keyword
https://read.qxmd.com/read/38521646/multidisciplinary-consensus-on-the-management-of-non-invasive-respiratory-support-in-the-covid-19-patient
#21
Manel Luján, César Cinesi Gómez, Oscar Peñuelas, Carlos Ferrando, Sarah Béatrice Heili-Frades, José Manuel Carratalá Perales, Arantxa Mas, Javier Sayas Catalán, Olga Mediano, Oriol Roca, Javier García Fernández, Antonio González Varela, Gonzalo Sempere Montes, Gemma Rialp Cervera, Gonzalo Hernández, Teresa Millán, Miquel Ferrer Monreal, Carlos Egea Santaolalla
Acute respiratory failure due to COVID-19 pneumonia often requires a comprehensive approach that includes non-pharmacological strategies such as non-invasive support (including positive pressure modes, high flow therapy or awake proning) in addition to oxygen therapy, with the primary goal of avoiding endotracheal intubation. Clinical issues such as determining the optimal time to initiate non-invasive support, choosing the most appropriate modality (based not only on the acute clinical picture but also on comorbidities), establishing criteria for recognition of treatment failure and strategies to follow in this setting (including palliative care), or implementing de-escalation procedures when improvement occurs are of paramount importance in the ongoing management of severe COVID-19 cases...
March 4, 2024: Archivos de Bronconeumología
https://read.qxmd.com/read/38520923/towards-optimal-design-of-patient-isolation-units-in-emergency-rooms-to-prevent-airborne-virus-transmission-from-computational-fluid-dynamics-to-data-driven-modeling
#22
JOURNAL ARTICLE
Jong Hyeon Lee, Jae Woo Shim, Min Hyuk Lim, Changhoon Baek, Byoungjun Jeon, Minwoo Cho, Sungwoo Park, Dong Hyun Choi, Byeong Soo Kim, Dan Yoon, Young Gyun Kim, Seung Yeon Cho, Kyung-Min Lee, Myoung-Souk Yeo, Hangman Zo, Sang Do Shin, Sungwan Kim
BACKGROUND: Patient isolation units (PIUs) can be an effective method for effective infection control. Computational fluid dynamics (CFD) is commonly used for PIU design; however, optimizing this design requires extensive computational resources. Our study aims to provide data-driven models to determine the PIU settings, thereby promoting a more rapid design process. METHOD: Using CFD simulations, we evaluated various PIU parameters and room conditions to assess the impact of PIU installation on ventilation and isolation...
March 16, 2024: Computers in Biology and Medicine
https://read.qxmd.com/read/38519374/clinical-features-and-disease-progression-of-elderly-patients-at-the-icu-setting
#23
JOURNAL ARTICLE
Raquel Rodríguez-García, Loreto González-Lamuño, Mario Santullano, Beatriz Martín-Carro, Jose Luis Fernández-Martín, Maria Del Carmen Cienfuegos Basanta, Lorena Forcelledo, Carmen Palomo Antequera
OBJECTIVE: To describe and characterize a cohort of octogenarian patients admitted to the ICU of the University Central Hospital of Asturias (HUCA). DESIGN: Retrospective, observational and descriptive study of 14 months' duration. SETTING: Cardiac and Medical intensive care units (ICU) of the HUCA (Oviedo). PARTICIPANTS: Patients over 80 years old who were admitted to the ICU for more than 24 h. INTERVENTIONS: None...
March 21, 2024: Medicina intensiva
https://read.qxmd.com/read/38513675/association-of-active-mobilisation-variables-with-adverse-events-and-mortality-in-patients-requiring-mechanical-ventilation-in-the-intensive-care-unit-a-systematic-review-and-meta-analysis
#24
JOURNAL ARTICLE
Michelle Paton, Sarah Chan, Ary Serpa Neto, Claire J Tipping, Anne Stratton, Rebecca Lane, Lorena Romero, Tessa Broadley, Carol L Hodgson
BACKGROUND: Mobilisation during critical illness is now included in multiple clinical practice guidelines. However, a large, randomised trial and systematic review have recently identified an increased probability of adverse events and mortality in patients who received early active mobilisation in the intensive care unit (ICU). We aimed to determine the effects of mobilisation compared with usual care on adverse events and mortality in an acute ICU setting. In subgroup analyses, we specifically aimed to investigate possible sources of harm, including the timing and duration of mobilisation achieved, ventilation status, and admission diagnosis...
