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Dahlia Tharwat, Marion Trousselard, Mélanie Balès, Anne-Laure Sutter-Dallay, Dominique Fromage, Elisabeth Spitz, Dominique Dallay, Thierry Harvey, Eric Welter, Frédéric Coatleven, Lydie Cherier, Frédérique Teissèdre, Jean-Luc Pouly, Frédéric Dutheil, Anaïs M Duffaud
INTRODUCTION: The prevalence of postnatal depression (PND) is significant: reaching up to 20% in the general population. In mechanistic terms, the risk of PND lies in an interaction between a maternal psychophysiological vulnerability and a chronic environmental context of stress. On the one hand, repetition of stressor during pregnancy mimics a chronic stress model that is relevant to the study of the allostatic load and the adaptive mechanisms. On the other hand, vulnerability factors reflect a psychological profile mirroring mindfulness functioning (psychological quality that involves bringing one's complete and non-judgemental attention to the present experience on a moment-to-moment basis)...
May 3, 2018: BMJ Open
Bencheikh Abdelhalim, Michael Fromager, Kamel Aït-Ameur
A novel technique to improve the focus depth of a Gaussian beam is presented in this paper. The improvement is based on two-step beam shaping using a cascade of binary phase diffractive optical elements (BPDOEs). The first BPDOE transforms the incident Gaussian beam into a high-order radial Laguerre-Gaussian beam (LGp0 ). Then the second BPDOE rectifies the obtained LGp0 beam and gives rise to a quasi-Gaussian one in the focal plane of a converging lens. This resulting quasi-Gaussian beam exhibits a lower divergence and larger focus depth compared to the pure Gaussian beam having the same beam waist...
March 10, 2018: Applied Optics
O Bouzid, S Haddadi, M Fromager, E Cagniot, K Ferria, A Forbes, K Ait-Ameur
Binary diffractive optics have been extensively studied to date as tools for arbitrary laser beam shaping and experimentally implemented with etched transparent optics and spatial light modulators. Here we demonstrate that a simple one-step binary optic is able to enhance the intensity of a focused beam, displaying some counterintuitive focusing anomalies. We explain these effects by considering the optical aberrations in binary diffractive optics and outline how this may be exploited for further improvements in refractive/diffractive combinations for super-resolution microscopy...
December 10, 2017: Applied Optics
Md Mehboob Alam, Killian Deur, Stefan Knecht, Emmanuel Fromager
The extrapolation technique of Savin [J. Chem. Phys. 140, 18A509 (2014)], which was initially applied to range-separated ground-state-density-functional Hamiltonians, is adapted in this work to ghost-interaction-corrected (GIC) range-separated ensemble density-functional theory (eDFT) for excited states. While standard extrapolations rely on energies that decay as μ-2 in the large range-separation-parameter μ limit, we show analytically that (approximate) range-separated GIC ensemble energies converge more rapidly (as μ-3 ) towards their pure wavefunction theory values (μ → +∞ limit), thus requiring a different extrapolation correction...
November 28, 2017: Journal of Chemical Physics
M Brunel, G Demange, M Fromager, M Talbi, H Zapolsky, R Patte, K Aït Ameur, J Jacquot-Kielar, S Coetmellec, G Gréhan, B Quevreux
Airborne characterization of ice crystals has important applications. The extreme difficulty of realizing in situ tests requires the development of a complete instrumentation in the laboratory. Such an installation should enable design, development, test, and calibration of instruments in conditions as close as possible to real ones. We present a set of numerical and experimental tools that have been developed to realize ice crystal sensors based on interferometric particle imaging. The set of tools covers the development of complementary simulators for crystal growth and interferometric particle imaging predictions, experimental generation of "programmable" ice crystals, and instrumentation of a freezing column where different techniques as in-focus imaging, out-of-focus imaging, and digital in-line holography can be combined simultaneously for test and calibration...
August 2017: Review of Scientific Instruments
Alexia Papageorgiou, Yoon K Loke, Michelle Fromage
BACKGROUND: Research evidence suggests that both mental health professionals and people with severe mental health illness such as schizophrenia or schizoaffective disorder find it difficult to communicate with each other effectively about symptoms, treatments and their side effects so that they reach a shared understanding about diagnosis, prognosis and treatment. Effective use of communication skills in mental health interactions could be associated with increased patient satisfaction and adherence to treatment...
June 13, 2017: Cochrane Database of Systematic Reviews
Pascale Lefevre, Alexandre Quignette, Pascal Gillet, Thomas Despreaux, Alexis Descatha
No abstract text is available yet for this article.
