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Alveolar resorption

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https://www.readbyqxmd.com/read/28098768/preventive-effects-of-drinking-hydrogen-rich-water-on-gingival-oxidative-stress-and-alveolar-bone-resorption-in-rats-fed-a-high-fat-diet
#1
Toshiki Yoneda, Takaaki Tomofuji, Muneyoshi Kunitomo, Daisuke Ekuni, Koichiro Irie, Tetsuji Azuma, Tatsuya Machida, Hisataka Miyai, Kouhei Fujimori, Manabu Morita
Obesity induces gingival oxidative stress, which is involved in the progression of alveolar bone resorption. The antioxidant effect of hydrogen-rich water may attenuate gingival oxidative stress and prevent alveolar bone resorption in cases of obesity. We examined whether hydrogen-rich water could suppress gingival oxidative stress and alveolar bone resorption in obese rats fed a high-fat diet. Male Fischer 344 rats (n = 18) were divided into three groups of six rats each: a control group (fed a regular diet and drinking distilled water) and two experimental groups (fed a high-fat diet and drinking distilled water or hydrogen-rich water)...
January 13, 2017: Nutrients
https://www.readbyqxmd.com/read/28093319/anti-inflammatory-effect-of-the-salvia-sclarea-l-ethanolic-extract-on-lipopolysaccharide-induced-periodontitis-in-rats
#2
Milica Kostić, Dušanka Kitić, Milica B Petrović, Tatjana Jevtović-Stojmenov, Marko Jović, Aleksandar Petrović, Slavoljub Živanović
ETHNOPHARMACOLOGICAL RELEVANCE: Salvia sclarea L., clary, is an aromatic plant traditionally used in folk medicine for the treatment of various diseases and conditions. Although it has been primarily used as a stomachic, there are data on traditional use of S. sclarea as an agent against gingivitis, stomatitis and aphthae. AIM OF THE STUDY: The aim of the study was to examine the effect of the S. sclarea ethanolic extract on the lipopolysaccharide (LPS)-induced periodontitis in rats from the immunological and histopathological standpoint...
January 13, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28081379/direct-gingival-fibroblast-osteoblast-transdifferentiation-via-epigenetics
#3
Y Cho, B Kim, H Bae, W Kim, J Baek, K Woo, G Lee, Y Seol, Y Lee, Y Ku, I Rhyu, H Ryoo
Alveolar bone resorption caused by trauma or periodontal diseases has represented a challenge for both dental clinicians and researchers. In this study, we evaluate the osteogenic potential of human gingival fibroblasts (HGFs) through a direct transdifferentiation from HGFs to functional osteoblasts via epigenetic modification and osteogenic signaling with bone morphogenetic protein 2 (BMP2) in vitro and in vivo. HGF treatment with 5-aza-2'-deoxycytidine (5-aza-dC) induced demethylation in the hypermethylated CpG islands of the osteogenic lineage marker genes RUNX2 and ALP, and subsequent BMP2 treatment successfully drove the fibroblasts to the osteoblasts' lineage...
January 1, 2017: Journal of Dental Research
https://www.readbyqxmd.com/read/28081372/role-of-hyperplasia-of-gingival-lymphatics-in-periodontal-inflammation
#4
P Papadakou, A Bletsa, M A Yassin, T V Karlsen, H Wiig, E Berggreen
Lymphatic vessels are important for maintenance of tissue fluid homeostasis and afferent antigen transport. In chronic inflammation, lymphangiogenesis takes place and is characterized by lymphatic endothelial cell proliferation and lymphatic hyperplasia. Vascular endothelial growth factor C (VEGFC) is the main known lymphangiogenic growth factor, and its expression is increased in periodontitis, a common chronic infectious disease that results in tissue destruction and alveolar bone loss. The role of lymphangiogenesis during development of periodontitis is unknown...
December 1, 2016: Journal of Dental Research
https://www.readbyqxmd.com/read/28042439/full-arch-rehabilitation-in-severe-maxillary-atrophy-with-palatal-approach-implant-placement-a-case-report
#5
M Andreasi Bassi, M A Lopez, C Andrisani, Z Ormanier, M Gargari
PURPOSE: The edentulous severely atrophic maxilla, as consequence of alveolar bone resorption and pneumatisation of the maxillary sinus, represents a serious limitation to the implant rehabilitation. Implants insertion via palatal approach (PA), in combination with relatively minimally invasive techniques aimed at increasing bone volume without the use of autologous bone harvesting is a valid alternative among the options for the rehabilitation of the upper jaw. CLINICAL CASE: In a 70-year-old female, with a severe maxillary atrophy, 6 spiral taper implants were placed with the PA, combined with the bilateral transcrestal elevation of both the sinus floors and nasal cavities; a further GBR, with resorbable pericardium membrane covering a termoplastic allograft associated to a xenograft, was performed...
