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https://www.readbyqxmd.com/read/27911219/anxiety-mediates-the-relation-between-childhood-sexual-abuse-and-genito-pelvic-pain-in-adolescent-girls
#1
Marie Santerre-Baillargeon, Pascale Vézina-Gagnon, Isabelle Daigneault, Tina Landry, Sophie Bergeron
Previous research has demonstrated associations between child sexual abuse, anxiety and genito-pelvic pain, but no study to date has examined whether sexual abuse may be associated with genito-pelvic pain through victims' elevated anxiety. The present study aimed to determine whether anxiety mediates the relationship between child sexual abuse and genito-pelvic pain. Using self-report questionnaires, data were gathered from 218 sexually active adolescent girls recruited from seven metropolitan high schools...
December 2, 2016: Journal of Sex & Marital Therapy
https://www.readbyqxmd.com/read/27910804/sudden-cardiac-death-a-nationwide-cohort-study-among-the-young
#2
Bjarke Risgaard
Sudden cardiac death (SCD) is a tragic event affecting millions of individuals worldwide. Although several studies have investigated the epidemiology of SCD, these studies may have been affected by reporting and referral biases, which are reflected in the very different incidence rates and causes of deaths that have previously been reported. Among SCD victims aged < 36 years, inherited cardiac diseases are well known to play an important role. However, the extent to which inherited cardiac diseases also play a role in SCD victims aged < 50 years has not been completely described...
December 2016: Danish Medical Journal
https://www.readbyqxmd.com/read/27910730/retrospective-use-of-pbpk-modelling-to-understand-a-clinical-drug-drug-interaction-between-dextromethorphan-and-gsk1034702
#3
Michael J Hobbs, Jackie Bloomer, Gordon Dear
: 1. PURPOSE: In a clinical trial, a strong drug-drug interaction (DDI) was observed between dextromethorphan (DM, the object or victim drug) and GSK1034702 (the precipitant or perpetrator drug), following single and repeat doses. This study determined the inhibition parameters of GSK1034702 in vitro and applied PBPK modelling approaches to simulate the clinical observations and provide mechanistic hypotheses to understand the DDI. 2. METHODS: In vitro assays were conducted to determine the inhibition parameters of human CYP2D6 by GSK1034702...
December 2, 2016: Xenobiotica; the Fate of Foreign Compounds in Biological Systems
https://www.readbyqxmd.com/read/27910059/gene-therapy-for-post-infarction-ventricular-tachycardia
#4
J Kevin Donahue
Cardiac arrhythmias are a leading cause of morbidity and mortality in the developed world. In particular, cardiac arrest or sudden cardiac death is the leading cause of death in these countries. Death generally results from a ventricular tachyarrhythmia, and pathology data have shown that cardiac arrest victims very frequently have evidence of coronary atherosclerosis with either acute ischemia or healed myocardial infarction. In this work, we describe an animal model that reproducibly has inducible ventricular tachyarrhythmias after healing of a myocardial infarction scar and a gene delivery method that allows gene transfer to the scar and surrounding myocardial tissues...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/27909452/the-levels-of-cortisol-and-oxidative-stress-and-dna-damage-in-child-and-adolescent-victims-of-sexual-abuse-with-or-without-post-traumatic-stress-disorder
#5
Şeref Şimşek, Tuğba Yüksel, İbrahim Kaplan, Cem Uysal, Hüseyin Aktaş
OBJECTIVE: The aim of this study was to investigate whether cortisol and oxidative stress levels and DNA damage differ between individuals who developed PTSD or not following a sexual trauma. METHODS: The study included 61 children aged between 5 and 17 years who sustained sexual abuse (M/F: 18/43). The patients were divided into two groups: patients with PTSD and patients without PTSD based, based on the results of a structured psychiatric interview (K-SADS-PL and CAPS-CA)...
