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https://www.readbyqxmd.com/read/28731780/evaluation-of-turmeric-chip-compared-with-chlorhexidine-chip-as-a-local-drug-delivery-agent-in-the-treatment-of-chronic-periodontitis-a-split-mouth-randomized-controlled-clinical-trial
#1
Abhilasha Singh, Raja Sridhar, Ravi Shrihatti, Akash Mandloy
AIMS AND OBJECTIVE: The aim of this study was to evaluate and compare the effect of chlorhexidine (CHX) chip and turmeric chip as a local drug delivery (LDD) agent in the treatment of patients with chronic periodontitis. MATERIALS AND METHODS: A total of 120 sites with pocket depths 5-8 mm were chosen as a split mouth design at 3 sites in the same patient. Selected sites were randomly divided into three groups to receive CHX chip in addition to scaling and root planing (SRP) in group A, turmeric chip in addition to SRP in group B, and SRP only in group C...
July 21, 2017: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
https://www.readbyqxmd.com/read/28731373/efficacy-of-1-metformin-gel-in-moderate-and-severe-chronic-periodontitis-subjects-a-randomized-controlled-clinical-trial
#2
A R Pradeep, Kaushik Patnaik, Kanika Nagpal, Shruti Karvekar, C N Guruprasad, K M Kumaraswamy
BACKGROUND: To investigate efficacy of MF 1 % gel as, as an adjunct to scaling and root planing (SRP) in treatment of moderate and severe chronic periodontitis subjects. METHODS: Seventy subjects were categorized into two treatment groups: SRP plus 1% MF and SRP plus placebo. Clinical parameters were recorded at baseline, 3, 6 and 9 months; they included plaque index (PI), modified sulcus bleeding index (mSBI), pocket depth (PD), and clinical attachment level (CAL)...
July 21, 2017: Journal of Periodontology
https://www.readbyqxmd.com/read/28726973/heart-rate-variability-biofeedback-stress-relief-program-for-depression-a-replicated-single-subject-design
#3
Bregje M A Hartogs, Agna Bartels-Velthuis, Karen Van der Ploeg, Elske H Bos
BACKGROUND: Depressive disorders often have a chronic course and the efficacy of evidence-based treatments may be overestimated. OBJECTIVE: To examine the effectiveness of the Heart Rate Variability Stress Reduction Program (SRP) as a supplement to standard treatment in patients with depressive disorders. METHODS: The SRP was individually administered in eight weekly sessions. Seven participants completed the full protocol and were enrolled in a single-subject ABA multiple baseline experimental design...
July 19, 2017: Methods of Information in Medicine
https://www.readbyqxmd.com/read/28721992/comparative-evaluation-of-effectiveness-of-intra-pocket-anesthetic-gel-and-injected-local-anesthesia-during-scaling-and-root-planing-a-split-mouth-clinical-trial
#4
Kalyan Chintala, Sandhya Pavan Kumar, K Raja V Murthy
BACKGROUND AND AIM: Pain control is an important outcome measure for successful periodontal therapy. Injected local anesthesia has been used to secure anesthesia for scaling and root planing (SRP) and continues to be the anesthetic of choice for pain control. Alternatively, intra-pocket anesthetic gel has been used as an anesthetic during SRP. Hence, this clinical trial was done to compare the effectiveness of intra-pocket anesthetic gel and injected local anesthesia during SRP and also to assess the influence of intra-pocket anesthetic gel on treatment outcomes in chronic periodontitis patients...
May 2017: Indian Journal of Dental Research: Official Publication of Indian Society for Dental Research
https://www.readbyqxmd.com/read/28720599/hyperacute-muscle-weakness-in-an-unusual-coexistence-of-antisignal-recognition-particle-and-anti-mi-2-antibodies
#5
Richard Oluyinka Akintayo, Olanrewaju Festus Agbola, Abiodun Waliyullah Adeyemo, Olufemi Adelowo
Idiopathic inflammatory myopathies are a heterogeneous group of systemic diseases characterised by variable phenotypes of chronic progressive muscle weakness. Myositis-specific antibodies (MSAs) include antibodies to cytoplasmic signal recognition particle (SRP) and various tRNA synthetases as well as the nuclear helicase protein Mi-2. These antibodies are typically found only in a fraction of true myositis cases and they tend to be mutually exclusive. Few cases of coexistence of two MSAs in the same patient have been reported and these cases all involve an antisynthetase antibody coexisting with either anti-SRP or anti-Mi-2 antibody...
