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https://www.readbyqxmd.com/read/28738189/surgical-landmarks-to-locating-the-main-trunk-of-the-facial-nerve-in-parotid-surgery-a-systematic-review
#1
Yisi D Ji, R Bruce Donoff, Zachary S Peacock, Eric R Carlson
PURPOSE: The purpose of this study was to describe distances from commonly used anatomic landmarks to the main trunk of the facial nerve during parotid surgery. MATERIALS AND METHODS: A systematic search of the published literature was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. All studies from January 1, 1990 to January 1, 2017 that measured distances to the main trunk of the facial nerve from common anatomic landmarks were eligible...
June 30, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28729937/manganese-enhanced-magnetic-resonance-imaging-combined-with-electrophysiology-in-the-evaluation-of-visual-pathway-in-experimental-rat-models-with-monocular-blindness
#2
Zuohua Tang, Jie Wang, Zebin Xiao, Xinghuai Sun, Xiaoyuan Feng, Weijun Tang, Qian Chen, Lingjie Wu, Rong Wang, Yufeng Zhong, Wentao Wang, Jianfeng Luo
PURPOSE: Our study aimed to explore the feasibility of manganese-enhanced magnetic resonance imaging (MEMRI) combined with visual evoked potentials (VEP) and auditory evoked visual cortex responses (AVR) in evaluating for the establishment of visual/auditory compensatory pathways after monocular blindness. MATERIALS AND METHODS: A total of 14 healthy neonatal male Sprague-Dawley rats were randomly divided into two groups (n = 7 for Groups A and B). Right optic nerve (ON) transection was performed on the 7 rats of Group A to obtain a monocularly blind model, and the 7 rats of Group B were chosen as the control group...
July 2017: Brain and Behavior
https://www.readbyqxmd.com/read/28725513/facial-nerve-schwannomas-mimicking-as-vestibular-schwannomas
#3
Beth N McNulty, Sean Wise, David S Cohen, Jason Bell, Dennis Bojrab, Michael LaRouere, Matthew Kircher, Seilesh Babu
Objective  The objective of this study was to identify preoperative and intraoperative findings that may aid in distinguishing facial nerve schwannomas (FNS) from vestibular schwannomas (VSs), particularly in cases limited to the internal auditory canal (IAC) and cerebellopontine angle (CPA). Study Design  This was a retrospective study. Setting  This study was set at a Tertiary Referral Center. Patients  Seventeen cases from October 2002 to July 2015 with an IAC/CPA mass presumed to be a VS who were found to have a FNS intraoperatively...
August 2017: Journal of Neurological Surgery. Part B, Skull Base
https://www.readbyqxmd.com/read/28713816/effect-of-the-camelid-s-seminal-plasma-ovulation-inducing-factor-%C3%AE-ngf-a-kisspeptin-target-hypothesis
#4
REVIEW
Khalid El Allali, Najlae El Bousmaki, Hassan Ainani, Valérie Simonneaux
Female mammals are classified into spontaneous and induced ovulators based on the mechanism eliciting ovulation. Ovulation in spontaneous species (e.g., human, sheep, cattle, horse, pigs, and most rodents) occurs at regular intervals and depends upon the circulating estradiol. However, in induced ovulators (e.g., rabbits, ferrets, cats, and camelids), ovulation is associated with coitus. In the later, various factors have been proposed to trigger ovulation, including auditory, visual, olfactory, and mechanic stimuli...
2017: Frontiers in Veterinary Science
https://www.readbyqxmd.com/read/28712672/noise-induced-cochlear-synaptopathy-in-rhesus-monkeys-macaca-mulatta
#5
M D Valero, J A Burton, S N Hauser, T A Hackett, R Ramachandran, M C Liberman
Cochlear synaptopathy can result from various insults, including acoustic trauma, aging, ototoxicity, or chronic conductive hearing loss. For example, moderate noise exposure in mice can destroy up to ∼50% of synapses between auditory nerve fibers (ANFs) and inner hair cells (IHCs) without affecting outer hair cells (OHCs) or thresholds, because the synaptopathy occurs first in high-threshold ANFs. However, the fiber loss likely impairs temporal processing and hearing-in-noise, a classic complaint of those with sensorineural hearing loss...