November 2016: Psychiatry Investigation
https://www.readbyqxmd.com/read/27909179/disclosure-recipients-social-reactions-to-victims-disclosures-of-intimate-partner-violence
#6
Katie M Edwards, Christina M Dardis
Prior research indicates that victims of intimate partner violence (IPV) are most likely to disclose their victimization experiences to an informal support (e.g., friend, family), and that IPV disclosures are often met with both positive (e.g., empathic support) and negative (e.g., victim blame) reactions. However, research on social reactions to disclosure largely has neglected the perspectives of disclosure recipients. Guided by the attribution framework, the current study extends prior research by assessing factors (i...
November 30, 2016: Journal of Interpersonal Violence
https://www.readbyqxmd.com/read/27909178/no-differences-in-health-outcomes-after-routine-inquiry-about-violence-victimization-in-young-women-a-randomized-controlled-study-in-swedish-youth-health-centers
#7
Anna Palm, Ulf Högberg, Niclas Olofsson, Alkistis Skalkidou, Ingela Danielsson
Youth is a period in life when the risk of violence victimization is high and association between victimization and ill health is well established. Youth rarely reveal violence victimization to health professionals if not directly asked but favor health professionals asking about victimization. The study's primary aim was to examine health outcomes in young women being routinely asked about violence victimization and offered subsequent support, compared with controls, at 12-month follow-up. Secondary aims were to examine to what extent routine inquiry altered the consultation and re-victimization rates during the study period...
November 30, 2016: Journal of Interpersonal Violence
https://www.readbyqxmd.com/read/27908449/gender-differences-in-the-association-between-childhood-sexual-abuse-and-risky-sexual-behaviours-a-systematic-review-and-meta-analysis
#8
Amanuel Alemu Abajobir, Steve Kisely, Joemer Calderon Maravilla, Gail Williams, Jake Moses Najman
This meta-analytic review examines the association between childhood sexual abuse and risky sexual behaviours with sub-group analyses by gender. Systematic searches of electronic databases including MEDLINE, PubMed, EMBASE, and PsycINFO were performed using key terms. We used a priori criteria to include high quality studies and control for heterogeneities across eligible studies. The review was registered with PROSPERO and used the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines...
November 28, 2016: Child Abuse & Neglect
https://www.readbyqxmd.com/read/27907810/prediction-of-autosomal-str-typing-success-in-ancient-and-second-world-war-bone-samples
#9
Irena Zupanič Pajnič, Tomaž Zupanc, Jože Balažic, Živa Miriam Geršak, Oliver Stojković, Ivan Skadrić, Matija Črešnar
Human-specific quantitative PCR (qPCR) has been developed for forensic use in the last 10 years and is the preferred DNA quantification technique since it is very accurate, sensitive, objective, time-effective and automatable. The amount of information that can be gleaned from a single quantification reaction using commercially available quantification kits has increased from the quantity of nuclear DNA to the amount of male DNA, presence of inhibitors and, most recently, to the degree of DNA degradation. In skeletal remains samples from disaster victims, missing persons and war conflict victims, the DNA is usually degraded...
November 19, 2016: Forensic Science International. Genetics
https://www.readbyqxmd.com/read/27907232/analyzing-and-interpreting-lime-burials-from-the-spanish-civil-war-1936-1939-a-case-study-from-la-carcavilla-cemetery
#10
Eline M J Schotsmans, Almudena García-Rubio, Howell G M Edwards, Tasnim Munshi, Andrew S Wilson, Luis Ríos
Over 500 victims of the Spanish Civil War (1936-1939) were buried in the cemetery of La Carcavilla (Palencia, Spain). White material, observed in several burials, was analyzed with Raman spectroscopy and powder XRD, and confirmed to be lime. Archaeological findings at La Carcavilla's cemetery show that the application of lime was used in an organized way, mostly associated with coffinless interments of victims of Francoist repression. In burials with a lime cast, observations made it possible to draw conclusions regarding the presence of soft tissue at the moment of deposition, the sequence of events, and the presence of clothing and other evidence...
