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https://www.readbyqxmd.com/read/27885300/rebooting-the-franchise-the-2015-international-symposium-on-gpc-sec-and-related-techniques
#1
André M Striegel
No abstract text is available yet for this article.
August 2016: Chromatographia
https://www.readbyqxmd.com/read/27856857/japan-reboots-x-ray-probe-and-mission-management
#2
Dennis Normile
No abstract text is available yet for this article.
November 18, 2016: Science
https://www.readbyqxmd.com/read/27560266/off-the-cuff-rebooting-blood-pressure-treatment
#3
Steven R Steinhubl, Evan D Muse, Paddy M Barrett, Eric J Topol
No abstract text is available yet for this article.
August 20, 2016: Lancet
https://www.readbyqxmd.com/read/27558431/exploitation-of-interleukin-10-il-10-signaling-pathways-alternate-roles-of-viral-and-cellular-il-10-in-rhesus-cytomegalovirus-infection
#4
Meghan K Eberhardt, Ashlesha Deshpande, Joseph Fike, Rebecca Short, Kimberli A Schmidt, Shelley A Blozis, Mark R Walter, Peter A Barry
: There is accumulating evidence that the viral interleukin-10 (vIL-10) ortholog of both human and rhesus cytomegalovirus (HCMV and RhCMV, respectively) suppresses the functionality of cell types that are critical to contain virus dissemination and help shape long-term immunity during the earliest virus-host interactions. In particular, exposure of macrophages, peripheral blood mononuclear cells, monocyte-derived dendritic cells, and plasmacytoid dendritic cells to vIL-10 suppresses multiple effector functions including, notably, those that link innate and adaptive immune responses...
November 1, 2016: Journal of Virology
https://www.readbyqxmd.com/read/27476263/-a-sigh-increases-motivation-for-difficult-and-monotonous-tasks-the-effect-of-one-time-voluntary-brief-exhalation-on-relief-and-achievement-needs
#5
Kana Inoue, Yumi Yamamoto, Genji Sugamura
We tested possible intrapersonal effects of a sigh as a psychological "resetter/rebooter." Fifty-eight undergraduates were randomly assigned to a sigh or a normal exhalation (control) group. We asked participants on each task to model the experimenter demonstrating how to exhale air into a small plastic bag for breathing manipulation under the pretext that we were interested in the exhaled gas in stressful situations. Results revealed that the sigh group did not experience more relief (as shown by prolonged reaction time) after exposure to threat stimuli, but showed more persistence on a highly-difficult puzzle task (p = ...
June 2016: Shinrigaku Kenkyu: the Japanese Journal of Psychology
https://www.readbyqxmd.com/read/27293454/rannasangpei-is-a-therapeutic-agent-in-the-treatment-of-vascular-dementia
#6
Peng Wu, Yuandai Luo, Lifang Zhen, Xianda Hu, Ying Shang, Yinuo Liao, Huiyuan Xue, Fukai Huang, Wei Xiao
Rannasangpei (RSNP) is used as a therapeutic agent in the treatment of cardiovascular diseases, neurological disorders, and neurodegeneration in China; however, its potential use in the treatment of vascular dementia (VD) was unclear. In this study, our aim was to examine the neuroprotective effect of RSNP in a VD rat model, which was induced by permanent bilateral common carotid artery occlusion (2VO). Four-week administration with two doses of RSNP was investigated in our study. Severe cognitive deficit in the VD model, which was confirmed in Morris water maze (MWM) test, was significantly restored by the administration of RSNP...
2016: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/27176179/rebooting-the-microbiome
#7
Sean Munoz, Mabel Guzman-Rodriguez, Jun Sun, Yong-Guo Zhang, Curtis Noordhof, Shu-Mei He, Emma Allen-Vercoe, Erika C Claud, Elaine O Petrof
Using a murine Salmonella model of colitis, we recently reported that mice receiving a community of defined gut microbiota (MET-1) lost less weight, had reduced systemic inflammation and splenic S. typhimurium infection, and decreased neutrophil infiltration in the cecum, compared to vehicle controls. In addition, animals receiving MET-1 exhibited preserved tight junction protein expression (Zonula occludens-1, claudin-1), suggesting important effects on barrier function. In this addendum, we describe additional in vitro experiments examining effects of MET-1, as well as in vivo experiments demonstrating that MET-1 is protective in a DSS model of colitis after administration of antibiotics...
