International Journal of Circumpolar Health
https://www.readbyqxmd.com/read/28268205/consumer-preferences-for-pork-chops-in-five-canadian-provinces
#11
T M Ngapo
The aim of this study is to identify the most important characteristics of fresh pork that determine consumer choice in five Canadian provinces. Within-consumer preference replication and systematic image manipulation in surveying showed differences in strategies for pork choice in lean colour (P<0.001) and marbling (P=0.006). High proportions of Nova Scotians (29%) chose light red pork, Albertans (42%) dark red and Quebecers (29%) non-marbled pork. Overall, the most important choice criteria were fat cover (57% preferred lean, 8% fatty) and lean colour (35% dark red, 18% light red)...
February 27, 2017: Meat Science
https://www.readbyqxmd.com/read/28259313/limited-evidence-suggests-tooth-loss-is-associated-with-increased-risk-of-cognitive-impairment
#12
Elizabeth Krall Kaye
ARTICLE TITLE AND BIBLIOGRAPHIC INFORMATION: Tooth loss increases the risk of diminished cognitive function: a systematic review and meta-analysis. Cerutti-Kopplin D, Feine J, Padilha DM, et al. JDR Clin Translational Res 2016;1(1):10-9. SOURCE OF FUNDING: Government. Dr Cerutti-Kopplin received a scholarship for the Coordenaçao de Aperfeiçoamento de Pessoal de Nível Superior, Brazil; Dr Booij received a new investigator award from the Canadian Institutes of Health Research; and Dr Emami holds a Canadian Institutes of Health Research Clinician Science Award and new investigator funds from the Fonds de Recherche du Québec-Santé TYPE OF STUDY/DESIGN: Systematic review with meta-analysis of data...
March 2017: Journal of Evidence-based Dental Practice
https://www.readbyqxmd.com/read/28252379/are-inequalities-produced-through-the-differential-access-to-play-opportunities-at-school-a-call-to-level-the-playing-field
#13
Stephanie A Alexander, Tracie A Barnett, Caroline Fitzpatrick
Children's play is characterized as pleasurable, but it is also viewed as critical for child health and well-being. Yet over the past decade, play researchers and advocates from various disciplines have suggested that there are decreasing opportunities for children to play, particularly at school. One concern is that the changing play environment in schools is reducing children's active play options and is thereby contributing to increases in childhood obesity. Building on findings from the QUébec Adipose and Lifestyle InvesTigation in Youth (QUALITY), this commentary suggests that while opportunities to engage in physical activity may indeed be differentially shaped by school play environments, physical health may not be the only factor at stake in unequal play environments in schools...
March 1, 2017: Canadian Journal of Public Health. Revue Canadienne de Santé Publique
https://www.readbyqxmd.com/read/28252368/consumption-of-energy-drinks-among-qu%C3%A3-bec-college-students
#14
Marianne Picard-Masson, Julie Loslier, Pierre Paquin, Karine Bertrand
OBJECTIVES: Consumption of energy drinks (ED) raises concerns because of adverse health effects possibly linked with high levels of caffeine and sugar intake. The study looks at the scope of ED consumption as well as some of the associated characteristics. METHODS: Thirty-six public colleges in the Canadian province of Québec agreed to participate in a descriptive cross-sectional study (n = 36). In February 2013, participating colleges invited their students to answer an online questionnaire on consumption of ED, alcoholic ED (AED), and ED in combination with other psychotropic drugs...
March 1, 2017: Canadian Journal of Public Health. Revue Canadienne de Santé Publique
https://www.readbyqxmd.com/read/28248890/effect-of-contraindicated-drugs-for-heart-failure-on-hospitalization-among-seniors-with-heart-failure-a-nested-case-control-study
#15
Catherine Girouard, Jean-Pierre Grégoire, Paul Poirier, Jocelyne Moisan
Little is known about the effect of nonsteroidal anti-inflammatory drugs (NSAIDs), thiazolidinediones (TZDs), nifedipine and nondihydropyridine calcium channel blockers (CCBs) usage on the risk of all-cause hospitalization among seniors with heart failure (HF). We assessed the risk of all-cause hospitalization associated with exposure to each of these drug classes, in a population of seniors with HF.Using the Quebec provincial databases, we conducted a nested case-control study in a population of individuals aged ≥65 with a first HF diagnosis between 2000 and 2009...
