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https://www.readbyqxmd.com/read/28430956/achieving-high-reliability-in-histology-%C3%A2-an-improvement-series-to-reduce-errors
#1
Yael K Heher, Yigu Chen, Sergey Pyatibrat, Edward Yoon, Jeffrey D Goldsmith, Kenneth E Sands
Objectives: Despite sweeping medical advances in other fields, histology processes have by and large remained constant over the past 175 years. Patient label identification errors are a known liability in the laboratory and can be devastating, resulting in incorrect diagnoses and inappropriate treatment. The objective of this study was to identify vulnerable steps in the histology workflow and reduce the frequency of labeling errors (LEs). Methods: In this 36-month study period, a numerical step key (SK) was developed to capture LEs...
November 1, 2016: American Journal of Clinical Pathology
https://www.readbyqxmd.com/read/28429776/global-distribution-of-particle-phase-state-in-atmospheric-secondary-organic-aerosols
#2
Manabu Shiraiwa, Ying Li, Alexandra P Tsimpidi, Vlassis A Karydis, Thomas Berkemeier, Spyros N Pandis, Jos Lelieveld, Thomas Koop, Ulrich Pöschl
Secondary organic aerosols (SOA) are a large source of uncertainty in our current understanding of climate change and air pollution. The phase state of SOA is important for quantifying their effects on climate and air quality, but its global distribution is poorly characterized. We developed a method to estimate glass transition temperatures based on the molar mass and molecular O:C ratio of SOA components, and we used the global chemistry climate model EMAC with the organic aerosol module ORACLE to predict the phase state of atmospheric SOA...
April 21, 2017: Nature Communications
https://www.readbyqxmd.com/read/28429510/mixing-of-water-masses-caused-by-a-drifting-iceberg-affects-bacterial-activity-community-composition-and-substrate-utilization-capability-in-the-southern-ocean
#3
Julie Dinasquet, Inga Richert, Ramiro Logares, Patricia Yager, Stefan Bertilsson, Lasse Riemann
The number of icebergs produced from ice-shelf disintegration has increased over the past decade in Antarctica. These drifting icebergs mix the water column, influence stratification and nutrient condition, and can affect local productivity and food web composition. Data on whether icebergs affect bacterioplankton function and composition are scarce, however. We assessed the influence of iceberg drift on bacterial community composition and on their ability to exploit carbon substrates during summer in the coastal Southern Ocean...
April 21, 2017: Environmental Microbiology
https://www.readbyqxmd.com/read/28429262/movement-of-a-female-polar-bear-ursus-maritimus-in-the-kara-sea-during-the-summer-sea-ice-break-up
#4
V V Rozhnov, N G Platonov, S V Naidenko, I N Mordvintsev, E A Ivanov
The polar bear movement trajectory in relation to onset date of the sea-ice break-up was studied in the coastal zone of the Taimyr Peninsula, eastern part of the Kara Sea, using as an example a female polar bear tagged by a radio collar with an Argos satellite transmitter. Analysis of the long-term pattern of ice melting and tracking, by means of satellite telemetry, of the female polar bear who followed the ice-edge outgoing in the north-eastern direction (in summer 2012) suggests that direction of the polar bear movement depends precisely on the direction of the sea-ice cover break-up...
January 2017: Doklady Biological Sciences: Proceedings of the Academy of Sciences of the USSR, Biological Sciences Sections
https://www.readbyqxmd.com/read/28428938/effects-of-supplementation-with-antifreeze-proteins-on-the-follicular-integrity-of-vitrified-warmed-mouse-ovaries-comparison-of-two-types-of-antifreeze-proteins-alone-and-in-combination
#5
Min Kyung Kim, Hyun Sun Kong, Hye Won Youm, Byung Chul Jee
OBJECTIVE: The aim of this study was to analyze the effect of supplementing vitrification and warming solutions with two types of antifreeze proteins (AFPs) and the combination thereof on the follicular integrity of vitrified-warmed mouse ovaries. METHODS: Ovaries (n=154) were obtained from 5-week-old BDF1 female mice (n=77) and vitrified using ethylene glycol and dimethyl sulfoxide with the supplementation of 10 mg/mL of Flavobacterium frigoris ice-binding protein (FfIBP), 10 mg/mL of type III AFP, or the combination thereof...