July 3, 2016: Gut Microbes
https://www.readbyqxmd.com/read/27151844/renewable-energy-a-reboot-for-wave-energy
#8
Erik Stokstad
No abstract text is available yet for this article.
May 6, 2016: Science
https://www.readbyqxmd.com/read/26989232/science-diplomacy-reboot-gitmo-for-u-s-cuba-research-diplomacy
#9
Joe Roman, James Kraska
No abstract text is available yet for this article.
March 18, 2016: Science
https://www.readbyqxmd.com/read/26961641/policy-reboot-the-debate-on-genetic-engineering
#10
Jennifer Kuzma
No abstract text is available yet for this article.
March 10, 2016: Nature
https://www.readbyqxmd.com/read/26957088/mammalian-target-of-rapamycin-complex-mtor-pathway-modulates-blood-testis-barrier-btb-function-through-f-actin-organization-and-gap-junction
#11
REVIEW
Nan Li, C Yan Cheng
mTOR (mammalian target of rapamycin) is one of the most important signaling molecules in mammalian cells which regulates an array of cellular events, ranging from cell metabolism to cell proliferation. Based on the association of mTOR with the core component proteins, such as Raptor or Rictor, mTOR can become the mTORC1 (mammalian target of rapamycin complex 1) or mTORC2, respectively. Studies have shown that during the epithelial cycle of spermatogenesis, mTORC1 promotes remodeling and restructuring of the blood-testis barrier (BTB) in vitro and in vivo, making the Sertoli cell tight junction (TJ)-permeability barrier "leaky"; whereas mTORC2 promotes BTB integrity, making the Sertoli cell TJ-barrier "tighter"...
September 2016: Histology and Histopathology
https://www.readbyqxmd.com/read/26952041/editorial-commentary-reprogramming-autologous-mesenchymal-stem-cells-to-regenerate-the-lost-myocardium-in-chronic-heart-failure-reboot-and-restore
#12
EDITORIAL
Matteo Vatta
No abstract text is available yet for this article.
July 2016: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/26941124/a-remote-controlled-generation-of-gold-polydopamine-core-shell-nanoparticles-via-physical-chemical-stimuli-of-polydopamine-gold-composites
#13
Yi Seul Lee, Ji Young Bae, Hye Young Koo, Young Boo Lee, Won San Choi
We present the synthesis of polydopamine particle-gold composites (PdopP-Au) and unique release of Au@Pdop core@shell nanoparticles (NPs) from the PdopP-Au upon external stimuli. The PdopP-Au was prepared by controlled synthesis of AuNPs on the Pdop particles. Upon near infrared (NIR) irradiation or NaBH4 treatment on the PdopP-Au, the synthesized AuNPs within the PdopPs could be burst-released as a form of Au@Pdop NPs. The PdopP-Au composite showed outstanding photothermal conversion ability under NIR irradiation due to the ultrahigh loading of the AuNPs within the PdopPs, leading to a remote-controlled explosion of the PdopP-Au and rapid formation of numerous Au@Pdop NPs...
2016: Scientific Reports
https://www.readbyqxmd.com/read/26762437/rebooted-kepler-spacecraft-hauls-in-the-planets
#14
Alexandra Witze
No abstract text is available yet for this article.
