keyword
https://read.qxmd.com/read/38420363/potential-mechanism-of-tea-for-treating-osteoporosis-osteoarthritis-and-rheumatoid-arthritis
#21
REVIEW
Xinyu Xie, Jiehui Fu, Weiying Gou, Yifei Qin, Dingzhen Wang, Zuer Huang, Lili Wang, Xihai Li
Osteoporosis (OP), osteoarthritis (OA), and rheumatoid arthritis (RA) are common bone and joint diseases with a high incidence and long duration. Thus, these conditions can affect the lives of middle-aged and elderly people. Tea drinking is a traditional lifestyle in China, and the long-term intake of tea and its active ingredients is beneficial to human health. However, the mechanisms of action of tea and its active ingredients against OP, OA, and RA are not completely elucidated. This study aimed to assess the therapeutic role and related mechanisms of tea and its active ingredients in OP, OA, and RA...
2024: Frontiers in Medicine
https://read.qxmd.com/read/38407390/yellow-leaf-green-tea-modulates-ampk-acc-srebp1c-signaling-pathway-and-gut-microbiota-in-high-fat-diet-induced-mice-to-alleviate-obesity
#22
JOURNAL ARTICLE
Baoming Tian, Yizhu Pan, Xue Zhou, Yuezhi Jiang, Xiangchun Zhang, Xudong Luo, Kai Yang
BACKGROUND: Yellow leaf green tea (YLGT) is a new variety of Camellia sinensis (L.) O. Ktze, which has yellow leaves and the unique qualities of 'three green through three yellow'. This study aimed to investigate the anti-obesity effect of YLGT in mice fed a high-fat diet (HFD) and to explore the potential mechanisms by regulating the AMPK/ACC/SREBP1c signaling pathways and gut microbiota. RESULTS: The results showed that YLGT aqueous extract reduced body weight, hepatic inflammation, fat accumulation and hyperlipidemia in HFD-induced C57BL/6J mice, and accelerated energy metabolism, reduced fat synthesis, and suppressed obesity by activating the AMPK/CPT-1α signaling pathway and inhibiting the FAS/ACC/SREBP-1c signaling pathway...
February 26, 2024: Journal of the Science of Food and Agriculture
https://read.qxmd.com/read/38399496/a-preliminary-report-regarding-the-morphological-changes-of-nano-enabled-pharmaceutical-formulation-on-human-lung-carcinoma-monolayer-and-3d-bronchial-microtissue
#23
JOURNAL ARTICLE
Cătălin Prodan-Bărbulescu, Claudia-Geanina Watz, Elena-Alina Moacă, Alexandra-Corina Faur, Cristina-Adriana Dehelean, Flaviu Ionut Faur, Laura Octavia Grigoriţă, Anca Laura Maghiari, Paul Tuţac, Ciprian Duţă, Sorin Bolintineanu, Laura Andreea Ghenciu
Background and Objectives : Nowadays, the development of enabled pharmaceutical nanoparticles of solid lipid type is continuously growing, because they have the potential to be used for targeted drug release leading to an increased effect of chemotherapy, being used in lung cancer nano-diagnosis and nano-therapy. The current study reports the preliminary results obtained regarding the biological effect of a new nano-enabled pharmaceutical formulation in terms of its cytotoxic and biosafety profile. Materials and Methods : The pharmaceutical formulations consist of solid lipid nanoparticles (SLN) obtained via the emulsification-diffusion method by loading green iron oxide nanoparticles (green-IONPs) with a pentacyclic triterpene (oleanolic acid-OA)...
January 25, 2024: Medicina
https://read.qxmd.com/read/38397595/preparation-and-physicochemical-analysis-of-camellia-sinensis-cv-ziyan-anthocyanin-microcapsules
#24
JOURNAL ARTICLE
Ruixin Xue, Xiang Yuan, Hong Jiang, Hong Huang, Xiaocong Luo, Pinwu Li
The new tea cultivar Ziyan has a high content of anthocyanin and ester catechins in the raw material, but the conventional processing and application methods are limited. To explore its application potential, the freeze-drying method was used to prepare microcapsules with an embedding time of 30 min, solid content of 30%, and core to wall ratio of 1:10 (g/g). The anthocyanin recovery was 95.94 ± 0.50%, and the encapsulation efficiency was 96.15 ± 0.11%. The stability of microcapsules and composite wall materials was evaluated in the simulation system...
