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https://www.readbyqxmd.com/read/29771089/-an-analysis-of-electrocochleography-in-patients-with-osahs
#1
W T Sun, Y Chen, H H Lu, H Y Ruan, R M Liang, C Chen, J P Zhang
Objective: To investigate the values of electrocochleograph(ECochG)in patients with OSAHS. Method: ECochG was performed in 31 (62 ears) OSAHS patients (moderately 5 cases, severely 26 cases) and 28 healthy adults (56 ears). AP latency ,AP amplitude and SP/AP were measured and analyzed. Result: There was no difference between the two groups in SP/AP amplitude ratio( P >0.05) while both AP latency( P <0.05) and AP amplitude( P <0.05) were significantly different. Conclusion: ECochG can confirm the damage of cochlear and auditory nerve near the cochlear segment in patients with moderate to severe OSAHS...
May 2018: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
https://www.readbyqxmd.com/read/29764779/patients-over-60-years-of-age-have-poor-prognosis-in-facial-nerve-decompression-surgery-with-preserved-ossicular-chain
#2
Norio Kondo, Yukie Yamamura, Manabu Nonaka
OBJECTIVE: We report our retrospective study of the recovery rate of auditory ossicles preserved facial nerve decompression surgery via the transmastoid approach in cases of both an electroneurography score of < 10% and a Yanagihara score of ≤8 in Bell's palsy and Ramsay Hunt syndrome. MATERIALS AND METHODS: We retrospectively reviewed 47 patients who we were able to follow-up for more than 6 months following the onset of palsy. The recovery rate was defined by the Japan Society for Facial Nerve Research or the Yanagihara score...
April 2018: Journal of International Advanced Otology
https://www.readbyqxmd.com/read/29764030/-neuroendoscopy-assisted-microneurosurgery-for-posterior-cranial-fossa-lesion
#3
J Li, D Zhong, D Lü, H Y Huang, W Du, J Yang, Y T Wu, H J Xia, W Y Tang, X C Sun
Objective: To study the value of neuroendoscopy assisted microneurosurgery technique in the treatment of posterior cranial fossa lesion. Methods: Clinical data of 36 patients with posterior fossa lesions who accepted neuroendoscopy assisted microneurosurgery (NEAM group) in the department of neurosurgery of the First Affiliated Hospital of Chongqing Medical University, from January 2014 to December 2016, were retrospectively enrolled. A total of 113 cases diagnosed with the same lesions and accepted conventional microneurosurgery (non-NEAM group) in the same period were analyzed as control group...
May 8, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/29750273/video-head-impulse-test-to-preoperatively-identify-the-nerve-of-origin-of-vestibular-schwannomas
#4
Felipe Constanzo, Patricia Sens, Bernardo Corrêa de Almeida Teixeira, Ricardo Ramina
BACKGROUND: Identification of the nerve of origin in vestibular schwannoma (VS) is an important prognostic factor for hearing preservation surgery. Thus far, vestibular functional tests and magnetic resonance imaging have not yielded reliable results to preoperatively evaluate this information. The development of the video head impulse test (vHIT) has allowed a precise evaluation of each semicircular canal, and its localizing value has been tested for some peripheral vestibular diseases, but not for VS...
May 10, 2018: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/29744730/persistent-auditory-nerve-damage-following-kainic-acid-excitotoxicity-in-the-budgerigar-melopsittacus-undulatus
#5
Kenneth S Henry, Kristina S Abrams
Permanent loss of auditory nerve (AN) fibers occurs with increasing age and sound overexposure, sometimes without hair cell damage or associated audiometric threshold elevation. Rodent studies suggest effects of AN damage on central processing and behavior, but these species have limited capacity to discriminate low-frequency speech-like sounds. Here, we introduce a new animal model of AN damage in an avian communication specialist, the budgerigar (Melopsittacus undulatus). The budgerigar is a vocal learner and speech mimic with sensitive low-frequency hearing and human-like behavioral sensitivity to many complex signals including speech components...
