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Left atrial appendage occlusion

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https://www.readbyqxmd.com/read/28225286/-closure-of-the-left-atrial-appendage-by-means-of-the-atriclip-system
#1
Aleš Mokráček, Vojtěch Kurfirst, Alan Bulava, Jiří Haniš
INTRODUCTION: Atrial fibrillation (AFib) is related to a high risk of stroke. The main role in etiopathogenesis is played by the left atrial appendage (LAA). As many as 95 % of thrombi in nonvalvular atrial fibrillation are located in the appendage. Prevention of stroke then consists in permanent anticoagulation which, however, has its limits and risks. An alternative method is the left atrial appendage occlusion. In our report, we would like to present a new possibility of the closure using the epicardial system AtriClip (AtriCure)...
2017: Vnitr̆ní Lékar̆ství
https://www.readbyqxmd.com/read/28220648/left-atrial-appendage-occlusion-fighting-the-dark-side-of-atrial-fibrillation
#2
EDITORIAL
Francesco Meucci, Carlo Di Mario
No abstract text is available yet for this article.
February 15, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28218217/efficacy-and-safety-of-the-watchman-left-atrial-appendage-system-for-stroke-prevention-in-chinese-patients-with-nonvalvular-atrial-fibrillation-a-single-center-prospective-observational-study
#3
Wei-Ping Huang, Yong-Hua Zhang, Lei He, Xi Su, Xin-Wei Yang, Zai-Xiong Guo
BACKGROUND: In patients with nonvalvular atrial fibrillation (NVAF), embolic stroke is thought to be associated with left atrial appendage (LAA) thrombi. The WATCHMAN LAA Occlusion Device has been shown to be noninferior to conventional oral anticoagulation with warfarin for stroke prevention in patients with NVAF. This study aimed to evaluate the procedural feasibility, safety and 12-month outcomes of the WATCHMAN LAA Occlusion Device in NVAF patients with high risk for stroke in China...
2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28215464/patients-with-intracranial-bleeding-and-atrial-fibrillation-treated-with-left-atrial-appendage-occlusion-results-from-the-amplatzer-cardiac-plug-registry
#4
Apostolos Tzikas, Xavier Freixa, Laura Llull, Sameer Gafoor, Samera Shakir, Heyder Omran, George Giannakoulas, Sergio Berti, Gennaro Santoro, Joelle Kefer, Adel Aminian, Steffen Gloekler, Ulf Landmesser, Jens Erik Nielsen-Kudsk, Ignacio Cruz-Gonzalez, Prapa Kanagaratnam, Fabian Nietlispach, Reda Ibrahim, Horst Sievert, Wolfgang Schillinger, Jai-Wun Park, Bernhard Meier, Haralampos Karvounis
BACKGROUND: In patients with non-valvular atrial fibrillation (NVAF), intracranial bleeding (ICB) constitutes a very challenging situation in which the rate of both ischemic and hemorrhagic events is increased. In these patients, left atrial appendage occlusion (LAAO) might represent a very valid alternative. OBJECTIVES: To investigate the procedural safety and long-term outcome of patients undergoing LAAO therapy due to previous ICB. METHODS: Data from the Amplatzer Cardiac Plug multicenter registry on 1047 consecutive patients were analyzed...
February 13, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28215062/left-atrial-appendage-occlusion-for-stroke-prevention-in-patients-with-atrial-fibrillation-a-systematic-review-and-network-meta-analysis-of-randomized-controlled-trials
#5
Hasib Hanif, Emilie P Belley-Cote, Abdullah Alotaibi, Nazari Dvirnik, Binod Neupane, Joseph Beyene, John W Eikelboom, David Holmes, Richard P Whitlock
INTRODUCTION: Atrial fibrillation (AF) is one of the leading causes of stroke. Risks associated with oral anticoagulation limit adherence to recommended therapy. Left atrial appendage (LAA) occlusion is a treatment alternative in patients with AF. We performed a network meta-analysis (NMA) of randomized trials evaluating the efficacy of LAA occlusion compared with oral anticoagulant, antiplatelet, and placebo for stroke prevention. We also assessed the impact of LAA occlusion on mortality, major bleeding, and operative time...
February 17, 2017: Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/28212133/potential-uselessness-and-futility-of-left-atrial-appendage-occlusion-and-patent-foramen-ovale-closure-in-cardioembolic-stroke
#6
Gian L Nicolosi
International guidelines indicate that interventional closure of left atrial appendage and patent foramen ovale may be considered in selected patients for stroke prevention. These procedures appear, however, from the published literature, at high risk of uselessness and futility in the single case, if not even capable to induce harm and adverse events. In fact, all reported systematic reviews and meta-analyses have not shown in a convincing manner the superiority of these procedures in stroke prevention, taking into account the occurrence of possible complications also, as compared with alternative medical treatment...
