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Alveolar resorption

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https://www.readbyqxmd.com/read/28713971/systematic-analysis-of-lncrnas-mirnas-and-mrnas-for-the-identification-of-biomarkers-for-osteoporosis-in-the-mandible-of-ovariectomized-mice
#1
Lingyu Hao, Jiayao Fu, Yawen Tian, Junhua Wu
Osteoporosis is a complex and multifactorial disease caused by an imbalance between bone formation and resorption. Post‑menopausal women with endogenous estrogen deficiency suffer from systemic bone loss and osteoporosis, and are at high risk of this affecting the jaw bones. MicroRNAs (miRNAs or miRs) have been implicated in the mechanisms of metabolic bone diseases and are expressed at differential levels in alveolar bone following ovariectomy. In the present study, we systematically analyzed the expression profiles of miRNAs, mRNAs and long non‑coding RNA (lncRNAs) in the mandible of ovariectomized (OVX) mice...
July 10, 2017: International Journal of Molecular Medicine
https://www.readbyqxmd.com/read/28698506/ubiquitination-in-periodontal-disease-a-review
#2
REVIEW
Sachio Tsuchida, Mamoru Satoh, Masaki Takiwaki, Fumio Nomura
Periodontal disease (periodontitis) is a chronic inflammatory condition initiated by microbial infection that leads to gingival tissue destruction and alveolar bone resorption. The periodontal tissue's response to dental plaque is characterized by the accumulation of polymorphonuclear leukocytes, macrophages, and lymphocytes, all of which release inflammatory mediators and cytokines to orchestrate the immunopathogenesis of periodontal disease. Ubiquitination is achieved by a mechanism that involves a number of factors, including an ubiquitin-activating enzyme, ubiquitin-conjugating enzyme, and ubiquitin-protein ligase...
July 10, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28689017/parathyroid-hormone-related-peptide-1-34-reduces-alveolar-bone-loss-in-type-1-diabetic-rats
#3
Wen Zhang, Su-Zhen Wu, Jian Zhou, Hong-Min Chen, Ye-Li Gong, Fang-Fang Peng, Bai-Fang Zhang
OBJECTIVE: To investigate the role of parathyroid hormone related protein (PTHrP) in diabetic periodontitis. METHODS: After injected with 55mg/kg streptozotocin, diabetic rats were treated subcutaneously with low-dose (40μg/kg, once daily for 5days per week), middle-dose (80μg/kg) or high-dose (160μg/kg) PTHrP(1-34) peptide. Treatment continued for 12 weeks. Changes in periodontal tissues were confirmed by micro-computerized tomography assay and H&E analysis...
June 24, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/28677938/alveolar-splitting-with-piezosurgery-bone-bank-grafts-and-nobelactive-implants-as-an-alternative-to-major-bone-grafting-for-maxillary-reconstruction
#4
Massimo Albanese, Giulia Ricciardi, Dario Donadello, Alessandra Lucchese, Federico Gelpi, Alessandro Zangani, Daniele DE Santis, Alessandro Rizzini, Alberto Rossetto, Dario Bertossi
BACKGROUND: Piezo-surgery represents a novel alternative technique. The Piezo-surgery is well tolerated and permits a large number of applications in decribed literature. The principle of piezo-surgery consists into inducing micro-vibrations to a metallic insert with a particular custom. The aim of this article is to study and to evaluate the use of Nobelactive implants in combination with piezosurgical split-crest technique in severe atrophy of the upper maxilla. This approach allows avoiding the use of onlay grafts, due to rise the trasversal width of the crestal bone, which could have more complications and uncertain prognosis...
July 4, 2017: Minerva Stomatologica
https://www.readbyqxmd.com/read/28674791/effects-of-the-gaalas-diode-laser-780%C3%A2-nm-on-the-periodontal-tissues-during-orthodontic-tooth-movement-in-diabetes-rats-histomorphological-and-immunohistochemical-analysis
#5
Mônica Fernandes Gomes, Maria da Graças Vilela Goulart, Lilian Chrystiane Giannasi, Cybelle Mori Hiraoka, Gabriela de Fátima Santana Melo, Aretha Graziela Vilela de Sousa, Celestino José Prudente Nóbrega, Renato Amaro Zangaro, Miguel Angel Castillo Salgado
The purposes of the present study are to assess the effects of the GaAlAs diode laser on the periodontal tissues and to investigate its action on the alveolar bone remodeling process during orthodontic tooth movement in normoglycemic and diabetic rats. Sixty adult male Wistar rats were divided into four groups of 15 rats: normoglycemic (N), diabetic (D), laser-normoglycemic (LN), and laser-diabetic (LD) rats. Diabetes mellitus was induced by a single intravenous injection of 40 mg/kg monohydrated alloxan. The orthodontically moved tooth underwent a force magnitude of 20 cN...
