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https://www.readbyqxmd.com/read/28087266/assessment-of-sex-differences-in-body-composition-among-adolescents-with-anorexia-nervosa
#1
Jason M Nagata, Neville H Golden, Rebecka Peebles, Jin Long, Stuart B Murray, Mary B Leonard, Jennifer L Carlson
PURPOSE: To compare deficits in fat mass (FM) and lean body mass (LM) among male and female adolescents with anorexia nervosa (AN) and to identify other covariates associated with body composition. METHODS: We retrospectively reviewed electronic medical records of all subjects aged 9-20 years with a Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition diagnosis of AN and dual-energy x-ray absorptiometry scans after initial evaluation at Stanford between March 1997 and February 2011...
January 11, 2017: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/28079570/re-incidental-gallbladder-cancer-visualized-from-posttreatment-131i-whole-body-scan
#2
Chanika Sritara
No abstract text is available yet for this article.
January 10, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28072622/170tm-edtmp-a-prospective-alternative-of-89srcl2-for-theranostic-treatment-of-metastatic-bone-pain
#3
Tapas Das, Ajit Shinto, Koramadai Karuppuswamy Kamaleshwaran, Sharmila Banerjee
We have earlier reported the potential of Tm-EDTMP as an alternative cost-effective radiopharmaceutical of SrCl2 for bone pain palliation application. Encouraging results obtained in the radiochemical studies and biological evaluations in animal model have prompted us to initiate the clinical study to evaluate the potential of Tm-EDTMP in human cancer patients. The serial scintigraphic images represent the whole-body scans of a patient (68 years old woman) with skeletal metastases of carcinoma of the breast origin recorded after administering 370 MBq (10 mCi) of Tm-EDTMP at different post-administration time points along with the pre-therapy images recorded with Tc-MDP in the same patient...
January 9, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28062597/the-effect-of-susceptibility-artifacts-related-to-metal-implants-on-adjacent-lesion-assessment-in-simultaneous-tof-pet-mr
#4
Hanna Svirydenka, Gaspar Delso, Felipe DE Galiza Barbosa, Martin W Huellner, Helen Davison, Stefano Fanti, Patrick Veit-Haibach, Edwin Ter Voert
OBJECTIVE: Metal implants could affect the attenuation correction (AC) in positron emission tomography (PET)/magnetic resonance (MR) imaging. The purpose of this study is to evaluate the effect of susceptibility artifacts related to metal implants on adjacent metabolically active lesions in clinical simultaneous PET/MR scanning for both time-of-flight (TOF) and non-TOF reconstructed PET images. METHODS: We included 27 patients without implants, but with confirmed 2-deoxy-2-(18)F-fluoro-D-glucose ((18)F-FDG) avid lesions adjacent to common implant locations...
January 6, 2017: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/28062546/the-clinical-importance-of-quantifying-fat-distribution-during-androgen-deprivation
#5
Stephen John Foulkes, Robin M Daly, Steve Fraser
Androgen deprivation therapy (ADT) is now considered a mainstay in the treatment of metastatic and locally advanced prostate cancer (PCa). Despite well-established benefits of ADT in relation to overall survival, this treatment has been associated with a number of adverse effects, particularly with regard to key cardiometabolic risk factors including the development of insulin resistance, dyslipidaemia and increases in total and regional fat mass. In non-ADT populations, increased levels of visceral adipose tissue (VAT) are thought to be a key mediator of the increased cardiometabolic risk associated with weight gain, but this has received limited attention in men treated with ADT...
January 6, 2017: Endocrine-related Cancer
https://www.readbyqxmd.com/read/28054143/a-low-cost-mr-compatible-ergometer-to-assess-post-exercise-phosphocreatine-recovery-kinetics
#6
Niels D Naimon, Jerzy Walczyk, James S Babb, Oleksandr Khegai, Xuejiao Che, Leeor Alon, Ravinder R Regatte, Ryan Brown, Prodromos Parasoglou
OBJECTIVE: To develop a low-cost pedal ergometer compatible with ultrahigh (7 T) field MR systems to reliably quantify metabolic parameters in human lower leg muscle using phosphorus magnetic resonance spectroscopy. MATERIALS AND METHODS: We constructed an MR compatible ergometer using commercially available materials and elastic bands that provide resistance to movement. We recruited ten healthy subjects (eight men and two women, mean age ± standard deviation: 32...
January 4, 2017: Magma
https://www.readbyqxmd.com/read/28054124/-severe-blunt-thoracic-trauma-caused-by-ski-collision
#7
S J Lochner, M Scherr, M Perl, C Grove
An approximately 25-year-old skier collided in a ski-run intersection. At high speed, he first hit another skier and then smashed into a snow cannon. He died from his injuries a short time later in hospital. A whole-body CT scan was conducted under resuscitation conditions, which was followed by an autopsy. The investigation revealed a severe blunt thoracic trauma as cause of death. The detailed analysis was the result of the combination of the two methods of investigation, CT scan and autopsy. The methods complemented each other effectively and allowed for a detailed presentation of the injury pattern...
