Fei He, Xinyi Mu, Yan Zhang, Yongheng Wang, Jianwei Geng, Yanqing Geng, Yidan Ma, Xin Yin, Rufei Gao, Xuemei Chen, Junlin He
Fenvalerate (FEN), a type II pyrethroid pesticide, finds extensive application in agriculture, graziery and public spaces for pest control, resulting in severe environmental pollution. As an environmental endocrine disruptor with estrogen-like activity, exposure to FEN exhibited adverse effects on ovarian functions. Additionally, the presence of the metabolite of FEN in women's urine shows a positive association with the risk of primary ovarian insufficiency (POI). In mammals, the primordial follicle pool established during the early life serves as a reservoir for storing all available oocytes throughout the female reproductive life...
March 18, 2024: Science of the Total Environment