May 9, 2018: Journal of the Association for Research in Otolaryngology: JARO
https://www.readbyqxmd.com/read/29744729/supra-threshold-hearing-and-fluctuation-profiles-implications-for-sensorineural-and-hidden-hearing-loss
#6
REVIEW
Laurel H Carney
An important topic in contemporary auditory science is supra-threshold hearing. Difficulty hearing at conversational speech levels in background noise has long been recognized as a problem of sensorineural hearing loss, including that associated with aging (presbyacusis). Such difficulty in listeners with normal thresholds has received more attention recently, especially associated with descriptions of synaptopathy, the loss of auditory nerve (AN) fibers as a result of noise exposure or aging. Synaptopathy has been reported to cause a disproportionate loss of low- and medium-spontaneous rate (L/MSR) AN fibers...
May 9, 2018: Journal of the Association for Research in Otolaryngology: JARO
https://www.readbyqxmd.com/read/29742889/intraoperative-neurophysiological-monitoring-a-review-of-techniques-used-for-brain-tumor-surgery-in-children
#7
REVIEW
Keewon Kim, Charles Cho, Moon-Suk Bang, Hyung-Ik Shin, Ji-Hoon Phi, Seung-Ki Kim
Intraoperative monitoring (IOM) utilizes electrophysiological techniques as a surrogate test and evaluation of nervous function while a patient is under general anesthesia. They are increasingly used for procedures, both surgical and endovascular, to avoid injury during an operation, examine neurological tissue to guide the surgery, or to test electrophysiological function to allow for more complete resection or corrections. The application of IOM during pediatric brain tumor resections encompasses a unique set of technical issues...
May 2018: Journal of Korean Neurosurgical Society
https://www.readbyqxmd.com/read/29729847/siope-brain-tumor-group-consensus-guideline-on-craniospinal-target-volume-delineation-for-high-precision-radiotherapy
#8
Thankamma Ajithkumar, Gail Horan, Laetitia Padovani, Nicky Thorp, Beate Timmermann, Claire Alapetite, Lorenza Gandola, Monica Ramos, Karen Van Beek, Melissa Christiaens, Yasmin Lassen-Ramshad, Henriette Magelssen, Kristina Nilsson, Frank Saran, Barbara Rombi, Rolf Kortmann, Geert O Janssens
OBJECTIVE: To develop a consensus guideline for craniospinal target volume (TV) delineation in children and young adults participating in SIOPE studies in the era of high-precision radiotherapy. METHODS AND MATERIALS: During four consensus meetings (Cambridge, Essen, Liverpool, and Marseille), conventional field-based TV has been translated into image-guided high-precision craniospinal TV by a group of expert paediatric radiation oncologists and enhanced by MRI images of liquor distribution...
May 2, 2018: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/29728875/natural-history-and-clinical-characteristics-of-50-patients-with-wolfram-syndrome
#9
Gema Esteban Bueno, Dyanne Ruiz-Castañeda, Javier Ruiz Martínez, Manuel Romero Muñoz, Pedro Carrillo Alascio
PURPOSE: To describe clinical characteristics of diabetes mellitus (DM) in a group of patients with Wolfram Syndrome (WS). METHODS: Descriptive, cross-sectional observational design. The sample consisted of 50 patients diagnosed with WS. Clinical criteria contributing to WS diagnosis were analyzed: diabetes mellitus (DM), optic nerve atrophy (OA), sensorineural deafness, urological and neurological dysfunction, among others. These parameters were assessed according to their presence/absence, age of onset, and various clinical-analytical parameters...
May 4, 2018: Endocrine
https://www.readbyqxmd.com/read/29724652/a-novel-homozygous-ndrg1-mutation-in-a-chinese-patient-with-charcot-marie-tooth-disease-4d
#10
Bin Chen, Songtao Niu, Na Chen, Hua Pan, Xingao Wang, Zaiqiang Zhang
Charcot-Marie-Tooth disease 4D (CMT4D) is characterized by severe peripheral neuropathy and deafness. It is caused by mutations in the N-myc downstream-regulated gene 1 (NDRG1). We report a Chinese man with a homozygous mutation c.675C > T of NDRG1 that resulted in Q185X, representing the third known CMT4D patient of non-European ancestry. The patient presented with a 15-year-long history of progressive limb weakness accompanied by hearing loss and dysarthria. There was abnormal differentiation and increased interpeak latencies in brainstem auditory evoked potentials...
