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Camellia sinensis

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https://www.readbyqxmd.com/read/27908701/inhibitory-effects-of-l-theanine-on-airway-inflammation-in-ovalbumin-induced-allergic-asthma
#1
Yong Pil Hwang, Sun Woo Jin, Jae Ho Choi, Chul Yung Choi, Hyung Gyun Kim, Se Jong Kim, Yongan Kim, Kyung Jin Lee, Young Chul Chung, Hye Gwang Jeong
L-theanine, a water-soluble amino acid isolated from green tea (Camellia sinensis), has anti-inflammatory activity, antioxidative properties, and hepatoprotective effects. However, the anti-allergic effect of L-theanine and its underlying molecular mechanisms have not been elucidated. In this study, we investigated the protective effects of L-theanine on asthmatic responses, particularly airway inflammation and oxidative stress modulation in an ovalbumin (OVA)-induced murine model of asthma. Treatment with L-theanine dramatically attenuated the extensive trafficking of inflammatory cells into bronchoalveolar lavage fluid (BALF)...
November 28, 2016: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/27898032/the-antiproliferative-effect-of-chakasaponins-i-and-ii-floratheasaponin-a-and-epigallocatechin-3-o-gallate-isolated-from-camellia-sinensis-on-human-digestive-tract-carcinoma-cell-lines
#2
Niichiro Kitagawa, Toshio Morikawa, Chiaki Motai, Kiyofumi Ninomiya, Shuhei Okugawa, Ayaka Nishida, Masayuki Yoshikawa, Osamu Muraoka
Acylated oleanane-type triterpene saponins, namely chakasaponins I (1) and II (2), floratheasaponin A (3), and their analogs, together with catechins-including (-)-epigallocatechin 3-O-gallate (4), flavonoids, and caffeine-have been isolated as characteristic functional constituents from the extracts of "tea flower", the flower buds of Camellia sinensis (Theaceae), which have common components with that of the leaf part. These isolates exhibited antiproliferative activities against human digestive tract carcinoma HSC-2, HSC-4, MKN-45, and Caco-2 cells...
November 26, 2016: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/27897996/in-vitro-chemopreventive-properties-of-green-tea-rooibos-and-honeybush-extracts-in-skin-cells
#3
Tandeka U Magcwebeba, Pieter Swart, Sonja Swanevelder, Elizabeth Joubert, Wentzel C A Gelderblom
The chemopreventive properties of the herbal teas rooibos (Aspalathus linearis) and honeybush (Cyclopia spp.) have been demonstrated on mouse skin in vivo but the underlying mechanisms are not clear. The aim of the current study was to determine the anti-proliferative and pro-apoptotic activity of methanol and aqueous extracts of rooibos and two Cyclopia species in different skin cells, using green tea (Camellia sinensis) as a benchmark. Extracts were also characterised for their major individual polyphenols by high performance liquid chromatography and spectroscopically for the total polyphenol (TP) groups...
November 25, 2016: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/27883942/dye-degradation-by-green-heterogeneous-fenton-catalysts-prepared-in-presence-of-camellia-sinensis
#4
Samira S F Carvalho, Nakédia M F Carvalho
This work describes the synthesis and characterization of supported green iron catalysts, prepared with Camellia sinensis tea extract, and their application in heterogeneous Fenton degradation of pollutant dyes. The influence of the catalyst synthesis conditions in the iron and organic content were investigated by X-ray fluorescence and thermogravimetric analyses. Irregular, chain-like nanoparticles, in the size range of 20-100 nm, capped by polyphenolic natural compounds, were visualized by TEM micrographs...
November 21, 2016: Journal of Environmental Management
https://www.readbyqxmd.com/read/27872842/transcriptome-based-analysis-of-dof-family-transcription-factors-and-their-responses-to-abiotic-stress-in-tea-plant-camellia-sinensis
#5
Hui Li, Wei Huang, Zhi-Wei Liu, Yong-Xin Wang, Jing Zhuang
Tea plant (Camellia sinensis (L.) O. Kuntze) is affected by abiotic stress during its growth and development. DNA-binding with one finger (Dof) transcription factors (TFs) play important roles in abiotic stress tolerance of plants. In this study, a total of 29 putative Dof TFs were identified based on transcriptome of tea plant, and the conserved domains and common motifs of these CsDof TFs were predicted and analyzed. The 29 CsDof proteins were divided into 7 groups (A, B1, B2, C1, C2.1, C2.2, and D2), and the interaction networks of Dof proteins in C...