July 18, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28717093/paraneoplastic-anti-3-hydroxy-3-methylglutary-coenzyme-a-reductase-antibody-positive-immune-mediated-necrotizing-myopathy-in-a-patient-with-uterine-cancer
#6
Atsushi Mizuma, Maiko Kouchi, Shizuka Netsu, Sachiko Yutani, Ruriko Kitao, Shigeaki Suzuki, Kenya Murata, Eiichiro Nagata, Shunya Takizawa
We report the case of a 69-year-old woman with proximal limb muscle weakness, who received post-operative chemotherapy for uterine cancer. Her serum creatinine kinase level was high (10,779 mg/dL) and a muscle biopsy from her left biceps revealed various sizes of muscle fibers accompanied by necrotic and regenerating fibers. She was positive for anti-3 hydroxy-3-methylglutary-coenzyme A reductase (anti-HMGCR) antibodies, but negative for anti-signal recognition particle (anti-SRP) antibodies. She was diagnosed with immune-mediated necrotizing myopathy (IMNM) and treated with prednisolone...
2017: Internal Medicine
https://www.readbyqxmd.com/read/28710428/the-use-of-a-hybrid-sequential-biofiltration-system-for-the-improvement-of-nutrient-removal-and-pcb-control-in-municipal-wastewater
#7
Edyta Kiedrzyńska, Magdalena Urbaniak, Marcin Kiedrzyński, Adam Jóźwik, Agnieszka Bednarek, Ilona Gągała, Maciej Zalewski
This article aims to evaluate the efficiency of an innovative hybrid Sequential Biofiltration System (SBS) for removing phosphorus and nitrogen and polychlorinated biphenyls (PCBs) from original municipal wastewater produced by a Wastewater Treatment Plant under authentic operating conditions. The hybrid SBS was constructed with two barriers, a geochemical (filtration beds with limestone, coal and sawdust) and a biological barrier (wetlands with Glyceria, Acorus, Typha, Phragmites), operating in parallel. Significant differences were found between inflow and outflow from the SBS with regard to wastewater contaminant concentrations, the efficiency of removal being 16% (max...
July 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28706787/effect-of-scaling-root-planing-on-the-activity-of-alp-in-gcf-serum-of-patients-with-gingivitis-chronic-and-aggressive-periodontitis-a-comparative-study
#8
Nishi Singh, Siddhartha Chandel, Harmurti Singh, Amiya Agrawal, A N Savitha
INTRODUCTION: Host response and environmental factors are known to modify periodontal status adversely. Presently serum, saliva, and GCF are being investigated for its biochemical constituents. GCF contains array of biochemical factors, offering potential use as a diagnostic or prognostic biomarker of the biologic state of the periodontium in health and disease. Alkaline phosphatase is produced locally in the periodontium and shows positive correlation with disease activity and PD. Present study was designed to analyze the levels of ALP in GCF and serum of patients with gingivitis, chronic & aggressive periodontitis before and after SRP & to compare the difference within the study groups...
May 2017: Journal of Oral Biology and Craniofacial Research
https://www.readbyqxmd.com/read/28692925/role-of-the-adjunctive-antimicrobial-photodynamic-therapy-to-periodontal-treatment-at-plasmatic-oxidative-stress-and-vascular-behavior
#9
L M Barin, R C S Barcelos, L T Vey, F M Pillusky, V M Palma, K Z Kantorski, M E Bürger, R M Maciel, C C Danesi
BACKGROUND: To evaluate for the first time in vivo the effects of methylene blue (MB) photosensitizer dissolved in ethanol in antimicrobial photodynamic therapy (aPDT) as adjuvant periodontal treatment, at plasmatic oxidative stress and vascular behavior in rat model. METHODS: Wistar rats were divided into negative control (NC, no periodontitis) and positive control (PC, with periodontitis, without any treatment). The other groups had periodontitis and were treated with scaling and root planing (SRP); SRP+aPDT+MB dissolved in water (aPDT I); SRP+aPDT+MB dissolved in ethanol (aPDT II)...
June 28, 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/28692500/effect-of-spreader-graft-on-nasal-functions-in-septorhinoplasty-surgery
#10
Marlen Mamanov, Ayşegül Batioglu-Karaaltin, Ender Inci, Zülküf Burak Erdur
OBJECTIVE: The authors aimed to investigate the effect of spreader grafts on nasal function in septorhinoplasty (SRP). METHODS: A prospective randomized double-blind study was conducted. Thirty patients who underwent SRP operation between October 2011 and January 2013 were divided into 2 equal groups randomly. Fifteen patients underwent SRP surgery without spreader graft technique (Group I) and 15 patients underwent SRP surgery with spreader grafts (Group II). Preoperative and postoperative evaluation included visual analog score (VAS) and acoustic rhinometry test...