February 16, 2017: Journal of Cardiovascular Medicine
https://www.readbyqxmd.com/read/28198520/twelve-month-follow-up-of-left-atrial-appendage-occlusion-with-amplatzer-amulet
#7
Caroline Kleinecke, Jai-Wun Park, Martin Gödde, Konstantin Zintl, Steffen Schnupp, Johannes Brachmann
BACKGROUND: The Amplatzer Amulet (St. Jude Medical, Minneapolis, MN, USA) is a second generation Amplatzer device for left atrial appendage occlusion for stroke prophylaxis in patients with atrial fibrillation. This research sought to assess the clinical performance of the Amplatzer Amulet device and in follow up for 12 months. METHODS: In this single-center registry patients with atrial fibrillation and contraindication to oral anticoagulation underwent left atrial appendage occlusion (LAAO) with the Amplatzer Amulet device...
February 15, 2017: Cardiology Journal
https://www.readbyqxmd.com/read/28145040/device-associated-thrombus-formation-after-left-atrial-appendage-occlusion-a-systematic-review-of-events-reported-with-the-watchman-the-amplatzer-cardiac-plug-and-the-amulet
#8
Mathieu Lempereur, Adel Aminian, Xavier Freixa, Sameer Gafoor, Joelle Kefer, Apostolos Tzikas, Victor Legrand, Jacqueline Saw
OBJECTIVES: This study aimed to provide a systematic review of device-associated thrombosis (DAT) after left atrial appendage occlusion (LAAO) with the Watchman, Amplatzer Cardiac Plug, and Amulet devices. BACKGROUND: DAT is known as a complication of LAAO but data about its clinical impact is scarce. METHODS: A systematic review of studies evaluating the incidence, treatment and clinical implications of DAT from January 2008 to September 2015 was conducted...
February 1, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28129320/totally-endoscopic-robotic-left-atrial-appendage-closure-demonstrates-high-success-rate
#9
Alison F Ward, Robert M Applebaum, Nana Toyoda, Ans Fakiha, Peter J Neuburger, Jennie Ngai, Robert G Nampiaparampil, David W Yaffee, Didier F Loulmet, Eugene A Grossi
OBJECTIVE: In patients with atrial fibrillation, 90% of embolic strokes originate from the left atrial appendage (LAA). Successful exclusion of the LAA is associated with a lower stroke rate in patients with atrial fibrillation. Surgical oversewing of the LAA is often incomplete when evaluated with transesophageal echocardiogram (TEE). External closure techniques of suturing and stapling have also demonstrated high failure rates with persistent flow and large stumps. We hypothesized that the precise visualization of a robotic LAA closure (RLAAC) would result in superior closure rates...
January 2017: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
https://www.readbyqxmd.com/read/28121919/roles-of-real-time-three-dimensional-transesophageal-echocardiography-in-peri-operation-of-transcatheter-left-atrial-appendage-closure
#10
Qing Zhou, Hongning Song, Lan Zhang, Qing Deng, Jinling Chen, Bo Hu, Yijia Wang, Ruiqiang Guo
Left atrial appendage (LAA) closure is a new treatment option for the prevention of stroke in patients with nonvalvular atrial fibrillation (AF). Conventional 2-dimensional transesophageal echocardiography (2D TEE) has some limitations in the imaging assessment of LAA closure. Real-time 3-dimensional transesophageal echocardiography (RT-3D TEE) allows for detailed morphologic assessment of the LAA. In this study, we aim to determine the clinical values of RT-3D TEE in the periprocedure of LAA closure.Thirty-eight persistent or paroxysmal AF patients with indications for LAA closure were enrolled in this study...
January 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28057808/heartbeat-left-atrial-appendage-occlusion-for-stroke-prevention
#11
EDITORIAL
Catherine M Otto
No abstract text is available yet for this article.
January 15, 2017: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/28044988/feasibility-of-concomitant-mitraclip-and-left-atrial-appendage-occlusion
#12
Shingo Kuwata, Maurizio Taramasso, Michel Zuber, Gabor Suetsch, Adrian Attinger-Toller, David Wicki, Francesco Maisano, Fabian Nietlispach
AIMS: The aim of our study is to report our single center experience with concomitant MitraClip (MC) and left atrial appendage occlusion (LAAO) and to further assess feasibility, safety and short term outcome of such an approach. METHODS AND RESULTS: Twenty-five consecutive patients underwent MC with concomitant LAAO at our hospital (combined group). As a control group, 25 consecutive patients with atrial fibrillation (AF) undergoing standalone MC were selected...
January 3, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28012051/assessment-of-the-left-atrial-appendage-structure-and-morphology-comparison-of-real-time-three-dimensional-transesophageal-echocardiography-and-computed-tomography
#13
Wenjuan Bai, Zhongxiu Chen, Hong Tang, Hui Wang, Wei Cheng, Li Rao
In this study, the left atrial appendage (LAA) structure and morphology were assessed using real-time three-dimensional transesophageal echocardiography (RT3D-TEE) and enhanced cardiac computed tomography (CT) scanning, and the two measurements obtained using these different techniques were compared. Two hundred nonvalvular atrial fibrillation (NVAF) patients who were prepared to undergo radiofrequency ablation were enrolled, and 62 controls were enrolled prospectively. RT3D-TEE and CT were performed, and the following parameters were measured: LAA orifice diameter, area, depth, maximum volume, and emptying velocity...