July 2016: Oral & Implantology
https://www.readbyqxmd.com/read/28033193/effect-of-platelet-rich-plasma-on-bone-grafting-of-alveolar-clefts
#6
Reiko Sakio, Yoshiaki Sakamoto, Hisao Ogata, Teruo Sakamoto, Takenobu Ishii, Kazuo Kishi
The purpose of this study was to evaluate the effectiveness of platelet-rich plasma (PRP) on the absorption of the bone graft in the alveolar cleft.Twenty-nine patients with alveolar clefts in unilateral cleft lip were examined; 6 were the control group and received iliac cancellous bone and marrow grafts without PRP, while the remaining 23 comprised the PRP group and received grafts with PRP. Quantitative evaluation of remaining bone was made by the computer-aided engineering with multidetector row computed tomography at 1 month and 1 year after surgery...
December 28, 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28029186/adipokine-chemerin-bridges-metabolic-dyslipidemia-and-alveolar-bone-loss-in-mice
#7
Erivan S Ramos-Junior, Gisele A Leite, Cecilia C Carmo-Silva, Thaise M Taira, Karla B Neves, David F Colón, Lea Ab da Silva, Sergio L Salvador, Rita C Tostes, Fernando Q Cunha, Sandra Y Fukada
Chemerin is an adipokine that regulates adipogenesis and metabolic functions of mature adipocytes mainly through the activation of chemokine-like receptor 1 (CMKLR1). Elevated levels of chemerin have been found in individuals with obesity, type-2 diabetes, and osteoporosis. This adipokine was identified as an inflammatory and metabolic syndrome marker. Considering that the association between metabolic syndrome and bone health remains unclear, the present study aimed to clarify the role of chemerin in the pathophysiology of bone loss induced by dyslipidemia, particularly modulating osteoclastogenesis...
December 28, 2016: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/28005801/zygomatic-implant-subjected-to-immediate-loading-for-atrophic-maxilla-rehabilitation
#8
Pâmela Letícia Dos Santos, Gustavo Henrique Souza Silva, Fernanda Rayssa Da Silva Pereira, Raquel Damazia da Silva, Mirella Lindoso Gomes Campos, Thiago Borges Mattos, Jéssica Lemos Gulinelli
As life expectancy increases, a larger number of elderly people require dental health care attention for implant-supported rehabilitation, with the aim of restoring the function and aesthetics of the oral cavity. Most of these patients have lost their teeth long time ago, causing a severe bone resorption and maxillary sinus pneumatization. Therefore, the current study aims to demonstrate, through the description of the clinical case, the treatment with zygomatic implants as an option for treating severely atrophic maxillas...
November 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/27999789/marginal-bone-level-evaluation-after-functional-loading-around-two-different-dental-implant-designs
#9
Ko-Ning Ho, Eisner Salamanca, Hsi-Kuai Lin, Sheng-Yang Lee, Wei-Jen Chang
Purpose. To investigate peri-implant alveolar bone changes using periapical radiographs before and after prosthetic delivery in submerged and nonsubmerged dental implants. Methods. Digital periapical films of 60 ITI Straumann nonsubmerged dental implants and 60 Xive Dentsply submerged dental implants were taken before, immediately after, and 12 and 24 weeks after the prosthetic restoration was delivered. Results. The 60-nonsubmerged dental implant group showed mean marginal bone resorption at baseline of 0...
2016: BioMed Research International
https://www.readbyqxmd.com/read/27992569/interleukin-33-and-rank-l-interplay-in-the-alveolar-bone-loss-associated-to-periodontitis
#10
Olivier Lapérine, Alexandra Cloitre, Jocelyne Caillon, Olivier Huck, Isaac Maximiliano Bugueno, Paul Pilet, Sophie Sourice, Elodie Le Tilly, Gaby Palmer, Jean-Luc Davideau, Valérie Geoffroy, Jérôme Guicheux, Sarah Beck-Cormier, Philippe Lesclous
INTRODUCTION: Chronic Periodontitis (CP) is an inflammatory disease of bacterial origin that results in alveolar bone destruction. Porphyromonas gingivalis (Pg), one of the main periopathogens, initiates an inflammatory cascade by host immune cells thereby increasing recruitment and activity of osteoclasts, the bone resorbing cells, through enhanced production of the crucial osteoclastogenic factor, RANK-L. Antibodies directed against some cytokines (IL-1β, IL-6 and TNF-α) failed to exhibit convincing therapeutic effect in CP...
