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Cannabis arteritis

Grace Thomas, Robert A Kloner, Shereif Rezkalla
Marijuana is the most widely used illicit drug, with approximately 200 million users worldwide. Once illegal throughout the United States, cannabis is now legal for medicinal purposes in several states and for recreational use in 3 states. The current wave of decriminalization may lead to more widespread use, and it is important that cardiologists be made aware of the potential for marijuana-associated adverse cardiovascular effects that may begin to occur in the population at a greater frequency. In this report, the investigators focus on the known cardiovascular, cerebrovascular, and peripheral effects of marijuana inhalation...
January 1, 2014: American Journal of Cardiology
T Hermanns-Lé, P Delvenne, G E Piérard, A F Rousseau, C Piérard-franchimont
Marijuana, cannabis, hemp designate some plants and their extracts enriched in cannabinoids including change 9-tetrahydrocannabinol (THC). This soft drug exerts psychoactive effects and is responsible for adverse events appearing on the skin, mucosae and eyes. Contact allergic urticaria possibly occurs as well as Raynaud's phenomenon and arteritis resembling Buerger's disease. Glossitis and atrophic stomatitis may be associated with paronditis and uvular angioedema.
May 2013: Revue Médicale de Liège
Anne Claire Desbois, Patrice Cacoub
BACKGROUND: The aim of this study was to describe the different arterial complications reported in cannabis smokers. METHODS: This study was a literature review. RESULTS: Cannabis use was found to be associated with stroke, myocardial infarction, and lower limb arteritis. Arterial disease involved especially young men. There was a very strong temporal link between arterial complications and cannabis use for stroke and myocardial infarction episodes...
October 2013: Annals of Vascular Surgery
Olivier Cottencin, Laurent Karila, Marc Lambert, Catherine Arveiller, Amine Benyamina, Alain Boissonas, Michel Goudemand, Michel Reynaud
Consumption of cannabis in young adults has continued to increase in recent years. Cannabis arteritis was first described in the 1960s, but the number of cases has continued to increase. We reviewed current knowledge of the different types of cannabis arteritis in young adults and found 70 cases of cannabis arteritis in the literature. We discuss physiopathological arguments in favor of cannabis vascular toxicity per se, although we did not find sufficient evidence to identify cannabis arteritis as a specific diagnostic entity...
December 2010: Journal of Addiction Medicine
Guillaume Martin-Blondel, Fabien Koskas, Patrice Cacoub, Damien Sène
BACKGROUND: Cannabis implication in the pathophysiology of distal arteritis remains controversial. The aim is to assess whether cannabis co-exposure influences presentation and outcome of thromboangiitis obliterans (TAO) in tobacco smokers. METHODS: All consecutive patients presenting with a definite TAO were retrospectively reviewed according to their tobacco and cannabis consumption status. RESULTS: A total of 38 patients with a definite TAO were included in this study...
May 2011: Annals of Vascular Surgery
Dominique Tennstedt, Anaïs Saint-Remy
From time out of mind, man has grown hemp for both "industrial" and "recreational" use (it is then referred to as cannabis). Of course, cannabis has strong psychoactive properties and is one of the most commonly used "soft drugs" in the world. Clinicians should know the adverse effects on mucous membranes and on skin, which may sometimes entail an absolutely necessary stopping of consumption. Raynaud's phenomenon, as well as arteritis due to cannabis consumption may be extremely severe and result in worrying situations for both clinicians and patients...
January 2011: European Journal of Dermatology: EJD
Sally Daganzo, George Nune
No abstract text is available yet for this article.
September 2010: Journal of Hospital Medicine: An Official Publication of the Society of Hospital Medicine
F Grotenhermen
BACKGROUND: To investigate the hypothesis that cases of arteritis similar to thromboangiitis obliterans (TAO) and associated with the use of cannabis were caused by cannabis or THC (dronabinol), or that cannabis use is a co-factor of TAO. PATIENTS AND METHODS: A systematic review on case reports and the literature on so-called cannabis arteritis, TAO, and cardiovascular effects of cannabinoids was conducted. RESULTS: Fifteen reports with 57 cases of an arteritis associated with the use of cannabis and two additional case series of TAO, in which some patients also used cannabis, were identified...
February 2010: VASA. Zeitschrift Für Gefässkrankheiten
Bernard Noël, Isabelle Ruf, Renato G Panizzon
Cannabis arteritis is a serious peripheral vascular disease affecting young adults consuming cannabis. An increasing number of cases have been recently reported in Europe. The risk of amputation is high. Cannabis arteritis is often confused with atherosclerosis. We present a new case in which complete arterial revascularization was obtained with early aspirin treatment. Cannabis arteritis should be therefore distinguished from peripheral arterial disease caused by atherosclerosis, which is typically not reversible...
May 2008: Journal of the American Academy of Dermatology
I Peyrot, A-M Garsaud, I Saint-Cyr, O Quitman, B Sanchez, D Quist
Cannabis arteritis manifests in cannabis users, independently of tobacco consumption. Around 50 cases were reported in the literature since the first description of this entity in 1960. We report the case of a 36-year-old man, cannabis user, without vascular risk factor who developed digital necrosis on the right foot. The pedal pulses were not palpable. He had no abnormal laboratory findings. Arteriography revealed distal segmental lesions and occlusion of popliteal artery. This arteritis was linked to cannabis use, but the patient did not stop cannabis consumption...
