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https://www.readbyqxmd.com/read/29051907/online-bci-typing-using-language-model-classifiers-by-als-patients-in-their-homes
#1
William Speier, Nand Chandravadia, Dustin Roberts, S Pendekanti, Nader Pouratian
The P300 speller is a common brain-computer interface system that can provide a means of communication for patients with amyotrophic lateral sclerosis (ALS). Recent studies have shown that incorporating language information in signal classification can improve system performance, but they have largely been tested on healthy volunteers in a laboratory setting. The goal of this study was to demonstrate the functionality of the P300 speller system with language models when used by ALS patients in their homes. Six ALS patients with functional ratings ranging from two to 28 participated in this study...
2017: Brain Computer Interfaces
https://www.readbyqxmd.com/read/29051688/facilitating-motor-imagery-based-brain-computer-interface-for-stroke-patients-using-passive-movement
#2
Mahnaz Arvaneh, Cuntai Guan, Kai Keng Ang, Tomas E Ward, Karen S G Chua, Christopher Wee Keong Kuah, Gopal Joseph Ephraim Joseph, Kok Soon Phua, Chuanchu Wang
Motor imagery-based brain-computer interface (MI-BCI) has been proposed as a rehabilitation tool to facilitate motor recovery in stroke. However, the calibration of a BCI system is a time-consuming and fatiguing process for stroke patients, which leaves reduced time for actual therapeutic interaction. Studies have shown that passive movement (PM) (i.e., the execution of a movement by an external agency without any voluntary motions) and motor imagery (MI) (i.e., the mental rehearsal of a movement without any activation of the muscles) induce similar EEG patterns over the motor cortex...
2017: Neural Computing & Applications
https://www.readbyqxmd.com/read/29050982/pharmacological-inhibition-of-dusp6-suppresses-gastric-cancer-growth-and-metastasis-and-overcomes-cisplatin-resistance
#3
Qi-Nian Wu, Yi-Fu Liao, Yun-Xin Lu, Yun Wang, Jia-Huan Lu, Zhao-Lei Zeng, Qi-Tao Huang, Hui Sheng, Jing-Ping Yun, Dan Xie, Huai-Qiang Ju, Rui-Hua Xu
Gastric cancer (GC) is the second cause of cancer-related death. Cisplatin (CDDP) is widely used as the standard GC treatment, but relapse and metastasis are common because of intrinsic or acquired drug resistance. The mitogen-activated protein kinase phosphatases (MAPK)-extracellular signal regulated kinases (ERK) pathway contributes to GC progression and drug resistance, but targeting the MAPK-ERK pathway is challenging in GC therapy. Here, we demonstrated that dual-specificity phosphatases 6 (DUSP6) was overexpressed in GC and predicted poor overall survival and progression-free survival...
October 16, 2017: Cancer Letters
https://www.readbyqxmd.com/read/29047393/the-human-behaviour-change-project-harnessing-the-power-of-artificial-intelligence-and-machine-learning-for-evidence-synthesis-and-interpretation
#4
Susan Michie, James Thomas, Marie Johnston, Pol Mac Aonghusa, John Shawe-Taylor, Michael P Kelly, Léa A Deleris, Ailbhe N Finnerty, Marta M Marques, Emma Norris, Alison O'Mara-Eves, Robert West
BACKGROUND: Behaviour change is key to addressing both the challenges facing human health and wellbeing and to promoting the uptake of research findings in health policy and practice. We need to make better use of the vast amount of accumulating evidence from behaviour change intervention (BCI) evaluations and promote the uptake of that evidence into a wide range of contexts. The scale and complexity of the task of synthesising and interpreting this evidence, and increasing evidence timeliness and accessibility, will require increased computer support...
