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Left atrial appendage occlusion

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https://www.readbyqxmd.com/read/29760285/occurrence-of-incomplete-endothelialization-causing-residual-permeability-after-left-atrial-appendage-closure
#1
Mathieu Granier, Guillaume Laugaudin, François Massin, Stephane Cade, Pierre François Winum, Cornelia Freitag, Jean-Luc Pasquie
AIMS: Percutaneous left atrial appendage (LAA) occlusion is occasionally incomplete, with residual permeability of the LAA on cardiac computed tomography. The cause for this is unclear. Our objective was to determine if residual permeability was related to incomplete endothelialization. METHODS: A total of 35 consecutive patients contraindicated for anticoagulant therapy admitted for LAA occlusion were included; 12 patients received a Watchman device (Boston Scientific) and 23 patients received an Amplatzer Cardiac Plug (St...
May 15, 2018: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/29759706/the-human-left-atrial-venous-circulation-as-a-vascular-route-for-atrial-pharmacological-therapies-effects-of-ethanol-infusion
#2
Miguel Valderrábano, Percy Francisco Morales, Moisés Rodríguez-Mañero, Candela Lloves, Paul A Schurmann, Amish S Dave
OBJECTIVES: This study catalogued the human venous left atrium (LA) circulation system and the ablative effects of ethanol in different branches. BACKGROUND: Vascular routes to target the LA could have significant therapeutic potential. Beyond the vein of Marshall (VOM), the fluoroscopic LA venous anatomy has not been described. METHODS: Patients undergoing ethanol infusion in the VOM as adjunctive therapy to atrial fibrillation (AF) catheter ablation were included in this study...
September 2017: JACC. Clinical Electrophysiology
https://www.readbyqxmd.com/read/29759668/incidence-characteristics-and-clinical-course-of-device-related-thrombus-after-watchman-left-atrial-appendage-occlusion-device-implantation-in-atrial-fibrillation-patients
#3
Shunsuke Kubo, Yukiko Mizutani, Krissada Meemook, Yoshifumi Nakajima, Asma Hussaini, Saibal Kar
OBJECTIVES: This study investigated characteristics and clinical impact of device-related thrombus formation after Watchman device implantation in atrial fibrillation (AF) patients. BACKGROUND: Left atrial appendage occlusion using the Watchman device is an effective alternative to anticoagulation for stroke prevention in AF patients. However, device-related thrombus formation remains an important concern after Watchman implantation. METHODS: From 2006 to 2014, 119 consecutive AF patients underwent Watchman implantation...
December 11, 2017: JACC. Clinical Electrophysiology
https://www.readbyqxmd.com/read/29759665/thoracoscopic-left-atrial-appendage-occlusion-we-can-do-it-now-should-we
#4
EDITORIAL
Richard Whitlock, Sarah MacIsaac, Stuart Connolly
No abstract text is available yet for this article.
December 11, 2017: JACC. Clinical Electrophysiology
https://www.readbyqxmd.com/read/29759664/angiographic-efficacy-of-the-atriclip-left-atrial-appendage-exclusion-device-placed-by-minimally-invasive-thoracoscopic-approach
#5
Christopher R Ellis, Sam G Aznaurov, Neel J Patel, Jennifer R Williams, Kim Lori Sandler, Steven J Hoff, Stephen K Ball, S Patrick Whalen, John Jeffrey Carr
OBJECTIVES: This study sought to assess long-term left atrial appendage (LAA) closure efficacy of the Atriclip applied via totally thoracoscopic (TT) approach with computed tomographic angiography. BACKGROUND: LAA closure is associated with a low risk for atrial fibrillation-related embolic stroke. The Atriclip exclusion device allows epicardial LAA closure, avoiding the need for post-operative oral anticoagulation. Previous data with Atriclip during open chest procedures show a high efficacy rate of closure >95%...
