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https://www.readbyqxmd.com/read/28446419/the-smartphone-peer-physical-activity-counseling-sppac-program-for-manual-wheelchair-users-protocol-of-a-pilot-randomized-controlled-trial
#1
Krista L Best, François Routhier, Shane N Sweet, Kelly P Arbour-Nicitopoulos, Jaimie F Borisoff, Luc Noreau, Kathleen A Martin Ginis
BACKGROUND: Physical activity (PA) must be performed regularly to accrue health benefits. However, the majority of manual wheelchair users do not meet PA recommendations. Existing community-based PA programs for manual wheelchair users appear to work, but effect sizes are small and retention is low. Existing PA programs may not fully implement some psychosocial factors that are strongly linked with PA (eg, autonomy). The use of peers and mobile phone technology in the Smartphone Peer PA Counseling (SPPAC) program represents a novel approach to cultivating a PA-supportive environment for manual wheelchair users...
April 26, 2017: JMIR Research Protocols
https://www.readbyqxmd.com/read/28444846/forensic-analysis-of-latent-fingermarks-by-silver-assisted-ldi-imaging-ms-on-non-conductive-surfaces
#2
Nidia Lauzon, Martin Dufresne, Alexandre Beaudoin, Pierre Chaurand
Silver-assisted laser desorption ionization (AgLDI) imaging mass spectrometry (IMS) has been demonstrated to be a useful technology for fingermark analysis allowing for the detection of several classes of endogenous as well as exogenous compounds. Ideally, in IMS analyses, the fingermarks are deposited under controlled conditions on metallized conductive target slides. However, in forensic investigations, fingermarks are often found on a variety of non-conductive surfaces. A sputtered silver layer renders the target surface conductive, which allows the analyses of insulating surfaces by time-of-flight (TOF) IMS...
April 26, 2017: Journal of Mass Spectrometry: JMS
https://www.readbyqxmd.com/read/28443266/cost-effectiveness-of-palivizumab-compared-to-no-prophylaxis-in-term-infants-residing-in-the-canadian-arctic
#3
Anna Banerji, Kaspar Ng, Theo J Moraes, Vladimir Panzov, Joan Robinson, Bonita E Lee
BACKGROUND: Hospital admissions for respiratory syncytial virus infection result in large health expenditures for Inuit infants. Palivizumab has been shown to be highly effective in reducing such admissions in preterm Inuit infants. We performed a cost-effectiveness analysis estimating the incremental cost-effectiveness ratio (ICER) for palivizumab prophylaxis per admission related to respiratory syncytial virus avoided in healthy term infants across the Canadian Arctic. METHODS: We compared universal palivizumab prophylaxis in term infants less than 6 months of age to no prophylaxis in 8 Arctic regions: the Northwest Territories, Nunavut, Nunavut without Iqaluit, the 3 subregions of Nunavut (Kitikmeot, Kivalliq and Qikiqtaaluk), the Qikiqtaaluk Region without Iqaluit, and Nunavik (northern Quebec)...
October 2016: CMAJ Open
https://www.readbyqxmd.com/read/28438951/team-based-versus-traditional-primary-care-models-and-short-term-outcomes-after-hospital-discharge
#4
Bruno D Riverin, Patricia Li, Ashley I Naimi, Erin Strumpf
BACKGROUND: Strategies to reduce hospital readmission have been studied mainly at the local level. We assessed associations between population-wide policies supporting team-based primary care delivery models and short-term outcomes after hospital discharge. METHODS: We extracted claims data on hospital admissions for any cause from 2002 to 2009 in the province of Quebec. We included older or chronically ill patients enrolled in team-based or traditional primary care practices...
