Tim L Hamelink, Baran Ogurlu, Carolina C Pamplona, Johannes Castelein, Sigrid S Bennedsgaard, Haiyun Qi, Thomas Weiss, Veerle A Lantinga, Merel B F Pool, Christoffer Laustsen, Bente Jespersen, Henri G D Leuvenink, Steffen Ringgaard, Ronald J H Borra, Anna K Keller, Cyril Moers
INTRODUCTION: Normothermic machine perfusion (NMP) is increasingly considered for pre-transplant kidney quality assessment. However, fundamental questions about differences between in vivo and ex vivo renal function, as well as the impact of ischemic injury on ex vivo physiology, remain unanswered. This study utilized magnetic resonance imaging (MRI), alongside conventional parameters to explore differences between in vivo and ex vivo renal function and the impact of warm ischemia on a kidney's behavior ex vivo...
April 12, 2024: American Journal of Transplantation