January 4, 2017: Der Unfallchirurg
https://www.readbyqxmd.com/read/28052064/validity-and-intra-observer-reliability-of-three-dimensional-scanning-compared-to-conventional-anthropometry-for-children-and-adolescents-from-a-population-based-cohort-study
#8
Fabian Glock, Mandy Vogel, Stephanie Naumann, Andreas Kuehnapfel, Markus Scholz, Andreas Hiemisch, Toralf Kirsten, Kristin Rieger, Antje Koerner, Markus Loeffler, Wieland Kiess
BackgroundConventional anthropometric measurements are time consuming and require well trained medical staff. To use three-dimensional whole body laser scanning in daily clinical work, validity and reliability have to be confirmed.MethodsWe compared a whole body laser scanner to conventional anthropometry in a group of 473 children and adolescents from the Leipzig Research Centre for Civilization Diseases (LIFE-Child). Concordance correlation coefficients (CCC) were calculated separately for sex, weight and age to assess validity...
January 4, 2017: Pediatric Research
https://www.readbyqxmd.com/read/28049718/patterns-of-organelle-ontogeny-through-a-cell-cycle-revealed-by-whole-cell-reconstructions-using-3d-electron-microscopy
#9
Louise Hughes, Samantha Borrett, Katie Towers, Tobias Starborg, Sue Vaughan
The major mammalian bloodstream form of the African sleeping sickness parasite Trypanosoma brucei multiplies rapidly and it is important to understand how these cells divide. Organelle inheritance involves complex spatiotemporal re-arrangements to ensure correct distribution to daughter cells. Serial block face scanning electron microscopy (SBF-SEM) was used to reconstruct whole individual cells at different stages of the cell cycle to give an unprecedented temporal, spatial and quantitative view of organelle division, inheritance and abscission in a eukaryotic cell...
January 3, 2017: Journal of Cell Science
https://www.readbyqxmd.com/read/28048696/mo-fg-campus-iep3-01-evaluation-of-specific-absorption-rate-and-temperature-increase-induced-by-artificial-medical-implants-during-mri-scan
#10
Y Seo
PURPOSE: Heating of patients or burning of biological tissues around medical implants by RF power during MRI scan is a significant patient safety concern. The purpose of this study is to not only measure SAR values, but also RF-induced temperature elevation due to artificial hip joints during MRI scans. METHODS: SAR measurement experiment was performed on three discrete manufacturers at 1.5 and 3T. Three MRI RF sequences (T1w TSE, T2w inversion recovery, and T2w TSE) with imaging parameters were selected...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048576/we-h-207a-04-impact-of-lesion-location-on-the-repeatability-of-18f-naf-pet-ct
#11
C Lin, T Perk, S Harmon, S Perlman, G Liu, R Jeraj
PURPOSE: Quantifying the repeatability of imaging biomarkers is critical for assessing therapeutic response. While (18) F-NaF PET/CT has shown to be a repeatable imaging method, research has not shown which factors may influence its repeatability. The purpose of this study was to evaluate whether the location of the lesion impacts the repeatability of quantitative (18) F-NaF PET-derived SUV metrics. METHODS: Metastatic castrate-resistant prostate cancer patients with multiple bone lesions received whole-body test-retest NaF PET/CT scans...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048568/th-ab-207a-02-do-low-kvp-ct-scans-increase-the-dose-received-by-superficial-organs
#12
X Li, F Dong, A Primak, P Segars, B Herts
PURPOSE: Tube voltages below 120 kVp are increasingly used in clinical CT. There are concerns that dose to superficial organs such as skin, thyroid, and breasts may be elevated at a low-kVp setting. Our purpose was to investigate the effect of low-kVp imaging on the dose received by deep-seated and superficial organs as well as the effective dose. METHODS: Three computational patient models were included. They represented normal-weight, overweight, and obese adult females (BMI: 20-42)...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048364/we-fg-207a-01-introduction-to-dedicated-breast-ct-early-studies
#13
S Vedantham
: Mammography-based screening has been a valuable imaging tool for the early detection of non-palpable lesions and has contributed to significant reduction in breast cancer associated mortality. However, the breast imaging community recognizes that mammography is not ideal, and in particular is inferior for women with dense breasts. Also, the 2-D projection of a 3-D organ results in tissue superposition contributing to false-positives. The sensitivity of mammography is breast-density dependent...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048035/mo-fg-campus-iep3-02-gradient-nonlinearity-calibration-and-correction-for-full-volume-imaging-of-a-compact-asymmetric-mri-gradient-system
#14
S Tao, J Trzasko, Y Shu, P Weavers, J Gunter, J Huston, S Lee, E Tan, M Bernstein