April 24, 2017: CMAJ: Canadian Medical Association Journal, Journal de L'Association Medicale Canadienne
https://www.readbyqxmd.com/read/28427300/object-decision-test-borb-normative-data-for-the-adult-quebec-population-and-performance-in-alzheimer-s-disease-and-the-semantic-variant-of-primary-progressive-aphasia
#5
Alexandre St-Hilaire, Marie-Claude Blackburn, Maximiliano A Wilson, Robert Jr Laforce, Carol Hudon, Joël Macoir
Object decision (OD) test is one subtest of the Birmingham Object Recognition Battery (BORB). It is useful for differential diagnosis among several neurodegenerative diseases. However, normative data provided with this battery count on very few subjects and do not control for the effect of age, which limits interpretability. The purpose of Study 1 was to provide normative data for the OD test of the BORB (version A-hard). The objectives of Study 2 were to establish the diagnostic validity of this task and predictive validity of the normative data in the case of the semantic variant of primary progressive aphasia (svPPA) and Alzheimer's disease (AD)...
April 21, 2017: Neuropsychology, Development, and Cognition. Section B, Aging, Neuropsychology and Cognition
https://www.readbyqxmd.com/read/28425216/pneumonia-risk-in-asthma-patients-using-inhaled-corticosteroids-a-quasi-cohort-study
#6
Christina J Qian, Janie Coulombe, Samy Suissa, Pierre Ernst
AIM: Studies have linked the use of inhaled corticosteroids (ICS) to excess pneumonia risk in COPD patients. The risk in asthma patients remains unclear. The objective was to examine the risk of pneumonia with ICS in patients 12 to 35 years old with asthma. METHODS: We formed a cohort of asthma patients treated from 1990-2007 using Quebec health insurance databases. Subjects were considered currently exposed if they had an ICS dispensed within the 60 days prior to their pneumonia index event or matched person-moment...
March 28, 2017: British Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/28416901/mechanical-efficiency-in-children-with-different-body-weight-a-longitudinal-assessment-of-the-quality-cohort
#7
G Jabbour, A Tremblay, M Henderson, M-E Mathieu
Net mechanical efficiency (MEnet), which reflects the body's ability to transfer energy above resting levels in external work, is similar in young children regardless of their body weights. However, it is unclear whether MEnet remains stable during growth and maturation. We sought to determine whether net mechanical efficiency (MEnet) changes over a period of 3 years in children and to identify the factors associated with possible changes. A total of 169 children participating in the QUALITY (Quebec Adipose and Lifestyle InvesTigation in Youth) cohort completed an incremental cycling test, resulting in the same maximal power output during both visits...
March 2017: Biology of Sport
https://www.readbyqxmd.com/read/28412641/the-gap-between-entitlement-and-access-to-healthcare-an-analysis-of-candidacy-in-the-help-seeking-trajectories-of-asylum-seekers-in-montreal
#8
Liana E Chase, Janet Cleveland, Jesse Beatson, Cécile Rousseau
In 2012 the Canadian government made significant cuts to its historically strong federal refugee health coverage plan. While this policy had negligible effects on the level of coverage provided to asylum seekers in Quebec, there is evidence that this group nonetheless experienced reduced healthcare access during the period of polarized national debate that ensued. This study engaged the "candidacy" model of healthcare access to illuminate factors contributing to the observed gap between entitlement and access...
March 21, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28404721/family-medicine-residents-training-in-knowledge-about-and-perceptions-of-digital-rectal-examination
#9
Annick Bussières, Alexandre Bouchard, David Simonyan, Sebastien Drolet
OBJECTIVE: To evaluate family medicine residents' training in, knowledge about, and perceptions of digital rectal examination (DRE). DESIGN: Descriptive study, using an online survey that was available in French and English. SETTING: Quebec. PARTICIPANTS: A total of 217 residents enrolled in a family medicine program. MAIN OUTCOME MEASURES: Residents' demographic characteristics; the DRE teaching they received throughout their medical training; their reasons for omitting DRE; their recognition of DRE indications (strong vs weak) and application of DRE for 10 anorectal complaints; and their perceptions of the overall quality of the DRE training they received...
April 2017: Canadian Family Physician Médecin de Famille Canadien
https://www.readbyqxmd.com/read/28401143/impact-of-abiraterone-acetate-with-and-without-prior-docetaxel-chemotherapy-on-the-survival-of-patients-with-metastatic-castration-resistant-prostate-cancer-a-population-based-study
#10
Joice Rocha, Armen G Aprikian, Marie Vanhuyse, Fabio L Cury, Jason Hu, Noémie Prévost, Alice Dragomir
BACKGROUND: Abiraterone acetate was introduced in Quebec in 2012 for the treatment of metastatic castration-resistant prostate cancer (mCRPC) in patients who had received chemotherapy with docetaxel. This study describes abiraterone use in the early postapproval period and its clinical effectiveness in Quebec, for both patients who had received docetaxel chemotherapy and those who could not receive docetaxel therapy owing to medical reasons. METHODS: A retrospective cohort study was conducted using Quebec public health care administrative databases...