December 11, 2017: JACC. Clinical Electrophysiology
https://www.readbyqxmd.com/read/29728202/case-based-discussion-regarding-challenges-in-patient-selection-and-procedural-planning-in-left-atrial-appendage-occlusion
#6
REVIEW
Sidakpal S Panaich, Thomas Munger, Paul Friedman, Charanjit S Rihal, David R Holmes
Atrial fibrillation (AF) accounts for most embolic strokes, especially in elderly individuals. Although anticoagulation is known to reduce the risk of embolic stroke, a significant proportion of patients have relative or absolute contraindications to anticoagulation. The left atrial appendage has been implicated as the major source of emboli in more than 90% of ischemic strokes in nonvalvular AF. Left atrial appendage occlusion offers an alternative for stroke prevention in patients with an elevated stroke risk (CHADS2 score ≥2 or CHA2 DS2 -VASc score ≥3) who have a rationale for avoiding long-term oral anticoagulation after a shared decision-making process...
May 2018: Mayo Clinic Proceedings
https://www.readbyqxmd.com/read/29727507/optimal-combination-strategy-of-left-atrial-appendage-closure-plus-catheter-ablation-in-a-single-procedure-in-patients-with-nonvalvular-atrial-fibrillation
#7
Xianfeng Du, Huimin Chu, Bin He, Binhao Wang, Jing Liu, Mingjun Feng, Yibo Yu, Guohua Fu, He Jin, Fang Gao, Jingjing Zhu, Xiaomin Chen
BACKGROUND: The efficacy and safety of combining left atrial appendage closure (LAAC) plus atrial fibrillation (AF) catheter ablation (CA) in a single procedure has been established, but the optimal combination strategy has not been thoroughly elucidated to date. OBJECTIVE: We aimed to investigate the impact of different combination strategies on clinical outcomes. METHODS: Eighty-two consecutive patients with symptomatic AF (mean CHA2 DS2 -VASc score 4...
May 4, 2018: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/29706393/implant-success-and-safety-of-left-atrial-appendage-occlusion-in-end-stage-renal-disease-patients-peri-procedural-outcomes-from-an-italian-dialysis-population
#8
Simonetta Genovesi, Giorgio Slaviero, Luca Porcu, Gavino Casu, Silvio Bertoli, Antonio Sagone, Federico Pieruzzi, Giovanni Rovaris, Monique Buskermolen, Paolo Danna, Alberto Montoli, Jacopo Oreglia, Gina Contaldo, Patrizio Mazzone
AIMS: To estimate the safety and the efficacy of the off label left atrial appendage (LAA) occlusion in chronic dialysis patients with atrial fibrillation (AF). In this preliminary paper, we report the design of the study and the data on peri-procedural complications. METHODS: This is a prospective cohort study. Primary endpoints are i) incidence of peri-procedural complications, ii) cumulative incidence of two-year thromboembolic events iii) cumulative incidence of two-year bleedings iiii) mortality at two years...
July 1, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29696697/a-novel-double-snare-technique-to-retrieve-embolized-septal-and-left-atrial-appendage-occluders
#9
Kee Soo Ha, Jae Young Choi, Se Yong Jung, Jung-Sun Kim, Ki Hyun Byun, Teiji Akagi, Mirjamol M Zufarov
BACKGROUND: Device embolization is the most frequent procedural complication during transcatheter closure of congenital cardiac defects. Retrieval of an embolized device may often be complicated by failure to introduce the right atrial (RA) disk hub into the sheath or difficulty in securely grasping the hub pin of RA disk. We aimed to evaluate the efficiency and success rate of device retrieval using a novel double snare technique. METHODS: We reviewed retrieval procedures of embolized atrial septal defect (ASD) or left atrial appendage (LAA) occluder using double snare technique reported from five tertiary referral centers in Korea, Japan, and Uzbekistan...
April 25, 2018: Journal of Interventional Cardiology
https://www.readbyqxmd.com/read/29677021/pericardial-patch-exclusion-technique-for-left-atrial-appendage-closure
#10
Olivia K Ginty, Feras H Khaliel, Corey Adams, Michael W A Chu
We describe a technique of left atrial appendage occlusion that consists of autologous pericardial patch closure of the left atrial appendage orifice from within the left atrium. This pericardial patch exclusion technique has little added risk of bleeding, can be performed through sternotomy or right minithoracotomy, and can be used in re-operative situations.