March 2017: Clinical and Experimental Reproductive Medicine
https://www.readbyqxmd.com/read/28426711/proinsulin-is-stable-at-room-temperature-for-24-hours-in-edta-a-clinical-laboratory-analysis-adapt-3
#6
Jane Davidson, Timothy McDonald, Calum Sutherland, Mohammod Mostazir, Lidy VanAalten, Terence Wilkin
AIMS: Reference laboratories advise immediate separation and freezing of samples for the assay of proinsulin, which limit its practicability for smaller centres. Following the demonstration that insulin and C-peptide are stable in EDTA at room temperature for at least 24hours, we undertook simple stability studies to establish whether the same might apply to proinsulin. METHODS: Venous blood samples were drawn from six adult women, some fasting, some not, aliquoted and assayed immediately and after storage at either 4°C or ambient temperature for periods from 2h to 24h...
2017: PloS One
https://www.readbyqxmd.com/read/28426377/development-of-the-sports-organization-concussion-risk-assessment-tool-socrat
#7
A Yeung, V Munjal, N Virji-Babul
OBJECTIVE: In this paper, we describe the development of a novel tool-the Sports Organization Concussion Risk Assessment Tool (SOCRAT)-to assist sport organizations in assessing the overall risk of concussion at a team level by identifying key risk factors. METHODS: We first conducted a literature review to identify risk factors of concussion using ice hockey as a model. We then developed an algorithm by combining the severity and the probability of occurrence of concussions of the identified risk factors by adapting a risk assessment tool commonly used in engineering applications...
2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28426303/measures-of-local-segregation-for-monitoring-health-inequities-by-local-health-departments
#8
Nancy Krieger, Pamela D Waterman, Neelesh Batra, Johnna S Murphy, Daniel P Dooley, Snehal N Shah
OBJECTIVES: To assess the use of local measures of segregation for monitoring health inequities by local health departments. METHODS: We analyzed preterm birth and premature mortality (death before the age of 65 years) rates for Boston, Massachusetts, for 2010 to 2012, using the Index of Concentration at the Extremes (ICE) and the poverty rate at both the census tract and neighborhood level. RESULTS: For premature mortality at the census tract level, the rate ratios comparing the worst-off and best-off terciles were 1...
April 20, 2017: American Journal of Public Health
https://www.readbyqxmd.com/read/28426005/antarctic-ice-shelf-potentially-stabilized-by-export-of-meltwater-in-surface-river
#9
Robin E Bell, Winnie Chu, Jonathan Kingslake, Indrani Das, Marco Tedesco, Kirsty J Tinto, Christopher J Zappa, Massimo Frezzotti, Alexandra Boghosian, Won Sang Lee
Meltwater stored in ponds and crevasses can weaken and fracture ice shelves, triggering their rapid disintegration. This ice-shelf collapse results in an increased flux of ice from adjacent glaciers and ice streams, thereby raising sea level globally. However, surface rivers forming on ice shelves could potentially export stored meltwater and prevent its destructive effects. Here we present evidence for persistent active drainage networks-interconnected streams, ponds and rivers-on the Nansen Ice Shelf in Antarctica that export a large fraction of the ice shelf's meltwater into the ocean...
April 19, 2017: Nature
https://www.readbyqxmd.com/read/28425996/glaciology-ice-shelf-stability-questioned
#10
Alison Banwell
No abstract text is available yet for this article.