July 8, 2017: Hearing Research
https://www.readbyqxmd.com/read/28708797/role-of-multislice-ct-imaging-in-predicting-the-visibility-of-the-round-window-in-pediatric-cochlear-implantation
#6
Yasser A Fouad, Ahmad Shaker Elaassar, Mohammad Waheed El-Anwar, Ebrahim Sabir, Ahmad Abdelhamid, Mai Ghonimy
BACKGROUND: High-resolution computed tomography (HRCT) magnifies the role of preoperative imaging for detailed inner and middle ear anatomical information and enhances more efforts for better dependent correlation and measurements of round window (RW). OBJECTIVE: To find an applicable way by HRCT imaging for the prediction of the visibility of the RW during cochlear implantation (CI) surgery. METHODS: Five radiologic measurements were performed on the axial HRCT and these measurements were correlated with the degree of RW visibility after performing posterior tympanotomy during CI surgery...
July 13, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28708635/the-management-of-pediatric-hearing-loss-caused-by-auditory-neuropathy-spectrum-disorder
#7
Nguyen S Pham
PURPOSE OF REVIEW: Auditory neuropathy spectrum disorder (ANSD) is a condition in which auditory testing reveals normal otoacoustic emissions, but auditory brainstem testing is abnormal or absent and speech discrimination is poor. This constellation of findings ostensibly suggests that the cochlea is healthy and an abnormality of conduction or processing of sound occurs along the nerve fibers. As more is learned about this condition, it is becoming clear that ANSD describes heterogeneous, distinct clinical entities that must be taken into account when devising treatment modalities...
July 13, 2017: Current Opinion in Otolaryngology & Head and Neck Surgery
https://www.readbyqxmd.com/read/28704898/a-case-of-auditory-neuropathy-caused-by-pontine-hemorrhage-in-an-adult
#8
Seung-Hyun Chung, Sung Wook Jeong, Lee-Suk Kim
A pontine hemorrhage can evoke several neurological symptoms because the pons contains various nuclei and nerve fibers. Hearing loss can develop as a result of a pontine hemorrhage because there is an auditory conduction pathway in the cochlear nucleus of the pons. However, very few cases of hearing loss caused by pontine lesions have been reported, and there have been no reports of auditory neuropathy that developed following a pontine hemorrhage. Recently we had a patient who experienced a nontraumatic pontine hemorrhage who was diagnosed with auditory neuropathy...
July 2017: Journal of Audiology & Otology
https://www.readbyqxmd.com/read/28701535/enhancement-of-phase-locking-in-rodents-i-an-axonal-recording-study-in-gerbil
#9
Liting Wei, Shotaro Karino, Eric Verschooten, Philip X Joris
The trapezoid body (TB) contains axons of neurons in the anteroventral cochlear nucleus (AVCN) projecting to monaural and binaural nuclei in the superior olivary complex (SOC). Characterization of these monaural inputs is important for the interpretation of response properties of SOC neurons. In particular, understanding of the sensitivity to interaural time differences (ITDs) in neurons of the medial and lateral superior olive (MSO and LSO) requires knowledge of the temporal firing properties of the monaural excitatory and inhibitory inputs to these neurons...
July 12, 2017: Journal of Neurophysiology
https://www.readbyqxmd.com/read/28700446/pure-tone-masking-patterns-for-monopolar-and-phantom-electrical-stimulation-in-cochlear-implants
#10
Aniket A Saoji, Kanthaiah Koka, Leonid M Litvak, Charles C Finley
OBJECTIVES: Monopolar stimulation of the most apical electrode produces the lowest pitch sensation in cochlear implants clinically. A phantom electrode that uses out-of-phase electrical stimulation between the most apical and the neighboring basal electrode can produce a lower pitch sensation than that associated with the most apical electrode. However, because of the absence of contacts beyond the apical tip of the array, the ability to assess the spread of electrical excitation associated with phantom stimulation is limited in the typical cochlear implant subject with no residual hearing...
