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https://www.readbyqxmd.com/read/29053933/chronic-administration-of-ellagic-acid-improved-the-cognition-in-male-middle-aged-overweight
#1
Ying Liu, Shuyi Yu, Fen Wang, Haitao Yu, Xueli Li, Wanru Dong, Ruichao Lin, Qingshan Liu
This study aims to investigate whether ellagic acid has beneficial effects on cognitive deficits in middle-aged overweight individuals and the possible mechanism. A total of 150 middle-aged male participants, including 76 normal weight and 74 overweight, aged between 45 to 55 years were recruited for this study. Both normal weight and overweight participants were administered either 50 mg ellagic acid or placebo cellulose daily for 12 weeks. Blood lipids, peripheral brain-derived neurotrophic factor (BDNF) and saliva cortisol were assessed on the last day of the procedure to investigate the effects induced by ellagic acid...
October 20, 2017: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/29053899/peptidergic-nerve-fibers-in-the-urethra-morphological-and-neurochemical-characteristics-in-female-mice-of-reproductive-age
#2
Christine M Barry, Esther Ji, Harman Sharma, Pauline Yap, Nicholas J Spencer, Dusan Matusica, Rainer V Haberberger
BACKGROUND: Peptidergic nerve fibers provide important contributions to urethral function. Urethral innervation of female mice is not well documented. AIMS: To determine the distribution and projection sites of nerve fibers immunoreactive for vasoactive intestinal peptide (VIP), calcitonin gene-related peptide (CGRP), substance P (SP), and neuropeptide Y (NPY) in the urethra of wild-type control mice and compare innervation characteristics between the proximal and distal urethra of young nullipara and older multipara mice...
October 20, 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/29053876/blood-hematological-and-biochemical-constituents-antioxidant-enzymes-immunity-and-lymphoid-organs-of-broiler-chicks-supplemented-with-propolis-bee-pollen-and-mannan-oligosaccharides-continuously-or-intermittently
#3
Y A Attia, H Al-Khalaifah, M S Ibrahim, A E Abd Al-Hamid, M A Al-Harthi, A El-Naggar
This study investigate the effect of bee pollen (BP) and/or propolis (Pro) as an alternative to Mannan oligosaccharides (Bio-MOS, a hydrolyzed yeast with natural and artificial flavors Alltech Inc) when given continuously or intermittently on antioxidant enzymes, immunity, weight and morphology of lymphoid organs of broilers. Thus, 324 unsexed one-day-old Arbor Acres broilers were randomly distributed into nine treatment groups, each replicated 6 times of 6 birds per replicate. The chicks were kept in wire cages and fed the same basal diet and were submitted to the following treatments: control without supplementation (control) or supplemented with BP at 300 mg, Pro at 300 mg, BP+Pro at 300 mg each and Bio-MOS at 0...
October 10, 2017: Poultry Science
https://www.readbyqxmd.com/read/29053848/is-virtual-reality-ready-for-prime-time-in-the-medical-space-a-randomized-control-trial-of-pediatric-virtual-reality-for-acute-procedural-pain-management
#4
Jeffrey I Gold, Nicole E Mahrer
Objective: To conduct a randomized control trial to evaluate the feasibility and efficacy of virtual reality (VR) compared with standard of care (SOC) for reducing pain, anxiety, and improving satisfaction associated with blood draw in children ages 10-21 years. Methods: In total, 143 triads (patients, their caregiver, and the phlebotomist) were recruited in outpatient phlebotomy at a pediatric hospital and randomized to receive either VR or SOC when undergoing routine blood draw...
October 19, 2017: Journal of Pediatric Psychology
https://www.readbyqxmd.com/read/29053816/histomorphometric-study-of-the-anterior-latissimus-dorsi-muscle-and-evaluation-of-enzymatic-markers-of-broilers-affected-with-dorsal-cranial-myopathy
#5
R Sesterhenn, F M Siqueira, A C Hamerski, D Driemeier, S F Valle, S L Vieira, L Kindlein, V P Nascimento
Dorsal cranial myopathy (DCM), which affects the anterior latissimus dorsi (ALD) muscles of commercial broilers, is of unknown etiology, and it represents up to 6% of the partial condemnations in Brazilian slaughterhouses. This study was performed to achieve histomorphometric characterizations of the ALD muscles from male Cobb 500 broilers slaughtered at either 35 d or 42 d and to evaluate the effects of DCM on the enzymatic markers aspartate aminotransferase (AST), alanine aminotransferase (ALT), creatine kinase (CK), and lactate dehydrogenase (LDH) and on uric acid and creatinine metabolites...
