keyword
https://read.qxmd.com/read/38466259/frequency-specific-effects-of-noninvasive-median-nerve-stimulation-on-gastric-slow-wave-activity-in-humans
#21
JOURNAL ARTICLE
Elliot Thomas Hendry, Joseph Gonzales Balfe, Peng Du, Yusuf Ozgur Cakmak
OBJECTIVES: The present study explored the effects of different frequencies of noninvasive median nerve stimulation (nMNS) on two autonomic responses: gastric slow waves under water-loading condition and heart rate variability (HRV). To the best of our knowledge, this is the first study to document the effects of different frequencies of nMNS on gastric slow waves (GSW) in humans under 5-minute water-loading condition. MATERIALS AND METHODS: Twenty healthy adult participants were fitted with a noninvasive body-surface gastric mapping, electrocardiogram (ECG), and a transcutaneous electrical nerve stimulation device and administered with four different nMNS frequencies (placebo-0 Hz, 40 Hz, 120 Hz, and 200 Hz) on four separate counterbalanced days...
March 11, 2024: Neuromodulation: Journal of the International Neuromodulation Society
https://read.qxmd.com/read/38463497/a-new-method-of-modeling-the-multi-stage-decision-making-process-of-crt-using-machine-learning-with-uncertainty-quantification
#22
Kristoffer Larsen, Chen Zhao, Joyce Keyak, Qiuying Sha, Diana Paez, Xinwei Zhang, Guang-Uei Hung, Jiangang Zou, Amalia Peix, Weihua Zhou
AIMS: The purpose of this study is to create a multi-stage machine learning model to predict cardiac resynchronization therapy (CRT) response for heart failure (HF) patients. This model exploits uncertainty quantification to recommend additional collection of single-photon emission computed tomography myocardial perfusion imaging (SPECT MPI) variables if baseline clinical variables and features from electrocardiogram (ECG) are not sufficient. METHODS: 218 patients who underwent rest-gated SPECT MPI were enrolled in this study...
February 20, 2024: ArXiv
https://read.qxmd.com/read/38451349/subacute-exposure-to-gaseous-pollutants-from-diesel-engine-exhaust-attenuates-capsaicin-induced-cardio-pulmonary-reflex-responses-involving-oxidant-stress-mechanisms-in-adult-wistar-rats
#23
JOURNAL ARTICLE
Ravindran Revand, Aditya Dontham, Swarnabha Sarkar, Asmita Patil
Intravenous injection of capsaicin produces vagal-mediated protective cardio-pulmonary (CP) reflexes manifesting as tachypnea, bradycardia, and triphasic blood pressure (BP) response in anesthetized rats. Particulate matter from diesel engine exhaust has been reported to attenuate these reflexes. However, the effects of gaseous constituents of diesel exhaust are not known. Therefore, the present study was designed to investigate the effects of gaseous pollutants in diesel exhaust, on capsaicin-induced CP reflexes in rat model...
March 7, 2024: Cardiovascular Toxicology
https://read.qxmd.com/read/38445541/the-myeloperoxidase-inhibitor-mitiperstat-azd4831-does-not-prolong-the-qt-interval-at-expected-therapeutic-doses
#24
RANDOMIZED CONTROLLED TRIAL
Joanna Parkinson, Jesper Sundell, Dinko Rekić, Karin Nelander, Hans Ericsson, Ahmad Ebrahimi, Corina Dota, Mikael Sunnåker
Mitiperstat is a myeloperoxidase inhibitor in clinical development for treatment of patients with heart failure and preserved or mildly reduced ejection fraction, non-alcoholic steatohepatits and chronic obstructive pulmonary disease. We aimed to assess the risk of QT-interval prolongation with mitiperstat using concentration-QT (C-QT) modeling. Healthy male volunteers were randomized to receive single oral doses of mitiperstat 5, 15, 45, 135, or 405 mg (n = 6 per dose) or matching placebo (n = 10) in a phase 1 study (NCT02712372)...