March 18, 2024: Lancet Respiratory Medicine
https://read.qxmd.com/read/38513567/outcomes-associated-with-ventilator-associated-events-vae-respiratory-infections-vari-pneumonia-vap-and-tracheobronchitis-vat-in-ventilated-pediatric-icu-patients-a-multicentre-prospective-cohort-study
#25
JOURNAL ARTICLE
Yolanda Peña-López, María Slocker-Barrio, Juan-Carlos de-Carlos-Vicente, Marta Serrano-Megías, Iolanda Jordán-García, Jordi Rello
OBJECTIVES: An objective categorization of respiratory infections based on outcomes is an unmet clinical need. Ventilator-associated pneumonia and tracheobronchitis remain used in clinical practice, whereas ventilator-associated events (VAE) are limited to surveillance purposes. RESEARCH METHODOLOGY/DESIGN: This was a secondary analysis from a multicentre observational prospective cohort study. VAE were defined as a sustained increase in minimum Oxygen inspired fraction (FiO2) and/or Positive end-expiratory pressures (PEEP) of ≥ 0...
March 19, 2024: Intensive & Critical Care Nursing: the Official Journal of the British Association of Critical Care Nurses
https://read.qxmd.com/read/38512544/determinants-of-acute-kidney-injury-during-high-power-mechanical-ventilation-secondary-analysis-from-experimental-data
#26
JOURNAL ARTICLE
Simone Gattarello, Fabio Lombardo, Federica Romitti, Rosanna D'Albo, Mara Velati, Isabella Fratti, Tommaso Pozzi, Rosmery Nicolardi, Antonio Fioccola, Mattia Busana, Francesca Collino, Peter Herrmann, Luigi Camporota, Michael Quintel, Onnen Moerer, Leif Saager, Konrad Meissner, Luciano Gattinoni
BACKGROUND: The individual components of mechanical ventilation may have distinct effects on kidney perfusion and on the risk of developing acute kidney injury; we aimed to explore ventilatory predictors of acute kidney failure and the hemodynamic changes consequent to experimental high-power mechanical ventilation. METHODS: Secondary analysis of two animal studies focused on the outcomes of different mechanical power settings, including 78 pigs mechanically ventilated with high mechanical power for 48 h...
March 21, 2024: Intensive Care Medicine Experimental
https://read.qxmd.com/read/38512359/estimation-of-the-transpulmonary-pressure-from-the-central-venous-pressure-in-mechanically-ventilated-patients
#27
JOURNAL ARTICLE
Federico Franchi, Emanuele Detti, Alberto Fogagnolo, Savino Spadaro, Gabriele Cevenini, Gennaro Cataldo, Tommaso Addabbo, Cesare Biuzzi, Daniele Marianello, Carlo Alberto Volta, Fabio Silvio Taccone, Sabino Scolletta
Transpulmonary pressure (PL ) calculation requires esophageal pressure (PES ) as a surrogate of pleural pressure (Ppl), but its calibration is a cumbersome technique. Central venous pressure (CVP) swings may reflect tidal variations in Ppl and could be used instead of PES , but the interpretation of CVP waveforms could be difficult due to superposition of heartbeat-induced pressure changes. Thus, we developed a digital filter able to remove the cardiac noise to obtain a filtered CVP (f-CVP). The aim of the study was to evaluate the accuracy of CVP and filtered CVP swings (ΔCVP and Δf-CVP, respectively) in estimating esophageal respiratory swings (ΔPES ) and compare PL calculated with CVP, f-CVP and PES; then we tested the diagnostic accuracy of the f-CVP method to identify unsafe high PL levels, defined as PL >10 cmH2 O...