2016: International Journal of Genomics
https://www.readbyqxmd.com/read/27861949/absolute-quantification-of-micrornas-in-green-tea-camellia-sinensis-by-stem-loop-quantitative-real-time-pcr
#6
Ying-Hui Hou, Anburaj Jeyaraj, Xiao Zhang, Chao-Ling Wei
BACKGROUND: There are some studies to show that food-derived plant microRNAs (miRNAs) may be detected in mammals. The research evidence has being provoked a considerable debate whether plant-derived miRNAs exert the same regulatory functions as endogenous animal miRNAs. To test the hypothesis, the methods of highly sensitive absolute quantification miRNAs have been developed. However, absolute miRNA quantification of green tea has not yet been reported. In this study, it is the first to build an absolute quantification method to detect miRNAs level in green tea using stem-loop quantitative real-time PCR (qRT-PCR)...
November 12, 2016: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/27855934/variation-of-theanine-phenolic-and-methylxanthine-compounds-in-21-cultivars-of-camellia-sinensis-harvested-in-different-seasons
#7
Rui Fang, Sally P Redfern, Don Kirkup, Elaine A Porter, Geoffrey C Kite, Leon A Terry, Mark J Berry, Monique S J Simmonds
This is the first study to use chemometric methods to differentiate among 21 cultivars of Camellia sinensis from China and between leaves harvested at different times of the year using 30 compounds implicated in the taste and quality of tea. Unique patterns of catechin derivatives were observed among cultivars and across harvest seasons. C. sinensis var. pubilimba (You 510) differed from the cultivars of C. sinensis var. sinensis, with higher levels of theobromine, (+)-catechin, gallocatechin, gallocatechin gallate and theasinensin B, and lower levels of (-)-epicatechin, (-)-epigallocatechin (EGC) and (-)-epigallocatechin gallate (EGCG), respectively...
April 1, 2017: Food Chemistry
https://www.readbyqxmd.com/read/27855193/transcriptome-wide-identification-and-expression-analysis-of-the-nac-gene-family-in-tea-plant-camellia-sinensis-l-o-kuntze
#8
Yong-Xin Wang, Zhi-Wei Liu, Zhi-Jun Wu, Hui Li, Jing Zhuang
In plants, the NAC (NAM-ATAF1/2-CUC) family of proteins constitutes several transcription factors and plays vital roles in diverse biological processes, such as growth, development, and adaption to adverse factors. Tea, as a non-alcoholic drink, is known for its bioactive ingredients and health efficacy. Currently, knowledge about NAC gene family in tea plant remains very limited. In this study, a total of 45 CsNAC genes encoding NAC proteins including three membrane-bound members were identified in tea plant through transcriptome analysis...
2016: PloS One
https://www.readbyqxmd.com/read/27853259/comparative-transcriptome-analysis-of-chinary-assamica-and-cambod-tea-camellia-sinensis-types-during-development-and-seasonal-variation-using-rna-seq-technology
#9
Ajay Kumar, Vandna Chawla, Eshita Sharma, Pallavi Mahajan, Ravi Shankar, Sudesh Kumar Yadav
Tea quality and yield is influenced by various factors including developmental tissue, seasonal variation and cultivar type. Here, the molecular basis of these factors was investigated in three tea cultivars namely, Him Sphurti (H), TV23 (T), and UPASI-9 (U) using RNA-seq. Seasonal variation in these cultivars was studied during active (A), mid-dormant (MD), dormant (D) and mid-active (MA) stages in two developmental tissues viz. young and old leaf. Development appears to affect gene expression more than the seasonal variation and cultivar types...
November 17, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27846826/natural-product-htp-screening-for-antibacterial-e-coli-0157-h7-and-anti-inflammatory-agents-in-lps-from-e-coli-o111-b4-activated-macrophages-and-microglial-cells-focus-on-sepsis
#10
Elizabeth A Mazzio, Nan Li, David Bauer, Patricia Mendonca, Equar Taka, Mohammed Darb, Leeshawn Thomas, Henry Williams, Karam F A Soliman
BACKGROUND: Acute systemic inflammatory response syndrome arising from infection can lead to multiple organ failure and death, with greater susceptibility occurring in immunocompromised individuals. Moreover, sub-acute chronic inflammation is a contributor to the pathology of diverse degenerative diseases (Parkinson's disease, Alzheimer's disease and arthritis). Given the known limitations in Western medicine to treat a broad range of inflammatory related illness as well as the emergence of antibiotic resistance, there is a renewed interest in complementary and alternative medicines (CAMs) to achieve these means...
