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Québec -Canada

Youssef Allami, Frank Vitaro, Mara Brendgen, René Carbonneau, Richard E Tremblay
Past studies have identified various risk and protective factors for problem gambling (PG). However, no study has examined the interplay between these factors using a combination of person-centered and variable-centered approaches embedded within a longitudinal design. The present study aimed to (a) identify distinct profiles in early adolescence based on a set of risk factors commonly associated with PG (impulsivity, depression, anxiety, drug-alcohol use, aggressiveness, and antisociality), (b) explore the difference in reported gambling problems between these profiles during midadolescence and early adulthood, and (c) identify family- and peer-related variables that could operate as protective or compensatory factors in this context...
March 19, 2018: Psychology of Addictive Behaviors: Journal of the Society of Psychologists in Addictive Behaviors
Kevin Smith, Jude Mary Cénat, Andréanne Lapierre, Jacinthe Dion, Martine Hébert, Karine Côté
BACKGROUND: Adolescents in a dating relationship can interact anytime using information and communication technologies. Yet, despite associated potential benefits, this availability of means to reach out to their partner may also exacerbate possible conflictual exchanges, including dating violence through technology. This study aimed to document the prevalence of cyber dating violence (CDV) victimization and perpetration among teenagers. It also explored self-esteem and psychological distress in participants having been perpetrators, victims, or perpetrator-victims, compared with those not having experienced CDV...
February 17, 2018: Journal of Affective Disorders
Sylvie Perreault, Payman Shahabi, Robert Côté, Stéphanie Dumas, Étienne Rouleau-Mailloux, Yassamin Feroz Zada, Sylvie Provost, Ian Mongrain, Marc Dorais, Thao Huynh, Simon Kouz, Ariel Diaz, Mark Blostein, Simon de Denus, Jacques Turgeon, Jeffrey Ginsberg, Jacques Lelorier, Lyne Lalonde, Lambert Busque, Jeannine Kassis, Mario Talajic, Jean-Claude Tardif, Marie-Pierre Dubé
BACKGROUND: Over- and under-coagulation with warfarin is associated with hemorrhagic and thromboembolic events, respectively. Genetic and clinical factors affect warfarin response, and the causes of this variability remain unclear. We present descriptive statistics and test for predictors of poor anticoagulation control. METHODS: The Quebec Warfarin Cohort (QWC) comprises 1,059 new warfarin users, with prospective follow up using telephone questionnaires every 3 months for one year, and using healthcare administrative databases (RAMQ and Med-Echo) for 5-year prior to cohort entry and up to 10-years following active patient participation...
March 15, 2018: Clinical Cardiology
Marc-Etienne Parent, François Vézina, Nathalie Carrier, Ariel Masetto
OBJECTIVE: To analyze the indications for and clinical procedures resulting from knee magnetic resonance imaging (MRI) in older patients. DESIGN: We retrospectively analyzed 215 medical records of patients 50 years of age and older who had undergone a unilateral knee MRI in 2009. SETTING: Centre hospitalier universitaire de Sherbrooke in Quebec. PARTICIPANTS: Patients 50 years of age and older who underwent a knee MRI in 2009...
March 2018: Canadian Family Physician Médecin de Famille Canadien
Jean-Michel Costes, Sylvia Kairouz, Eva Monson, Vincent Eroukmanoff
Lotteries are one of the most prevalent forms of gambling and generate substantial state revenues. They are also argued to be one of the least harmful forms of gambling. This paper is one of the first to examine exclusive lottery gamblers and compares their gambling patterns and problems as well other associated risky behaviours to those who are not exclusive lottery gamblers. Data were derived from two large surveys conducted with representative adult samples in France (n = 15,635) and Québec (n = 23,896)...
March 13, 2018: Journal of Gambling Studies
William Virgil Brown, Ira Goldberg, Barton Duell, Daniel Gaudet
Plasma triglyceride concentrations are normally below 150 mg/dL in the fasting state. However, these lipids can reach values of several thousand mg/dL. Elevations in this range are due to a massive retention of chylomicrons and usually result from multiple genetic variants with superimposed influences such as diabetes and immune disorders. Less commonly, major gene defects in lipoprotein metabolism can be the cause. These may present soon after birth with strong evidence of familial penetrance. The causes of this syndrome have been discussed in a Roundtable published in the most recent issue of this Journal...