March 21, 2024: Journal of Clinical Monitoring and Computing
https://read.qxmd.com/read/38510907/effectiveness-of-ceftazidime-avibactam-in-gram-negative-nosocomial-pneumonia-a-real-world-study-in-india
#28
JOURNAL ARTICLE
Neha Gupta, Sanjith Saseedharan, Yashesh Paliwal
BACKGROUND AND OBJECTIVE: The incidences of nosocomial pneumonia in intensive care units (ICUs) in India have been reported to range from 9% to 58% and are associated with a mortality rate of 30-70%. Ceftazidime-avibactam has activity against OXA-48-like carbapenem-resistant Enterobacterales (CRE) and has a safer adverse effect profile as compared to the nephrotoxic colistin. The current study aimed to assess the effectiveness and usage pattern of ceftazidime-avibactam in gram-negative hospital-acquired pneumonia (HAP) and ventilator-associated pneumonia (VAP) in real-world settings in India...
February 2024: Curēus
https://read.qxmd.com/read/38510774/audit-on-practices-of-endotracheal-suctioning-in-intensive-care-unit-patients-among-health-care-workers-hcws
#29
JOURNAL ARTICLE
Rahil Singh, Anju Romina Bhalotra, Shubhangi Sharma
BACKGROUND: Endotracheal suctioning (ETS) is one of the most frequently performed invasive procedures in intensive care units (ICUs). This audit was aimed at studying current practices and knowledge regarding ETS in the Indian critical care setup, with the background aim of raising awareness regarding correct practices as per current recommendations in critically ill patients. MATERIALS AND METHODS: After registering the trial with the clinical trial registry, India, a structured audit questionnaire containing 20 questions pertaining to ETS was distributed through electronic media among resident doctors working in the ICUs across India...
January 2024: Indian Journal of Critical Care Medicine
https://read.qxmd.com/read/38508486/ex-vivo-lung-perfusion-in-donation-after-circulatory-death-a-post-hoc-analysis-of-the-novel-trial
#30
JOURNAL ARTICLE
Doug A Gouchoe, Pablo G Sanchez, Jonathan D'Cunha, Christian A Bermudez, Mani A Daneshmand, Robert D Davis, Matthew G Hartwig, Thomas C Wozniak, Zachary N Kon, Bartley P Griffith, William R Lynch, Tiago N Machuca, Michael J Weyant, Michael E Jessen, Michael S Mulligan, Frank D'Ovidio, Phillip C Camp, Edward Cantu, Bryan A Whitson
OBJECTIVE: Donation after circulatory death (DCD) donors offer the ability to expand the lung donor pool and ex vivo lung perfusion (EVLP) further contributes to this ability by allowing for additional evaluation and resuscitation of these extended criteria donors. We sought to determine the outcomes of recipients receiving organs from DCD EVLP donors in a multi-center setting. METHODS: This was an unplanned post-hoc analysis of a multicenter, prospective, non-randomized trial that took place in 2011-2017 with 3-years of follow up...
March 18, 2024: Journal of Thoracic and Cardiovascular Surgery
https://read.qxmd.com/read/38507221/progress-in-the-relationship-between-mechanical-ventilation-parameters-and-ventilator-related-complications-during-perioperative-anesthesia
#31
JOURNAL ARTICLE
Hu Yue, Tao Yong
BACKGROUND: Mechanical ventilation, as an important respiratory support, plays an important role in general anesthesia and it is the cornerstone of intraoperative management of surgical patients. Different from spontaneous respiration, intraoperative mechanical ventilation can lead to postoperative lung injury, and its impact on surgical mortality cannot be ignored. Postoperative lung injury increases hospital stay and is related to preoperative conditions, anesthesia time, and intraoperative ventilation settings...