April 30, 2018: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/29719360/neuropsychiatric-symptoms-induced-by-large-doses-of-nitrous-oxide-inhalation-a-case-report
#11
Tianzhen Chen, Na Zhong, Haifeng Jiang, Min Zhao, Zhikang Chen, Haiming Sun
Nitrous Oxide, which is also called laughing gas, now ranks as the 7th most popular drug in the world. Nitrous oxide mainly disturbs B12 metabolism and damages nerves, followed by apparent neuropsychiatric symptoms. It's beneficial to the prognosis of patients if we identify and treat their symptoms early. This case report describes a 19-year-old male who presented with auditory hallucination, persecutory delusions and unstable emotions after abuse of nitrous oxide over the course of half a year. Moreover, neurological signs such as weakness and hyperesthesia also appeared...
February 25, 2018: Shanghai Archives of Psychiatry
https://www.readbyqxmd.com/read/29718280/early-communication-development-of-children-with-auditory-brainstem-implants
#12
Laurie S Eisenberg, Dianne Hammes Ganguly, Amy S Martinez, Laurel M Fisher, Margaret E Winter, Jamie L Glater, Debra K Schrader, Janice Loggins, Eric P Wilkinson
The auditory brainstem implant (ABI) is an auditory sensory device that is surgically placed on the cochlear nucleus of the brainstem for individuals who are deaf but unable to benefit from a cochlear implant (CI) due to anatomical abnormalities of the cochlea and/or eighth nerve, specific disease processes, or temporal bone fractures. In the United States, the Food and Drug Administration has authorized a Phase I clinical trial to determine safety and feasibility of the ABI in up to 10 eligible young children who are deaf and either derived no benefit from the CI or were anatomically unable to receive a CI...
April 26, 2018: Journal of Deaf Studies and Deaf Education
https://www.readbyqxmd.com/read/29717130/high-frequency-neural-spiking-and-auditory-signaling-by-ultrafast-red-shifted-optogenetics
#13
Thomas Mager, David Lopez de la Morena, Verena Senn, Johannes Schlotte, Anna D Errico, Katrin Feldbauer, Christian Wrobel, Sangyong Jung, Kai Bodensiek, Vladan Rankovic, Lorcan Browne, Antoine Huet, Josephine Jüttner, Phillip G Wood, Johannes J Letzkus, Tobias Moser, Ernst Bamberg
Optogenetics revolutionizes basic research in neuroscience and cell biology and bears potential for medical applications. We develop mutants leading to a unifying concept for the construction of various channelrhodopsins with fast closing kinetics. Due to different absorption maxima these channelrhodopsins allow fast neural photoactivation over the whole range of the visible spectrum. We focus our functional analysis on the fast-switching, red light-activated Chrimson variants, because red light has lower light scattering and marginal phototoxicity in tissues...
May 1, 2018: Nature Communications
https://www.readbyqxmd.com/read/29716282/click-reception-in-the-harbor-porpoise-phocoena-phocoena-effects-of-electrode-and-contact-transducer-location-on-the-auditory-brainstem-response
#14
Jason Mulsow, James J Finneran, Dorian S Houser, Chad A Nordstrom, Lance G Barrett-Lennard, Robert F Burkard
Unlike terrestrial mammals that have unambiguous aerial sound transmission pathways via the outer ear and tympanum, sound reception pathways in most odontocetes are not well understood. Recent studies have used auditory brainstem response (ABR) measurements to examine sound reception pathways. This study sought to determine how sound source placements, recording electrode arrangements, and ABR peak analyses affect interpretations of sound reception in the harbor porpoise (Phocoena phocoena). Click stimuli were delivered in air from a contact transducer ("jawphone")...
April 2018: Journal of the Acoustical Society of America
https://www.readbyqxmd.com/read/29716239/reduction-of-sound-evoked-midbrain-responses-observed-by-functional-magnetic-resonance-imaging-following-acute-acoustic-noise-exposure
#15
Bin Yang, Eddie Wong, Wai Hong Ho, Condon Lau, Ying Shing Chan, Ed X Wu
Short duration and high intensity acoustic exposures can lead to temporary hearing loss and auditory nerve degeneration. This study investigates central auditory system function following such acute exposures after hearing loss recedes. Adult rats were exposed to 100 dB sound pressure level noise for 15 min. Auditory brainstem responses (ABRs) were recorded with click sounds to check hearing thresholds. Functional magnetic resonance imaging (fMRI) was performed with tonal stimulation at 12 and 20 kHz to investigate central auditory changes...