April 2024: Pharmacology Research & Perspectives
https://read.qxmd.com/read/38442390/heart-rate-reduction-during-voluntary-deep-diving-in-free-ranging-loggerhead-sea-turtles
#25
JOURNAL ARTICLE
Ayaka Saito, Chihiro Kinoshita, Kino Sakai, Katsufumi Sato, Kentaro Q Sakamoto
Air-breathing vertebrates exhibit cardiovascular responses to diving including heart rate reduction (diving bradycardia). Field studies on aquatic mammals and birds have shown that the intensity of bradycardia can vary depending on diving behaviour, such as the depth of dives and dive duration. However, in aquatic reptiles, the variation in heart rate during deep dives under natural conditions has not been fully investigated. In this study, we released five loggerhead sea turtles (Caretta caretta) outfitted with recorders into the sea and recorded their electrocardiogram, depth, water temperature and longitudinal acceleration...
March 1, 2024: Journal of Experimental Biology
https://read.qxmd.com/read/38441204/wearable-sensors-to-measure-the-influence-of-sonic-seasoning-on-wine-consumers-in-a-live-context-a-preliminary-proof-of-concept-study
#26
JOURNAL ARTICLE
Lucia Billeci, Chiara Sanmartin, Alessandro Tonacci, Isabella Taglieri, Giuseppe Ferroni, Roberto Marangoni, Francesca Venturi
BACKGROUND: Any action capable of creating expectations about product quality would be able to modulate experienced pleasantness. In this context, during the 2022 edition of the Internet Festival (Pisa, Italy) a 'social experiment' was promoted to set up an affordable and reliable methodology based on wearable sensors to measure the emotions aroused in a live context on consumers by different kinds of wines. Therefore, 5 wines (two faulty ones and three high quality samples) were proposed to 50 non-selected consumers in an arousing context with live jazz music as background...
March 5, 2024: Journal of the Science of Food and Agriculture
https://read.qxmd.com/read/38440348/acute-combined-effects-of-concurrent-physical-activities-on-autonomic-nervous-activation-during-cognitive-tasks
#27
JOURNAL ARTICLE
Shan Cheng, Wenbin Li, Duoduo Hui, Jin Ma, Taihui Zhang, Chaolin Teng, Weitao Dang, Kaiwen Xiong, Wendong Hu, Lin Cong
Backgrounds: The validity of heart rate variability (HRV) has been substantiated in mental workload assessments. However, cognitive tasks often coincide with physical exertion in practical mental work, but their synergic effects on HRV remains insufficiently established. The study aims were to investigate the combined effects of cognitive and physical load on autonomic nerve functions. Methods: Thirty-five healthy male subjects (aged 23.5 ± 3.3 years) were eligible and enrolled in the study. The subjects engaged in n-back cognitive tasks (1-back, 2-back, and 3-back) under three distinct physical conditions, involving isotonic contraction of the left upper limb with loads of 0 kg, 3 kg, and 5 kg...
2024: Frontiers in Physiology
https://read.qxmd.com/read/38436059/activation-of-cardiac-parasympathetic-and-sympathetic-activity-occur-at-different-skin-temperatures-during-face-cooling
#28
JOURNAL ARTICLE
Felipe Gorini Pereira, Muhamed McBryde, Morgan Reynolds, James R Sackett, Christopher L Chapman, Elizabeth A Gideon, Zachary J Schlader, Blair D Johnson
Sufficiently cold-water temperatures (<7o C) are needed to elicit the sympathetic response to the cold pressor test using the hand. However, it is not known if stimulating the trigeminal nerve via face cooling, which increases both sympathetic and cardiac parasympathetic activity, also has a threshold temperature. We tested the hypothesis that peak autonomic activation during a progressive face cooling challenge would be achieved when the stimulus temperature is £ 7o C. Twelve healthy participants (age: 25 ± 3 years, 4 women) completed our study...