October 18, 2017: Implementation Science: IS
https://www.readbyqxmd.com/read/29046625/assessing-the-depth-of-cognitive-processing-as-the-basis-for-potential-user-state-adaptation
#5
Irina-Emilia Nicolae, Laura Acqualagna, Benjamin Blankertz
Objective: Decoding neurocognitive processes on a single-trial basis with Brain-Computer Interface (BCI) techniques can reveal the user's internal interpretation of the current situation. Such information can potentially be exploited to make devices and interfaces more user aware. In this line of research, we took a further step by studying neural correlates of different levels of cognitive processes and developing a method that allows to quantify how deeply presented information is processed in the brain. Methods/Approach: Seventeen participants took part in an EEG study in which we evaluated different levels of cognitive processing (no processing, shallow, and deep processing) within three distinct domains (memory, language, and visual imagination)...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/29046111/eeg-classification-with-a-sequential-decision-making-method-in-motor-imagery-bci
#6
Rong Liu, Yongxuan Wang, Geoffrey I Newman, Nitish V Thakor, Sarah Ying
To develop subject-specific classifier to recognize mental states fast and reliably is an important issue in brain-computer interfaces (BCI), particularly in practical real-time applications such as wheelchair or neuroprosthetic control. In this paper, a sequential decision-making strategy is explored in conjunction with an optimal wavelet analysis for EEG classification. The subject-specific wavelet parameters based on a grid-search method were first developed to determine evidence accumulative curve for the sequential classifier...
September 7, 2017: International Journal of Neural Systems
https://www.readbyqxmd.com/read/29035204/four-novel-motion-paradigms-based-on-steady-state-motion-visual-evoked-potential
#7
Wenqiang Yan, Guanghua Xu, Jun Xie, Min Li, Ziyan Dan
OBJECTIVE: The purpose of this work was to study the applicability of paradigms with motion forms for use in a brain-computer interface (BCI). We examined the performances of different paradigms and evaluated the stimulus effects. METHODS: We designed four novel stimulus paradigms based on basic motion modes: swing, rotation, spiral, and radial contraction-expansion. Canonical correlation analysis (CCA) was used to analyze the accuracy. Additionally, we optimized CCA template signal harmonic combinations for the different motion paradigms...
October 13, 2017: IEEE Transactions on Bio-medical Engineering
https://www.readbyqxmd.com/read/29031463/changes-in-brain-activity-during-action-observation-and-motor-imagery-their-relationship-with-motor-learning
#8
Nobuaki Mizuguchi, Kazuyuki Kanosue
Many studies have demonstrated that training utilizing action observation and/or motor imagery improves motor performance. These two techniques are widely used in sports and in the rehabilitation of movement-related disorders. Motor imagery has also been used for brain-machine/computer interfaces (BMI/BCI). During both action observation and motor imagery, motor-related regions such as the premotor cortex and inferior parietal lobule are activated. This is common to actual execution and are involved with the underlying mechanisms of motor learning without execution...
2017: Progress in Brain Research
https://www.readbyqxmd.com/read/29028186/decoding-covert-somatosensory-attention-by-a-bci-system-calibrated-with-tactile-sensation
#9
Lin Yao, Xinjun Sheng, Natalie Mrachacz-Kersting, Xiangyang Zhu, Dario Farina, Ning Jiang
OBJECTIVE: We propose a novel calibration strategy to facilitate the decoding of covert somatosensory attention by exploring the oscillatory dynamics induced by tactile sensation. METHODS: It was hypothesized that the similarity of the oscillatory pattern between stimulation sensation (SS, real sensation) and somatosensory attentional orientation (SAO) provides a way to decode covert somatic attention. Subjects were instructed to sense the tactile stimulation, which was applied to the left (SS-L) or the right (SS-R) wrist...
October 12, 2017: IEEE Transactions on Bio-medical Engineering
https://www.readbyqxmd.com/read/29024794/brain-computer-interface-with-the-p300-speller-usability-for-disabled-people-with-amyotrophic-lateral-sclerosis
#10
Violaine Guy, Marie-Hélène Soriani, Mariane Bruno, Théodore Papadopoulo, Claude Desnuelle, Maureen Clerc
OBJECTIVES: Amyotrophic lateral sclerosis (ALS), a progressive neurodegenerative disease, restricts patients' communication capacity a few years after onset. A proof-of-concept of brain-computer interface (BCI) has shown promise in ALS and "locked-in" patients, mostly in pre-clinical studies or with only a few patients, but performance was estimated not high enough to support adoption by people with physical limitation of speech. Here, we evaluated a visual BCI device in a clinical study to determine whether disabled people with multiple deficiencies related to ALS would be able to use BCI to communicate in a daily environment...
