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https://www.readbyqxmd.com/read/28732352/cerebral-blood-flow-changes-in-remitted-early-and-late-onset-depression-patients
#1
Wenxiang Liao, Ze Wang, Xiangrong Zhang, Hao Shu, Zan Wang, Duan Liu, Zhijun Zhang
Abnormal cerebral blood flow (CBF) is reportedly associated with major depressive disorder (MDD). We have investigated CBF changes in early-onset depression (EOD) and late-onset depression (LOD), and their impact on cognitive function. Thirty-two remitted EOD patients, 32 remitted LOD patients, and 43 age-matched healthy controls were recruited, and the pulsed arterial spin labeling data were scanned under 3.0T MRI and processed through voxel-by-voxel statistical analysis. Compared to healthy controls, LOD patients had decreased normalized CBF in the bilateral precuneus, cuneus, right fronto-cingulate-striatal areas, and right temporal, occipital and parietal lobes, but increased normalized CBF in the left frontal and temporal cortices and the cingulate gyrus...
July 12, 2017: Oncotarget
https://www.readbyqxmd.com/read/28732327/prediagnostic-serum-calcium-and-albumin-and-ovarian-cancer-a-nested-case-control-study-in-the-norwegian-janus-serum-bank-cohort
#2
Gary G Schwartz, Steinar Tretli, Linda Vos, Trude E Robsahm
BACKGROUND: Women with higher serum calcium may be more likely to be diagnosed and die of ovarian cancer. We evaluated that finding in a large, prospective cohort. METHODS: We conducted a nested case-control study using a population-based biobank from Norway. We compared 202 ovarian cancer cases and 202 controls, matched for age, date at blood draw, and county of residence, with respect to serum calcium and albumin, adjusted for anthropometric variables. We evaluated risks using the entire follow-up period as well as 2-15 years and 16-25 years ("early" and "late", respectively)...
July 18, 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/28732324/anti-m%C3%A3-llerian-hormone-amh-levels-in-premenopausal-breast-cancer-patients-treated-with-taxane-based-adjuvant-chemotherapy-a-translational-research-project-of-the-success-a-study
#3
E K Trapp, J Steidl, B Rack, M S Kupka, U Andergassen, J Jückstock, A Kurt, T Vilsmaier, A de Gregorio, N de Gregorio, M Tzschaschel, C Lato, A Polasik, H Tesch, A Schneeweiss, M W Beckmann, P A Fasching, W Janni, V Müller
BACKGROUND: Premenopausal women undergoing chemotherapy are at high risk for premature ovarian failure and its long-term consequences. Data on potential markers to evaluate ovarian reserve pre- and posttreatment are limited. Anti-Müllerian hormone (AMH) known for ovarian reserve in reproductive medicine could be a surrogate marker and was assessed in premenopausal breast cancer patients of the SUCCESS A study (EUDRA-CT no. 2005-000490-21). METHODS: We identified 170 premenopausal patients, age ≤ 40 years at trial entry, who received FEC-Doc as taxane-anthracylince based chemotherapy...
July 18, 2017: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/28732236/neighborhood-ses-is-particularly-important-to-the-cardiovascular-health-of-low-ses-individuals
#4
Jennifer Morozink Boylan, Stephanie A Robert
RATIONALE: Health disparities defined by neighborhood socioeconomic status (SES) are well established; it is less well understood whether neighborhood SES is differentially associated with health depending on one's own SES. OBJECTIVE: The double jeopardy hypothesis, collective resources model, fundamental cause theory, and relative deprivation hypothesis support differential patterns of association between neighborhood and individual SES with health. The first three models suggest that higher neighborhood SES predicts health more strongly among lower, as compared to higher, SES individuals...
July 8, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28732218/invasiveness-of-tibial-bone-graft-harvesting-for-secondary-alveolar-bone-grafting-can-harvesting-be-made-at-the-age-of-less-than-10%C3%A2-years-without-complications
#5
Kohta Fukuta, Kenichi Kurita, Atsushi Nakayama, Masahito Maeda, Hiroshi Watanabe, Mitsuo Goto
PURPOSE: In this study, particulate cancellous bone marrow was harvested from the tibia for alveolar bone grafting, and postoperative complications at the donor site were compared between patients aged 10 years or older (29 tibias) and those aged younger than 10 years (42 tibias). PATIENTS AND METHODS: Enrolled patients were those who underwent tibial bone graft harvesting at the Department of Oral and Maxillofacial Surgery, Aichi Gakuin University, during a period of 3 years and 1 month from March 2012 through March 2015...