February 19, 2024: Foods (Basel, Switzerland)
https://read.qxmd.com/read/38397522/recent-advances-regarding-polyphenol-oxidase-in-camellia-sinensis-extraction-purification-characterization-and-application
#25
REVIEW
Chun Zou, Xin Zhang, Yongquan Xu, Junfeng Yin
Polyphenol oxidase (PPO) is an important metalloenzyme in the tea plant ( Camellia sinensis ). However, there has recently been a lack of comprehensive reviews on Camellia sinensis PPO. In this study, the methods for extracting PPO from Camellia sinensis , including acetone extraction, buffer extraction, and surfactant extraction, are compared in detail. The main purification methods for Camellia sinensis PPO, such as ammonium sulfate precipitation, three-phase partitioning, dialysis, ultrafiltration, ion exchange chromatography, gel filtration chromatography, and affinity chromatography, are summarized...
February 9, 2024: Foods (Basel, Switzerland)
https://read.qxmd.com/read/38393428/regulation-of-blue-infertile-flower-pigmentation-by-wd40-transcription-factor-hmwdr68-in-hydrangea-macrophylla-forever-summer
#26
JOURNAL ARTICLE
Jingyi Gong, Yu Wang, Chao Xue, Linshi Wu, Song Sheng, Meng Wang, Jiqing Peng, Shoujin Cao
BACKGROUND: WD40 transcription factors are crucial in plant growth and developmental, significantly impacting plant growth regulation. This study investigates the WD40 transcription factor HmWDR68's role in developing the distinctive blue infertile flower colors in Hydrangea macrophylla 'Forever Summer'. METHODS AND RESULTS: The HmWDR68 gene was isolated by PCR, revealing an open reading frame of 1026 base pairs, which encodes 341 amino acids. Characterized by four WD40 motifs, HmWDR68 is a member of the WD40 family...
February 23, 2024: Molecular Biology Reports
https://read.qxmd.com/read/38393243/using-quechers-and-hplc-method-to-monitor-the-background-concentration-of-polycyclic-aromatic-hydrocarbons-in-commercial-black-tea-leaves-and-infusions-in-taiwan
#27
JOURNAL ARTICLE
Drewyan Minelly Harrison, Wei-Chung Chang, Hsin-Tang Lin
Tea is an integral part of Taiwanese culture and is a popular drink as it contains many beneficial compounds. However, during the processing of tea, polycyclic aromatic hydrocarbons (PAHs) may form. This study investigated the concentrations of PAH4 in different black tea leaves and tea infusions based on the origin of the tea. The samples were extracted using QuEChERS, while the content of PAH4 was analyzed by high performance liquid chromatography coupled to a fluorescence detector (HPLC-FLD). The content of PAH4 in the tea leaves ranged from 2...
February 14, 2024: Toxics
https://read.qxmd.com/read/38393229/dietary-exposure-and-health-risk-assessment-of-polycyclic-aromatic-hydrocarbons-in-black-tea-consumed-in-taiwan
#28
JOURNAL ARTICLE
Drewyan Minelly Harrison, Wei-Chung Chang, Hsin-Tang Lin
Polycyclic aromatic hydrocarbons (PAHs) are organic compounds found in many foods and drinks, and there have been some concerns over these compounds due to their carcinogenic nature. This study evaluated the concentrations of PAH4 (BaP, BaA, BbF, and CHR) in different black tea infusions and drinks based on the origin of the tea. The release of PAH4 from tea leaves to tea infusions was significantly low, with the highest transfer being 25.81%. The mean concentrations of BaP and PAH4 in tea infusions were used to conduct a risk assessment for the Taiwanese population, which showed that the 19-65 age group had the highest estimated intake of PAH4 and BaP among all age groups...