March 20, 2024: Postgraduate Medical Journal
https://read.qxmd.com/read/38505316/aerosol-generating-procedures-and-associated-control-mitigation-measures-position-paper-from-the-canadian-dental-hygienists-association-and-the-american-dental-hygienists-association
#32
JOURNAL ARTICLE
Abdulrahman Ghoneim, Diego Proaño, Harpinder Kaur, Sonica Singhal
BACKGROUND: Since the outbreak of COVID-19, how to reduce the risk of spreading viruses and other microorganisms while performing aerosolgenerating procedures (AGPs) has become a challenging question within the dental and dental hygiene communities. The purpose of this position paper is to summarize the evidence of the effectiveness of various mitigation methods used to reduce the risk of infection transmission during AGPs in dentistry. METHODS: The authors searched 6 databases-MEDLINE, EMBASE, Scopus, Web of Science, Cochrane Library, and Google Scholar-for relevant scientific evidence published between January 2012 and December 2022 to answer 6 research questions about the risk of transmission, methods, devices, and personal protective equipment (PPE) used to reduce contact with microbial pathogens and limit the spread of aerosols...
February 2024: Canadian journal of dental hygiene: CJDH, Journal canadien de l'hygiène dentaire: JCHD
https://read.qxmd.com/read/38505007/analysis-of-the-hemostatic-effect-of-preset-wrapping-technique-for-type-a-aortic-dissection-with-abnormal-coagulation
#33
JOURNAL ARTICLE
Zhixiang Cai, Tao Yan, Ben Zhang, Weida Zhang, Chenjie Su, Hanwei Chen, Xianyue Wang
BACKGROUND: There are many techniques to reduce anastomotic bleeding for the total arch replacement, but hemostasis is sometimes difficult to achieve after surgery for acute dissection, especially in patients with abnormal coagulation (AC). This study aimed to investigate the hemostatic effect and early efficacy of a pre-set bovine pericardium wrapper in the right heart system shunt for total arch replacement in patients with type A aortic dissection (TAAD) and preoperative AC. METHODS: A retrospective analysis was conducted on 85 patients with TAAD and AC who underwent total arch replacement between January 2018 and December 2022...
February 29, 2024: Journal of Thoracic Disease
https://read.qxmd.com/read/38504443/ventilator-assisted-preoxygenation-in-an-aeromedical-retrieval-setting
#34
JOURNAL ARTICLE
Akmez Latona, Richard Pellatt, David Wedgwood, Gerben Keijzers, Steven Grant
OBJECTIVE: Ventilator-assisted preoxygenation (VAPOX) is a method of preoxygenation and apnoeic ventilation which has been tried in hospital setting. We aimed to describe VAPOX during intubation of critically unwell patients in aeromedical retrieval setting. METHODS: Retrospective observational study of VAPOX performed at LifeFlight Retrieval Medicine (LRM) between January 2018 and December 2022 across Queensland, Australia. Demographic and clinical data were recorded...
March 19, 2024: Emergency Medicine Australasia: EMA
https://read.qxmd.com/read/38504176/burden-and-risk-profile-of-acute-kidney-injury-in-severe-covid-19-pneumonia-admissions-a-finding-from-jimma-university-medical-center-ethiopia
#35
JOURNAL ARTICLE
Ebrahim Kelil Umer, Abel Tezera Abebe, Yabets Tesfaye Kebede, Nardos Tilahun Bekele
BACKGROUND: Acute kidney injury (AKI) is a serious complication of the Corona Virus Disease of 2019 (COVID-19). However, data on its magnitude and risk factors among hospitalized patients in Ethiopia is limited. This study aimed to determine the magnitude of AKI and associated factors among patients admitted for severe COVID-19 pneumonia. METHODS: An institution-based retrospective cross-sectional study was conducted among 224 patients admitted to Jimma University Medical Center in Ethiopia for severe COVID-19 pneumonia from May 2020 to December 2021...