June 24, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28732090/incidence-predictors-and-severity-of-adverse-events-among-whole-blood-donors
#6
Hamdan Almutairi, Mahmoud Salam, Abdulaziz Alajlan, Faisal Wani, Bushra Al-Shammari, Khaled Al-Surimi
BACKGROUND: Adverse events have been reported post blood donation. Donors might refrain from donating again due to such events which lowers the blood supply in collection centers. AIM: This study measured the incidence, predictors and severity of adverse events among donors of a single whole blood unit at one of the largest donation centers in Saudi Arabia. METHODS: A retrospective cohort was conducted in 2015 to investigate the adverse events immediately post donation...
2017: PloS One
https://www.readbyqxmd.com/read/28732072/placental-peptides-metabolism-and-maternal-factors-as-predictors-of-risk-of-gestational-diabetes-in-pregnant-women-a-case-control-study
#7
Robert Amadu Ngala, Linda Ahenkorah Fondjo, Peter Gmagna, Frank Naku Ghartey, Martin Akilla Awe
BACKGROUND: Gestational diabetes is a risk factor for perinatal complications; include shoulder dystocia, birth injuries such as bone fractures and nerve palsies. It is associated with later development of type 2 diabetes, the risk of macrosomia and other long-term health effects of infants born to diabetic mothers. The study assesses placental peptides and maternal factors as potential predictors of gestational diabetes among pregnant women. MATERIAL AND METHODS: A total of 200 pregnant women were recruited for the study, 150 pregnant women without pre gestational diabetes including 50 women with low risk factors of diabetes as controls and 50 other pregnant women with pregestational diabetes as control...
2017: PloS One
https://www.readbyqxmd.com/read/28732058/the-role-of-a-fads1-polymorphism-in-the-association-of-fatty-acid-blood-levels-bmi-and-blood-pressure-in-young-children-analyses-based-on-path-models
#8
Maike Wolters, Carmen Dering, Alfonso Siani, Paola Russo, Jaakko Kaprio, Patrizia Risé, Luis A Moreno, Stefaan De Henauw, Kirsten Mehlig, Toomas Veidebaum, Denés Molnár, Michael Tornaritis, Licia Iacoviello, Yannis Pitsiladis, Claudio Galli, Ronja Foraita, Claudia Börnhorst
BACKGROUND: The recent obesity epidemic in children also showed an increase in the prevalence of hypertension. As blood pressure (BP) is associated with (long-chain) polyunsaturated fatty acids (LC PUFA), genetic variation in desaturase enzymes being involved in the synthesis of LC PUFA may be associated with BP. This study aimed to investigate the direct effects (independent of mediating variables) and indirect effects (mediated through intermediate variables) of a common variant in the FADS1 gene, rs174546, known to affect delta-5 desaturase (D5D) activity on PUFA level, body mass index (BMI) and BP...
2017: PloS One
https://www.readbyqxmd.com/read/28732019/rate-of-hepatitis-c-viral-clearance-by-human-livers-in-human-patients-liver-transplantation-modeling-primary-infection-and-implications-for-studying-entry-inhibition
#9
Michael G Hughes, William W Tucker, Sreelatha Reddy, Michael E Brier, David Koch, Craig J McClain, Colleen B Jonsson, Nobuyuki Matoba, Donghoon Chung
To better understand the dynamics of early hepatitis C virus (HCV) infection, we determined how rapidly non-cirrhotic HCV-uninfected liver allografts clear HCV from the circulation of cirrhotic HCV-infected patients at the time of transplantation but before administration of immunosuppression. Specifically, we characterized serum HCV kinetics during the first 90 min of reperfusion for 19 chronically HCV-infected patients transplanted with an HCV-uninfected liver by measuring serum viral load immediately prior to reperfusion (t = 0) and then every 15 min for a total of 90 min (t = 90)...
2017: PloS One
https://www.readbyqxmd.com/read/28731931/renal-function-and-its-association-with-blood-pressure-in-middle-eastern-immigrants-and-native-swedes
#10
Christopher Nilsson, Anders Christensson, Peter M Nilsson, Louise Bennet
BACKGROUND: Iraqi-born immigrants residing in Sweden are at high risk for type 2 diabetes, obesity and hyperlipidemia compared with native Swedes. Paradoxically, hypertension is less prevalent in this immigrant population. The aim of this study was to investigate differences in renal function and further if differences in blood pressure (BP) levels were associated with differences across ethnicities in renal function as a possible explanation to the paradox. METHODS: A population-based, cross-sectional study of men and women, born in Iraq or Sweden, aged 30-75 years was conducted in Malmö, Sweden, from 2010 to 2012...