July 11, 2017: Ear and Hearing
https://www.readbyqxmd.com/read/28690836/noise-induced-and-age-related-hearing-loss-%C3%A2-new-perspectives-and-potential-therapies
#11
REVIEW
M Charles Liberman
The classic view of sensorineural hearing loss has been that the primary damage targets are hair cells and that auditory nerve loss is typically secondary to hair cell degeneration. Recent work has challenged that view. In noise-induced hearing loss, exposures causing only reversible threshold shifts (and no hair cell loss) nevertheless cause permanent loss of >50% of the synaptic connections between hair cells and the auditory nerve. Similarly, in age-related hearing loss, degeneration of cochlear synapses precedes both hair cell loss and threshold elevation...
2017: F1000Research
https://www.readbyqxmd.com/read/28690494/the-electrically-evoked-compound-action-potential-from-laboratory-to-clinic
#12
REVIEW
Shuman He, Holly F B Teagle, Craig A Buchman
The electrically evoked compound action potential (eCAP) represents the synchronous firing of a population of electrically stimulated auditory nerve fibers. It can be directly recorded on a surgically exposed nerve trunk in animals or from an intra-cochlear electrode of a cochlear implant. In the past two decades, the eCAP has been widely recorded in both animals and clinical patient populations using different testing paradigms. This paper provides an overview of recording methodologies and response characteristics of the eCAP, as well as its potential applications in research and clinical situations...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28688553/clinical-role-of-electrocochleography-in-children-with-auditory-neuropathy-spectrum-disorder
#13
Tatyana E Fontenot, Christopher K Giardina, Holly F Teagle, Lisa R Park, Oliver F Adunka, Craig A Buchman, Kevin D Brown, Douglas C Fitzpatrick
OBJECTIVES: To assess electrocochleography (ECochG) to tones as an instrument to account for CI speech perception outcomes in children with auditory neuropathy spectrum disorder (ANSD). MATERIALS & METHODS: Children (<18 years) receiving CIs for ANSD (n = 30) and non-ANSD (n = 74) etiologies of hearing loss were evaluated with ECochG using tone bursts (0.25-4 kHz). The total response (TR) is the sum of spectral peaks of responses across frequencies. The compound action potential (CAP) and the auditory nerve neurophonic (ANN) in ECochG waveforms were used to estimate nerve activity and calculate nerve score...
August 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/28687782/human-cochlear-histopathology-reflects-clinical-signatures-of-primary-neural-degeneration
#14
Jessica E Sagers, Lukas D Landegger, Steven Worthington, Joseph B Nadol, Konstantina M Stankovic
Auditory neuropathy is a significant and understudied cause of human hearing loss, diagnosed in patients who demonstrate abnormal function of the cochlear nerve despite typical function of sensory cells. Because the human inner ear cannot be visualized during life, histopathological analysis of autopsy specimens is critical to understanding the cellular mechanisms underlying this pathology. Here we present statistical models of severe primary neuronal degeneration and its relationship to pure tone audiometric thresholds and word recognition scores in comparison to age-matched control patients, spanning every decade of life...
July 7, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28675079/cochlear-nerve-aplasia-and-hypoplasia-predictors-of-cochlear-implant-success
#15
Kevin A Peng, Edward C Kuan, Suzannah Hagan, Eric P Wilkinson, Mia E Miller
Objective To identify factors predicting performance outcomes following cochlear implantation in patients with cochlear nerve aplasia or hypoplasia. Data Sources Individual patient data extracted from published case series and reports. Review Methods The MEDLINE database, Cochrane Library, Embase, Web of Science, and Google Scholar were queried for "cochlear implant" in conjunction with "aplasia" or "hypoplasia" between 1985 and 2015. Eighteen studies were included describing 97 subjects with individual postimplant auditory data...