September 20, 2017: Poultry Science
https://www.readbyqxmd.com/read/29053810/associations-between-cellular-aging-markers-and-metabolic-syndrome-findings-from-the-cardia-study
#6
Dóra Révész, Josine E Verhoeven, Martin Picard, Jue Lin, Stephen Sidney, Elissa S Epel, Brenda W J H Penninx, Eli Puterman
Background: Metabolic syndrome (MetS) is thought to promote biological aging, which might lead to cardiovascular and aging-related complications. This large-scale study investigated longitudinal relationships between MetS, its components, and cellular aging markers: leukocyte mitochondrial DNA copy number (mtDNAcn) and telomere length (TL). Methods: We included 989 participants from the Coronary Artery Risk Development in Young Adults Study. MtDNAcn (CARDIA Years 15, 25) and TL (Y15, Y20, Y25) were measured using quantitative PCR...
October 18, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29053741/the-importance-of-propolis-in-alleviating-the-negative-physiological-effects-of-heat-stress-in-quail-chicks
#7
Gamal M K Mehaisen, Rania M Ibrahim, Adel A Desoky, Hosam M Safaa, Osama A El-Sayed, Ahmed O Abass
Heat stress is one of the most detrimental confrontations in tropical and subtropical regions of the world, causing considerable economic losses in poultry production. Propolis, a resinous product of worker honeybees, possesses several biological activities that could be used to alleviate the deleterious effects of high environmental temperature on poultry production. The current study was aimed at evaluating the effects of propolis supplementation to Japanese quail (Coturnix coturnix japonica) diets on the production performance, intestinal histomorphology, relative physiological and immunological parameters, and selected gene expression under heat stress conditions...
2017: PloS One
https://www.readbyqxmd.com/read/29053737/screening-for-hiv-hepatitis-b-and-syphilis-on-dried-blood-spots-a-promising-method-to-better-reach-hidden-high-risk-populations-with-self-collected-sampling
#8
Inge H M van Loo, Nicole H T M Dukers-Muijrers, Rosalie Heuts, Marianne A B van der Sande, Christian J P A Hoebe
INTRODUCTION: Many people at high risk for sexually transmitted infections (STIs), e.g., men who have sex with men (MSM), are not optimally reached by current sexual health care systems with testing. To facilitate testing by home-based sampling or sampling in outreach setting we evaluated dried blood spots (DBS), a method for self-collected blood sampling for serological screening of HIV, hepatitis B (HBV) and syphilis. The aims of this study were to assess the acceptability and feasibility of self-collected DBS and to compare the test results for screening of HIV, HBV and syphilis from DBS with blood drawn by venous puncture...
2017: PloS One
https://www.readbyqxmd.com/read/29053723/heart-rate-variability-and-baroreceptor-reflex-sensitivity-in-early-versus-late-onset-preeclampsia
#9
Thomas Michael Weber, Helmut Karl Lackner, Andreas Roessler, Ilona Papousek, Vassiliki Kolovetsiou-Kreiner, Miha Lucovnik, Karin Schmid-Zalaudek, Uwe Lang, Manfred Georg Moertl
OBJECTIVE: To determine whether there are differences in autonomic nervous system function in early- versus late-onset preeclampsia. METHODS: Matched case-control study. Cases were defined as singleton pregnancies with preeclampsia at < 34+0 weeks of gestation (early-onset preeclampsia) and ≥ 34+0 weeks of gestation (late-onset preeclampsia). For each case in each of the preeclampsia subgroups, three "control"uncomplicated singleton pregnancies were matched by maternal age, height, and week of gestation...
2017: PloS One
https://www.readbyqxmd.com/read/29053123/-indices-of-the-antioxidant-system-and-dopamine-in-blood-plasma-in-the-dynamics-of-microwave-resonance-therapy-in-patients-with-alcoholism
#10
V D Prokopieva, E G Yarygina, N M Krotenko, A S Boiko, N A Bokhan, S A Ivanova
AIM: To study effects of microwave resonance therapy (MWRT) on the level of dopamine and some indices of the antioxidant system of blood plasma in patients with alcohol dependence. MATERIAL AND METHODS: Dopamine, reduced glutathione, activities of catalase and superoxidismutase (SOD) were measured in blood plasma of alcoholic patients (50 men) before and after therapy. Plasma of 25 physically and mentally healthy men matched for age was used as control. RESULTS: In alcoholic patients in withdrawal state, the significant increase in dopamine (p=0...