January 14, 2016: Nature
https://www.readbyqxmd.com/read/26699680/liver-regenerative-transplantation-regrow-and-reset
#15
REVIEW
A Collin de l'Hortet, K Takeishi, J Guzman-Lepe, K Handa, K Matsubara, K Fukumitsu, K Dorko, S C Presnell, H Yagi, A Soto-Gutierrez
Liver transplantation, either a partial liver from a living or deceased donor or a whole liver from a deceased donor, is the only curative therapy for severe end-stage liver disease. Only one-third of those on the liver transplant waiting list will be transplanted, and the demand for livers is projected to increase 23% in the next 20 years. Consequently, organ availability is an absolute constraint on the number of liver transplants that can be performed. Regenerative therapies aim to enhance liver tissue repair and regeneration by any means available (cell repopulation, tissue engineering, biomaterials, proteins, small molecules, and genes)...
June 2016: American Journal of Transplantation
https://www.readbyqxmd.com/read/26678449/connexin-43-reboots-meiosis-and-reseals-blood-testis-barrier-following-toxicant-mediated-aspermatogenesis-and-barrier-disruption
#16
Nan Li, Dolores D Mruk, Ka-Wai Mok, Michelle W M Li, Chris K C Wong, Will M Lee, Daishu Han, Bruno Silvestrini, C Yan Cheng
Earlier studies have shown that rats treated with an acute dose of 1-(2,4-dichlorobenzyl)-1H-indazole-3-carbohydrazide (adjudin, a male contraceptive under development) causes permanent infertility due to irreversible blood-testis barrier (BTB) disruption even though the population of undifferentiated spermatogonia remains similar to normal rat testes, because spermatogonia fail to differentiate into spermatocytes to enter meiosis. Since other studies have illustrated the significance of connexin 43 (Cx43)-based gap junction in maintaining the homeostasis of BTB in the rat testis and the phenotypes of Sertoli cell-conditional Cx43 knockout mice share many of the similarities of the adjudin-treated rats, we sought to examine if overexpression of Cx43 in these adjudin-treated rats would reseal the disrupted BTB and reinitiate spermatogenesis...
April 2016: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
https://www.readbyqxmd.com/read/26445588/pharmacare-2-0-aims-to-reboot-national-pharmacare-conversation
#17
(no author information available yet)
No abstract text is available yet for this article.
September 2015: Canadian Pharmacists Journal: CPJ, Revue des Pharmaciens du Canada: RPC
https://www.readbyqxmd.com/read/26442172/rebooting-the-genome-the-role-of-negative-feedback-in-horizontal-gene-transfer
#18
Raul Fernandez-Lopez, Fernando de la Cruz
Horizontal Gene Transfer (HGT) is one of the key mechanisms driving bacterial evolution. Conjugative plasmids are fundamental vehicles for HGT in bacteria, playing an essential role in the spread of antibiotic resistances. Although the classical view has stressed the instrumental role of these mobile genetic elements in the dissemination of antibiotic resistance genes, plasmids contain a rich physiology devoted to horizontal and vertical reproduction. This particular lifestyle imposes specific constrains and trade-offs on plasmid physiology, and plasmids have evolved dedicated circuits to balance the opposing demands of vertical and horizontal reproduction...
November 2014: Mobile Genetic Elements
https://www.readbyqxmd.com/read/26307887/mess-mangled-extremity-severity-score-25-years-on-time-for-a-reboot
#19
Kaj Johansen, Sigvard T Hansen
No abstract text is available yet for this article.
September 2015: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/26168199/rebooting-for-whom-portfolios-technology-and-personalized-intervention
#20
Varda Shoham, Thomas R Insel
We share Kazdin and Blase's (2011) sense of urgency about finding better ways to reduce the burden of mental illness. Although effective psychosocial treatments exist, they do not often reach the patients who need them most. Kazdin and Blase's portfolio approach aims to cast a wider net through increased use of technology, media, self-help, nonprofessional providers, and collaborations with other disciplines. It is unclear, however, whether reaching more people would suffice to reduce the burden of mental illness, much less offset the small effect sizes of simplified, scaled-down interventions such a portfolio approach would likely entail...
September 2011: Perspectives on Psychological Science: a Journal of the Association for Psychological Science
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