July 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28672008/nanofibrous-scaffolds-for-the-guidance-of-stem-cell-derived-neurons-for-auditory-nerve-regeneration
#16
Sandra Hackelberg, Samuel J Tuck, Long He, Arjun Rastogi, Christina White, Liqian Liu, Diane M Prieskorn, Ryan J Miller, Che Chan, Benjamin R Loomis, Joseph M Corey, Josef M Miller, R Keith Duncan
Impairment of spiral ganglion neurons (SGNs) of the auditory nerve is a major cause for hearing loss occurring independently or in addition to sensory hair cell damage. Unfortunately, mammalian SGNs lack the potential for autonomous regeneration. Stem cell based therapy is a promising approach for auditory nerve regeneration, but proper integration of exogenous cells into the auditory circuit remains a fundamental challenge. Here, we present novel nanofibrous scaffolds designed to guide the integration of human stem cell-derived neurons in the internal auditory meatus (IAM), the foramen allowing passage of the spiral ganglion to the auditory brainstem...
2017: PloS One
https://www.readbyqxmd.com/read/28659280/a-test-of-the-stereausis-hypothesis-for-sound-localization-in-mammals
#17
Andrius Plauška, Marcel van der Heijden, J Gerard G Borst
The relative arrival times of sounds at both ears constitute an important cue for localization of low-frequency sounds in the horizontal plane. The binaural neurons of the medial superior olive (MSO) act as coincidence detectors that fire when inputs from both ears arrive near simultaneously. Each principal neuron in the MSO is tuned to its own best interaural time difference (ITD), indicating the presence of an internal delay, a difference in the travel times from either ear to the MSO. According to the stereausis hypothesis, differences in wave propagation along the cochlea could provide the delays necessary for coincidence detection if the ipsi- and contralateral inputs originated from different cochlear positions, with different frequency tuning...
June 28, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28657954/outcomes-and-time-to-emergence-of-auditory-skills-after-cochlear-implantation-of-children-with-charge-syndrome
#18
Nancy M Young, Elizabeth Tournis, Jenelle Sandy, Stephen R Hoff, Maura Ryan
OBJECTIVE: Review perioperative complications, benefits, and the timeframe over which auditory skills develop in children with CHARGE syndrome who receive a cochlear implant (CI). STUDY DESIGN: IRB-approved retrospective chart review of children with CHARGE syndrome who had at least 12 months of cochlear implant use. SETTING: Tertiary care children's hospital. PATIENTS: Twelve children, seven males and five females. Mean age implant = 3...
June 27, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28650602/intraoperative-neurophysiological-monitoring-to-protect-the-facial-nerve-during-microsurgery-for-large-vestibular-schwannomas
#19
(no author information available yet)
OBJECTIVE: Microsurgery is the preferred treatment for large vestibular schwannomas (VSs). However, anatomical and functional preservation of the facial nerve (FN) remains a challenge during this surgery. The aim of this study was to determine whether it is beneficial to the preservation rates of the FN during microsurgical treatment of large VSs using intraoperative neurophysiological monitoring (IONM). METHODS: We retrospectively reviewed 53 patients with large VSs that underwent microsurgical resection via the retrosigmoid approach in our department during April 2009 to March 2016...
May 26, 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/28636731/correlation-among-external-auditory-canal-anomaly-temporal-bone-malformation-and-hearing-levels-in-patients-with-microtia
#20
Kun Chen, Liu Liu, Runjie Shi, Peihua Wang, Dong Chen, Hua Xiao
We conducted a retrospective study to evaluate the relationship between external auditory canal (EAC) anomaly, temporal bone abnormality, and hearing levels using objective scoring systems in Chinese patients with microtia. The study population consisted of 106 ears of 94 Chinese patients (67 male and 27 female) aged 5 to 45 years (mean: 12.6) with microtia. The EAC abnormalities were classified into 4 types according to Schuknecht's criteria: type A, type B, type C, and type D. Developmental anomalies of the temporal bone were evaluated by Jahrsdoerfer computed tomography (CT) scoring system using high-resolution CT scans of the temporal bone...
June 2017: Ear, Nose, & Throat Journal
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