December 1, 2016: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/27906642/associations-between-alcohol-use-and-intimate-partner-violence-among-men-who-have-sex-with-men
#11
Alissa Davis, Farnaz Kaighobadi, Rob Stephenson, Christine Rael, Theodorus Sandfort
PURPOSE: Intimate partner violence (IPV) research among men who have sex with men (MSM) has primarily focused on the prevalence of IPV victimization and perpetration. Although alcohol use is a known trigger of IPV in opposite sex relationships, less is known about alcohol use and IPV perpetration and victimization in same-sex couples. The aim of this study was to examine associations between alcohol use and different types of IPV victimization and perpetration among MSM. METHODS: MSM in New York City were recruited at gay-friendly venues and events to participate in an online survey assessing sociodemographics, alcohol use, and victimization/perpetration of IPV with both regular and casual sex partners...
December 2016: LGBT Health
https://www.readbyqxmd.com/read/27905952/mental-health-and-urban-living-in-sub-saharan-africa-major-depressive-episodes-among-the-urban-poor-in-ouagadougou-burkina-faso
#12
Géraldine Duthé, Clémentine Rossier, Doris Bonnet, Abdramane Bassiahi Soura, Jamaica Corker
BACKGROUND: In sub-Saharan African cities, the epidemiological transition has shifted a greater proportion of the burden of non-communicable diseases, including mental and behavioral disorder, to the adult population. The burden of major depressive disorder and its social risk factors in the urban sub-Saharan African population are not well understood and estimates vary widely. We conducted a study in Ouagadougou, Burkina Faso, in order to estimate the prevalence of major depressive episodes among adults in this urban setting...
May 5, 2016: Population Health Metrics
https://www.readbyqxmd.com/read/27905938/the-impact-of-epidemics-on-labor-market-identifying-victims-of-the-middle-east-respiratory-syndrome-in-the-korean-labor-market
#13
Ayoung Lee, Joonmo Cho
BACKGROUND: The vulnerability approach suggests that disasters such as epidemics have different effects according not only to physical vulnerability but also to economic class (status). This paper examines the effect of the Middle East Respiratory Syndrome epidemic on the labor market to investigate whether vulnerable groups become more vulnerable due to an interaction between the socio-economic structure and physical risk. METHODS: This paper examines the effect of the Middle East Respiratory Syndrome epidemic on the labor market by considering unemployment status, job status, working hours, reason for unemployment and underemployment status...
December 1, 2016: International Journal for Equity in Health
https://www.readbyqxmd.com/read/27904168/care-situation-for-female-victims-of-sexual-violence-in-metropolitan-emergency-departments-with-charit%C3%A3-berlin-as-an-example
#14
H Hoffmann-Walbeck, M Möckel, S Etzold, M David
of the perpetrators were friends or relations; 17 % were (ex-)partners. The waiting time in the Charité emergency departments amounted to 58 minutes on average, the medical treatment time 55 minutes. About 80 % of the personnel evaluated the "stuprum kit" as being altogether good or very good. More than ⅓ considered the time and room conditions as being unsuitable or rather unsuitable for the situation. Two thirds expressed the desire for further training and supervision. Conclusion: The structured procedure by means of the "stuprum kit" has proved its value...
November 2016: Geburtshilfe und Frauenheilkunde
https://www.readbyqxmd.com/read/27903992/a-brief-review-on-toxic-alcohols-management-strategies
#15
Hossein Hassanian-Moghaddam, Nasim Zamani
The information on burden of alcohol abuse in Iran is scarce. However, the available data show that mortality rates and frequency of its use have increased in the Iranian community. In particular, Iran occupies the 1st rank in the number of outbreak incidents and victims of toxic alcohols such as methanol in the Middle East. Mortality and morbidity of toxic alcohols are high if prompt diagnosis and treatment are not initiated rapidly. On-time diagnosis, proper case finding, and standard treatment have an essential role to reduce mortality and morbidity of toxic alcohols particularly blindness and other physical and psychological disabilities...
