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Alveolar resorption

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https://www.readbyqxmd.com/read/28818443/types-of-external-root-resorption-of-replanted-teeth-analysis-of-the-clinical-aspects-and-of-interleukin-4-gene-polymorphisms-involvement
#1
Liliane Roskamp, Paula Cristina Trevilatto, Cleber Machado Souza, Ulisses Xavier Silva Neto, Everdan Carneiro, Luiz Fernando Fariniuk, Vânia Portela Ditzel Westphalen
INTRODUCTION: The absence or presence of root resorption on the surface of a replanted tooth indicates an immune-inflammatory reaction. Recent research even suggests the participation of host predominant immunologic profile on types of resorptions detected on the root surface. Because interleukin 4 (IL-4) is an important anti-inflammatory cytokine, this study aimed to investigate the association of clinical variables and polymorphisms in IL4 with types of resorption of replanted teeth after 1 year of follow-up...
August 14, 2017: Journal of Endodontics
https://www.readbyqxmd.com/read/28814141/effects-of-calcitonin-on-orthodontic-tooth-movement-and-associated-root-resorption-in-rats
#2
Ling Guan, Suai Lin, Weijun Yan, Lei Chen, Xiaofeng Wang
OBJECTIVES: Our main aim was to evaluate the effects of calcitonin (CT) on orthodontic tooth movement (OTM) and orthodontic root resorption in a rat model. MATERIAL AND METHODS: Eighty male Wistar rats were randomly divided into five groups. Rats in the negative control group were not given any appliances or injections. All the remaining rats were used to establish a model of OTM. The positive control group were then injected with normal saline, while rats in the three experimental groups were injected with 0...
August 17, 2017: Acta Odontologica Scandinavica
https://www.readbyqxmd.com/read/28762152/quantitative-analysis-of-the-relationship-between-maxillary-incisors-and-the-incisive-canal-by-cone-beam-computed-tomography-in-an-adult-japanese-population
#3
Tomonari Matsumura, Yuji Ishida, Ayako Kawabe, Takashi Ono
BACKGROUND: In setting goals for orthodontic treatment, determining the morphologies of the alveolar bone and maxillary incisor root is important for avoiding root resorption, dehiscence, and fenestration. This study aimed to analyze the configurational relationships among maxillary incisors, the alveolar border, and the incisive canal by cone-beam computed tomography (CBCT). METHODS: Cone-beam CT images of 93 orthodontic patients were evaluated for length of the incisive canal (L); angles between the palatal plane and the maxillary alveolar border (θ1), the incisive canal (θ2), and maxillary incisor (θ3); distance from the left maxillary incisor to the incisive canal (D); and cross-sectional areas of the incisive canal (CSAs) at three vertical levels...
December 2017: Progress in Orthodontics
https://www.readbyqxmd.com/read/28761940/management-of-ankylotic-root-resorption-following-dental-trauma-a-short-review-and-proposal-of-a-treatment-protocol
#4
Shaul Lin, Malka Ashkenazi, Munir Karawan, Sorin T Teich, Zvi Gutmacher
Ankylotic root resorption is a serious complication following traumatic dental injuries. The aetiology of root resorption includes acute injury to the cementum and periodontal ligament, and subsequent biological processes that propagate the harm. The aim of the present paper is to present a structured treatment protocol for teeth that have experienced trauma and are at risk of developing ankylotic root resorption, followed by a decoronation protocol for situations in which ankylotic root resorption developed...
July 31, 2017: Oral Health & Preventive Dentistry
https://www.readbyqxmd.com/read/28752939/effect-of-organic-silicon-methylsulfonylmethane-and-glucosamine-sulfate-in-mandibular-bone-defects-in-rats
#5
Flávia Santiago de Sousa Rosa, Rúbia Teodoro Stuepp, Filipe Modolo, Michelle Tillmann Biz
Organic silicon (OS), glucosamine sulfate (GS), and methylsulfonylmethane (MSM) have been related to bone and connective tissue health and have been considered as basic therapy for osteoarthrosis disorders. Therefore, the aim was to analyze the effect of the association of these three components in mandibular bone defects in rats. Nine rats were used for histocompatibility test. In each animal was implanted the composition (70% OS, 15% GS, 15% MSM) and gutta percha (control) under the dorsal subcutaneous tissue...