November 15, 2016: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/27826184/design-development-and-characterization-of-lipid-nanocarriers-based-epigallocatechin-gallate-delivery-system-for-preventive-and-therapeutic-supplementation
#11
Iúri Frias, Ana Rute Neves, Marina Pinheiro, Salette Reis
Green tea is manufactured from the leaves of Camellia sinensis and has been shown to possess, among other properties, anticancer, antiobesity, antiatherosclerotic, antidiabetic, antibacterial, and antiviral effects. The beneficial effects of green tea are related to the activities of (-)-epigallocatechin gallate (EGCG). This catechin is very unstable, undergoing degradation and epimerization, which is responsible for the loss of its health benefits. Encapsulation in nanoparticles (NPs) is an effective method to protect EGCG from adverse environmental conditions...
2016: Drug Design, Development and Therapy
https://www.readbyqxmd.com/read/27809221/tea-polysaccharides-and-their-bioactivities
#12
REVIEW
Ling-Ling Du, Qiu-Yue Fu, Li-Ping Xiang, Xin-Qiang Zheng, Jian-Liang Lu, Jian-Hui Ye, Qing-Sheng Li, Curt Anthony Polito, Yue-Rong Liang
Tea (Camellia sinensis) is a beverage beneficial to health and is also a source for extracting bioactive components such as theanine, tea polyphenols (TPP) and tea polysaccharides (TPS). TPS is a group of heteropolysaccharides bound with proteins. There is evidence showing that TPS not only improves immunity but also has various bioactivities, such as antioxidant, antitumor, antihyperglycemia, and anti-inflammation. However, inconsistent results concerning chemical composition and bioactivity of TPS have been published in recent years...
October 30, 2016: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/27808374/expression-profile-analysis-of-ascorbic-acid-related-genes-in-response-to-temperature-stress-in-the-tea-plant-camellia-sinensis-l-o-kuntze
#13
H Li, W Huang, G L Wang, Z J Wu, J Zhuang
Ascorbic acid (AsA), also known as ascorbate or vitamin C, is a natural organic compound in green plants that has antioxidant properties, and is an essential nutrient for humans. The tea plant, Camellia sinensis (L.) O. Kuntze, is an important global economic crop. Here, the expression profiles of genes related to AsA biosynthesis and recycling were analyzed in tea plants in response to temperature stress. Eighteen genes involved in AsA biosynthesis and recycling pathways were identified based on the transcriptome database...
October 5, 2016: Genetics and Molecular Research: GMR
https://www.readbyqxmd.com/read/27807684/inhibition-of-murine-norovirus-and-feline-calicivirus-by-edible-herbal-extracts
#14
Dong Joo Seo, Changsun Choi
Human noroviruses (HuNoVs) cause foodborne and waterborne viral gastroenteritis worldwide. Because HuNoV culture systems have not been developed thus far, no available medicines or vaccines preventing infection with HuNoVs exist. Some herbal extracts were considered as phytomedicines because of their bioactive components. In this study, the inhibitory effects of 29 edible herbal extracts against the norovirus surrogates murine norovirus (MNV) and feline calicivirus (FCV) were examined. FCV was significantly inhibited to 86...
November 2, 2016: Food and Environmental Virology
https://www.readbyqxmd.com/read/27782129/diverse-colletotrichum-species-cause-anthracnose-of-tea-plants-camellia-sinensis-l-o-kuntze-in-china
#15
Yu-Chun Wang, Xin-Yuan Hao, Lu Wang, Bin Xiao, Xin-Chao Wang, Ya-Jun Yang
Anthracnose caused by Colletotrichum is one of the most severe diseases that can afflict Camellia sinensis. However, research on the diversity and geographical distribution of Colletotrichum in China remain limited. In this study, 106 Colletotrichum isolates were collected from diseased leaves of Ca. sinensis cultivated in the 15 main tea production provinces in China. Multi-locus phylogenetic analysis coupled with morphological identification showed that the collected isolates belonged to 11 species, including 6 known species (C...
