Han S J Cheong, Kaitlyn N Boone, Marryn M Bennett, Farzaan Salman, Jacob D Ralston, Kaleb Hatch, Raven F Allen, Alec M Phelps, Andrew P Cook, Jasper S Phelps, Mert Erginkaya, Wei-Chung A Lee, Gwyneth M Card, Kevin C Daly, Andrew M Dacks
Natural behaviors are a coordinated symphony of motor acts that drive reafferent (self-induced) sensory activation. Individual sensors cannot disambiguate exafferent (externally induced) from reafferent sources. Nevertheless, animals readily differentiate between these sources of sensory signals to carry out adaptive behaviors through corollary discharge circuits (CDCs), which provide predictive motor signals from motor pathways to sensory processing and other motor pathways. Yet, how CDCs comprehensively integrate into the nervous system remains unexplored...
February 13, 2024: Current Biology: CB