July 7, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28688020/salvage-therapy-options-for-local-prostate-cancer-recurrence-after-primary-radiotherapy-a-literature-review
#11
REVIEW
Nicole M Golbari, Aaron E Katz
PURPOSE OF REVIEW: While recurrence after primary treatment of prostate cancer (PCa) is not uncommon, there is currently no consensus on the most appropriate management after radiation treatment failure. This article seeks to explore the currently utilized modalities for salvage treatment for radiorecurrent PCa. We focused our review on the oncologic outcomes and reported toxicity rates in the latest studies examining salvage radical prostatectomy (SRP), salvage cryotherapy (SCT), salvage high-intensity focused ultrasound (HIFU) and re-irradiation...
August 2017: Current Urology Reports
https://www.readbyqxmd.com/read/28678975/antibiotic-therapy-as-an-adjunct-to-scaling-and-root-planing-in-smokers-a-systematic-review-and-meta-analysis
#12
Naida Zanini Assem, Márcio Luiz Ferro Alves, Alessandra Barreto Lopes, Erivan Clementino Gualberto, Valdir Gouveia Garcia, Letícia Helena Theodoro
The aim of this study was to perform a systematic review and meta-analysis to examine the effect of systemic antibiotics in the periodontal treatment of smokers. The selection criteria were as follows: controlled randomized clinical trials; studies published in English; studies with smoker patients diagnosed with chronic periodontitis; patients without systemic diseases; studies that used systemic antibiotic therapy associated with periodontal treatment; studies that presented results for the test and control groups and assessments of clinical periodontal parameters, such as probing depth (PD), bleeding on probing (BOP), and clinical attachment level (CAL)...
July 3, 2017: Brazilian Oral Research
https://www.readbyqxmd.com/read/28678942/role-of-1-alendronate-gel-as-adjunct-to-mechanical-therapy-in-the-treatment-of-chronic-periodontitis-among-smokers
#13
Anuj Sharma, Achala Raman, Avani Raju Pradeep
Objective: Alendronate (ALN) inhibits osteoclastic bone resorption and triggers osteostimulative properties both in vivo and in vitro, as shown by increase in matrix formation. This study aimed to explore the efficacy of 1% ALN gel as local drug delivery (LDD) in adjunct to scaling and root planing (SRP) for the treatment of chronic periodontitis among smokers. Material and Methods: 75 intrabony defects were treated in 46 male smokers either with 1% ALN gel or placebo gel...
May 2017: Journal of Applied Oral Science: Revista FOB
https://www.readbyqxmd.com/read/28667678/effects-of-photodynamic-therapy-in-periodontal-treatment-a-randomized-controlled-clinical-trial
#14
M Segarra-Vidal, S Guerra-Ojeda, L S Vallés, A López-Roldán, M D Mauricio, M Aldasoro, F Alpiste-Illueca, J M Vila
AIM: To evaluate the effects of photodynamic therapy (PDT) in the nonsurgical treatment of chronic periodontitis. MATERIALS AND METHODS: A randomized, single-blind, controlled, parallel-group clinical trial was performed. Sixty patients were enrolled: 20 healthy controls and 40 patients with periodontitis. The 40 patients were randomized for scaling and root planing (SRP) or SRP+PDT. Periodontal (plaque index, probing depth, clinical recession, clinical attachment level, bleeding on probing, and gingival crevicular fluid volume, corresponding to 381 vs 428 critical sites), microbiological (Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Tannerella forsythia, Treponema denticola, Prevotella intermedia and Campylobacter rectus presence, 18 vs 19 samples) and biochemical (interleukin (IL)-1β, IL-6 and tumour necrosis factor (TNF)-α, receptor activator of nuclear factor-kappaB ligand (RANK-L) and osteoprotegerin (OPG) levels, 18 vs 19 samples) parameters were recorded...
July 1, 2017: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28662142/effects-of-the-probiotic-bifidobacterium-animalis-subsp-lactis-on-the-non-surgical-treatment-of-periodontitis-a-histomorphometric-microtomographic-and-immunohistochemical-study-in-rats
#15
Milla S T Ricoldi, Flávia A C Furlaneto, Luiz F F Oliveira, Gustavo C Teixeira, Jéssica P Pischiotini, André L G Moreira, Edilson Ervolino, Maricê N de Oliveira, Cristina S B Bogsan, Sérgio L Salvador, Michel R Messora
Lactobacillus probiotics have been investigated in periodontitis. However, the effects of the genus Bifidobacterium on periodontitis are hardly known. This study evaluated the effects of the probiotic (PROB) Bifidobacterium animalis subsp. lactis (B. lactis) HN019 as an adjunct to scaling and root planing (SRP) in rats with experimental periodontitis (EP). At baseline, 32 rats were assigned to 4 groups: C (control), PROB, EP-SRP and EP-SRP-PROB. In groups EP-SRP and EP-SRP-PROB, the mandibular first molars of the animals received a ligature...