March 20, 2024: BMC Nephrology
https://read.qxmd.com/read/38500035/availability-and-threshold-of-the-vasoactive-inotropic-score-for-predicting-early-extubation-in-adults-after-rheumatic-heart-valve-surgery-a-single-center-retrospective-cohort-study
#36
JOURNAL ARTICLE
Yang Zhao, Hanlei Zhao, Jiao Huang, Bo Mei, Jun Xiang, Yizheng Wang, Jingyan Lin, San Huang
BACKGROUND: Early extubation (EEx) is defined as the removal of the endotracheal tube within 8 h postoperatively. The present study involved determining the availability and threshold of the vasoactive-inotropic score (VIS) for predicting EEx in adults after elective rheumatic heart valve surgery. METHODS: The present study was designed as a single-center retrospective cohort study which was conducted with adults who underwent elective rheumatic heart valve surgery with CPB...
March 18, 2024: BMC Anesthesiology
https://read.qxmd.com/read/38497961/transition-to-weight-based-high-flow-nasal-cannula-use-outside-of-the-icu-for-bronchiolitis
#37
JOURNAL ARTICLE
Robert J Willer, Patrick W Brady, Amy N Tyler, Jennifer D Treasure, Eric R Coon
IMPORTANCE: Most children's hospitals have adopted weight-based high-flow nasal cannula (HFNC) bronchiolitis protocols for use outside of the intensive care unit (ICU) setting. Whether these protocols are achieving their goal of reducing bronchiolitis-related ICU admissions remains unknown. OBJECTIVE: To measure the association between hospital transition to weight-based non-ICU HFNC use and subsequent ICU admission. DESIGN, SETTING, AND PARTICIPANTS: This multicenter retrospective cohort study was conducted with a controlled interrupted time series approach and involved 18 children's hospitals that contribute data to the Pediatric Health Information Systems database...
March 4, 2024: JAMA Network Open
https://read.qxmd.com/read/38495300/the-influence-of-low-resistance-respiratory-muscle-training-on-pulmonary-function-and-high-intensity-exercise-performance
#38
JOURNAL ARTICLE
Hajed M Al-Otaibi, Francesco Sartor, Hans-Peter Kubis
BACKGROUND/OBJECTIVES: Respiratory muscle training (RMT) was recognized as an effective means to improve respiratory muscle (RM) strength and enhance exercise performance. The purpose of this study was to examine the effect of low-intensity RMT on RM strength, pulmonary function, and performance. METHODS: Fourteen healthy active adults were assigned randomly to either a training or placebo group. The training group completed six weeks of RMT, which consisted of a first week, 1 set of 15 min/d, 5 d/wk at 10-25% of maximal inspiratory pressure (PImax), and the remaining 5 weeks, 2 sets of 15 min/d, 5 d/wk, at 30% PImax...
July 2024: Journal of Exercise Science and Fitness
https://read.qxmd.com/read/38495224/integration-of-a-respiratory-function-monitor-into-newborn-positive-pressure-ventilation-training-development-of-a-standardised-training-intervention
#39
JOURNAL ARTICLE
C M Ni Chathasaigh, L Smiles, E O'Currain, A E Curley
OBJECTIVE: One in twenty newborns require resuscitation with positive pressure ventilation (PPV) at birth. Newborn face mask ventilation is often poorly performed. To address this, the potential role of respiratory function monitors (RFM) in newborn resuscitation training has been highlighted. The objective of this study was to develop a standardised training intervention on newborn PPV using an RFM with a simple visual display to identify and correct suboptimal ventilations. METHODS: We adapted the framework from a simulation development guideline to create a hands-on intervention on newborn PPV using an RFM with simple visual feedback (Monivent NeoTraining)...
June 2024: Resuscitation plus
https://read.qxmd.com/read/38495119/editorial-critical-care-applications-bridging-high-medium-and-low-income-settings
#40
EDITORIAL
Luigi Pisani, Wangari Waweru Siika, Madiha Hashmi
No abstract text is available yet for this article.
2024: Frontiers in Medicine
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