March 5, 2018: Journal of Clinical Lipidology
Xavier Trudel, Mahée Gilbert-Ouimet, Alain Milot, Caroline S Duchaine, Michel Vézina, Danielle Laurin, Hélène Sultan-Taïeb, Chantal Brisson
No abstract text is available yet for this article.
March 9, 2018: International Journal of Epidemiology
Louis Raymond, Guy Paré, Éric Maillet, Ana Ortiz de Guinea, Marie-Claude Trudel, Josianne Marsan
BACKGROUND: The accessibility of laboratory test results is crucial to the performance of emergency departments and to the safety of patients. This study aims to develop a better understanding of which laboratory information exchange (LIE) systems emergency care physicians (ECPs) are using to consult their patients' laboratory test results and which benefits they derive from such use. METHODS: A survey of 163 (36%) ECPs in Quebec was conducted in collaboration with the Quebec's Department of Health and Social Services...
March 12, 2018: International Journal of Emergency Medicine
Noémie Graignic, Francine Tremblay, Yves Bergeron
Due to climate change, the ranges of many North American tree species are expected to shift northward. Sugar maple ( Acer saccharum Marshall) reaches its northern continuous distributional limit in northeastern North America at the transition between boreal mixed-wood and temperate deciduous forests. We hypothesized that marginal fragmented northern populations from the boreal mixed wood would have a distinct pattern of genetic structure and diversity. We analyzed variation at 18 microsatellite loci from 23 populations distributed along three latitudinal transects (west, central, and east) that encompass the continuous-discontinuous species range...
March 2018: Ecology and Evolution
Barbara Kermode-Scott
No abstract text is available yet for this article.
March 12, 2018: BMJ: British Medical Journal
Linda S Pagani, Caroline Fitzpatrick
PURPOSE: We examined the prospective influence of early child problematic behavior on later coercive interactions and binge drinking by mothers. DESIGN AND METHODS: Canadian participants are from the Quebec Longitudinal Study of Child Development, born between spring 1997 and 1998, which allowed a longitudinal birth cohort design. At the 41months, 628 parents reported on children's oppositional, aggressive, turbulent, and inattentive/hyperactive behavior. Mothers then reported on their own coercive and binge drinking behavior at the 60month follow-up...
March 2018: Journal of Pediatric Nursing
Antonios Douros, Laurent Azoulay, Hui Yin, Samy Suissa, Christel Renoux
BACKGROUND: Non-vitamin K antagonist oral anticoagulants (NOACs) are relatively new drugs used for stroke prevention in nonvalvular atrial fibrillation (NVAF). However, there are concerns that their use may be associated with hepatotoxic effects. OBJECTIVES: The purpose of this study was to determine whether the use of NOACs is associated with an increased risk of serious liver injury compared with the use of vitamin K antagonists (VKAs) in NVAF patients with and without prior liver disease...
March 13, 2018: Journal of the American College of Cardiology
Sophie Lauzier, Hichem Kadachi, Jocelyne Moisan, Alain Vanasse, Alain Lesage, Marie-Josée Fleury, Jean-Pierre Grégoire
OBJECTIVE: To assess whether neighbourhood deprivation is associated with exposure to an antidepressant drug treatment (ADT) and its quality among individuals diagnosed with unipolar depression and insured by the Quebec public drug plan. METHOD: We conducted an administrative database cohort study of adults covered by the Quebec public drug plan who were diagnosed with a new episode of unipolar depression. We assessed material and social deprivation using an area-based index...
January 1, 2018: Canadian Journal of Psychiatry. Revue Canadienne de Psychiatrie
Marie-Josée Fleury, Judith Sabetti, Jean-Marie Bamvita
While mental health (MH) services are expected to support client recovery, very little is known about services provided by MH teams in relation to this goal. This study explored relationships between a comprehensive collection of team effectiveness variables and the perspectives of MH professionals regarding the recovery orientation of their teams. A model developed by path analysis revealed eight team-related variables that were significantly and positively associated with recovery-oriented teams: primary care versus specialized MH services; greater proportions of clients with severe mental disorders or with suicide ideation on caseloads; knowledge sharing and knowledge production among team members; team climate; work role performance; and trust in coworkers...