October 26, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27774417/green-tea-catechin-inhibits-the-activity-and-neutrophil-release-of%C3%A2-matrix-metalloproteinase-9
#16
Wan K Kim-Park, Eman S Allam, Jadesada Palasuk, Michael Kowolik, Kichuel K Park, L Jack Windsor
Green tea (Camellia sinensis; lǜ chá) extracts have been shown to possess anti-oxidant and anti-inflammatory effects in various cell types. Green tea extract (GTX) has been shown to significantly inhibit the activity of collagenase-3 (matrix metalloproteinase-13 (MMP-13)) in vitro. MMPs, such as MMP-9, are known to be involved in many inflammatory diseases including periodontal disease. GTX and a major catechin, epigallocatechin-gallate (EGCG), were examined for their ability to inhibit purified MMP-9 activity and its release from stimulated neutrophils...
October 2016: Journal of Traditional and Complementary Medicine
https://www.readbyqxmd.com/read/27756641/interactions-between-%C3%AE-amylase-and-an-acidic-branched-polysaccharide-from-green-tea
#17
Shuyun Wu, Minghua Lai, Jiahao Luo, Jingwen Pan, Li-Ming Zhang, Liqun Yang
To understand the mechanism responsible for the α-amylase inhibitory activity of tea polysaccharides, the interaction between α-amylase and an acidic branched tea polysaccharide (TPSA) was investigated using fluorescence spectroscopy and resonance light scattering analysis. TPSA, exhibiting inhibitory activity towards α-amylase (the maximum inhibition percentage of 65%), was isolated from green tea (Camellia sinensis) and characterized by nuclear magnetic resonance spectroscopy, Fourier transform infrared spectroscopy, ultraviolet-visible spectroscopy, and gas chromatography...
October 15, 2016: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/27756219/gene-expression-profile-indicates-involvement-of-no-in-camellia-sinensis-pollen-tube-growth-at-low-temperature
#18
Junting Pan, Weidong Wang, Dongqin Li, Zaifa Shu, Xiaoli Ye, Pinpin Chang, Yuhua Wang
BACKGROUND: Nitric oxide (NO) functions as a critical signaling molecule in the low-temperature stress responses in plants, including polarized pollen tube growth in Camellia sinensis. Despite this, the potential mechanisms underlying the participation of NO in pollen tube responses to low temperature remain unclear. Here, we investigate alterations to gene expression in C. sinensis pollen tubes exposed to low-temperature stress and NO using RNA-Seq technology, in order to find the potential candidate genes related to the regulation of pollen tube elongation by NO under low-temperature stress...
October 18, 2016: BMC Genomics
https://www.readbyqxmd.com/read/27747873/antioxidants-from-black-and-green-tea-from-dietary-modulation-of-oxidative-stress-to-pharmacological-mechanisms
#19
REVIEW
Ilaria Peluso, Mauro Serafini
The consumption of tea (Camellia sinensis) has been correlated with a low incidence of chronic pathologies, such as cardiovascular disease and cancer, in which oxidative stress plays a critical role. Tea catechins and theaflavins are, respectively, the bioactive phytochemicals responsible for the antioxidant activity of green tea (GT) and black tea (BT). In addition to their redox properties, tea catechins and theaflavins could have also pharmacological activities, such as the ability to lower glucose, lipid and uric acid (UA) levels...
October 16, 2016: British Journal of Pharmacology
https://www.readbyqxmd.com/read/27706097/anti-inflammatory-effects-of-aspalathus-linearis-and-cyclopia-spp-extracts-in-a-uvb-keratinocyte-hacat-model-utilising-interleukin-1%C3%AE-accumulation-as-biomarker
#20
Tandeka Magcwebeba, Pieter Swart, Sonja Swanevelder, Elizabeth Joubert, Wentzel Gelderblom
Ultraviolet B (UVB) radiation is one of the major predisposing risk factors of skin cancer. The anticancer and photoprotective effects of unoxidized rooibos (Aspalathus linearis) and honeybush (Cyclopia) herbal teas, containing high levels of dihydrochalones and xanthones, respectively, have been demonstrated in skin cancer models in vivo. In the current study, the anti-inflammatory effects of methanol and aqueous extracts of these herbal teas were investigated in a UVB/HaCaT keratinocyte model with intracellular interleukin-1α (icIL-1α) accumulation as a biomarker...
October 2, 2016: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
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