2017: PloS One
https://www.readbyqxmd.com/read/28652898/effects-of-root-debridement-with-hand-curettes-and-er-yag-laser-on-chemical-properties-and-ultrastructure-of-periodontally-diseased-root-surfaces-using-spectroscopy-and-scanning-electron-microscopy
#16
Reza Amid, Gholam Ali Gholami, Masoud Mojahedi, Maryam Aghalou, Mohsen Gholami, Mahdieh Mirakhori
Introduction: The efficacy of erbium-doped yttrium aluminum garnet (Er:YAG) laser for root debridement in comparison with curettes has been the subject of many recent investigations. Considering the possibility of chemical and ultra-structural changes in root surfaces following laser irradiation, this study sought to assess the effects of scaling and root planing (SRP) with curettes and Er:YAG laser on chemical properties and ultrastructure of root surfaces using spectroscopy and scanning electron microscopy (SEM)...
2017: Journal of Lasers in Medical Sciences
https://www.readbyqxmd.com/read/28649298/neuroimaging-the-traumatized-self-fmri-reveals-altered-response-in-cortical-midline-structures-and-occipital-cortex-during-visual-and-verbal-self-and-other-referential-processing-in-women-with-ptsd
#17
Paul Frewen, Elizabeth Thornley, Daniela Rabellino, Ruth Lanius
Background: Changes to the diagnostic criteria for PTSD in DSM-5 reflect an increased emphasis on negative cognition referring to self and other, including self-blame, and related pervasive negative affective states including for self-conscious emotions such as guilt and shame. Objective: Investigate the neural correlates of valenced self-referential processing (SRP) and other-referential processing (ORP) in persons with PTSD. Method: We compared response to the Visual-Verbal Self-Other Referential Processing Task in an fMRI study of women with (n = 20) versus without (n = 24) PTSD primarily relating to childhood and interpersonal trauma histories using statistical parametric mapping and group independent component analysis...
2017: European Journal of Psychotraumatology
https://www.readbyqxmd.com/read/28648640/pulmonary-delivery-of-synergistic-combination-of-fluoroquinolone-antibiotic-complemented-with-proteolytic-enzyme-a-novel-antimicrobial-and-antibiofilm-strategy
#18
Purnima V Gupta, Abhijit M Nirwane, Tejashree Bellubi, Mangal S Nagarsenker
Bacterial resistance remains a major hindrance in treatment with antimicrobial agents. Therefore, we assessed the improved antimicrobial and antibiofilm activity of Levofloxacin (LFX) and Serratiopeptidase (SRP) combinations in in vitro microbiological studies. Further, pharmacodynamic and pharmacokinetic studies of liposomal LFX in combination with SRP (LFX liposome-SRP) were performed in S. aureus infected rats. LFX at sub-MIC with SRP eradicated >90% of the preformed biofilm. The entrapment efficiency of LFX in liposome was >80% and the co-spray dried product had MMAD <5 μ...
June 23, 2017: Nanomedicine: Nanotechnology, Biology, and Medicine
https://www.readbyqxmd.com/read/28647876/characteristics-and-effects-of-dissolved-organic-phosphorus-from-different-sources-on-the-water-quality-of-erhai-lake-in-southwest-china
#19
Ningning Ji, Shengrui Wang, Li Zhang, Zhaokui Ni
To establish the influence of dissolved organic phosphorus (DOP) from different sources on the water quality of Erhai Lake in August 2014, enzymatic hydrolysis technology was used to characterize enzymatically hydrolyzable phosphorus (EHP). The results indicate that the DOP represents a significant source of the bioavailable P in the lake water and its different sources of Erhai Lake, and the bioavailability of the P pool may be underestimated by up to 55% if DOP is ignored and only the soluble-reactive phosphorus (SRP) is considered...
June 24, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28637585/effects-of-periodontal-endoscopy-on-the-treatment-of-periodontitis-a-systematic-review-and-meta-analysis
#20
REVIEW
Yunchun Kuang, Bo Hu, Jin Chen, Ge Feng, Jinlin Song
BACKGROUND: For this systematic review, the authors evaluated and synthesized the available scientific evidence related to the effects of periodontal endoscopy on the treatment of periodontitis. METHODS: The authors searched PubMed, Embase, Cochrane Library, Chinese Scientific Journals database, China National Knowledge Infrastructure, and Chinese Medicine Premier's Wanfang database for articles about periodontal endoscopy that were published through January 2017...
June 18, 2017: Journal of the American Dental Association
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