April 19, 2017: Nature
https://www.readbyqxmd.com/read/28425995/widespread-movement-of-meltwater-onto-and-across-antarctic-ice-shelves
#11
Jonathan Kingslake, Jeremy C Ely, Indrani Das, Robin E Bell
Surface meltwater drains across ice sheets, forming melt ponds that can trigger ice-shelf collapse, acceleration of grounded ice flow and increased sea-level rise. Numerical models of the Antarctic Ice Sheet that incorporate meltwater's impact on ice shelves, but ignore the movement of water across the ice surface, predict a metre of global sea-level rise this century in response to atmospheric warming. To understand the impact of water moving across the ice surface a broad quantification of surface meltwater and its drainage is needed...
April 19, 2017: Nature
https://www.readbyqxmd.com/read/28425458/anatomy-of-terminal-moraine-segments-and-implied-lake-stability-on-ngozumpa-glacier-nepal-from-electrical-resistivity-tomography-ert
#12
Sarah S Thompson, Bernd Kulessa, Douglas I Benn, Jordan R Mertes
Moraine-dammed lakes at debris-covered glaciers are becoming increasingly common and pose significant outburst flood hazards if the dam is breached. While moraine subsurface structure and internal processes are likely to influence dam stability, only few sites have so far been investigated. We conducted electrical resistivity tomography (ERT) surveys at two sites on the terminal moraine complex of the Ngozumpa Glacier, Nepal, to aid assessment of future terminus stability. The resistivity signature of glacier ice at the site (100-15 kΩ m) is more consistent with values measured from cold glacier ice and while this may be feasible, uncertainties in the data inversion introduce ambiguity to this thermal interpretation...
April 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28424314/muscle-biochemistry-of-a-pelagic-delphinid-stenella-longirostris-longirostris-insight-into-fishery-induced-separation-of-mothers-and-calves
#13
Shawn R Noren, Kristi West
The length of time required for postnatal maturation of the locomotor muscle (longissimus dorsi) biochemistry [myoglobin (Mb) content and buffering capacity] in marine mammals typically varies with nursing duration, but it can be accelerated by species-specific behavioral demands, such as deep-diving and sub-ice transit. We examined how the swimming demands of a pelagic lifestyle influence postnatal maturation of Mb and buffering capacity in spinner dolphins (Stenella longirostris longirostris). Mb content of newborn (1...
April 15, 2017: Journal of Experimental Biology
https://www.readbyqxmd.com/read/28423285/the-epidemiology-of-high-ankle-sprains-in-national-collegiate-athletic-association-sports
#14
Timothy C Mauntel, Erik A Wikstrom, Karen G Roos, Aristarque Djoko, Thomas P Dompier, Zachary Y Kerr
BACKGROUND: Ankle sprains are among the most common injuries experienced by collegiate athletes. The type of ankle sprain is rarely differentiated in epidemiological studies. This differentiation is necessary, as each ankle sprain type has a unique injury mechanism and recovery period. High ankle sprains commonly result in long recovery periods. Thus, a further examination of the epidemiology of high ankle sprains is warranted. PURPOSE: To describe the epidemiology of high ankle sprains in National Collegiate Athletic Association (NCAA) sports during the 2009/2010-2014/2015 academic years...
April 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28422604/examination-of-intramuscular-and-skin-temperature-decreases-produced-by-the-powerplay-intermittent-compression-cryotherapy
#15
Jennifer Ostrowski
CONTEXT: Previous research has found ice bags are more effective at lowering intramuscular temperature than gel packs. Recent studies have evaluated intramuscular temperature cooling decreases of ice bag versus GameReady, and with the PowerPlay system wetted ice bag inserts, however intramuscular decreases elicited by PowerPlay with the standard frozel gel pack inserts have not been examined. OBJECTIVE: Evaluate rate and magnitude of cooling using PowerPlay with frozen gel pack option (PP-gel), PowerPlay with wetted ice bag option (PP-ice), and control (no treatment) on skin and intramuscular temperature (2cm sub-adipose)...