October 9, 2017: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/29021985/turbo-satori-a-neurofeedback-and-brain-computer-interface-toolbox-for-real-time-functional-near-infrared-spectroscopy
#11
Michael Lührs, Rainer Goebel
Turbo-Satori is a neurofeedback and brain-computer interface (BCI) toolbox for real-time functional near-infrared spectroscopy (fNIRS). It incorporates multiple pipelines from real-time preprocessing and analysis to neurofeedback and BCI applications. The toolbox is designed with a focus in usability, enabling a fast setup and execution of real-time experiments. Turbo-Satori uses an incremental recursive least-squares procedure for real-time general linear model calculation and support vector machine classifiers for advanced BCI applications...
October 2017: Neurophotonics
https://www.readbyqxmd.com/read/29019425/communication-of-behaviour-change-interventions-can-they-be-recognised-from-written-descriptions
#12
Marie Johnston, Derek Johnston, Caroline E Wood, Wendy Hardeman, Jill Francis, Susan Michie
OBJECTIVE: Communication of the content of a behaviour change intervention (BCI) involves clear description followed by appropriate recognition and interpretation. We investigated accuracy of recognition of BCI descriptions and the effects of training in the behaviour change taxonomy BCTTv1. METHODS: Materials were 166 written descriptions of two BCIs previously written by 166 separate writers after viewing a video of the BCI. Each of the current participants (12 naïve and 12 trained in BCTTv1) was presented with a random sample of the written descriptions and asked to form groups of descriptions they judged to be describing the same intervention...
October 11, 2017: Psychology & Health
https://www.readbyqxmd.com/read/29017899/a-brain-computer-interface-based-on-functional-transcranial-doppler-ultrasound-using-wavelet-transform-and-support-vector-machines
#13
Aya Khalaf, Matthew Sybeldon, Ervin Sejdic, Murat Akcakaya
BACKGROUND: Functional transcranial Doppler (fTCD) is an ultrasound based neuroimaging technique used to assess neural activation that occurs during a cognitive task through measuring velocity of cerebral blood flow. NEW METHOD: The objective of this paper is to investigate the feasibility of a 2-class and 3-class real-time BCI based on blood flow velocity in left and right middle cerebral arteries in response to mental rotation and word generation tasks. Statistical features based on a five-level wavelet decomposition were extracted from the fTCD signals...
October 7, 2017: Journal of Neuroscience Methods
https://www.readbyqxmd.com/read/28987501/composite-alginate-hyaluronan-sponges-for-the-delivery-of-tranexamic-acid-in-post-extractive-alveolar-wounds
#14
Ovidio Catanzano, Vittoria D'Esposito, Pietro Formisano, Joshua S Boateng, Fabiana Quaglia
The management of wounds in patients on anticoagulant therapy who require oral surgical procedures is problematic and often results in a non-satisfactory healing process. Here we report a method to prepare an advanced dressing able to avoid uncontrolled bleeding by occluding the post-extractive alveolar wounds, and simultaneously, capable of a fast release of tranexamic acid (TA). Composite alginate/hyaluronan (ALG/HA) sponge dressings loaded with TA were prepared by a straightforward internal gelation method followed by a freeze-drying step...