April 19, 2018: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
https://www.readbyqxmd.com/read/29670888/computational-fluid-dynamic-analysis-of-the-left-atrial-appendage-to-predict-thrombosis-risk
#11
Giorgia Maria Bosi, Andrew Cook, Rajan Rai, Leon J Menezes, Silvia Schievano, Ryo Torii, Gaetano Burriesci
During Atrial Fibrillation (AF) more than 90% of the left atrial thrombi responsible for thromboembolic events originate in the left atrial appendage (LAA), a complex small sac protruding from the left atrium (LA). Current available treatments to prevent thromboembolic events are oral anticoagulation, surgical LAA exclusion, or percutaneous LAA occlusion. However, the mechanism behind thrombus formation in the LAA is poorly understood. The aim of this work is to analyse the hemodynamic behaviour in four typical LAA morphologies - "Chicken wing", "Cactus", "Windsock" and "Cauliflower" - to identify potential relationships between the different shapes and the risk of thrombotic events...
2018: Frontiers in Cardiovascular Medicine
https://www.readbyqxmd.com/read/29650978/percutaneous-closure-of-left-atrial-appendage-significantly-affects-lipidome-metabolism
#12
G Yücel, M Behnes, C Barth, A Wenke, B Sartorius, K Mashayekhi, B Yazdani, T Bertsch, J Rusnak, A Saleh, U Hoffmann, C Fastner, S Lang, X Zhou, K Sattler, M Borggrefe, I Akin
Patients with non-valvular atrial fibrillation (AF) and a high risk for oral anticoagulation can be treated by percutaneous implantation of left atrial appendage occlusion devices (LAAC) to reduce the risk of cardio-embolic stroke. This study evaluates whether LAAC may influence lipid metabolism, which has never been investigated before. Patients with successful LAAC were included consecutively. Venous peripheral blood samples of patients were collected immediately before (T0, baseline) and 6 months after (T1, mid-term) LAAC...
April 12, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29629551/totally-thoracoscopic-left-atrial-occlusion-concomitant-to-endoscopic-atraumatic-coronary-artery-bypass-grafting-eacab
#13
Piotr Suwalski, Anna Witkowska
Atrial fibrillation, as the most prevalent arrhythmia, has more impact on morbidity and mortality than any other rhythm disorder. It is often concomitant with structural heart diseases like coronary artery disease. The worst complication of atrial fibrillation is stroke, but the double or triple antithrombotic therapy especially in fragile and elderly patients is associated with significant risk of bleeding. The left atrial appendage occlusion may reduse both the risk of stroke and drug intake. Here we present, to our knowledge, the first description of a simultaneous totally thoracoscopic 3D augmented coronary artery bypass grafting and left atrial appendage occlusion...
March 15, 2018: Multimedia Manual of Cardiothoracic Surgery: MMCTS
https://www.readbyqxmd.com/read/29622160/left-atrial-appendage-occlusion-device-related-thrombus-certainties-and-uncertainties
#14
EDITORIAL
Miguel Valderrábano
No abstract text is available yet for this article.
April 10, 2018: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/29622159/device-related-thrombosis-after-percutaneous-left-atrial-appendage-occlusion-for-atrial-fibrillation
#15
Laurent Fauchier, Alexandre Cinaud, François Brigadeau, Antoine Lepillier, Bertrand Pierre, Selim Abbey, Marjaneh Fatemi, Frederic Franceschi, Paul Guedeney, Peggy Jacon, Olivier Paziaud, Sandrine Venier, Jean Claude Deharo, Daniel Gras, Didier Klug, Jacques Mansourati, Gilles Montalescot, Olivier Piot, Pascal Defaye
BACKGROUND: Transcatheter left atrial appendage (LAA) occlusion is an alternative strategy for stroke prevention in patients with atrial fibrillation (AF). OBJECTIVES: This study sought to determine the incidence, predictors, and prognosis of thrombus formation on devices in patients with AF who were treated with LAA closure. METHODS: The study retrospectively analyzed data from patients treated with 2 LAA closure devices seen in 8 centers in France from February 2012 to January 2017...