March 6, 2018: Journal of Behavioral Health Services & Research
Marie-Julie Favé, Fabien C Lamaze, David Soave, Alan Hodgkinson, Héloïse Gauvin, Vanessa Bruat, Jean-Christophe Grenier, Elias Gbeha, Kimberly Skead, Audrey Smargiassi, Markey Johnson, Youssef Idaghdour, Philip Awadalla
Uncovering the interaction between genomes and the environment is a principal challenge of modern genomics and preventive medicine. While theoretical models are well defined, little is known of the G × E interactions in humans. We used an integrative approach to comprehensively assess the interactions between 1.6 million data points, encompassing a range of environmental exposures, health, and gene expression levels, coupled with whole-genome genetic variation. From ∼1000 individuals of a founder population in Quebec, we reveal a substantial impact of the environment on the transcriptome and clinical endophenotypes, overpowering that of genetic ancestry...
March 6, 2018: Nature Communications
Charles Hubert Blouin-Delisle, Renee Drolet, Serge Gagnon, Stephane Turcotte, Sylvie Boutet, Martin Coulombe, Eric Daneau
Purpose The purpose of this paper is to increase efficiency in ORs without affecting quality of care by improving the workflow processes. Administrative processes independent of the surgical act can be challenging and may lead to clinical impacts such as increasing delays. The authors hypothesized that a Lean project could improve efficiency of surgical processes by reducing the length of stays in the recovery ward. Design/methodology/approach Two similar Lean projects were performed in the surgery departments of two hospitals of the Centre Hospitalier Universitaire de Québec: Hôtel Dieu de Quebec (HDQ) and Hôpital de l'Enfant Jesus (HEJ)...
March 12, 2018: International Journal of Health Care Quality Assurance
Cynthia Picard, Cédric Julien, Josée Frappier, Justin Miron, Louise Théroux, Doris Dea, John C S Breitner, Judes Poirier
Genome-wide association studies have identified several cholesterol metabolism-related genes as top risk factors for late-onset Alzheimer's disease (LOAD). We hypothesized that specific genetic variants could act as disease-modifying factors by altering the expression of those genes. Targeted association studies were conducted with available genomic, transcriptomic, proteomic, and histopathological data from 3 independent cohorts: the Alzheimer's Disease Neuroimaging Initiative (ADNI), the Quebec Founder Population (QFP), and the United Kingdom Brain Expression Consortium (UKBEC)...
February 9, 2018: Neurobiology of Aging
Marie-Claude Letellier, Caroline S Duchaine, Karine Aubé, Denis Talbot, Marie-Michèle Mantha-Bélisle, Hélène Sultan-Taïeb, France St-Hilaire, Caroline Biron, Michel Vézina, Chantal Brisson
Adverse psychosocial work factors are recognized as a significant source of psychological distress, resulting in a considerable socioeconomic burden. The impact of occupational health standards that aim to reduce these adverse work factors, such as the Quebec Healthy Enterprise Standard (QHES), is of great interest for public health. The aim of this study was to evaluate, for the first time, the effect of QHES interventions targeting adverse psychosocial work factors on the prevalence of these factors and of psychological distress among ten Quebec organizations...
February 28, 2018: International Journal of Environmental Research and Public Health
Michelle Bergeron, Genevieve Nadeau, Katherine Moore
INTRODUCTION: Intradetrusor injections of onabotulinumtoxinA (BoNTA) is well-established as treatment for patients with neurogenic bladders. Urodynamics (UDS) are used at regular intervals during followup to monitor intravesical pressure. With regards to the discomfort and risks associated with UDS, our objective was to assess if UDS done at regular intervals in the followup of neurogenic bladders treated with BoNTA had an impact on management. METHODS: We retrospectively analyzed the medical records of adult patients with neurologic disorders treated with BoNTA for either detrusor overactivity or low bladder compliance at the Institut de Réadaptation en Déficience Physique de Québec (IRDPQ)...
February 23, 2018: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
Lauren Vogel
No abstract text is available yet for this article.
February 26, 2018: CMAJ: Canadian Medical Association Journal, Journal de L'Association Medicale Canadienne
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