July 3, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28662142/effects-of-the-probiotic-bifidobacterium-animalis-subsp-lactis-on-the-non-surgical-treatment-of-periodontitis-a-histomorphometric-microtomographic-and-immunohistochemical-study-in-rats
#6
Milla S T Ricoldi, Flávia A C Furlaneto, Luiz F F Oliveira, Gustavo C Teixeira, Jéssica P Pischiotini, André L G Moreira, Edilson Ervolino, Maricê N de Oliveira, Cristina S B Bogsan, Sérgio L Salvador, Michel R Messora
Lactobacillus probiotics have been investigated in periodontitis. However, the effects of the genus Bifidobacterium on periodontitis are hardly known. This study evaluated the effects of the probiotic (PROB) Bifidobacterium animalis subsp. lactis (B. lactis) HN019 as an adjunct to scaling and root planing (SRP) in rats with experimental periodontitis (EP). At baseline, 32 rats were assigned to 4 groups: C (control), PROB, EP-SRP and EP-SRP-PROB. In groups EP-SRP and EP-SRP-PROB, the mandibular first molars of the animals received a ligature...
2017: PloS One
https://www.readbyqxmd.com/read/28650786/alveolar-fracture-caused-by-tooth-extraction-at-home
#7
Fabrício Kitazono de Carvalho, Thaís Aparecida Xavier, Nicole Gonçalves Lima, Alexandra Mussolino de Queiroz, Marcilene Coelho Vinhorte, Paulo Nelson-Filho
Injuries to the teeth and surrounding structures are relatively common. Although traumatic injuries caused by falls or activities related to sports are widely discussed, the same cannot be said regarding accidents arising from non-professional extraction of primary teeth. The present study reports a 6-year-old male child who underwent mandibular alveolar bone fracture during non-professional extraction of his central lower left incisor at home, performed by his 30-year-old aunt. The root of the tooth was with an irregular physiological resorption, which acted as a lever component for the mechanical force applied, leading to bone fracture...
2017: Journal of Clinical Pediatric Dentistry
https://www.readbyqxmd.com/read/28647647/itraq-based-quantitative-analysis-of-alveolar-bone-resorption-in-rats-with-experimental-periodontitis
#8
Weidong Yang, Yafan Gao, Yajie Qian, Jingjing Li, Qingang Hu
OBJECTIVE: Periapical periodontitis results in alveolar bone resorption around the root apex. During the progression of inflammation, host cells release various inflammatory mediators and pro-inflammatory cytokines through immune responses. However, the pathological mechanisms associated with periapical bone destruction remain unclear. This study was objected to identify differentially regulated proteins in periapical periodontitis via a quantitative proteomics approach using isobaric tags for relative and absolute quantification (iTRAQ) labelling of peptides...
June 13, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/28643923/micro-anatomical-responses-in-periodontal-complexes-of-mice-to-calibrated-orthodontic-forces-on-the-crown
#9
A Pal, L Chen, L Yang, F Yang, B Meng, A H Jheon, S P Ho
OBJECTIVE: Correlating mechanical forces with quantifiable physical changes in the dentoalveolar complex. SETTING AND SAMPLE POPULATION: Male 6-week C57BL/6 mice (N=3), micro X-ray-computed tomography; post-analysis software to extract physical changes in periodontal ligament (PDL)-space. MATERIALS AND METHODS: Silicone-elastic bands were placed between maxillary molars for 1 week, with the contralateral side as internal control. Average displacements between crowns and roots, and changes in PDL-spaces were evaluated by registering X-ray tomograms of experimental and control hemi-maxillae...