April 10, 2018: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/29607737/dual-antiplatelet-therapy-after-percutaneous-left-atrial-appendage-occlusion-single-center-experience-with-the-amplatzer-cardiac-plug
#16
Philippe B Bertrand, Melanie Habran, Karlijn Kenis, Julie Lecomte, Linde Moonen, Didier Stroobants, Edouard Benit
BACKGROUND: Percutaneous left atrial appendage occlusion (LAAO) is an alternative to anticoagulation in atrial fibrillation patients at high bleeding risk. Dual antiplatelet therapy (DAPT) is generally recommended in the months following the procedure to prevent thrombotic complications. The aim of this study was to evaluate the safety and efficacy of DAPT after LAAO in a single-centre population of high bleeding risk patients. METHODS: All patients who received DAPT after LAAO using the Amplatzer Cardiac Plug at Jessa Hospital (Hasselt, BE) between February 2011 and October 2016 were included...
April 1, 2018: Acta Cardiologica
https://www.readbyqxmd.com/read/29600775/left-atrial-appendage-electrical-isolation-for-treatment-of-recurrent-atrial-fibrillation-a-meta-analysis
#17
Daniel J Friedman, Eric W Black-Maier, Adam S Barnett, Sean D Pokorney, Sana M Al-Khatib, Kevin P Jackson, Tristram D Bahnson, Christopher R Ellis, Brett D Atwater, Robert K Lewis, Jonathan P Piccini
OBJECTIVES: In this study, the authors sought to perform a meta-analysis of controlled studies assessing the relationship between left atrial appendage (LAA) electrical isolation (EI) and recurrent atrial fibrillation (AF). BACKGROUND: LAA triggers could play an important role in AF and can be treated with complete EI of the LAA via surgical or percutaneous approaches. METHODS: We conducted a meta-analysis of all controlled studies published as of November 21, 2016, assessing the relationship between left atrial appendage electrical isolation (LAAEI) and recurrent AF...
January 2018: JACC. Clinical Electrophysiology
https://www.readbyqxmd.com/read/29590385/the-new-2016-european-society-of-cardiology-european-association-for-cardio-thoracic-surgery-guidelines-enough-guidance-enough-evidence
#18
Manuel Castellá
For the first time, the European Society of Cardiology and the European Association for Cardio-Thoracic Surgery have joined forces to develop consensus guidelines for the management of atrial fibrillation (AF). One of the main issues is the integrated care of patients with AF, with emphasis on multidisciplinary teams of general physicians, cardiologists, stroke specialists and surgeons, together with the patient's involvement for better management of AF. These guidelines also help in the detection of risk factors and concomitant cardiovascular diseases, stroke prevention therapies, including anticoagulation and antiplatelet therapies after acute coronary episodes, major haemorrhages or strokes...
April 1, 2018: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29582475/first-in-human-experience-of-left-atrial-appendage-occlusion-with-the-steerable-fustar-sheath
#19
Caroline Kleinecke, Omar Gomez Monterrosas, Giancarla Scalone, Yat-Yin Lam, Eun-Seok Shin, Barbara Bellmann, Johannes Brachmann, Jai-Wun Park
BACKGROUND: Due the wide variability of left atrial appendage morphology left atrial appendage occlusion (LAAO) remains a challenging procedure. The steerable FuStar delivery sheath was designed to allow both, transseptal access and delivery of percutaneous devices. We here report the first-in-human experience of LAAO with the FuStar sheath. METHODS: Twenty patients (76.6 ± 8.4 years; 12 (60%) males; CHA2 DS2 -VASc score: 5.0 ± 2) with non-valvular fibrillation and contraindications to oral anticoagulation underwent LAAO with the LAmbre device using the FuStar steerable sheath (Lifetech Scientific Corp...
March 26, 2018: Journal of Interventional Cardiology
https://www.readbyqxmd.com/read/29570041/percutaneous-left-atrial-appendage-occlusion-in-a-lamin-a-c-gene-mutation-related-cardiomyopathy-patient-with-persistent-left-atrial-appendage-thrombus-a-case-report
#20
Frederic De Roeck, Benjamin Scott, Stefan Verheye, Paul Vermeersch
No abstract text is available yet for this article.
March 23, 2018: Acta Cardiologica
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