November 2016: Iranian Journal of Kidney Diseases
https://www.readbyqxmd.com/read/27903769/education-for-the-next-frontier-in-patient-safety-a-longitudinal-resident-curriculum-on-diagnostic-error
#16
Emily Ruedinger, Maren Olson, Justin Yee, Emily Borman-Shoap, Andrew P J Olson
Diagnostic error is a common, serious problem that has received increased attention recently for its impact on both patients and providers. Presently, most graduate medical education programs do not formally address this topic. The authors developed and evaluated a longitudinal, multimodule resident curriculum about diagnostic error and medical decision making. Key components of the curriculum include demystifying the medical decision-making process, building skills in critical thinking, and providing strategies for diagnostic error mitigation...
November 29, 2016: American Journal of Medical Quality: the Official Journal of the American College of Medical Quality
https://www.readbyqxmd.com/read/27902668/pneumatosis-intestinalis-due-to-child-abuse
#17
Stephanie Anne Deutsch, Cindy W Christian
Pneumatosis intestinalis (PI) and the presence of portal venous gas (PVG) are commonly considered pathognomonic for necrotizing enterocolitis in the neonatal period; however, these 2 radiographic findings have been documented in all age groups in a variety of clinical settings and medical conditions including respiratory, cardiac, rheumatologic, gastrointestinal disorders, and traumatic injury. In children, intramural dissection of intestinal gas in the absence of clinical symptoms suggestive of necrotizing enterocolitis should raise concern for a traumatic etiology, including injuries sustained from child physical abuse...
November 29, 2016: Pediatric Emergency Care
https://www.readbyqxmd.com/read/27902127/child-abuse-inquiry-urges-nurses-to-help-survivors-tell-their-stories
#18
Flavia Munn
Nurses, midwives and health visitors encounter victims of historical and current abuse in a variety of healthcare settings and specialties. The Independent Inquiry into Child Sexual Abuse, which is looking at the extent to which institutions and organisations in England and Wales have failed to protect children from sexual abuse, wants nurses' help in supporting patients who may have information to contribute.
November 30, 2016: Nursing Standard
https://www.readbyqxmd.com/read/27901254/high-prevalence-of-neuropathic-pain-in-the-hand-of-patients-with-traumatic-brachial-plexus-injury-a-cross-sectional-study
#19
Marcus V B Santana, Mauro T Bina, Matheus G Paz, Scheila N Santos, Manoel J Teixeira, Irina Raicher, José V Martins, Daniel C Araujo Andrade, Abrahão F Baptista
Objective: To describe the pain profile of patients with traumatic brachial plexus injury. Methods: We enrolled 65 patients with traumatic brachial plexus injury. The Douleur Neuropathique 4 questionnaire was used to classify pain and the SF-36 was used to evaluate quality of life. Results: The patients with traumatic brachial plexus injury were predominantly young male victims of motorcycle accidents. Pain was present in 75.4% of the individuals and 79% presented with neuropathic pain, mostly located in the hands (30...
November 2016: Arquivos de Neuro-psiquiatria
https://www.readbyqxmd.com/read/27900669/disruptive-behaviour-in-the-perioperative-setting-a-contemporary-review
#20
Alexander Villafranca, Colin Hamlin, Stephanie Enns, Eric Jacobsohn
PURPOSE: Disruptive behaviour, which we define as behaviour that does not show others an adequate level of respect and causes victims or witnesses to feel threatened, is a concern in the operating room. This review summarizes the current literature on disruptive behaviour as it applies to the perioperative domain. SOURCE: Searches of MEDLINE(®), Scopus™, and Google books identified articles and monographs of interest, with backreferencing used as a supplemental strategy...
November 29, 2016: Canadian Journal of Anaesthesia, Journal Canadien D'anesthésie
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