December 23, 2016: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/27979034/interventional-left-atrial-appendage-closure-vs-novel-anticoagulation-agents-in-patients-with-atrial-fibrillation-indicated-for-long-term-anticoagulation-prague-17-study
#14
Pavel Osmancik, Petr Tousek, Dalibor Herman, Petr Neuzil, Pavel Hala, Josef Stasek, Ludek Haman, Petr Kala, Martin Poloczek, Marian Branny, Jan Chovancik, Pavel Cervinka, Jiri Holy, Vlastimil Vancura, Richard Rokyta, Milos Taborsky, Tomas Kovarnik, David Zemanek, Petr Peichl, Sarka Haskova, Jiri Jarkovsky, Petr Widimsky
: Atrial fibrillation (AF), with a prevalence of 1% to 2%, is the most common cardiac arrhythmia. Without antithrombotic treatment, the annual risk of a cardioembolic event is 5% to 6%. The source of a cardioembolic event is a thrombus, which is usually formed in the left atrial appendage (LAA). Prevention of cardioembolic events involves treatment with anticoagulant drugs: either vitamin K antagonists or, recently, novel oral anticoagulants (NOAC). The other (nonpharmacologic) option for the prevention of a cardioembolic event involves interventional occlusion of the LAA...
January 2017: American Heart Journal
https://www.readbyqxmd.com/read/27973336/transcatheter-left-atrial-appendage-occlusion-in-patients-with-atrial-fibrillation-and-a-high-bleeding-risk-using-aspirin-alone-for-post-implant-antithrombotic-therapy
#15
Kasper Korsholm, Kirsten Melgaard Nielsen, Jesper Møller Jensen, Henrik Kjærulf Jensen, Grethe Andersen, Jens Erik Nielsen-Kudsk
AIMS: To evaluate safety and efficacy of left atrial appendage occlusion (LAAO) with the Amplatzer Cardiac Plug (ACP) or Amulet using Aspirin (ASA) alone as post-implant antithrombotic treatment. METHODS AND RESULTS: Single-center, prospective, non-randomized study on LAAO with the ACP or Amulet in a consecutive cohort (n=110) treated by ASA alone post-implantation. Primary outcome was device-related thrombosis, while secondary outcomes were ischemic stroke or major bleeding...
December 15, 2016: EuroIntervention
https://www.readbyqxmd.com/read/27973328/a-comparison-of-two-dimensional-and-real-time-3d-transesophageal-echocardiography-and-angiography-for-assessing-the-left-atrial-appendage-anatomy-for-sizing-a-left-atrial-appendage-occlusion-system-impact-of-volume-loading
#16
Baravan Al-Kassou, Apostolos Tzikas, F Stock, F Neikes, A Völz, H Omran
No abstract text is available yet for this article.
December 15, 2016: EuroIntervention
https://www.readbyqxmd.com/read/27970001/tct-624-novel-integrated-3d-multi-detector-computed-tomography-and-fluoroscopy-fusion-for-left-atrial-appendage-occlusion-procedures
#17
Andrew Roy, Jerome Horvilleur, Bertrand Cormier, Maxime Cazalas, Leticia Fernandez-Lopez, Martina Patanè, Antoinette Neylon, Marco Spaziano, Fadi Sawaya, Erik Bouvier, Thomas Hovasse, Thierry Lefevre, Bernard Chevalier, Philippe Garot
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27969999/tct-625-percutaneous-left-atrial-appendage-occlusion-in-a-chinese-population-results-from-the-hong-kong-laao-registry
#18
Ngai Yin Chan, Chi Chung Choy, Kang Yin Lee, Leung Kwai Chan, Raymond Fung, Gabriel Yip, Anna Chan, Gary Shing Him Cheung, Simon Lam, Kin Lam Tsui
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27969995/tct-619-periprocedural-intracardiac-echocardiography-from-the-left-atrium-for-left-atrial-appendage-occlusion-with-the-amplatzer-cardiac-plugtm
#19
Zied Frikha, Ayoub El Hammiri, Jeannot Potvin, Jean-Marc Raymond, Jean-Bernard Masson
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27969994/tct-620-a-comparison-of-clinical-outcomes-between-triple-antithrombotic-therapy-versus-dual-antiplatelet-with-left-atrial-appendage-occlusion-in-patients-with-atrial-fibrillation-undergoing-drug-eluting-stent-implantation
#20
Seung Hun Lee, Jae Young Cho, Hyung Joon Joo, Jae Hyoung Park, Soonjun Hong, Cheol Woong Yu, Do Sun Lim
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
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