March 4, 2024: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
https://read.qxmd.com/read/38435599/arrhythmia-classification-for-non-experts-using-infinite-impulse-response-iir-filter-based-machine-learning-and-deep-learning-models-of-the-electrocardiogram
#29
JOURNAL ARTICLE
Mallikarjunamallu K, Khasim Syed
Arrhythmias are a leading cause of cardiovascular morbidity and mortality. Portable electrocardiogram (ECG) monitors have been used for decades to monitor patients with arrhythmias. These monitors provide real-time data on cardiac activity to identify irregular heartbeats. However, rhythm monitoring and wave detection, especially in the 12-lead ECG, make it difficult to interpret the ECG analysis by correlating it with the condition of the patient. Moreover, even experienced practitioners find ECG analysis challenging...
2024: PeerJ. Computer Science
https://read.qxmd.com/read/38425620/myocardial-infarction-simulated-from-improper-telemetry-misfit-an-autobiographical-case-report
#30
Philip R Cohen, Brent M Gudenkauf
An electrocardiogram, used to not only assess the rate and rhythm of the heart but also to evaluate for injury to the heart, is performed by attaching 12 leads to the patient's body. A myocardial infarction can be mimicked by the misplacement of the leads. A 58-year-old man with long-distance running-associated bradycardia developed postoperative atrial fibrillation with a rapid ventricular response. He converted to normal sinus rhythm after a single oral dose of 30 milligrams of diltiazem; however, the automated reading of the electrocardiogram performed in the hospital showed new changes suggestive of a postero-lateral myocardial infarction, including Q waves in leads I and aVL, as well as early precordial R wave progression with R waves and positive T waves in V2 and V3 , and a dominant R wave (R wave to S wave ratio greater than one) in V2 ...
January 2024: Curēus
https://read.qxmd.com/read/38417611/newborn-resuscitation-timelines-accurately-capturing-treatment-in-the-delivery-room
#31
JOURNAL ARTICLE
Hanne Pike, Vilde Kolstad, Joar Eilevstjønn, Peter G Davis, Hege Langli Ersdal, Siren Irene Rettedal
OBJECTIVES: To evaluate the use of newborn resuscitation timelines to assess the incidence, sequence, timing, duration of and response to resuscitative interventions. METHOD: A population-based observational study conducted June 2019 - November 2021 at Stavanger University Hospital, Norway. Parents consented to participation antenatally. Newborns ≥28 weeks' gestation receiving positive pressure ventilation (PPV) at birth were enrolled. Time of birth was registered...
February 26, 2024: Resuscitation
https://read.qxmd.com/read/38416867/a-retrospective-comparison-of-upper-and-lower-extremity-intraosseous-access-during-out-of-hospital-cardiac-arrest-resuscitation
#32
JOURNAL ARTICLE
Tanner Smida, Remle Crowe, Jeffrey Jarvis, Taylor Ratcliff, Mat Goebel
OBJECTIVE: Intraosseous (IO) access is frequently utilized during the resuscitation of out-of-hospital cardiac arrest (OHCA) patients. Due to proximity to the heart and differential flow rates, the anatomical site of IO access may impact patient outcomes. Using a large dataset, we aimed to compare the outcomes of OHCA patients who received upper or lower extremity IO access during resuscitation. METHODS: The ESO Data Collaborative public use research datasets were used for this retrospective study...
