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https://www.readbyqxmd.com/read/29341881/clinical-implications-of-technological-advances-in-screening-for-atrial-fibrillation
#1
REVIEW
Nikhil Singh, Sung Chun, David Hadley, Victor Froelicher
The incidence of atrial fibrillation (AF) continues to increase worldwide as people live longer. AF is the leading cause of stroke among patients older than 75 years and is responsible for at least 15% of all strokes. Industry has responded to this problem with a plethora of monitoring devices. These include single lead ECG adhesive sensors, implantable loop recorders, smartphone attachments and wearables. This review will concentrate on clinical studies using these technologies. There are wearables including watches and watch-like devices that will be mentioned but these have not been validated for clinical use...
January 13, 2018: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/29330154/novel-wearable-seismocardiography-and-machine-learning-algorithms-can-assess-clinical-status-of-heart-failure-patients
#2
Omer T Inan, Maziyar Baran Pouyan, Abdul Q Javaid, Sean Dowling, Mozziyar Etemadi, Alexis Dorier, J Alex Heller, A Ozan Bicen, Shuvo Roy, Teresa De Marco, Liviu Klein
BACKGROUND: Remote monitoring of patients with heart failure (HF) using wearable devices can allow patient-specific adjustments to treatments and thereby potentially reduce hospitalizations. We aimed to assess HF state using wearable measurements of electrical and mechanical aspects of cardiac function in the context of exercise. METHODS AND RESULTS: Patients with compensated (outpatient) and decompensated (hospitalized) HF were fitted with a wearable ECG and seismocardiogram sensing patch...
January 2018: Circulation. Heart Failure
https://www.readbyqxmd.com/read/29321268/computational-techniques-for-ecg-analysis-and-interpretation-in-light-of-their-contribution-to-medical-advances
#3
REVIEW
Aurore Lyon, Ana Mincholé, Juan Pablo Martínez, Pablo Laguna, Blanca Rodriguez
Widely developed for clinical screening, electrocardiogram (ECG) recordings capture the cardiac electrical activity from the body surface. ECG analysis can therefore be a crucial first step to help diagnose, understand and predict cardiovascular disorders responsible for 30% of deaths worldwide. Computational techniques, and more specifically machine learning techniques and computational modelling are powerful tools for classification, clustering and simulation, and they have recently been applied to address the analysis of medical data, especially ECG data...
January 2018: Journal of the Royal Society, Interface
https://www.readbyqxmd.com/read/29315578/hcn4-pacemaker-channels-attenuate-the-parasympathetic-response-and-stabilize-the-spontaneous-firing-of-sinoatrial-node
#4
Yuko Kozasa, Noriyuki Nakashima, Masayuki Ito, Taisuke Ishikawa, Hiroki Kimoto, Kazuo Ushijima, Naomasa Makita, Makoto Takano
The heart rate is dynamically controlled by the sympathetic and parasympathetic nervous systems that regulate the sinoatrial node (SAN). HCN4 pacemaker channels are well-known causative molecule of congenital sick sinus syndrome. Although HCN4 channels are activated by cAMP, the sympathetic response of SAN was preserved in the patients carrying loss-of-function mutations of HCN4 gene. In order to clarify the contribution of HCN4 channels in the autonomic regulation of SAN, we developed novel gain-of-function mutant mice in which expression level of HCN4 channels could be reversibly changed from zero to ∼3 times of that in wild type mice, using tetracycline trans-activator and tetracycline responsive element...
January 9, 2018: Journal of Physiology
https://www.readbyqxmd.com/read/29312704/the-absence-of-effect-of-ganglionated-plexi-ablation-on-heart-rate-variability-parameters-in-patients-after-thoracoscopic-ablation-for-atrial-fibrillation
#5
Jana Zdarska, Pavel Osmancik, Petr Budera, Dalibor Herman, Radka Prochazkova, David Talavera, Zbynek Straka
Background: Hybrid ablation [thoracoscopic ablation (TA) of atrial fibrillation (AF) followed by catheter ablation (CA)] is an increasingly common method of the treatment for patients with AF. The aim of this study was to assess the response to ganglionated plexi (GP) ablation in patients with a previous TA (i.e., to assess whether TA had resulted in damage to the GP. Heart rate variability (HRV) was used as a marker of the autonomic response. Methods: Twenty AF patients underwent pulmonary vein isolation (PVI) plus GP ablation (GP group) and 18 AF patients underwent CA including GP ablation as a part of hybrid ablation (i...