July 28, 2017: Microscopy Research and Technique
https://www.readbyqxmd.com/read/28745002/dimensional-changes-of-the-maxillary-sinus-following-tooth-extraction-in-the-posterior-maxilla-with-and-without-socket-preservation
#6
Itay Levi, Michal Halperin-Sternfeld, Jacob Horwitz, Hadar Zigdon-Giladi, Eli E Machtei
BACKGROUND: Sinus pneumatization is commonly observed following tooth extraction in the posterior maxilla, however, the role of this pneumatization in the overall changes in the vertical bone height is not clear. PURPOSE: To compare dimensional changes in the alveolar ridge and corresponding maxillary sinus following tooth extraction, with or without socket preservation. MATERIALS AND METHODS: 42 patients underwent tooth extraction (control group) and 21 patients underwent tooth extraction with socket preservation using DBBM (study group)...
July 26, 2017: Clinical Implant Dentistry and related Research
https://www.readbyqxmd.com/read/28738191/comparison-of-dental-implant-performance-following-vertical-alveolar-bone-augmentation-with-alveolar-distraction-osteogenesis-or-autogenous-onlay-bone-grafts-a-retrospective-cohort-study
#7
Kai Zhao, Feng Wang, Wei Huang, Yiqun Wu
PURPOSE: The aim of this retrospective study was to compare the performance of implants placed after alveolar distraction osteogenesis (ADO) or autogenous onlay bone grafting (AOBG) based on implant survival, peri-implant bone resorption, and clinical parameters. MATERIALS AND METHODS: From February 2008 to July 2012, 17 patients (6 women and 11 men) with implant placement after ADO (group 1, n = 8) or AOBG (group 2, n = 9) were included in this retrospective study...
July 1, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28736870/alveolar-bone-resorption-after-primary-tooth-loss-has-a-negative-impact-on-straightforward-implant-installation-in-patients-with-agenesis-of-the-lower-second-premolar
#8
Kristina Bertl, Michael H Bertl, Patrick Heimel, Maria Burt, André Gahleitner, Andreas Stavropoulos, Christian Ulm
OBJECTIVES: To compare the alveolar bone dimensions in patients with lower second premolar (P2) agenesis prior to and after primary molar loss on CT scans, and assess the possibility for straightforward implant placement. METHODS: Alveolar bone dimensions were evaluated on 150 mandibular CT scans in three groups: (i) agenesis of P2, with the primary tooth in situ, and regularly erupted first premolar (P1) and molar (M1) (AW); (ii) agenesis of P2, without the primary tooth in situ for ≥3 m, but regularly erupted P1 and M1 (AWO); and (iii) P1, P2, and M1 regularly erupted (CTR)...
July 23, 2017: Clinical Oral Implants Research
https://www.readbyqxmd.com/read/28736799/rankl-induced-osteoclastogenesis-is-suppressed-by-4-o-methylhonokiol-in-bone-marrow-derived-macrophages
#9
Kyung-Ran Park, Ji-Youn Kim, Eun-Cheol Kim, Hyung-Mun Yun, Jin Tae Hong
Magnolol, honokiol, and obovatol are well known bioactive constituents of the bark of Magnolia officinalis and have been reported to have beneficial effects in various diseases. We recently isolated a novel active compound, 4-O-methylhonokiol (4-O-MH) from the ethanol extract of M. officinalis, which was previously reported to have pharmacological effects including anti-inflammatory, anti-oxidative, and anti-aging activities. Here, we examined the pharmacological properties of 4-O-MH on osteoblast (bone-forming cells) and osteoclast (bone-resorbing cells) differentiation, and its underlying signaling pathways in primary cultured pre-osteoblasts and bone marrow macrophages...
July 24, 2017: Archives of Pharmacal Research
https://www.readbyqxmd.com/read/28735626/differentiation-of-hmsc-and-hpdlsc-induced-by-pge2-or-bmp-7-in-3d-models
#10
Christina Ern, Tamara Berger, Iris Frasheri, Richard Heym, Reinhard Hickel, Matthias Folwaczny
Regenerative therapies of pathogenic tissue defects are gaining increasing importance in periodontology. Among others, the osteogenic effect of BMP-7 seems to play a major role in the development of teeth and alveolar bone. Human periodontal ligament stem cells (hPDLSC), as well as human mesenchymal stem cells (hMSC), show the ability to differentiate into various types of tissues. Regarding prostaglandin E2, many studies have confirmed that it is involved in the inflammation associated to periodontitis stimulating osteoclasts, which ultimately leads to resorption of tooth supporting bone...