October 5, 2017: Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28983244/role-of-the-contralesional-vs-ipsilesional-hemisphere-in-stroke-recovery
#15
REVIEW
Keith C Dodd, Veena A Nair, Vivek Prabhakaran
Following a stroke, the resulting lesion creates contralateral motor impairment and an interhemispheric imbalance involving hyperexcitability of the contralesional hemisphere. Neuronal reorganization may occur on both the ipsilesional and contralesional hemispheres during recovery to regain motor functionality and therefore bilateral activation for the hemiparetic side is often observed. Although ipsilesional hemispheric reorganization is traditionally thought to be most important for successful recovery, definitive conclusions into the role and importance of the contralesional motor cortex remain under debate...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28983235/affective-stimuli-for-an-auditory-p300-brain-computer-interface
#16
Akinari Onishi, Kouji Takano, Toshihiro Kawase, Hiroki Ora, Kenji Kansaku
Gaze-independent brain computer interfaces (BCIs) are a potential communication tool for persons with paralysis. This study applies affective auditory stimuli to investigate their effects using a P300 BCI. Fifteen able-bodied participants operated the P300 BCI, with positive and negative affective sounds (PA: a meowing cat sound, NA: a screaming cat sound). Permuted stimuli of the positive and negative affective sounds (permuted-PA, permuted-NA) were also used for comparison. Electroencephalography data was collected, and offline classification accuracies were compared...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28981448/asynchronous-brain-computer-interface-for-cognitive-assessment-in-people-with-cerebral-palsy
#17
R E Alcaide-Aguirre, S A Warschausky, D Brown, A Aref, J E Huggins
OBJECTIVE: Typically, clinical measures of cognition require motor or speech responses. Thus, a significant percentage of people with disabilities are not able to complete standardized assessments. This situation could be resolved by employing a more accessible test administration method, such as a brain-computer interface (BCI). A BCI can circumvent motor and speech requirements by translating brain activity to identify a subject's response. By eliminating the need for motor or speech input, one could use a BCI to assess an individual who previously did not have access to clinical tests...
October 5, 2017: Journal of Neural Engineering
https://www.readbyqxmd.com/read/28981418/covert-verb-reading-contributes-to-signal-classification-of-motor-imagery-in-bci
#18
Hong Zhang, Yaoru Sun, Jie Li, Fang Wang, Zijian Wang
Motor imagery is widely used in the brain-computer interface (BCI) systems that can help people actively control devices to directly communicate with the external world, but its training and performance effect is usually poor for normal people. To improve operators' BCI performances, here we proposed a novel paradigm, which combined the covert verb reading in the traditional motor imagery paradigm. In our proposed paradigm, participants were asked to covertly read the presented verbs during imagining right hand or foot movements referred by those verbs...
October 4, 2017: IEEE Transactions on Neural Systems and Rehabilitation Engineering
https://www.readbyqxmd.com/read/28967866/discriminative-codewaves-a-symbolic-dynamics-approach-to-ssvep-recognition-for-asynchronous-bci
#19
Konstantinos Ilias Georgiadis, Nikolaos Laskaris, Spiros Nikolopoulos, Yiannis Kompatsiaris
Steady-state visual evoked potential (SSVEP) is a very popular approach to establishing a communication pathway in brain computer interfaces (BCIs), without any training requirements for the user. Brain activity recorded over occipital regions, in association with stimuli flickering at distinct frequencies, is used to predict the gaze direction. High performance is achieved when the analysis of multichannel signal is guided by the driving signals. It is the scope of this study to introduce an efficient way to identify the attended stimulus without the need to register the driving signals...
October 2, 2017: Journal of Neural Engineering
https://www.readbyqxmd.com/read/28966581/enhancing-performance-of-a-hybrid-eeg-fnirs-system-using-channel-selection-and-early-temporal-features
#20
Rihui Li, Thomas Potter, Weitian Huang, Yingchun Zhang
Brain-Computer Interface (BCI) techniques hold a great promise for neuroprosthetic applications. A desirable BCI system should be portable, minimally invasive, and feature high classification accuracy and efficiency. As two commonly used non-invasive brain imaging modalities, Electroencephalography (EEG) and functional near-infrared spectroscopy (fNIRS) BCI system have often been incorporated in the development of hybrid BCI systems, largely due to their complimentary properties. In this study, we aimed to investigate whether the early temporal information extracted from singular EEG and fNIRS channels on each hemisphere can be used to enhance the accuracy and efficiency of a hybrid EEG-fNIRS BCI system...
2017: Frontiers in Human Neuroscience
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