February 7, 2024: Toxics
https://read.qxmd.com/read/38392813/a-phylogenetic-and-taxonomic-revision-of-discula-theae-sinensis-the-causal-agents-of-anthracnose-on-camellia-sinensis
#29
JOURNAL ARTICLE
Meijun Guo, Shiyi Zhao, Yue Gao, Xiaoye Shen, Chenglin Hou
Tea ( Camellia sinensis (L.) Kuntze) is one of the most important economic plants in China, and has many benefits for human health. Anthracnose is one of the most serious diseases of tea in China, and control of the fungus is important since most Chinese cultivars are susceptible to it. The agent of tea anthracnose was initially described as Gloeosporium theae-sinensis I. Miyake in Japan, which was later transferred to Discula , but this taxonomic position remains problematic. To shed light on these taxonomic and phylogenetic issues, the tea anthracnose pathogens were re-studied...
February 9, 2024: Journal of Fungi (Basel, Switzerland)
https://read.qxmd.com/read/38392187/comparative-phylogenetic-analysis-of-ancient-korean-tea-hadong-cheon-nyeon-cha-camellia-sinensis-var-sinensis-using-complete-chloroplast-genome-sequences
#30
JOURNAL ARTICLE
Doobo Shim, Seung Ho Jeon, Jong Cheol Kim, Dong-Kyung Yoon
Wild teas are valuable genetic resources for studying evolution and breeding. Here, we report the complete chloroplast genome of the ancient Korean tea 'Hadong Cheon-nyeon Cha' ( C. sinensis var. sinensis ), which is known as the oldest tea tree in Korea. This study determined seven Camellia sinensis var. sinenesis , including Hadong Cheon-nyeon Cha (HCNC) chloroplast genome sequences, using Illumina sequencing technology via de novo assembly. The chloroplast genome sizes ranged from 157,019 to 157,114 bp and were organized into quadripartite regions with the typical chloroplast genomes...
January 24, 2024: Current Issues in Molecular Biology
https://read.qxmd.com/read/38384681/combining-ion-mobility-spectrometry-and-chemometrics-for-detecting-synthetic-colorants-in-black-tea-a-reliable-and-fast-method
#31
JOURNAL ARTICLE
Mina Sobhaninia, Ahmad Mani-Varnosfaderani, Mohsen Barzegar, Mohammad Ali Sahari
Black tea ( Camellia sinensis ) is a widely consumed beverage and is subjected to adulteration. In this study, the combination of ion mobility spectrometry and machine learning techniques was employed to detect synthetic colorants in black tea. To accomplish our objective, six synthetic colorants (carmine, carmoisine, indigo carmine, brilliant blue, sunset yellow, and tartrazine) were added to pure tea at different concentrations. A qualitative model was built using partial least squares discriminant analysis (PLS-DA) for the collected data and exhibited 100% accuracy in identifying synthetic colorants in black tea...
March 30, 2024: Food chemistry: X
https://read.qxmd.com/read/38376143/mir828a-csmyb114-module-negatively-regulates-the-biosynthesis-of-theobromine-in-camellia-sinensis
#32
JOURNAL ARTICLE
Qifang Jin, Zhong Wang, Devinder Sandhu, Lan Chen, Chenyu Shao, Siyi Xie, Fanghuizi Shang, Shuai Wen, Ting Wu, Huiying Jin, Feiyi Huang, Guizhi Liu, Jinyu Hu, Qin Su, Mengdi Huang, Qian Zhu, Biao Zhou, Lihua Zhu, Lvwen Peng, Zhonghua Liu, Jianan Huang, Na Tian, Shuoqian Liu
Theobromine is an important quality component in tea plants ( Camellia sinensis ), which is produced from 7-methylxanthine by theobromine synthase ( CsTbS ), the key rate-limiting enzyme in theobromine biosynthetic pathway. Our transcriptomics and widely targeted metabolomics analyses suggested that CsMYB114 acted as a potential hub gene involved in the regulation of theobromine biosynthesis. The inhibition of CsMYB114 expression using antisense oligonucleotides (ASO) led to a 70.21% reduction of theobromine level in leaves of the tea plant, which verified the involvement of CsMYB114 in theobromine biosynthesis...