February 28, 2024: Prehospital Emergency Care
https://read.qxmd.com/read/38413540/a-randomized-open-label-5-period-crossover-study-evaluating-the-pharmacokinetics-and-safety-of-a-single-dose-of-intranasal-dihydroergotamine-dhe-powder-sts101-intramuscular-dhe-mesylate-and-liquid-nasal-spray-dhe-in-healthy-adults
#33
JOURNAL ARTICLE
Richard B Lipton, Detlef Albrecht, Maria Bermudez, Jerry Hu, Elizabeth Hussey, Jeff Levy
OBJECTIVE: To compare the safety and pharmacokinetics (PK) of dihydroergotamine (DHE) after administration of intranasal DHE powder (STS101), liquid nasal spray (LNS) DHE mesylate, and intramuscular (IM) DHE mesylate injection in healthy participants. BACKGROUND: DHE is an effective acute migraine treatment; however, self-administration difficulties have prevented its broader role in the management of migraine. METHODS: This randomized, active-controlled, five-period crossover study was conducted over 5 weeks separated by 1-week washout periods...
February 27, 2024: Headache
https://read.qxmd.com/read/38409566/evaluation-of-electrocardiogram-parameters-and-heart-rate-variability-during-blood-pressure-elevation-by-phenylephrine-in-cirrhotic-rats
#34
JOURNAL ARTICLE
Farzaneh Ketabchi, Mohammadreza Khoram, Amirreza Dehghanian
Cirrhotic cardiomyopathy is a myocardial disease that may go undetected in the early stages due to peripheral vasodilatation. The aim of the study was to evaluate the electrocardiogram (ECG) and heart rate variability (HRV) after raising blood pressure by phenylephrine injection in rats with liver cirrhosis. Twenty male Sprague-Dawley rats were divided into the Sham and common bile duct ligation (CBDL) groups. After 44 days, animals were anesthetized and the right femoral artery and vein catheterized. After a steady-state period, a bolus injection of phenylephrine (PHE, 10 μg/μl/IV, baroreflex maneuver) was followed by a slow injection of PHE (100 μg/ml/5 min/IV, sustained maneuver)...
February 26, 2024: Cardiovascular Toxicology
https://read.qxmd.com/read/38406842/beating-the-heart-failure-odds-long-term-survival-after-myocardial-ischemia-in-juvenile-rainbow-trout
#35
JOURNAL ARTICLE
Lucas A Zena, Andreas Tommy Ekström, Daniel Morgenroth, Tristan McArley, Michael Axelsson, Henrik Sundh, Anders Palmquist, Ida B Johansen, Albin Gräns, Erik Sandblom
Salmonid fish include some of the most valued cultured fish species worldwide. Unlike most other fish, the hearts of salmonids, including Atlantic salmon and rainbow trout, have a well-developed coronary circulation. Consequently, their hearts' reliance on oxygenation through coronary arteries leaves them prone to coronary lesions, believed to precipitate myocardial ischemia. Here, we mimicked such coronary lesions by subjecting groups of juvenile rainbow trout to coronary ligation, assessing histo-morphological myocardial changes associated with ischemia and scarring in the context of cardiac arrhythmias using electrocardiography (ECG)...
February 26, 2024: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
https://read.qxmd.com/read/38402334/asystole-on-loop-recorder-in-patients-with-unexplained-syncope-and-negative-tilt-testing-age-distribution-and-clinical-predictors
#36
JOURNAL ARTICLE
Vincenzo Russo, Angelo Comune, Erika Parente, Anna Rago, Andrea Antonio Papa, Gerardo Nigro, Michele Brignole
BACKGROUND: Approximately 50% of patients with unexplained syncope and negative head-up tilt test (HUTT) who have an electrocardiogram (ECG) documentation of spontaneous syncope during implantable loop recorder (ILR) show an asystolic pause at the time of the event. OBJECTIVE: The aim of the study was to evaluate the age distribution and clinical predictors of asystolic syncope detected by ILR in patients with unexplained syncope and negative HUTT. METHODS: This research employed a retrospective, single-center study of consecutive patients...