December 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29297735/national-assessment-of-quality-programs-in-emergency-medical-services
#6
Michael Redlener, Patrick Olivieri, George T Loo, Kevin Munjal, Michael T Hilton, Katya Trudeau Potkin, Michael Levy, Jeffrey Rabrich, Michael R Gunderson, Sabina A Braithwaite
OBJECTIVE: This study aims to understand the adoption of clinical quality measurement throughout the United States on an EMS agency level, the features of agencies that do participate in quality measurement, and the level of physician involvement. It also aims to barriers to implementing quality improvement initiatives in EMS. METHODS: A 46-question survey was developed to gather agency level data on current quality improvement practices and measurement. The survey was distributed nationally via State EMS Offices to EMS agencies nation-wide using Surveymonkey©...
January 3, 2018: Prehospital Emergency Care
https://www.readbyqxmd.com/read/29277236/response-to-ecg-december-2017
#7
Pedro Martínez-Losas, Miguel Ángel Cobos Gil
No abstract text is available yet for this article.
January 2018: Revista Española de Cardiología
https://www.readbyqxmd.com/read/29273234/body-surface-activation-mapping-of-electrical-dyssynchrony-in-cardiac-resynchronization-therapy-patients-potential-for-optimization
#8
Alan J Bank, Ryan M Gage, Antonia E Curtin, Kevin V Burns, Jeffrey M Gillberg, Subham Ghosh
BACKGROUND: Electrical synchronization is likely improved by cardiac resynchronization therapy (CRT), but is difficult to quantify with 12-lead ECG. We aimed to quantify changes in electrical synchrony and potential for optimization with CRT using a body-surface activation mapping (BSAM) system. METHODS: Standard deviation of activation times (SDAT) was calculated in 94 patients using BSAM at baseline CRT (CRTbl), native, and different CRT configurations. RESULTS: SDAT decreased 20% from native to CRTbl (p<0...
December 6, 2017: Journal of Electrocardiology
https://www.readbyqxmd.com/read/29249328/monitoring-and-controlling-follicular-activity-in-camelids
#9
Ahmed Tibary
This paper reviews that state of our knowledge concerning follicular wave dynamics, monitoring and manipulation. All camelids have overlapping follicular waves in absence of ovulation which is induced by a seminal plasma factor (βNGF). The interval between follicular waves varies. The size of the ovulatory follicle varies between 11 and 25 mm in camels and between in 6 and 13 mm in South American Camelids. The interval between induction of ovulation and next ovulatory follicle is 15 ± 1 day for all camelids...
December 8, 2017: Theriogenology
https://www.readbyqxmd.com/read/29248384/efficacy-and-tolerability-of-telmisartan-amlodipine-hydrochlorothiazide-versus-telmisartan-amlodipine-combination-therapy-for-essential-hypertension-uncontrolled-with-telmisartan-amlodipine-the-phase-iii-multicenter-randomized-double-blind-tahyti-study
#10
Ki-Chul Sung, Yong-Seog Oh, Dong-Hun Cha, Soon-Jun Hong, Kyung-Heon Won, Ki-Dong Yoo, Seung-Woon Rha, Young-Keun Ahn, Jeong-Cheon Ahn, Ji-Yong Jang, Tack-Jong Hong, Sang-Kyoon Cho, Sang-Ho Park, Min-Su Hyon, Chang-Wook Nam, In-Ho Chae, Byung-Su Yoo, Jong-Min Song, Jin-Ok Jeong, Young Won Yoon, Byung-Soo Kim, Tae-Hyun Yang, Deok-Kyu Cho, Sang-Hyun Kim, Yu-Jeong Choi, Ji-Hun Ahn, Dong-Woon Jeon, Hyo-Soo Kim
PURPOSE: This 8-week study in Korea aimed to evaluate the efficacy and tolerability of a telmisartan/amlodipine + hydrochlorothiazide (TAH) combination versus telmisartan/amlodipine (TA) combination in patients with essential hypertension that did not respond appropriately to 4-week treatment with TA. METHODS: All patients who met the inclusion criteria received TA (40/5 mg) during a 4-week run-in period (period 1). Patients who met the criteria for essential hypertension (mean sitting systolic blood pressure [MSSBP], ≥140 and <200 mm Hg, or ≥130 and<200 mm Hg in those with diabetes mellitus or chronic kidney disease) after period 1 were randomly assigned to receive TA 40/5 mg + hydrochlorothiazide 12...