2017: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/29052799/treatment-and-outcome-of-subdural-hematoma-in-patients-with-spontaneous-intracranial-hypotension-a-report-of-35-cases
#11
Enrico Ferrante, Fabio Rubino, Federica Beretta, Caroline Regna-Gladin, M Mirko Ferrante
Spontaneous intracranial hypotension (SIH) is characterized by orthostatic headache, low CSF pressure and diffuse pachymeningeal enhancement on brain MRI. SIH results from spontaneous CSF leakage leading to brain sag. Sometimes, tearing of bridging veins may produce subdural hematomas (SDHs). Patients with SDH were identified retrospectively from 212 consecutive SIH patients. Data were collected on demographics, clinical courses, neuroimaging findings, treatment and outcome of SDH. Thirty-five patients (16%), (6 women, 29 men; aged 33-68; mean, 50 years) with SDH were recruited...
October 20, 2017: Acta Neurologica Belgica
https://www.readbyqxmd.com/read/29052564/reference-intervals-of-mitochondrial-dna-copy-number-in-peripheral-blood-for-chinese-minors-and-adults
#12
Chang-Yu Xia, Yu Liu, Hui-Rong Yang, Hong-Yun Yang, Jing-Xia Liu, Yi-Nan Ma, Yu Qi
BACKGROUND: Mitochondrial DNA (mtDNA) content measured by different techniques cannot be compared between studies, and age- and tissue-related control values are hardly available. In the present study, we aimed to establish the normal reference range of mtDNA copy number in the Chinese population. METHODS: Two healthy cohorts of 200 Chinese minors (0.1-18.0 years) and 200 adults (18.0-88.0 years) were recruited. Then, they were further categorized into eight age groups...
October 20, 2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/29052558/cesarean-section-rate-in-singleton-primiparae-and-related-factors-in-beijing-china
#13
Geng Song, Yu-Mei Wei, Wei-Wei Zhu, Hui-Xia Yang
BACKGROUND: The cesarean section rate (CSR) has been a main concern worldwide. The present study aimed to investigate the CSR in Beijing, China, and to analyze the related factors of CS delivery. METHODS: An observational study was conducted in 15 medical centers in Beijing using a systemic cluster sampling method. In total, 15,194 pregnancies were enrolled in the study between June 20, 2013 and November 30, 2013. Independent t-tests and Pearson's Chi-square test were used to examine differences between two groups, and related factors of the CSR were examined by multivariable logistic regression...
October 20, 2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/29052521/high-seroprevalance-of-neospora-caninum-in-dogs-in-victoria-australia-compared-to-20%C3%A2-years-ago
#14
Sarah Sloan, Jan Šlapeta, Abdul Jabbar, Jaimie Hunnam, Bert De Groef, Grant Rawlin, Christina McCowan
BACKGROUND: Canids are definitive hosts of the apicomplexan parasite Neospora caninum, the leading cause of abortion in cattle worldwide. For horizontal transmission from canids to occur, oocysts of N. caninum must be shed by the definitive host into the environment of susceptible intermediate hosts such as cattle. The purpose of this study was to determine the prevalence of N. caninum in canids in Victoria, Australia's leading dairy producing state. RESULTS: Neospora-like oocysts were observed in 8% (18/234) of faecal samples from wild dogs, domestic dogs and red foxes from Victoria, Australia...
October 19, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/29052349/relationship-between-ugt1a1-27-and-ugt1a1-7-polymorphisms-and-irinotecan-related-toxicities-in-patients-with-lung-cancer
#15
Minoru Fukuda, Manabu Okumura, Tomomi Iwakiri, Kazuhiko Arimori, Takuya Honda, Kazuma Kobayashi, Hiroaki Senju, Shinnosuke Takemoto, Takaya Ikeda, Hiroyuki Yamaguchi, Katsumi Nakatomi, Nobuko Matsuo, Hiroshi Mukae, Kazuto Ashizawa
BACKGROUND: The objective of this study was to evaluate the effects of gene polymorphisms, including UGT1A1*7, *27, and *29, on the safety of irinotecan therapy. METHODS: The eligibility criteria were: lung cancer patients scheduled to undergo irinotecan therapy, aged ≥ 20 years, with a performance status of 0-2. Thirty-one patients were enrolled and their blood was collected and used to examine the frequency of UGT1A1*6, *7, *27, *28, and *29 polymorphisms and the concentrations of irinotecan, SN-38, and SN-38G after irinotecan therapy...