April 19, 2017: Journal of Sport Rehabilitation
https://www.readbyqxmd.com/read/28422434/rat-hindlimb-cryopreservation-and-transplantation-a-step-towards-organ-banking
#16
Amir Arav, Or Friedman, Yehudit Natan, Eyal Gur, Nir Shani
In 2016 over 5 million reconstructive procedures were performed in the USA. The recent successes of clinical vascularized composite allotransplantations (VCA), hand and face transplantations included, established the tremendous potential of these life-enhancing reconstructions. Nevertheless, Due to limited availability and lifelong immunosuppression, application is limited. Long term banking of composite transplants may increase the availability of esthetically compatible parts with partial or complete HLA matching, reducing the risk of rejection and the immunosuppressive burden...
April 19, 2017: American Journal of Transplantation
https://www.readbyqxmd.com/read/28422184/sea-level-proxies-in-holocene-raised-beach-ridge-deposits-greenland-revealed-by-ground-penetrating-radar
#17
Lars Nielsen, Mette Bendixen, Aart Kroon, Mikkel Ulfeldt Hede, Lars B Clemmensen, Ronny Weβling, Bo Elberling
Identification of sea-level proxies is important for reconstruction of past sea-level variation. Methods for reconstructing Holocene relative sea-level curves are crucial for quantification of the impact of Greenland ice thickness variation on global sea level and vertical land movement. Arctic beach ridges constitute important potential archives of sea-level variation. However, their surface morphology may have undergone modification since deposition due to freezing/thawing processes and erosion, and their morphology may therefore not be trustworthy for sea-level reconstruction...
April 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28421914/seeing-the-forest-but-not-the-trees-heterogeneity-in-community-size-effects-in-canadian-ice-hockey-players
#18
N Wattie, J Schorer, J Baker
The community size effect (or birthplace effect) suggests that high-performance athletes are less likely to emerge from regions with population sizes that are very small or very large. However, previous research on elite Canadian ice hockey players has not considered the influence of intra-national regional variation of population distributions with respect to community size effects. Therefore, the purpose of the current study was to test the heterogeneity of the community size effect between Canadian National Hockey League draftees (2000-2014: n = 1505), from 7 provincial regions within Canada (i...
April 19, 2017: Journal of Sports Sciences
https://www.readbyqxmd.com/read/28420828/y-tzp-zirconia-regeneration-firing-microstructural-and-crystallographic-changes-after-grinding
#19
Daniel Patrick Obelenis Ryan, Laiza Maria Grassi Fais, Selma Gutierrez Antonio, Gabriel Rodrigues Hatanaka, Lucas Miguel Candido, Ligia Antunes Pereira Pinelli
This study evaluated microstructural and crystallographic phase changes after grinding (G) and regeneration firing/anneling (R) of Y-TZP ceramics. Thirty five bars (Lava(TM) and Ice Zirkon) were divided: Y-TZP pre-sintered, control (C), regeneration firing (R), dry grinding (DG), dry grinding+regeneration firing (DGR), wet grinding (WG) and wet grinding+regeneration firing (WGR). Grinding was conducted using a diamond bur and annealing at 1,000°C. The microstructure was analyzed by SEM and the crystalline phases by X-ray diffraction (XRD)...
April 18, 2017: Dental Materials Journal
https://www.readbyqxmd.com/read/28419666/microbial-ecology-of-mountain-glacier-ecosystems-biodiversity-ecological-connections-and-implications-of-a-warming-climate
#20
REVIEW
Scott Hotaling, Eran Hood, Trinity L Hamilton
Glacier ecosystems are teeming with life on, beneath, and to a lesser degree, within their icy masses. This conclusion largely stems from polar research, with less attention paid to mountain glaciers that overlap environmentally and ecologically with their polar counterparts in some ways, but diverge in others. One difference lies in the susceptibility of mountain glaciers to the near-term threat of climate change, as they tend to be much smaller in both area and volume. Moreover, mountain glaciers are typically steeper, more dependent upon basal sliding for movement, and experience higher seasonal precipitation...
April 17, 2017: Environmental Microbiology
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