July 20, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28731867/specific-skin-lesions-of-sarcoidosis-located-at-venipuncture-points-for-blood-sample-collection
#11
Joaquim Marcoval, Rosa M Penín, Juan Mañá
It has been suggested that the predilection of sarcoidosis to affect scars is due to the presence of antigens or foreign bodies that can serve as a stimulus for granuloma formation. Several patients with sarcoidosis-specific skin lesions in venous puncture sites have been reported. However, in these patients the pathogenesis of the cutaneous lesions is not clear because the presence of foreign bodies is not to be expected. Our objective was to describe 3 patients who developed specific lesions of sarcoidosis in areas of venipuncture and to discuss their possible pathogenesis...
July 8, 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/28731653/insulin-level-and-insulin-sensitivity-indices-among-healthy-children-and-adolescents
#12
María G Ballerini, Ignacio Bergadá, María E Rodríguez, Ana Keselman, Viviana S Bengolea, Viviana Pipman, Horacio M Domené, Héctor G Jasper, María G Ropelato
INTRODUCTION: Information on insulin reference values and insulin sensitivity indices in the field of pediatrics is scarce. OBJETIVE: To describe insulin range and insulin sensitivity surrogate indices during childhood. POPULATION AND METHODS: Fasting insulin level range and surrogate indices, such as the homeostasis model assessment of insulin resistance (HOMA-IR), among healthy children and adolescents by age, body mass index, pubertal stage (PS), insulin-like growth factor-1 (IGF-1), total cholesterol, and triglycerides...
August 1, 2017: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/28731609/dietary-sodium-and-potassium-intake-and-their-association-with-blood-pressure-in-a-non-hypertensive-iranian-adult-population-isfahan-salt-study
#13
Noushin Mohammadifard, Arsalan Khaledifar, Alireza Khosravi, Fatemeh Nouri, Ali Pourmoghadas, Awat Feizi, Ahmad Esmaillzadeh, Nizal Sarrafzadegan
AIM: The association of sodium (Na) and potassium (K) intake with blood pressure (BP) is an ongoing debate, especially in central Iran. We aimed to examine the mean Na and K intake, major sources of Na and the relationship between BP and dietary and urinary Na and K. METHODS: This cross-sectional study was performed in central Iran in 2013-2014. A total of 796 non-hypertensive adults aged >18 years were randomly recruited. The semi-quantitative food frequency questionnaire was used to assess dietary Na and K intake...
July 2017: Nutrition & Dietetics: the Journal of the Dietitians Association of Australia
https://www.readbyqxmd.com/read/28731561/association-of-glycaemic-index-and-glycaemic-load-with-metabolic-syndrome-in-an-iranian-adult-population-isfahan-healthy-heart-program
#14
Noushin Mohammadifard, Marjan Mansourian, Firouzeh Sajjadi, Maryam Maghroun, Ali Pourmoghaddas, Narges Yazdekhasti, Nizal Sarrafzadegan
AIM: There is controversy around the clinical effects of the dietary glycaemic index (GI) and glycaemic load (GL) on cardiovascular diseases risk factors such as metabolic syndrome (MetS). So, the present study was performed to evaluate the relationship between GI or GL and metabolic syndrome in an Iranian adult population in 2007. METHODS: The study was based on data from a sub-sample of the Isfahan Healthy Heart Program (IHHP), collected across three cities in central Iran, in the year 2007...
February 2017: Nutrition & Dietetics: the Journal of the Dietitians Association of Australia
https://www.readbyqxmd.com/read/28731559/association-between-anthropometric-measures-of-regional-fat-mass-and-heart-rate-variability-in-obese-women
#15
Marina Rastović, Biljana Srdić-Galić, Oto Barak, Edita Stokić
AIM: Impaired autonomic function could be the mechanism for the development of cardiometabolic diseases in obesity. Hence, simple anthropometric measures of overall and central obesity could be screening markers for autonomic imbalance. We analysed the relationship between heart rate variability (HRV) parameters and obesity indicators. METHODS: Sixty-three obese women underwent blood pressure, lipids and anthropometric measurements, body composition assessment, HOMA (homeostasis model assessment) index calculation and short-term HRV analysis...