October 20, 2017: Thoracic Cancer
https://www.readbyqxmd.com/read/29052340/absence-of-neurocognitive-disadvantage-associated-with-paediatric-hiv-subtype-a-infection-in-children-on-antiretroviral-therapy
#16
Paul Bangirana, Theodore D Ruel, Michael J Boivin, Satish K Pillai, Leila B Giron, Alla Sikorskii, Asish Banik, Jane Achan
INTRODUCTION: Infection with HIV subtype A has been associated with poorer neurocognitive outcomes compared to HIV subtype D in Ugandan children not eligible for antiretroviral therapy (ART). In this study, we sought to determine whether subtype-specific differences are also observed among children receiving ART. MATERIALS AND METHODS: Children were recruited from a clinical trial in which they were randomized to receive either lopinavir (LPV)- or non-nucleoside reverse transcriptase inhibitor (NNRTI)- based ART (NCT00978068)...
October 2017: Journal of the International AIDS Society
https://www.readbyqxmd.com/read/29052257/utility-of-reproductive-life-plans-in-identification-of-potentially-teratogenic-medication-use-a-pilot-study
#17
Natalie DiPietro Mager, Caitlin Mills, April Snelling
BACKGROUND: Teratogenic medications increase risks of miscarriage, fetal death, and/or birth defects. It is important to identify whether women of childbearing potential are taking these medications and to minimize exposure to these agents through change in drug therapy before conception and/or use of effective contraception to prevent conception. OBJECTIVE: To determine the utility of reproductive life plans as tools to identify women using potentially teratogenic medications...
October 20, 2017: Birth
https://www.readbyqxmd.com/read/29052216/polycystic-ovarian-syndrome-prevalence-and-impact%C3%A2-on-the-wellbeing-of-australian-women-aged-16-29%C3%A2-years
#18
L Chitra Varanasi, Asvini Subasinghe, Yasmin L Jayasinghe, Emma T Callegari, Suzanne M Garland, Alexandra Gorelik, John D Wark
BACKGROUND: Polycystic ovarian syndrome (PCOS) is the most common condition among reproductive-aged women. However, its exact prevalence is unknown. AIMS: To determine the prevalence of PCOS in Australian women aged 16-29 years using the National Institutes of Health (NIH) criteria compared to self-reported PCOS, to compare co-morbidities between the groups and to determine the most distressing aspect of a diagnosis of PCOS for these young women. MATERIALS AND METHODS: Participants were recruited from the Young Female Health Initiative (YFHI) and Safe-D studies...
October 19, 2017: Australian & New Zealand Journal of Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/29051578/associations-of-blood-pressure-with-the-factors-among-adults-in-jilin-province-a-cross-sectional-study-using-quantile-regression-analysis
#19
Junsen Ye, Zhongmin Li, Yaogai Lv, Lan An, Jianxing Yu, Xin Guo, Yan Yao, Yaqin Yu, Lina Jin
Hypertension has become a major public health challenge. However, numerous research results reported in the literature focus primarily on risk factors of hypertension, little is known about how the whole continuum of blood pressure (BP) is associated with risk factors of hypertension. This study aims to reveal quantile-specific associations of BP with its risk factors. A cross-sectional survey based on a sample of 23,050 adults aged 18 to 79 years was conducted in Jilin Province in 2012, and some subjects were excluded due to missing values in BP or having BP control according to the purpose of this study...
October 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29051544/estimating-prognosis-in-patients-with-acute-myocardial-infarction-using-personalized-computational-heart-models
#20
Hao Gao, Kenneth Mangion, David Carrick, Dirk Husmeier, Xiaoyu Luo, Colin Berry
Biomechanical computational models have potential prognostic utility in patients after an acute ST-segment-elevation myocardial infarction (STEMI). In a proof-of-concept study, we defined two groups (1) an acute STEMI group (n = 6, 83% male, age 54 ± 12 years) complicated by left ventricular (LV) systolic dysfunction; (2) an age- and sex- matched hyper-control group (n = 6, 83% male, age 46 ± 14 years), no prior history of cardiovascular disease and normal systolic blood pressure (SBP < 130 mmHg)...
October 19, 2017: Scientific Reports
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