June 2017: Orthodontics & Craniofacial Research
https://www.readbyqxmd.com/read/28634845/histomorphometric-and-immunohistochemical-evaluation-of-collagen-containing-xenogeneic-bone-blocks-used-for-lateral-bone-augmentation-in-staged-implant-placement
#10
Alberto Ortiz-Vigón, Sergio Martinez-Villa, Iñaki Suarez, Fabio Vignoletti, Mariano Sanz
BACKGROUND: The osteoconductive properties of collagen containing xenogeneic bone blocks (CCXBB) remain unclear. The aim of this prospective single-arm clinical study was to assess the histological outcomes of CCXBB blocks used as bone replacement grafts for lateral bone augmentation procedures. METHODS: In 15 patients with severe horizontal alveolar ridge resorption, lateral augmentation procedures were performed using CCXBB as bone replacement grafts. Twenty-six weeks postoperatively, a re-entry procedure was performed to evaluate the bone width for adequate implant placement and two histological specimens were retrieved from each patient, one being processed for ground sectioning and the other for decalcified paraffin-included sections...
December 2017: International Journal of Implant Dentistry
https://www.readbyqxmd.com/read/28634415/force-induced-increased-osteogenesis-enables-accelerated-orthodontic-tooth-movement-in-ovariectomized-rats
#11
Qinggang Dai, Siru Zhou, Peng Zhang, Xuhui Ma, Nayong Ha, Xiao Yang, Zhifeng Yu, Bing Fang, Lingyong Jiang
As the number of elderly orthodontic patients increases, the impact of postmenopausal osteoporosis on orthodontic tooth movement (OTM) has attracted a great deal of attention because OTM relies on alveolar bone remodeling. The question of whether OTM causes subsequent alveolar bone loss and is harmful to alveolar bone health under osteoporotic conditions remains to be answered. The present study aimed to clarify the influences of OTM on alveolar bone in osteoporotic rats. OTM was accelerated in ovariectomized (OVX) rats as a result of increased bone resorption in the pressure area...
June 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28617966/analysis-of-the-association-of-clinical-factors-and-il4-gene-polymorphisms-with-root-resorption-in-avulsed-teeth-after-1-year-of-replantation
#12
L Roskamp, P C Trevilatto, C M Souza, U X Silva Neto, E Carneiro, L F Fariniuk, V P D Westphalen
AIM: To investigate the association of clinical variables and polymorphisms (tag SNPs) in the interleukin 4 (IL4) gene, with the prognosis of avulsed and replanted teeth. METHODOLOGY: Ninety-four patients who suffered avulsion and had their teeth replanted and endodontically treated were included. Periapical radiographs were obtained soon after tooth replantation and after 1 year. For genotypic IL4 gene analysis, the DNA of the oral mucosa cells was collected, and polymorphisms investigated by Real Time-PCR...
June 15, 2017: International Endodontic Journal
https://www.readbyqxmd.com/read/28612428/outcomes-and-prognostic-factors-that-influence-the-success-of-tooth-autotransplantation-in-children-and-adolescents
#13
Vasiliki Kafourou, Huei Jinn Tong, Peter Day, Nadine Houghton, R James Spencer, Monty Duggal
BACKGROUND/AIM: Tooth autotransplantation has been advocated for replacement of missing teeth or teeth that are unsuitable for restoration. The aim of this study was to investigate the outcomes and prognostic factors that influenced the success of tooth transplantation in a paediatric population. MATERIALS AND METHODS: Data were extracted from the records of 75 patients (89 teeth). Demographic and prognostic factors were recorded and analysed for the clinical and radiographic outcomes for periodontal ligament (PDL) and pulp healing of transplanted teeth...
June 14, 2017: Dental Traumatology: Official Publication of International Association for Dental Traumatology
https://www.readbyqxmd.com/read/28609508/evaluation-of-the-bone-regenerating-effects-of-two-anorganic-bovine-bone-grafts-in-a-critical-sized-alveolar-ridge-defect-model
#14
David M Kim, Heather Hong, Jerry Ching-Yi Lin, Myron Nevins
A preclinical trial was conducted to treat 54 mandibular critical-sized alveolar ridge defects in 27 canines. Each hemimandible was randomized to be treated with two different anorganic bovine bone grafts (group A = InterOss [SigmaGraft]; group B = Bio-Oss [Geistlich]) or negative control (group C = empty defect) followed by a 4-, 8-, or 12-week observation period. Microcomputed tomography, histology, histopathology, and histomorphometric analyses were performed to evaluate the safety and efficacy of these treatments...