June 2017: Journal of Occupational and Environmental Medicine
M Fromager, K Aït Ameur, M Brunel
The 2D autocorrelation of the projection of an irregular rough particle can be estimated using the analysis of its interferometric out-of-focus image. We report the development of an experimental setup that creates speckle-like patterns generated by "programmable" rough particles of desired-shape. It should become an important tool for the development of new setups, configurations, and algorithms in interferometric particle imaging.
April 20, 2017: Applied Optics
Sergi Vela, Martin Verot, Emmanuel Fromager, Vincent Robert
The present paper reports the application of a computational framework, based on the quantum master equation, the Fermi's golden Rule, and conventional wavefunction-based methods, to describe electron transport through a spin crossover molecular junction (Fe(bapbpy) (NCS)2, 1, bapbpy = N-(6-(6-(Pyridin-2-ylamino)pyridin-2-yl)pyridin-2-yl)-pyridin-2-amine). This scheme is an alternative to the standard approaches based on the relative position and nature of the frontier orbitals, as it evaluates the junction's Green's function by means of accurate state energies and wavefunctions...
February 14, 2017: Journal of Chemical Physics
B Fromage, M Hatti
UNLABELLED: In palliative care, people with advanced or terminal phase cancer represent a significant proportion of patients. Persuaded that the pain and suffering they experience will never disappear from their daily life, patients are exposed to successive fracture triggered by psychosocial/physical factors. Furthermore, the difficulty in palliative care is that the pain is also a subjective phenomenon. However, the only information available to indicate pain remains the quantitative assessment of the patient or the observation of his/her behaviour...
December 2015: L'Encéphale
A Taupin, D Labbé, E Babin, G Fromager
INTRODUCTION: Recovering a certain degree of mimicry after sacrifice of the facial nerve is a clinically recognized finding. The authors report a case of hemifacial reanimation suggesting a phenomenon of neurotization from muscle-to-nerve. CLINICAL CASE: A woman benefited from a parotidectomy with sacrifice of the left facial nerve indicated for recurrent tumor in the gland. The distal branches of the facial nerve, isolated at the time of resection, were buried in the masseter muscle underneath...
December 2016: Annales de Chirurgie Plastique et Esthétique
G La Ruche, Y Le Strat, M Fromage, B Berçot, A Goubard, B de Barbeyrac, P Sednaoui, E Cambau, F Lot
Surveillance of sexually transmitted diseases in France is based on voluntary networks of laboratories and clinicians. Despite the importance of incidence data in improving knowledge about the national context and in international comparisons, such data were not previously available. During nationwide quality control of laboratories, mandatory for all laboratories, we conducted a survey in June 2013 to estimate the incidence rates of gonococcal and chlamydial infections for 2012 and to estimate the proportion of diagnoses performed (coverage) by the country's two laboratory-based sentinel networks for these diseases...
2015: Euro Surveillance: Bulletin Européen sur les Maladies Transmissibles, European Communicable Disease Bulletin
Julie Pilliod, Sébastien Moutton, Julie Lavie, Elise Maurat, Christophe Hubert, Nadège Bellance, Mathieu Anheim, Sylvie Forlani, Fanny Mochel, Karine N'Guyen, Christel Thauvin-Robinet, Christophe Verny, Dan Milea, Gaëtan Lesca, Michel Koenig, Diana Rodriguez, Nada Houcinat, Julien Van-Gils, Christelle M Durand, Agnès Guichet, Magalie Barth, Dominique Bonneau, Philippe Convers, Elisabeth Maillart, Lucie Guyant-Marechal, Didier Hannequin, Guillaume Fromager, Alexandra Afenjar, Sandra Chantot-Bastaraud, Stéphanie Valence, Perrine Charles, Patrick Berquin, Caroline Rooryck, Julie Bouron, Alexis Brice, Didier Lacombe, Rodrigue Rossignol, Giovanni Stevanin, Giovanni Benard, Lydie Burglen, Alexandra Durr, Cyril Goizet, Isabelle Coupry
OBJECTIVE: Autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) is caused by mutations in the SACS gene. SACS encodes sacsin, a protein whose function remains unknown, despite the description of numerous protein domains and the recent focus on its potential role in the regulation of mitochondrial physiology. This study aimed to identify new mutations in a large population of ataxic patients and to functionally analyze their cellular effects in the mitochondrial compartment...
December 2015: Annals of Neurology
Olivier Allais, Fabrice Etilé, Sébastien Lecocq
The public-health community views mandatory Front-of-Pack (FOP) nutrition labels and nutritional taxes as promising tools to control the growth of food-related chronic diseases. This paper uses household scanner data to propose an ex-ante evaluation and comparison of these two policy options for the fromage blanc and dessert yogurt market. In most markets, labelling is voluntary and firms display fat labels only on the FOP of low-fat products to target consumers who do not want to eat fat. We here separately identify consumer preferences for fat and for FOP fat labels by exploiting an exogenous difference in legal labelling requirements between these two product categories...