PURPOSE: Due to engineering limitations, the spatial encoding gradient fields generated by an MRI scanner are inherently nonlinear and images must undergo geometric correction prior to display. The gradient nonlinearity (GNL) of a conventional symmetric whole-body gradient is typically characterized using a spherical harmonic polynomial (SHP) expansion of magnetic gradient fields with up to fifth-order terms. Only odd-order terms are required due to design symmetry (i.e., 3rd/5th-order)...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047717/we-fg-207a-02-why-we-need-breast-ct-clinical-perspective
#15
A O'Connell
: Mammography-based screening has been a valuable imaging tool for the early detection of non-palpable lesions and has contributed to significant reduction in breast cancer associated mortality. However, the breast imaging community recognizes that mammography is not ideal, and in particular is inferior for women with dense breasts. Also, the 2-D projection of a 3-D organ results in tissue superposition contributing to false-positives. The sensitivity of mammography is breast-density dependent...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047652/su-f-sps-07-magnetic-resonance-spectroscopy-findings-in-early-phase-psychosis
#16
A Wright, R Ma, T Hummer, M Francis, N Mehdiyoun, U Dydak, A Breier
PURPOSE: Schizophrenia is a psychiatric disorder characterized by disordered thoughts, abnormal social behaviors, flat affect, and auditory or visual hallucinations. The current study aims to investigate alterations in brain metabolism in patients near the onset of psychosis (early-phase psychosis, EPP), to characterize abnormalities during the early stages of schizophrenia. To this end, we used magnetic resonance imaging (MRI) and spectroscopy (MRS) to measure metabolite levels and subsequently monitor the effect of treatment with N-acetylcysteine (NAC)...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047623/su-f-r-13-decoding-18f-fdg-uptake-heterogeneity-for-primary-and-lymphoma-tumors-by-using-texture-analysis-in-pet-images
#17
C Ma, Y Yin
PURPOSE: To explore 18F-FDG uptake heterogeneity of primary tumor and lymphoma tumor by texture features of PET image and quantify the heterogeneity difference between primary tumor and lymphoma tumor. METHODS: 18 patients with primary tumor and lymphoma tumor in lung cancer were enrolled. All patients underwent whole-body 18F-FDG PET/CT scans before treatment. Texture features, based on Gray-level Co-occurrence Matrix, second and high order matrices are extracted from code using MATLAB software to quantify 18F-FDG uptake heterogeneity...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047573/su-g-brb-10-new-generation-of-high-frame-rate-and-high-spatial-resolution-epid-qa-system-for-full-body-mlc-based-robotic-radiosurgery
#18
B Han, L Xing, L Wang
PURPOSE: To systematically investigate an ultra-high spatial-resolution amorphous silicon flat-panel electronic portal imaging device (EPID) for MLC-based full-body robotic radiosurgery geometric and dosimetric quality assurance (QA). METHODS: The high frame-rate and ultra-high spatial resolution EPID is an outstanding detector for measuring profiles, MLC-shaped radiosurgery field aperture verification, and small field dosimetry. A Monte Carlo based technique with a robotic linac specific response and calibration is developed to convert a raw EPID-measured image of a radiosurgery field into water-based dose distribution...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047572/we-fg-207b-07-feasibility-of-low-dose-lung-cancer-screening-with-a-whole-body-photon-counting-ct-first-human-results
#19
R Symons, T Cork, L Folio, D Bluemke, A Pourmorteza
PURPOSE: To evaluate the feasibility of using a whole-body photon counting detector (PCD) CT scanner for low dose lung cancer screening compared to a conventional energy integrating detector (EID) system. METHODS: Radiation dose-matched EID and PCD scans of the COPDGene 2 phantom and 2 human volunteers were acquired. Phantom images were acquired at different radiation dose levels (CTDIvol: 3.0, 1.5, and 0.75 mGy) and different tube voltages (120, 100, and 80 kVp), while human images were acquired at vendor recommended low-dose lung cancer screening settings...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047520/we-fg-207a-05-dedicated-breast-ct-as-a-diagnostic-imaging-tool-physics-and-clinical-feasibility
#20
A Karellas
: Mammography-based screening has been a valuable imaging tool for the early detection of non-palpable lesions and has contributed to significant reduction in breast cancer associated mortality. However, the breast imaging community recognizes that mammography is not ideal, and in particular is inferior for women with dense breasts. Also, the 2-D projection of a 3-D organ results in tissue superposition contributing to false-positives. The sensitivity of mammography is breast-density dependent...
June 2016: Medical Physics
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