July 2017: International Journal of Periodontics & Restorative Dentistry
https://www.readbyqxmd.com/read/28606827/a-new-method-of-volumetric-assessment-of-alveolar-bone-grafting-for-cleft-patients-using-cone-beam-computed-tomography
#15
Bin Feng, Meng Jiang, Xue Xu, Jingtao Li
OBJECTIVE: The aims of this study were to propose a new method for volumetric assessment of alveolar bone grafting and to quantitatively assess alveolar bone grafting based on this method. STUDY DESIGN: Cone beam computed tomography images of 18 patients with unilateral cleft alveolus were selected. Volume of the alveolar cleft before grafting operation (VOLcleft), graft bone filled into cleft immediately after operation (VOLgraft), and bony bridge formed 1 year after operation (VOLbridge) were obtained...
April 19, 2017: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/28597838/-collaboration-between-periodontics-and-orthodontics-interest-of-alveolar-corticotomies-and-piezocision-review-of-literature
#16
Brenda Mertens, Charles Angioni, Valérie Orti, Pierre Canal
INTRODUCTION: Orthodontics in adults must adapt to certain particularities especially related to the decrease or absence of growth and the prevalence of periodontal damage in this population. This review of the literature aims to assess the effects of alveolar corticotomies on accelerating or facilitating tooth movements in different types of orthodontic movements, to compare results obtained by classical technique with those obtained by piezocision and analyze their impact on periodontal tissues in the long term...
June 2017: L' Orthodontie Française
https://www.readbyqxmd.com/read/28597837/-effectiveness-of-selective-alveolar-decortication-in-accelerating-orthodontic-treatment-a-systematic-review
#17
Victor Fau, Dany Diep, Gérard Bader, Damien Brézulier, Olivier Sorel
INTRODUCTION: The number of scientific publications on accelerating orthodontic treatment, and especially surgical alveolar corticotomies techniques, has grown exponentially over the years. The objective of this systematic literature review was to assess the effectiveness of these corticotomies basing on human studies. MATERIAL AND METHOD: The review was conducted from Medline and Web of Science Core Collection to identify prospective controlled clinical trials with duration of orthodontic treatment or the tooth movement rate for primary endpoint...
June 2017: L' Orthodontie Française
https://www.readbyqxmd.com/read/28596739/rank-rankl-opg-signalization-implication-in-periodontitis-new-evidence-from-a-rank-transgenic-mouse-model
#18
Bouchra Sojod, Danielle Chateau, Christopher G Mueller, Sylvie Babajko, Ariane Berdal, Frédéric Lézot, Beatriz Castaneda
Periodontitis is based on a complex inflammatory over-response combined with possible genetic predisposition factors. The RANKL/RANK/OPG signaling pathway is implicated in bone resorption through its key function in osteoclast differentiation and activation, as well as in the inflammatory response. This central element of osteo-immunology has been suggested to be perturbed in several diseases, including periodontitis, as it is a predisposing factor for this disease. The aim of the present study was to validate this hypothesis using a transgenic mouse line, which over-expresses RANK (R(Tg)) and develops a periodontitis-like phenotype at 5 months of age...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28573552/autogenous-bone-grafts-in-oral-implantology-is-it-still-a-gold-standard-a-consecutive-review-of-279-patients-with-456-clinical-procedures
#19
Andreas Sakkas, Frank Wilde, Marcus Heufelder, Karsten Winter, Alexander Schramm
BACKGROUND: This study assessed the clinical outcomes of graft success rate and early implant survival rate after preprosthetic alveolar ridge reconstruction with autologous bone grafts. METHODS: A consecutive retrospective study was conducted on all patients who were treated at the military outpatient clinic of the Department of Oral and Plastic Maxillofacial Surgery at the military hospital in Ulm (Germany) in the years of 2009 until 2011 with autologous bone transplantation prior to secondary implant insertion...
December 2017: International Journal of Implant Dentistry
https://www.readbyqxmd.com/read/28573052/decoronation-an-alternative-treatment-for-replacement-root-resorption
#20
Marianne Sala, Asunción Mendoza-Mendoza, Rosa-María Yañez-Vico
INTRODUCTION: Ankylosis and disrupted or altered root development are frequent complications associated with intrusive luxation and tooth avulsion lesions. Various forms of treatment have been described according to the severity of the trauma and root development. The literature shows that decoronation is an ideal treatment in cases where replacement resorption occurs. METHODS: Two clinical cases are presented: involving intrusive luxation [15-year-old female patient with an affected maxillary left lateral incisor (2...
2017: Case Reports in Dentistry
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