2016: PloS One
https://www.readbyqxmd.com/read/27976596/influence-of-non-impacted-third-molars-on-the-pathologies-of-adjacent-second-molars-a-retrospective-study
#11
Zhi-Bang Li, Hong-Lei Qu, Li-Na Zhou, Bei-Min Tian, Fa-Ming Chen
BACKGROUND: Although the removal of impacted third molars (I-M3s) is common in dental clinics, the decision to retain or remove asymptomatic non-impacted third molars (N-M3s) presents a significant challenge. This study investigated the influence of N-M3s on the pathologies of the adjacent second molars (A-M2s). METHODS: The clinical status of M3s was evaluated, and the presence of distal caries, the external root resorption (ERR) and the alveolar bone loss of A-M2s were assessed by orthopantomograms (OPGs)...
December 15, 2016: Journal of Periodontology
https://www.readbyqxmd.com/read/27940164/rankl-release-from-self-assembling-nanofiber-hydrogels-for-inducing-osteoclastogenesis-in-vitro
#12
James Z Xing, Lei Lu, Larry D Unsworth, Paul W Major, Michael R Doschak, Neelambar R Kaipatur
PURPOSE: To develop a nanofiber hydrogel (NF-hydrogel) for sustained and controlled release of the recombinant receptor activator of NF-kB ligand; (RANKL) and to characterize the release kinetics and bioactivity of the released RANKL. METHODS: Various concentrations of fluorescently-labelled RANKL protein were added to NF-hydrogels, composed of Acetyl-(Arg-Ala-Asp-Ala)4-CONH2 [(RADA)4] of different concentrations, to investigate the resulting in vitro release rates...
December 7, 2016: Acta Biomaterialia
https://www.readbyqxmd.com/read/27936914/characteristic-features-of-odontogenic-myxoma-on-cone-beam-computed-tomography
#13
Kaili Wang, Wenhao Guo, Meng You, Li Liu, Bei Tang, Guangning Zheng
OBJECTIVES: To illustrate characteristic features of odontogenic myxoma (OM) on CBCT. METHODS: From fifty-two subjects with histopathologically diagnosed odontogenic myxomas, eighteen that underwent CBCT examination were retrieved between May 2009 and April 2016. Features on CBCT images and clinical records were carefully observed and analyzed. RESULTS: Characteristic features include: (1) Fine and straight septa were recognized to separate the tumor into triangular, square or rectangular spaces which appeared as "tennis racket" or "honeycomb" patterns; (2) Septa frequently scattered to the borders of lesions and appeared perpendicular to the margins; (3) Tooth displacement and resorption were seen in most of OM lesions; (4) OMs were noted to have a tendency to involve the alveolar process, scalloped between the roots, and affected the integrity of the alveolar ridge; (5) The cortex of OMs appeared normally perforated and the edge of the cortex expanded into the soft tissue...
December 12, 2016: Dento Maxillo Facial Radiology
https://www.readbyqxmd.com/read/27933212/spontaneous-destructive-periodontitis-and-skeletal-bone-damage-in-transgenic-mice-carrying-a-human-shared-epitope-coding-hla-drb1-allele
#14
Prashasnika Gehlot, Sarah L Volk, Hector F Rios, Karl J Jepsen, Joseph Holoshitz
OBJECTIVE: Shared epitope (SE)-coding DRB1 alleles are associated with bone erosion in several diseases, including rheumatoid arthritis (RA) and periodontal disease (PD), but the underlying mechanism is unknown. We have recently identified the SE as an osteoclast-activating ligand. To better understand the biological effects of the SE in vivo, here we sought to determine whether it can facilitate spontaneous bone damage in naïve mice. METHODS: 3-month old naïve transgenic mice that carry the human SE-coding allele DRB1*04:01, or a SE-negative allele DRB1*04:02 were studied...