March 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28246412/conceptualization-of-convenience-euthanasia-as-an-ethical-dilemma-for-veterinarians-in-quebec
#16
Dominick Rathwell-Deault, Béatrice Godard, Diane Frank, Béatrice Doizé
Companion animal welfare in our society has become increasingly important, yet many healthy animals are euthanized in veterinary facilities. How is it possible to explain the simultaneous presence of these opposing views of obligation toward animals? The goal of this study was to describe convenience euthanasia of companion animals as experienced by veterinarians in order to understand their thought processes. A qualitative study was undertaken to analyze the results of interviews of 14 veterinarians. The study showed that veterinarians interviewed assessed convenience euthanasia based mainly on their subjective evaluation of the owner-animal bond...
March 2017: Canadian Veterinary Journal. la Revue Vétérinaire Canadienne
https://www.readbyqxmd.com/read/28242499/the-interaction-of-gsk3b-and-fxr1-genotypes-may-influence-the-mania-and-depression-dimensions-in-mood-disorders
#17
Alexandre Bureau, Jean Martin Beaulieu, Thomas Paccalet, Yvon C Chagnon, Michel Maziade
BACKGROUND: Previous evidence in healthy subjects suggested that functional polymorphisms GSK3B rs12630592 and FXR1 rs496250 interact in regulating mood and emotional processing. We attempted to replicate this interaction primarily on manic and depressive dimensions in mood disorder patients, and secondarily on schizophrenia patients, diagnosis itself and age of onset. METHODS: Symptom dimensions were derived from the Comprehensive Assessment of Symptoms and History 82 items rated lifetime in acute episodes and stabilized interepisode intervals in 384 patients from the Schizophrenia and Bipolar Disorder Eastern Quebec Kindred Study...
February 16, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28240576/open-reduction-with-internal-fixation-of-mandibular-angle-fractures-a-retrospective-study
#18
Carl Bouchard, Masoud Mansouri
OBJECTIVE: The goal of this project was to report the complications associated with mandibular angle fractures and identify variables affecting their occurrence. METHODS: We retrospectively reviewed the charts of patients with a mandibular angle fracture treated at the Centre hospitalier universitaire de Québec between 2009 and 2013. RESULTS: Seventy-eight patients (73 males) aged 15-59 years (mean 25.2 years) met our inclusion criteria. A wisdom tooth was present in 85...
January 2017: Journal—Canadian Dental Association, Journal de L'Association Dentaire Canadienne
https://www.readbyqxmd.com/read/28237527/a-survey-of-pharmacists-knowledge-and-views-of-biosimilars-in-quebec-and-france
#19
A Adé, O Bourdon, J-F Bussières
OBJECTIVE: The objective of this study was to survey pharmacists' knowledge and views of biosimilars in Quebec and France. METHODS: An online and anonymous survey was conducted. The survey was divided into two parts including: (1) ten multiple choice questions on main characteristics that distinguish biosimilars from generic drugs; (2) fifteen statements on biosimilars key issues (interchangeability, immunogenicity risk management…). Pharmacists were asked to indicate their level of agreement to these statements using a 5-item Likert scale...
February 22, 2017: Annales Pharmaceutiques Françaises
https://www.readbyqxmd.com/read/28229246/psychological-well-being-as-a-predictor-of-casual-sex-relationships-and-experiences-among-adolescents-a-short-term-prospective-study
#20
Sophie Dubé, Francine Lavoie, Martin Blais, Martine Hébert
Psychological characteristics may predispose youths to engage in casual sex relationships and experiences (CSREs). Using a prospective longitudinal design and in a subsample of 2601 high school students in the province of Québec, we explored possible shifts in engaging in one-night stands (ONSs) and friends with benefits (FWB) relationships over a 6-month period among sexually active adolescents. We also examined the relationships among well-being predictors (psychological distress, self-esteem, suicidal ideation, and alcohol and drug consumption) and these shifts while exploring possible gender differences...
February 22, 2017: Archives of Sexual Behavior
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