January 2017: CMAJ Open
https://www.readbyqxmd.com/read/28401126/factors-associated-with-the-duration-of-disability-benefits-claims-among-canadian-workers-a-retrospective-cohort-study
#11
Sohail M Mulla, Sun Makosso-Kallyth, Nathalie St-Hilaire, Katrena Munsch, Peter B Gove, Diane Heels-Ansdell, Gordon H Guyatt, Jason W Busse
BACKGROUND: Disability insurance protects workers from total loss of income in case of a disabling injury or illness by providing wage-replacement benefits. To better inform early identification of claims at risk of prolonged recovery, we explored predictors of the duration of disability benefits claims. METHODS: We conducted a retrospective cohort study using claims data provided by SSQ Life Insurance Company Inc., a private Canadian disability insurer. We examined all claims SSQ approved for short- and long-term disability benefits from Jan...
January 2017: CMAJ Open
https://www.readbyqxmd.com/read/28398706/can-we-rely-on-pharmacy-claims-databases-to-ascertain-maternal-use-of-medications-during-pregnancy
#12
Jin-Ping Zhao, Odile Sheehy, Jessica Gorgui, Anick Bérard
BACKGROUND: Administrative databases are increasingly used to measure drug exposure in perinatal pharmacoepidemiology. We aimed to estimate the concordance between records of prescriptions filled in pharmacies and self-reported drug use during pregnancy. METHODS: Data on self-reported medication use were collected at each trimester of pregnancy among a sub-sample from the Organization of Teratology Information Specialists Antidepressants in Pregnancy Cohort. Women were eligible if they were Quebec resident and provided their pharmacist's contact information...
April 3, 2017: Birth Defects Res
https://www.readbyqxmd.com/read/28395236/risk-aversion-and-willingness-to-pay-for-water-quality-the-case-of-non-farm-rural-residents
#13
Bruno Larue, Gale E West, Alphonse Singbo, Lota Dabio Tamini
Stated choice experiments are used to investigate the economic valuation of rural residents living in the province of Quebec for water quality improvements. In Quebec, rural residents played an important role in the setting of stricter environmental regulations. Unlike most stated choice experiments about the valuation of improvements in water quality, this study explicitly accounts for risk in the design and analysis of choice experiments. Risk in phosphorus and coliform reductions is introduced through a three-point uniform distribution in the choice sets...
April 7, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28391911/predicting-proprotein-convertase-subtilisin-kexin-type-9-loss-of-function-mutations-using-plasma-pcsk9-concentration
#14
Eric Wanneh, Grisel Luna, Robert Dufour, Alexis Baass
BACKGROUND: Low plasma proprotein convertase subtilisin kexin type-9 (PCSK9) concentration has been associated with loss of function (LOF) PCSK9 mutations in several studies. However, the current standard for detection of these LOF mutations is through gene sequencing. Gene sequencing is labor intensive and expensive. Identifying a simple test to help predict PCSK9 LOF mutations would help to better target subjects requiring gene sequencing. OBJECTIVES: Determine the diagnostic accuracy of plasma PCSK9 concentration in detecting PCSK9 LOF mutations using genotyping as the gold standard...
January 2017: Journal of Clinical Lipidology
https://www.readbyqxmd.com/read/28375029/emerging-experience-with-meningococcal-serogroup-b-protein-vaccines
#15
REVIEW
Daniela Toneatto, Mariagrazia Pizza, Vega Masignani, Rino Rappuoli
The successful development of two broadly protective vaccines targeting Neisseria meningitidis serogroup B (MenB); 4CMenB and rLP2086, is the most significant recent advance in meningococcal disease prevention. Areas covered: Here we review the principles underlying the development of each vaccine and the novel methods used to estimate vaccine coverage. We update clinical and post-licensure experience with 4CMenB and rLP2086. Expert commentary: The immunogenicity and acceptable safety profile of 4CMenB and rLP2086 has been demonstrated in clinical trials...