February 25, 2024: Clinical Autonomic Research: Official Journal of the Clinical Autonomic Research Society
https://read.qxmd.com/read/38400504/scalabledigitalhealth-sdh-an-iot-based-scalable-framework-for-remote-patient-monitoring
#37
JOURNAL ARTICLE
Hisham Alasmary
Addressing the increasing demand for remote patient monitoring, especially among the elderly and mobility-impaired, this study proposes the "ScalableDigitalHealth" (SDH) framework. The framework integrates smart digital health solutions with latency-aware edge computing autoscaling, providing a novel approach to remote patient monitoring. By leveraging IoT technology and application autoscaling, the "SDH" enables the real-time tracking of critical health parameters, such as ECG, body temperature, blood pressure, and oxygen saturation...
February 19, 2024: Sensors
https://read.qxmd.com/read/38397269/a-survey-of-the-union-of-european-neonatal-and-perinatal-societies-on-neonatal-respiratory-care-in-neonatal-intensive-care-units
#38
JOURNAL ARTICLE
Corrado Moretti, Camilla Gizzi, Luigi Gagliardi, Flavia Petrillo, Maria Luisa Ventura, Daniele Trevisanuto, Gianluca Lista, Raffaele L Dellacà, Artur Beke, Giuseppe Buonocore, Antonia Charitou, Manuela Cucerea, Boris Filipović-Grčić, Nelly Georgieva Jeckova, Esin Koç, Joana Saldanha, Manuel Sanchez-Luna, Dalia Stoniene, Heili Varendi, Giulia Vertecchi, Fabio Mosca
(1) Background: Our survey aimed to gather information on respiratory care in Neonatal Intensive Care Units (NICUs) in the European and Mediterranean region. (2) Methods: Cross-sectional electronic survey. An 89-item questionnaire focusing on the current modes, devices, and strategies employed in neonatal units in the domain of respiratory care was sent to directors/heads of 528 NICUs. The adherence to the "European consensus guidelines on the management of respiratory distress syndrome" was assessed for comparison...
January 26, 2024: Children
https://read.qxmd.com/read/38394186/household-food-insecurity-is-associated-with-greater-autonomic-dysfunction-testing-score-in-latinos-with-type-2-diabetes
#39
JOURNAL ARTICLE
Angela Bermúdez-Millán, Richard Feinn, Rachel Lampert, Rafael Pérez-Escamilla, Sofia Segura-Pérez, Julie Wagner
AIM: We examined household food insecurity (HFI) and autonomic nervous system (ANS) function in a subset of low-income Latinos with type 2 diabetes with data from a stress management trial. METHODS: InclusionLatino or Hispanic, Spanish speaking, age less than 18 years, ambulatory status, type 2 diabetes more than 6 months, A1c less than 7.0%. ExclusionPain or dysfunction in hands (e.g., arthritis) precluding handgrip testing; medical or psychiatric instability. HFI was assessed with the 6-item U...
2024: PloS One
https://read.qxmd.com/read/38390008/-drug-resistant-pulmonary-tuberculosis-at-maradi-regional-hospital-center-niger-2014-2018
#40
JOURNAL ARTICLE
Mahaman Laouali Harouna Amadou, Ibrahim Maman Lawan, Ousmane Abdoulaye, Abdoul Kadir Ibrahim Mamadou, Oumarou Amadou, Hassane Boureima, Biraima Ahamadou, Nouhou Hama Aghali, Nana Hadiza Abdourahamane Maifada, Abdoulaziz Kabirou Amoussa, Chaibou Maidakouale
AIM OF STUDY: To describe the clinical, therapeutic and evolutionary profile of patients followed for rifampicin-resistant pulmonary tuberculosis (RR-TB) at the Regional Hospital Centre (RHC) of Maradi (Niger) from 2014 to 2018. METHODS: We conducted a retrospective and descriptive study based on the records of patients followed for Multidrug-resistant tuberculosis (MDR-TB) between January 1, 2014 and June 30, 2018 at the resistant tuberculosis management unit in Maradi (Niger)...
December 31, 2023: Med Trop Sante Int
keyword
keyword
76816
2
3
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.