September 2015: Journal of Health Economics
Abdelhalim Bencheikh, Michael Fromager, Kamel Aït Ameur
In recent years, considerable attention has been devoted to laser beams with specific intensity profile, i.e., non-Gaussian. In this work, we present a novel technique to generate high-radial-order Laguerre-Gaussian beams LG(p0) based on the use of a binary phase diffractive optical element (BPDOE). The latter is a phase plate made up of annular zones introducing alternatively a phase shift equal to 0 or π modeled on positions which do not coincide with the position of the zeros of the desired LG(p0) beam...
July 20, 2014: Applied Optics
Thomas Godin, Michael Fromager, Emmanuel Cagniot, Marc Brunel, Kamel Aït-Ameur
We propose a new device that is able to perform highly sensitive wavefront measurements based on the use of continuous position sensitive detectors and without resorting to any reconstruction process. We demonstrate experimentally its ability to measure small wavefront distortions through the characterization of pump-induced refractive index changes in laser material. In addition, it is shown using computer-generated holograms that this device can detect phase discontinuities as well as improve the quality of sharp phase variations measurements...
December 1, 2013: Applied Optics
Erik Donovan Hedegård, Frank Heiden, Stefan Knecht, Emmanuel Fromager, Hans Jørgen Aagaard Jensen
Charge transfer excitations can be described within Time-Dependent Density Functional Theory (TD-DFT), not only by means of the Coulomb Attenuated Method (CAM) but also with a combination of wave function theory and TD-DFT based on range separation. The latter approach enables a rigorous formulation of multi-determinantal TD-DFT schemes where excitation classes, which are absent in conventional TD-DFT spectra (like for example double excitations), can be addressed. This paper investigates the combination of both the long-range Multi-Configuration Self-Consistent Field (MCSCF) and Second Order Polarization Propagator Approximation (SOPPA) ansätze with a short-range DFT (srDFT) description...
November 14, 2013: Journal of Chemical Physics
Alexandrina Stoyanova, Andrew M Teale, Julien Toulouse, Trygve Helgaker, Emmanuel Fromager
The alternative separation of exchange and correlation energies proposed by Toulouse et al. [Theor. Chem. Acc. 114, 305 (2005)] is explored in the context of multi-configuration range-separated density-functional theory. The new decomposition of the short-range exchange-correlation energy relies on the auxiliary long-range interacting wavefunction rather than the Kohn-Sham (KS) determinant. The advantage, relative to the traditional KS decomposition, is that the wavefunction part of the energy is now computed with the regular (fully interacting) Hamiltonian...
October 7, 2013: Journal of Chemical Physics
Gaël Nicolas, Cyril Pottier, Camille Charbonnier, Lucie Guyant-Maréchal, Isabelle Le Ber, Jérémie Pariente, Pierre Labauge, Xavier Ayrignac, Luc Defebvre, David Maltête, Olivier Martinaud, Romain Lefaucheur, Olivier Guillin, David Wallon, Boris Chaumette, Philippe Rondepierre, Nathalie Derache, Guillaume Fromager, Stéphane Schaeffer, Pierre Krystkowiak, Christophe Verny, Snejana Jurici, Mathilde Sauvée, Marc Vérin, Thibaud Lebouvier, Olivier Rouaud, Christel Thauvin-Robinet, Stéphane Rousseau, Anne Rovelet-Lecrux, Thierry Frebourg, Dominique Campion, Didier Hannequin
Idiopathic basal ganglia calcification is characterized by mineral deposits in the brain, an autosomal dominant pattern of inheritance in most cases and genetic heterogeneity. The first causal genes, SLC20A2 and PDGFRB, have recently been reported. Diagnosing idiopathic basal ganglia calcification necessitates the exclusion of other causes, including calcification related to normal ageing, for which no normative data exist. Our objectives were to diagnose accurately and then describe the clinical and radiological characteristics of idiopathic basal ganglia calcification...
November 2013: Brain: a Journal of Neurology
Boualem Boubaha, Darryl Naidoo, Thomas Godin, Michael Fromager, Andrew Forbes, Kamel Aït-Ameur
In this paper, we explore theoretically and experimentally the laser beam shaping ability resulting from the coaxial superposition of two coherent Gaussian beams (GBs). This technique is classified under interferometric laser beam shaping techniques contrasting with the usual ones based on diffraction. The experimental setup does not involve the use of some two-wave interferometer but uses a spatial light modulator for the generation of the necessary interference term. This allows one to avoid the thermal drift occurring in interferometers and gives a total flexibility of the key parameter setting the beam transformation...
August 10, 2013: Applied Optics
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