December 13, 2017: Clinical Therapeutics
https://www.readbyqxmd.com/read/29240450/letter-in-response-to-tp-e-interval-and-tp-e-qt-ratio-before-and-after-catheter-ablation-in-patients-with-premature-ventricular-complexes
#11
Ahmet Korkmaz, Deniz Sahin, Umit Guray
AIM: Recently fragmented QRS (fQRS) on ECG has been introduced as a predictor of myocardial scarring and myocardial ischemia in coronary artery disease. OBJECTIVE: The aim of this study was to investigate the relationship between fQRS and fractional flow reserve (FFR) results in patients with the intermediate degree of coronary artery stenosis. METHODS: A total of 301 consecutive patients who underwent coronary angiography and FFR measurement for intermediate coronary artery stenosis were included in the study...
December 14, 2017: Biomarkers in Medicine
https://www.readbyqxmd.com/read/29240004/synchronizing-gait-with-cardiac-cycle-phase-alters-heart-rate-response-during-running
#12
Keren Constantini, Abigail S L Stickford, Jeffery L Bleich, Paul D Mannheimer, Benjamin D Levine, Robert F Chapman
Timing foot strike to occur in synchrony with cardiac diastole may reduce left ventricular afterload and promote coronary and skeletal muscle perfusion. PURPOSE: To assess heart rate (HR) and metabolic responses to running when foot strikes are timed to occur exclusively during 1) the systolic phase of the cardiac cycle, or 2) the diastolic phase. METHODS: Ten elite male distance runners performed a testing session on a treadmill at 4.72 m[BULLET OPERATOR]s while matching their steps to an auditory tone and wearing a chest strap that transmitted accelerometer and ECG signals...
December 12, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/29233646/induced-brugada-syndrome-possible-sources-of-arrhythmogenesis
#13
REVIEW
Gonçalo Tomé, João Freitas
Brugada syndrome is an inherited cardiac condition with the potential for development of life-threatening arrhythmias in relatively young individuals without significant structural cardiac abnormalities. The condition is characterized by a distinct coved-type ST segment elevation in the right precordial leads (V1-V3). This hallmark pattern (type 1) is often dynamic and sometimes concealed, and may be unmasked in certain conditions or under the effect of certain agents, which include variation of sympathovagal balance, hormones, metabolic factors and drugs...
December 9, 2017: Portuguese Journal of Cardiology: An Official Journal of the Portuguese Society of Cardiology
https://www.readbyqxmd.com/read/29222865/multipoint-pacing-improves-peripheral-hemodynamic-response-non-invasive-assessment-using-radial-artery-tonometry
#14
Giuseppe Ciconte, Žarko Ćalović, Gabriele Vicedomini, Amarild Cuko, Luke C McSpadden, Chunlan Jiang, Kyungmoo Ryu, Igor Caporaso, Robert Stutz, Dean Winter, Massimo Saviano, Raffaele Vitale, Manuel Conti, Vincenzo Santinelli, Carlo Pappone
BACKGOUND: Multipoint left ventricular (LV) pacing (MultiPoint™ Pacing [MPP], Abbott) improves the response rate to cardiac resynchronization therapy (CRT). We evaluated the feasibility of non-invasive radial artery tonometry (RAT) to characterize arterial pressure morphology changes (pre-ejection period [PEP] and ejection duration [ED]) between conventional CRT and MPP pacing interventions. METHODS: Patients with a MPP-enabled CRT device (Quadra Assura MP™, Abbott) underwent non-invasive RAT assessment (SphygmoCor CVMS, AtCor Medical Inc...