February 20, 2024: Journal of Agricultural and Food Chemistry
https://read.qxmd.com/read/38363398/ecological-risk-assessment-of-heavy-metals-in-tea-plantation-soil-around-tai-lake-region-in-suzhou-china
#33
JOURNAL ARTICLE
Xiaohan Xu, Jiahui Yang, Yang Zhang, Xueyan Sui, Zelong Gong, Shujing Liu, Xuan Chen, Xinghui Li, Yuhua Wang
Tea plant [Camellia sinensis (L.) O. Kuntze] is one of the important foliar cash crops in China, and its root system absorbs heavy metal (HM) elements enriched in the soil and transports them to the over ground part. In order to ensure the safety of the soil ecological environment and tea raw materials in the tea production area, the HM contents of soil and tea plant leaves in Suzhou tea plantations were detected, the relationship between HMs and soil physicochemical properties was analyzed, and the ecological risk of HMs in tea plantation soils was evaluated by using relevant detection techniques and evaluation models...
February 16, 2024: Stress Biol
https://read.qxmd.com/read/38359057/synthesis-of-silver-nanoparticles-using-camellia-sinensis-leaf-extract-promising-particles-for-the-treatment-of-cancer-and-diabetes
#34
JOURNAL ARTICLE
Md Eram Hosen, Md Ataur Rahman, Md Sojiur Rahman, Shopnil Akash, Md Khalekuzzaman, Abdulaziz Abdullah Alsahli, Mohammed Bourhia, Hiba-Allah Nafidi, Md Asadul Islam, Rashed Zaman
Both diabetes and cancer pose significant threats to public health. To overcome these challenges, nanobiotechnology offers innovative solutions for the treatment of these diseases. However, the synthesis of nanoparticles can be complex, costly and environmentally toxic. Therefore, in this study, we successfully synthesized Camellia sinensis silver nanoparticles (CS-AgNPs) biologically from methanolic leaf extract of C. sinensis and as confirmed by the visual appearance which exhibited strong absorption at 456 nm in UV-visible spectroscopy...
February 15, 2024: Chemistry & Biodiversity
https://read.qxmd.com/read/38357888/dynamic-dna-methylation-regulates-season-dependent-secondary-metabolism-in-the-new-shoots-of-tea-plants
#35
JOURNAL ARTICLE
Mengxue Han, Shijia Lin, Biying Zhu, Wei Tong, Enhua Xia, Yuanrong Wang, Tianyuan Yang, Shupei Zhang, Xiaochun Wan, Jianjun Liu, Qingfeng Niu, Jianhua Zhu, Shilai Bao, Zhaoliang Zhang
Plant secondary metabolites are critical quality-conferring compositions of plant-derived beverages, medicines, and industrial materials. The accumulations of secondary metabolites are highly variable among seasons; however, the underlying regulatory mechanism remains unclear, especially in epigenetic regulation. Here, we used tea plants to explore an important epigenetic mark DNA methylation (5mC)-mediated regulation of plant secondary metabolism in different seasons. Multiple omics analyses were performed on spring and summer new shoots...
February 15, 2024: Journal of Agricultural and Food Chemistry
https://read.qxmd.com/read/38350140/cloning-and-expression-analysis-of-key-enzyme-gene-cogpps-involved-in-iridoid-glycoside-synthesis-in-cornus-officinalis
#36
JOURNAL ARTICLE
Jiaxi Chen, Xinjie Tan, Guangyang Guo, Panpan Wang, Hongxiao Zhang, Shufang Lv, Huawei Xu, Dianyun Hou
Cornus iridoid glycosides (CIGs), including loganin and morroniside, are the main active components of Cornus officinalis . As one of the key enzymes in the biosynthesis of CIGs, geranyl pyrophosphate synthase (GPPS) catalyzes the formation of geranyl pyrophosphate, which is the direct precursor of CIGs. In this study, the C. officinalis geranyl pyrophosphate synthase (CoGPPS) sequence was cloned from C. officinalis and analyzed. The cDNA sequence of the CoGPPS gene was 915 bp (GenBank No. OR725699)...