July 2017: Prostaglandins, Leukotrienes, and Essential Fatty Acids
https://www.readbyqxmd.com/read/28713971/systematic-analysis-of-lncrnas-mirnas-and-mrnas-for-the-identification-of-biomarkers-for-osteoporosis-in-the-mandible-of-ovariectomized-mice
#11
Lingyu Hao, Jiayao Fu, Yawen Tian, Junhua Wu
Osteoporosis is a complex and multifactorial disease caused by an imbalance between bone formation and resorption. Post‑menopausal women with endogenous estrogen deficiency suffer from systemic bone loss and osteoporosis, and are at high risk of this affecting the jaw bones. MicroRNAs (miRNAs or miRs) have been implicated in the mechanisms of metabolic bone diseases and are expressed at differential levels in alveolar bone following ovariectomy. In the present study, we systematically analyzed the expression profiles of miRNAs, mRNAs and long non‑coding RNA (lncRNAs) in the mandible of ovariectomized (OVX) mice...
September 2017: International Journal of Molecular Medicine
https://www.readbyqxmd.com/read/28698506/ubiquitination-in-periodontal-disease-a-review
#12
REVIEW
Sachio Tsuchida, Mamoru Satoh, Masaki Takiwaki, Fumio Nomura
Periodontal disease (periodontitis) is a chronic inflammatory condition initiated by microbial infection that leads to gingival tissue destruction and alveolar bone resorption. The periodontal tissue's response to dental plaque is characterized by the accumulation of polymorphonuclear leukocytes, macrophages, and lymphocytes, all of which release inflammatory mediators and cytokines to orchestrate the immunopathogenesis of periodontal disease. Ubiquitination is achieved by a mechanism that involves a number of factors, including an ubiquitin-activating enzyme, ubiquitin-conjugating enzyme, and ubiquitin-protein ligase...
July 10, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28689017/parathyroid-hormone-related-peptide-1-34-reduces-alveolar-bone-loss-in-type-1-diabetic-rats
#13
Wen Zhang, Su-Zhen Wu, Jian Zhou, Hong-Min Chen, Ye-Li Gong, Fang-Fang Peng, Bai-Fang Zhang
OBJECTIVE: To investigate the role of parathyroid hormone related protein (PTHrP) in diabetic periodontitis. METHODS: After injected with 55mg/kg streptozotocin, diabetic rats were treated subcutaneously with low-dose (40μg/kg, once daily for 5days per week), middle-dose (80μg/kg) or high-dose (160μg/kg) PTHrP(1-34) peptide. Treatment continued for 12 weeks. Changes in periodontal tissues were confirmed by micro-computerized tomography assay and H&E analysis...
June 24, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/28677938/alveolar-splitting-with-piezosurgery-bone-bank-grafts-and-nobelactive-implants-as-an-alternative-to-major-bone-grafting-for-maxillary-reconstruction
#14
Massimo Albanese, Giulia Ricciardi, Dario Donadello, Alessandra Lucchese, Federico Gelpi, Alessandro Zangani, Daniele DE Santis, Alessandro Rizzini, Alberto Rossetto, Dario Bertossi
BACKGROUND: Piezo-surgery represents a novel alternative technique. The Piezo-surgery is well tolerated and permits a large number of applications in decribed literature. The principle of piezo-surgery consists into inducing micro-vibrations to a metallic insert with a particular custom. The aim of this article is to study and to evaluate the use of Nobelactive implants in combination with piezosurgical split-crest technique in severe atrophy of the upper maxilla. This approach allows avoiding the use of onlay grafts, due to rise the trasversal width of the crestal bone, which could have more complications and uncertain prognosis...
July 4, 2017: Minerva Stomatologica
https://www.readbyqxmd.com/read/28674791/effects-of-the-gaalas-diode-laser-780%C3%A2-nm-on-the-periodontal-tissues-during-orthodontic-tooth-movement-in-diabetes-rats-histomorphological-and-immunohistochemical-analysis
#15
Mônica Fernandes Gomes, Maria da Graças Vilela Goulart, Lilian Chrystiane Giannasi, Cybelle Mori Hiraoka, Gabriela de Fátima Santana Melo, Aretha Graziela Vilela de Sousa, Celestino José Prudente Nóbrega, Renato Amaro Zangaro, Miguel Angel Castillo Salgado
The purposes of the present study are to assess the effects of the GaAlAs diode laser on the periodontal tissues and to investigate its action on the alveolar bone remodeling process during orthodontic tooth movement in normoglycemic and diabetic rats. Sixty adult male Wistar rats were divided into four groups of 15 rats: normoglycemic (N), diabetic (D), laser-normoglycemic (LN), and laser-diabetic (LD) rats. Diabetes mellitus was induced by a single intravenous injection of 40 mg/kg monohydrated alloxan. The orthodontically moved tooth underwent a force magnitude of 20 cN...