December 9, 2017: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/29214181/cardiac-autonomic-neuropathy-why-should-cardiologists-care-about-that
#15
REVIEW
Andrzej Bissinger
Background: Cardiac autonomic neuropathy (CAN) is a frequent but underdiagnosed complication of diabetes mellitus. It has a strong influence on various cardiac disorders including myocardial ischemia and infarction, hypertension, orthostatic hypotonia, heart failure, and arrhythmias. CAN can lead to severe morbidity and mortality and increase the risk of sudden cardiac death. Methods: This review article summarizes the latest evidence regarding the epidemiology, pathogenesis, influence on the cardiovascular system, and diagnostic methods for CAN...
2017: Journal of Diabetes Research
https://www.readbyqxmd.com/read/29206569/application-of-miniature-heart-rate-data-loggers-for-use-in-large-free-moving-decapod-crustaceans-method-development-and-validation
#16
Iain J McGaw, S Clay Steell, Travis E Van Leeuwen, Erika J Eliason, Steven J Cooke
Cardiovascular responses of decapod crustaceans to environmental challenges have received extensive attention. However, nearly all of these studies have been restricted to lab-based experiments; here we describe a methodology that will enable measurement of heart rate (HR) in free-moving decapods in the field. Data storage tag heart rate and temperature loggers (DST micro-HRT; Star-Oddi) were used to record electrocardiograms (ECG) and HR in large decapod crustaceans. These loggers were originally designed for use in vertebrates and must be surgically implanted in the body cavity near the heart in order to function...
January 2018: Physiological and Biochemical Zoology: PBZ
https://www.readbyqxmd.com/read/29205212/experimental-identification-of-a-mathematical-model-of-human-operator-working-under-mental-stress
#17
Antoni Kopyt, Krystyna Zużewicz, Paweł Bartuzi
In engineering the human is considered as one of the system elements. In most studies, his/her model remains unchanged due to the external factors. The present study shows that a relation between the mental stress and human dynamics cannot be neglected. The dynamic characteristics of the operator model change due to external stimuli, i.e., mental stress. The aim of this study was to present identification of a mathematical human model and measurement methodology of the mental stress level. To determine the level of human response to external stimuli, the electrocardiography (ECG) and electromyography (EMG) methods were applied...
2017: Acta of Bioengineering and Biomechanics
https://www.readbyqxmd.com/read/29198434/response-to-ecg-november-2017
#18
Virginia Ruiz Pizarro, Carlos Nicolás Pérez García, Victoria Cañadas Godoy
No abstract text is available yet for this article.
December 2017: Revista Española de Cardiología
https://www.readbyqxmd.com/read/29189666/validity-of-wearable-activity-monitors-during-cycling-and-resistance-exercise
#19
Benjamin D Boudreaux, Edward P Hebert, Daniel B Hollander, Brian M Williams, Corinne L Cormier, Mildred R Naquin, Wynn W Gillan, Emily E Gusew, Robert R Kraemer
INTRODUCTION: The use of wearable activity monitors has seen rapid growth; however, the mode and intensity of exercise could affect validity of heart rate (HR) and caloric (energy) expenditure (EE) readings. There is a lack of data regarding the validity of wearable activity monitors during graded cycling regimen and a standard resistance exercise. The present study determined the validity of eight monitors for HR compared to an ECG and seven monitors for EE compared to a metabolic analyzer during graded cycling and resistance exercise...
November 7, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/29180164/th-17-cytokines-are-associated-with-severity-of-trypanosoma-cruzi-chronic-infection-in-pediatric-patients-from-endemic-areas-of-mexico
#20
Mariana De Alba-Alvarado, Paz María Salazar-Schettino, Luis Jiménez-Álvarez, Margarita Cabrera-Bravo, Cecilia García-Sancho, Edgar Zenteno, Clara Vazquez-Antona, Alfredo Cruz-Lagunas, Joaquín Zúñiga, Martha Irene Bucio-Torres
In Chagas disease the clinical, acute and chronic manifestations are the result of the interaction between the parasite and the host factors. The balance between inflammatory and anti-inflammatory immune responses is essential for the increase or resolution of the manifestations in individuals infected with T. cruzi. To identify if children with chronic Chagas disease and heart injury is related with non-regulated Th1, Th2 and Th17 responses. We included 31 children with T. cruzi confirmed chronic infection from endemic areas of Mexico...
November 24, 2017: Acta Tropica
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