May 2017: Expert Review of Vaccines
https://www.readbyqxmd.com/read/28372589/the-first-canadian-experience-with-the-afirma%C3%A2-gene-expression-classifier-test
#16
Emily Kay-Rivest, Jamie Tibbo, Sarah Bouhabel, Michael Tamilia, Rebecca Leboeuf, Veronique-Isabelle Forest, Michael P Hier, Loren Savoury, Richard J Payne
BACKGROUND: Thyroid nodules are common and often benign, although prove to be malignant upon surgical pathology in 5-15% of cases. When assessed with ultrasound-guided fine-needle aspiration (USFNA), 15-30% of the nodules yield an indeterminate result. The Afirma® gene expression classifier (AGEC) was developed to improve management of indeterminate thyroid nodules (ITNs) by classifying them as "benign" or "suspicious." Objectives were (1) to assess the performance of the AGEC in two Canadian academic medical centres (2), to search for inter-institutional variation and (3) to compare AGEC performance in Canadian versus American institutions...
April 4, 2017: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/28367784/development-and-validation-of-the-perceived-food-environment-questionnaire-in-a-french-canadian-population
#17
Elise Carbonneau, Julie Robitaille, Benoît Lamarche, Louise Corneau, Simone Lemieux
OBJECTIVE: The present study aimed to develop and validate a questionnaire assessing perceived food environment in a French-Canadian population. DESIGN: A questionnaire, the Perceived Food Environment Questionnaire, was developed assessing perceived accessibility to healthy (nine items) and unhealthy foods (three items). A pre-test sample was recruited for a pilot testing of the questionnaire. For the validation study, another sample was recruited and completed the questionnaire twice...
April 3, 2017: Public Health Nutrition
https://www.readbyqxmd.com/read/28366104/adult-scandinavians-use-of-powered-scooters-user-satisfaction-frequency-of-use-and-prediction-of-daily-use
#18
Terje Sund, Åse Brandt
PURPOSE: To investigate user satisfaction with characteristics of powered scooters (scooters), frequency of use, and factors predicting daily scooter use. DESIGN: Cross-sectional. SAMPLE: Adult scooter users (n = 59) in Denmark and Norway, mean age 74.5 (standard deviation 12.3) years. METHODS: Structured face-to-face interviews. The NOMO 1.0, the Quebec User Evaluation of Satisfaction with assistive devices (QUEST 2...
April 1, 2017: Disability and Rehabilitation. Assistive Technology
https://www.readbyqxmd.com/read/28359275/leg-pain-location-and-neurological-signs-relate-to-outcomes-in-primary-care-patients-with-low-back-pain
#19
Lisbeth Hartvigsen, Lise Hestbaek, Charlotte Lebouef-Yde, Werner Vach, Alice Kongsted
BACKGROUND: Low back pain (LBP) patients with related leg pain and signs of nerve root involvement are considered to have a worse prognosis than patients with LBP alone. However, it is unclear whether leg pain location above or below the knee and the presence of neurological signs are important in primary care patients. The objectives of this study were to explore whether the four Quebec Task Force categories (QTFC) based on the location of pain and on neurological signs have different characteristics at the time of care seeking, whether these QTFC are associated with outcome, and if so whether there is an obvious ranking of the four QTFC on the severity of outcomes...
March 31, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28353402/everyday-ethics-of-participation-a-case-study-of-a-cbpr-in-nunavik
#20
Sarah Fraser, Georgia Vrakas, Arlene Laliberté, Raymond Mickpegak
INTRODUCTION: Multiple reports highlight the need for community-based family-oriented prevention services for Aboriginal peoples in order to address important health and social inequalities. Participatory, empowerment-based approaches are generally favoured for these means. Faced with important social issues, in a context of colonisation and complex power dynamics, we question how community members experience participation, as well as the everyday dynamics that take place when attempting to create community-level change...
March 1, 2017: Global Health Promotion
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