2016: RMD Open
https://www.readbyqxmd.com/read/27896212/effect-of-slow-forced-eruption-on-the-vertical-levels-of-the-interproximal-bone-and-papilla-and-the-width-of-the-alveolar-ridge
#15
Eun-Young Kwon, Ju-Youn Lee, Jeomil Choi
OBJECTIVE: Forced eruption has been proposed for the reconstruction of deficient bone and soft tissue. The aim of this study was to examine the changes in the alveolar ridge width and the vertical levels of the interproximal bone and papilla following forced eruption. METHODS: Patients whose hopeless maxillary anterior teeth were expected to undergo severe bone resorption and soft tissue recession upon extraction were recruited. In addition, patients whose maxillary anterior teeth required forced eruption for restoration due to tooth fracture or dental caries were included...
November 2016: Korean Journal of Orthodontics
https://www.readbyqxmd.com/read/27891638/regenerative-potential-of-leucocyte-and-platelet-rich-fibrin-l-prf-part-b-sinus-floor-elevation-alveolar-ridge-preservation-and-implant-therapy-a-systematic-review
#16
REVIEW
Ana B Castro, Nastaran Meschi, Andy Temmerman, Nelson Pinto, Paul Lambrechts, Wim Teughels, Marc Quirynen
AIM: To analyse the effect of Leucocyte- and Platelet Rich Fibrin (L-PRF) on bone regeneration procedures and osseointegration. MATERIALS AND METHODS: An electronic and hand search was conducted in three databases (MEDLINE, EMBASE and Cochrane). Only randomised clinical trials, written in English where L-PRF was applied in bone regeneration and implant procedures, were selected. No follow-up restrictions were applied. RESULTS: A total of 14 articles were included and processed...
November 28, 2016: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/27882310/minimal-invasive-horizontal-ridge-augmentation-using-subperiosteal-tunneling-technique
#17
Hyun-Suk Kim, Young-Kyun Kim, Pil-Young Yun
BACKGROUND: The goal of this study was to retrospectively evaluate the prognosis of minimal invasive horizontal ridge augmentation (MIHRA) technique using small incision and subperiosteal tunneling technique. METHODS: This study targeted 25 partially edentulous patients (10 males and 15 females, mean age 48.8 ± 19.7 years) who needed bone graft for installation of the implants due to alveolar bone deficiency. The patients took the radiographic exam, panoramic and periapical view at first visit, and had implant fixture installation surgery...
December 2016: Maxillofacial Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/27881312/detachable-cheek-plumpers-with-different-attachments-for-improving-esthetics-in-a-conventional-complete-denture-a-clinical-report
#18
Nikita M Virdiya, Jayant N Palaskar, Jyoti Wankhade, Nikhil Joshi
Aging is associated with loss of teeth, resorption of the alveolar process, and reduced tonicity of the facial muscles, leading to sunken cheeks and an unesthetic appearance. Esthetics in patients in need of complete dentures can be improved with the help of cheek plumpers to support the cheeks. They are noninvasive and straightforward to fabricate. Despite the reported success with the sole use of maxillary cheek plumpers, in certain situations, maxillary cheek plumpers provide inadequate support to the cheeks, evident in the lower third of the face...
October 27, 2016: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/27878769/to-what-extent-residual-alveolar-ridge-can-be-preserved-by-implant-a-systematic-review
#19
REVIEW
Ahmed Khalifa Khalifa, Masahiro Wada, Kazunori Ikebe, Yoshinobu Maeda
BACKGROUND: It has been reported that the load for (or to) implant-supported restoration may lead to bone remodeling as bone resorption and/or formation. While many authors supported the process of bone resorption, others elaborated bone apposition and increasing bone density close and remote to implant body (or fixture). This may suggest the role of the implant to reserve alveolar ridge from physiologic/pathologic resorption. The aim of this systematic review was to predict to how extend dental implants can preserve the residual alveolar ridge based on previous clinical investigations...
December 2016: International Journal of Implant Dentistry
https://www.readbyqxmd.com/read/27876715/-diagnostics-of-tooth-supporting-structures
#20
K A Morozov, A P Matveev, E K Morozov, Yu V Kabanov
The aim of the study was to assess alveolar bone resorption in patients with periodontal disease and individuals with normal periodontal status and coordinate resorbtion rates with tooth mobility. Tooth mobility was measured in 19 patients with periodontal disease and 17 healthy individuals by two-parametrical periodontometry in two different positions: in equilibrium and after pre-loading. The level of bone resorption was determined by periodontal probe. Previously unknown correlation between tooth mobility and alveolar bone resorption was found out meaning that bone atrophy can be determined by tooth mobility...
2016: Stomatologii︠a︡
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