February 2017: Nutrition & Dietetics: the Journal of the Dietitians Association of Australia
https://www.readbyqxmd.com/read/28731539/interleukin-17a-gene-polymorphism-rs2275913-is-associated-with-osteitis-after-the-bacillus-calmette-gu%C3%A3-rin-vaccination
#16
Milla Liehu-Martiskainen, Matti Korppi, Johanna Teräsjärvi, Juho Vuononvirta, Heini Huhtala, Kirsi Nuolivirta, Liisa Kröger, Ville Peltola, Laura Pöyhönen, Qiushui He
AIM: Interleukin-17 (IL-17) appears to promote the host's defense against mycobacterial infections. This study evaluated the association between IL17A gene polymorphism and the risk of Bacillus Calmette-Guérin (BCG) osteitis after newborn vaccination and between IL17A gene polymorphism and IL-17A concentrations in serum. METHODS: IL17A rs2275913 gene polymorphisms and serum IL-17A concentrations were studied in 132 adults aged 21-49 years from across Finland, who had BCG osteitis in infancy after a newborn BCG vaccination...
July 21, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28731289/current-status-of-achieving-blood-pressure-target-and-its-clinical-correlates-in-japanese-type-2-diabetes
#17
Hiroki Yokoyama, Shin-Ichi Araki, Koichi Kawai, Koichi Hirao, Yoshio Kurihara, Hiroaki Seino, Hiroshi Takamura, Hidekatsu Sugimoto, Akira Okada, Hiroshi Maegawa
AIMS/INTRODUCTION: To investigate the current status of achieved blood pressure levels in association with the number of antihypertensive drug classes as of 2013, and to explore the clinical correlates with achievement of target blood pressure in a large-scale cohort of Japanese subjects with type 2 diabetes. MATERIALS AND METHODS: A nationwide survey was conducted including 12,811 subjects with type 2 diabetes. Subjects were divided by achieved blood pressure, <130/80 or 140/90 mmHg, and the number of drug classes taken...
July 21, 2017: Journal of Diabetes Investigation
https://www.readbyqxmd.com/read/28731129/expression-profile-of-c19mc-micrornas-in-placental-tissue-of-patients-with-preterm-prelabor-rupture-of-membranes-and-spontaneous-preterm-birth
#18
Ilona Hromadnikova, Katerina Kotlabova, Katarina Ivankova, Ladislav Krofta
The aim of the study was to demonstrate that preterm birth (PTB) is associated with altered C19MC microRNA expression profile in placental tissues. Gene expression of 15 placental specific microRNAs (miR‑512‑5p, miR‑515‑5p, miR‑516‑5p, miR‑517‑5p, miR‑518b, miR‑518f‑5p, miR‑519a, miR‑519d, miR‑519e‑5p, miR‑520a‑5p, miR‑520h, miR‑524‑5p, miR‑525‑5p, miR‑526a and miR‑526b‑5p) was compared between groups: 34 spontaneous PTB, 108 preterm prelabor rupture of membranes (PPROM) and 20 term in labor pregnancies...
July 21, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28730870/cardiac-autonomic-recovery-after-strength-exercise-in-lower-and-upper-limbs
#19
Naerton José Xavier Isidoro, Milana Drumond Ramos Santana, Vitor E Valenti, David M Garner, Luiz Carlos de Abreu
Introduction Strength exercises influence the cardiovascular system by promoting autonomic adjustments induced by the increased metabolic demand and consequent increase in local blood flow. However, it is unclear whether there are differences between upper and lower limbs. We aimedto evaluate recovery of cardiac autonomic modulation afterstrengthexercise in upper and lower limbs. Methods We analysed 29 healthy male subjects physically active but not professional athletes aged between 20 and 35 years old...
July 21, 2017: Acta Cardiologica
https://www.readbyqxmd.com/read/28730828/the-effect-of-hypertension-on-adult-hippocampal-neurogenesis-in-young-adult-spontaneously-hypertensive-rats-and-dahl-rats
#20
A Pistikova, H Brozka, M Bencze, D Radostova, K Vales, A Stuchlik
The dentate gyrus of the hippocampus is one of the few places in the brain where neurogenesis occurs in adulthood. Nowadays, an increasing number of children and young adults are affected by hypertension, one of the factors in the development of cerebrovascular diseases and age-related cognitive deficits. Since these cognitive deficits are often hippocampus-dependent, it is possible that hypertension exerts this effect via decreasing adult neurogenesis which has been shown to be essential for a range of cognitive tasks...
July 18, 2017: Physiological Research
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