February 13, 2024: DNA and Cell Biology
https://read.qxmd.com/read/38346524/anji-white-tea-relaxes-precontracted-arteries-represses-voltage-gated-ca-2-channels-and-voltage-gated-k-channels-in-the-arterial-smooth-muscle-cells-comparison-with-green-tea-main-component-epigallocatechin-gallate
#37
JOURNAL ARTICLE
Xiaojia Xu, Yingying Fan, Xiaomin Yang, Yu Liu, Yan Wang, Jiangtao Zhang, Xiaomin Hou, Yanying Fan, Mingsheng Zhang
ETHNOPHARMACOLOGICAL RELEVANCE: Tea (Camellia sinensis) is a favorite drink worldwide. Tea extracts and green tea main component (-)-epigallocatechin gallate (EGCG) are recommended for various vascular diseases. Anji white tea is a very popular green tea. Its vascular effect profile, the mechanisms, and the contribution of EGCG to its integrated effect need elucidation. AIM: To characterize the vasomotion effects of Anji white tea and EGCG, and to explore possible involvement of voltage-gated Ca2+ channels (VGCCs) and voltage-gated K+ (Kv) channels in their vasomotion effects...
February 10, 2024: Journal of Ethnopharmacology
https://read.qxmd.com/read/38340860/pollution-indices-of-selected-metals-in-tea-camellia-sinensis-l-growing-soils-of-the-upper-assam-region-divulges-a-non-trifling-menace-of-national-highway
#38
JOURNAL ARTICLE
Bidyot Bikash Gogoi, Md Yeasin, Ranjit Kumar Paul, Diganta Deka, Harisadhan Malakar, Jiban Saikia, Feroze Hasan Rahman, C S Maiti, Animesh Sarkar, Jyotirekha G Handique, Bappaditya Kanrar, A K Singh, Tanmoy Karak
The study investigated the influence of a National Highway (NH) traversing tea estates (TEs) on heavy metal (HM) contamination in the top soils of Upper Assam, India. The dispersion and accumulation of six HMs, viz. cadmium (Cd), copper (Cu), iron (Fe), manganese (Mn), nickel (Ni), and zinc (Zn), within tea-growing soils were assessed using diverse indices: contamination factor (CF), degree of contamination (DC), enrichment factor (EF), geo-accumulation index (Igeo ), modified degree of contamination (MDC), Nemerow pollution index (PINemerow ), pollution load index (PLI), potential ecological risk factor (Er i ), and potential ecological risk index (RI)...
February 8, 2024: Science of the Total Environment
https://read.qxmd.com/read/38338630/identification-of-key-genes-associated-with-1-2-6-tri-o-galloyl-%C3%AE-d-glucopyranose-accumulation-in-camellia-sinensis-based-on-transcriptome-sequencing
#39
JOURNAL ARTICLE
Yueqi Wang, Hanshuo Xun, Liubin Wang, Shirin Aktar, Yuping Lei, Rui Zhang, Liyuan Wang, Kang Wei
Hydrolyzed tannin 1,2,6-tri-O-galloyl-β-D-glucopyranose (1,2,6-TGGP) possesses significant medicinal properties. However, little is known about its underlying molecular mechanisms. In this study, the levels of 1,2,6-TGGP in tea materials from different cultivars and leaf positions were compared. Additionally, one leaf and one bud sample from six tea cultivars with significant variations in 1,2,6-TGGP levels were analyzed using transcriptome high-throughput sequencing to identify the genes that are responsible for 1,2,6-TGGP accumulation...
February 4, 2024: Foods (Basel, Switzerland)
https://read.qxmd.com/read/38337959/multi-omics-research-accelerates-the-clarification-of-the-formation-mechanism-and-the-influence-of-leaf-color-variation-in-tea-camellia-sinensis-plants
#40
REVIEW
Yan-Gen Fan, Ting-Ting Zhao, Qin-Zeng Xiang, Xiao-Yang Han, Shu-Sen Yang, Li-Xia Zhang, Li-Jun Ren
Tea is a popular beverage with characteristic functional and flavor qualities, known to be rich in bioactive metabolites such as tea polyphenols and theanine. Recently, tea varieties with variations in leaf color have been widely used in agriculture production due to their potential advantages in terms of tea quality. Numerous studies have used genome, transcriptome, metabolome, proteome, and lipidome methods to uncover the causes of leaf color variations and investigate their impacts on the accumulation of crucial bioactive metabolites in tea plants...
January 31, 2024: Plants (Basel, Switzerland)
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