April 2018: Journal of the Acoustical Society of America
https://www.readbyqxmd.com/read/29708489/fmri-as-a-preimplant-objective-tool-to-predict-children-s-postimplant-auditory-and-language-outcomes-as-measured-by-parental-observations
#16
Aniruddha K Deshpande, Lirong Tan, Long J Lu, Mekibib Altaye, Scott K Holland
BACKGROUND: The trends in cochlear implantation candidacy and benefit have changed rapidly in the last two decades. It is now widely accepted that early implantation leads to better postimplant outcomes. Although some generalizations can be made about postimplant auditory and language performance, neural mechanisms need to be studied to predict individual prognosis. PURPOSE: The aim of this study was to use functional magnetic resonance imaging (fMRI) to identify preimplant neuroimaging biomarkers that predict children's postimplant auditory and language outcomes as measured by parental observation/reports...
May 2018: Journal of the American Academy of Audiology
https://www.readbyqxmd.com/read/29705021/endoscope-assisted-decompression-of-facial-nerve-for-treatment-of-hemifacial-spasm
#17
J Magnan
Microvascular decompression has become the sole method for a curative treatment of primary hemifacial spasm. Finding the responsible conflicting artery is not always easy as its location can be deeply situated within the cerebellopontine/medullary fissure at the facial root exit zone. Sole or additional offending vessel(s) may be at the meatus of the internal auditory canal (5% of the cases). Identifying the compressive vessel(s) and performing decompression is in most cases possible without cerebellar retraction by classical microsurgical techniques...
April 25, 2018: Neuro-Chirurgie
https://www.readbyqxmd.com/read/29704694/flexible-endoscopic-assisted-microsurgical-radical-resection-of-intracanalicular-vestibular-schwannomas-by-retrosigmoid-approach-operative-technique
#18
Francesco Corrivetti, Guglielmo Cacciotti, Carlo Giacobbo Scavo, Raffaelino Roperto, Luciano Mastronardi
BACKGROUND: s: The efficacy of endoscopic techniques in the surgical management of intracanalicular vestibular schwannomas (ICVS) has been underlined in recent studies. Particularly, endoscopic assisted retrosigmoid approach (EARSA) appears particularly suitable in achieving complete resection of ICVS. OBJECTIVE: In this study we present the surgical treatment of 3 cases of ICVS, treated with an endoscopic assisted retrosigmoid approach, highlighting advantages and limitations of flexible endoscope in the accomplishment of a safe radical resection with hearing preservation...
April 25, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29698581/segmental-analysis-of-the-vestibular-nerve-and-the-efferents-of-the-vestibular-complex
#19
Carmen Díaz, Luis Puelles
Use of a segmental approach in the study of vestibular centers in the hindbrain improves morphological and functional understanding of this region controlled by Hox genes, among other molecular determinants. Here we review accrued data about segmental organization of vestibular afferents and efferents. Inner ear-originated vestibular fibers enter the hindbrain, together with auditory ones, through the alar plate of rhombomere 4, then branch into descending and ascending branches to reach appropriate vestibular nuclei along the vestibular column...
April 26, 2018: Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology
https://www.readbyqxmd.com/read/29686816/evaluation-of-the-prognostic-value-of-multimodal-intraoperative-monitoring-in-posterior-fossa-surgery-patients-with-cerebellopontine-angle-tumors
#20
Mohsen Dalvandi, Ali Nazemi Rafie, Alireza Kamali, Alireza Jamshidifard
The aim of this study was to compare the outcomes of four intraoperative monitoring approaches in order to compare their prognostic value in surgical complications of the facial nerve. This quasi-experimental study was conducted on 25 patients with Cerebellopontine Angle (CPA) tumors, who were hospitalized in the Valiasr Hospital, affiliated to the Arak University of Medical Sciences, Arak, Iran. The degree of the facial nerve paralysis was assessed based on the House-Brackmann (HB) facial nerve grading system...
January 12, 2018: European Journal of Translational Myology
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