July 3, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28662142/effects-of-the-probiotic-bifidobacterium-animalis-subsp-lactis-on-the-non-surgical-treatment-of-periodontitis-a-histomorphometric-microtomographic-and-immunohistochemical-study-in-rats
#16
Milla S T Ricoldi, Flávia A C Furlaneto, Luiz F F Oliveira, Gustavo C Teixeira, Jéssica P Pischiotini, André L G Moreira, Edilson Ervolino, Maricê N de Oliveira, Cristina S B Bogsan, Sérgio L Salvador, Michel R Messora
Lactobacillus probiotics have been investigated in periodontitis. However, the effects of the genus Bifidobacterium on periodontitis are hardly known. This study evaluated the effects of the probiotic (PROB) Bifidobacterium animalis subsp. lactis (B. lactis) HN019 as an adjunct to scaling and root planing (SRP) in rats with experimental periodontitis (EP). At baseline, 32 rats were assigned to 4 groups: C (control), PROB, EP-SRP and EP-SRP-PROB. In groups EP-SRP and EP-SRP-PROB, the mandibular first molars of the animals received a ligature...
2017: PloS One
https://www.readbyqxmd.com/read/28650786/alveolar-fracture-caused-by-tooth-extraction-at-home
#17
Fabrício Kitazono de Carvalho, Thaís Aparecida Xavier, Nicole Gonçalves Lima, Alexandra Mussolino de Queiroz, Marcilene Coelho Vinhorte, Paulo Nelson-Filho
Injuries to the teeth and surrounding structures are relatively common. Although traumatic injuries caused by falls or activities related to sports are widely discussed, the same cannot be said regarding accidents arising from non-professional extraction of primary teeth. The present study reports a 6-year-old male child who underwent mandibular alveolar bone fracture during non-professional extraction of his central lower left incisor at home, performed by his 30-year-old aunt. The root of the tooth was with an irregular physiological resorption, which acted as a lever component for the mechanical force applied, leading to bone fracture...
2017: Journal of Clinical Pediatric Dentistry
https://www.readbyqxmd.com/read/28647647/itraq-based-quantitative-analysis-of-alveolar-bone-resorption-in-rats-with-experimental-periodontitis
#18
Weidong Yang, Yafan Gao, Yajie Qian, Jingjing Li, Qingang Hu
OBJECTIVE: Periapical periodontitis results in alveolar bone resorption around the root apex. During the progression of inflammation, host cells release various inflammatory mediators and pro-inflammatory cytokines through immune responses. However, the pathological mechanisms associated with periapical bone destruction remain unclear. This study was objected to identify differentially regulated proteins in periapical periodontitis via a quantitative proteomics approach using isobaric tags for relative and absolute quantification (iTRAQ) labelling of peptides...
June 13, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/28643923/micro-anatomical-responses-in-periodontal-complexes-of-mice-to-calibrated-orthodontic-forces-on-the-crown
#19
A Pal, L Chen, L Yang, F Yang, B Meng, A H Jheon, S P Ho
OBJECTIVE: Correlating mechanical forces with quantifiable physical changes in the dentoalveolar complex. SETTING AND SAMPLE POPULATION: Male 6-week C57BL/6 mice (N=3), micro X-ray-computed tomography; post-analysis software to extract physical changes in periodontal ligament (PDL)-space. MATERIALS AND METHODS: Silicone-elastic bands were placed between maxillary molars for 1 week, with the contralateral side as internal control. Average displacements between crowns and roots, and changes in PDL-spaces were evaluated by registering X-ray tomograms of experimental and control hemi-maxillae...
June 2017: Orthodontics & Craniofacial Research
https://www.readbyqxmd.com/read/28634845/histomorphometric-and-immunohistochemical-evaluation-of-collagen-containing-xenogeneic-bone-blocks-used-for-lateral-bone-augmentation-in-staged-implant-placement
#20
Alberto Ortiz-Vigón, Sergio Martinez-Villa, Iñaki Suarez, Fabio Vignoletti, Mariano Sanz
BACKGROUND: The osteoconductive properties of collagen containing xenogeneic bone blocks (CCXBB) remain unclear. The aim of this prospective single-arm clinical study was to assess the histological outcomes of CCXBB blocks used as bone replacement grafts for lateral bone augmentation procedures. METHODS: In 15 patients with severe horizontal alveolar ridge resorption, lateral augmentation procedures were performed using CCXBB as bone replacement grafts. Twenty-six weeks postoperatively, a re-entry procedure was performed to evaluate the bone width for adequate implant placement and two histological specimens were retrieved from each patient, one being processed for ground sectioning and the other for decalcified paraffin-included sections...
December 2017: International Journal of Implant Dentistry
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