March 2007: Journal of the European Academy of Dermatology and Venereology: JEADV
Michel Mallaret, Dominique Dal'Bo-Rohrer, Maurice Demattéis
When admitted in an emergency unit, young patients often present acute neurological effects of smoked marijuana. Other chronic adverse effects of marijuana are probably underestimated: postural syncope, arteritis, chronic bronchitis, amnesia. Marijuana may trigger a myocardial infarction and have a vasospastic effect. Marijuana has impairing effects on driving ability. Smoked marijuana is a potential respiratory tract carcinogen.
January 15, 2005: La Revue du Praticien
Boris Leithäuser, Alexander C Langheinrich, Wigbert S Rau, Harald Tillmanns, F Reinhard Matthias
This case report describes a 22-year-old woman with severe arterial ischemia leading to claudication and ulceration of the feet, presumably due to long-term abuse of amphetamine derivates, such as "speed" or "ecstasy," and cannabis. Known causes for peripheral occlusive disease, such as atherosclerosis, vasculitis, or collagen vascular disease, were excluded. Laboratory test results did not show evidence of risk factors for thromboembolic diseases. Conventional angiography and magnetic resonance-angiography showed occlusions of medium- and small-sized arteries of both calves and feet...
February 2005: Heart and Vessels
P Combemale, T Consort, L Denis-Thelis, J-L Estival, M Dupin, J Kanitakis
The main causes of arteriopathy in young patients include drugs, metabolic diseases, pseudoxanthoma elasticum and Buerger's disease. Arteritis due to Cannabis indica was first reported in 1960, and the role of this drug as a risk factor for arteritis was confirmed in several subsequent publications. A 38-year-old smoker with no previous contributory medical history except for long-standing cannabis abuse developed a dry necrotic lesion of the left big toe. Imaging examinations revealed proximal arteriopathy of the lower limbs that predominated on the left side...
January 2005: British Journal of Dermatology
Laurent Karila, T Danel, Sarah Coscas, J P Chambon, M Reynaud
INTRODUCTION: Since the end of the nineteen-nineties, cannabis is not only incriminated in the onset of thromboangiitis obliterans but also in inducing artheromatous lesions in young subjects. OBSERVATION: A young, Caucasian, 18 year-old man was referred for cannabis withdrawal in the treatment of arteritis of the left leg. DISCUSSION: Cannabis is by far the illicite psychoactive substance most consumed by the 15-25 year-olds. Data in the literature, notably since the end of the nineteen-nineties, show that cannabis is accused of provoking arterial disease similar to that which is found in Buerger's disease (or thromboangiitis obliterans) in young subjects of whichever sex...
October 23, 2004: La Presse Médicale
E Ducasse, J Chevalier, D Dasnoy, F Speziale, P Fiorani, P Puppinck
OBJECTIVE: To report popliteal artery entrapment in a patient with distal necrosis and cannabis-related arteritis, two rare or exceptional disorders never described in association. To conduct a targeted review and especially to seek information on the clinical presentation with characteristics specific to each disorder so as to hasten the diagnosis and choose appropriate management. MATERIAL AND METHODS: A 19-year-old man who presented with plantar claudication associated with necrosis in a toe underwent diagnostic arteriography and surgery for popliteal artery entrapment type III...
March 2004: European Journal of Vascular and Endovascular Surgery
No abstract text is available yet for this article.
February 1960: Archives des Maladies du Coeur et des Vaisseaux
A Gröger, A Aslani, T Wolter, E M Noah, N Pallua
A 24-year old woman, heavy cannabis smoker with progressive Raynauld's phenomenon and digital necrosis is presented. Systemic sclerosis and other connective tissue disorders as well as arteriosclerosis and arterial emboli were excluded with appropriate laboratory examinations. Arteriography revealed multiple forearm, palmar and digital occlusions with corkscrew-shaped vessels. Based on these characteristic arteriography and clinical findings, the diagnosis of cannabis-arteritis was finally retained. With careful necrectomy, conservative wound dressings and secondary prostacyclin therapy a complete healing of digital necrosis was observed...
May 2003: VASA. Zeitschrift Für Gefässkrankheiten
C Cazalets, E Laurat, B Cador, F Jan, Y Rolland, P Jégo, B Grosbois
INTRODUCTION: The responsibility of cannabis in juvenile thromboangeitis has been suggested for few years. We describe four new cases. EXEGESIS: Young men presented with distal arteriopathy of the lower limbs in 3 cases, and of the left upper limb in the remaining patient. Symptoms occurred progressively, distal pulses had disappeared, and distal necrosis was constant. Three patients suffered from Raynaud phenomenon, none of them presented with venous thrombosis...
February 2003: La Revue de Médecine Interne
P Disdier, B Granel, J Serratrice, J Constans, U Michon-Pasturel, E Hachulla, C Conri, B Devulder, L Swiader, P Piquet, A Branchereau, J Jouglard, G Moulin, P J Weiller
The purpose of this paper was to revisit the old concept of cannabis arteritis first described in the 1960s and report 10 new cases. Ten male patients, with a median age of 23.7 years developed subacute distal ischemia of lower or upper limbs, leading to necrosis in the toes and/or fingers and sometimes to distal limb gangrene. Two of the patients also presented with venous thrombosis and three patients were suffering from a recent Raynaud's phenomenon. Biological test results did not show evidence of the classical vascular risk factors for thrombosis...
January 2001: Angiology
F Schneider, N Abdoucheli-Baudot, M Tassart, F Boudghène, P Gouny
The causal effect of cannabis, associated or not with smoking, in juvenile thromboangiitis disorders such as Leo Buerger disease, has been suggested. We describe here a case of a 30-year-old woman who smoked cannabis and developed intermittent claudication of the lower limbs. Female sex and proximal localization of the lesions (external iliac artery) are not usually described in "cannabis arteritis". Cannabis would be involved not only in the pathogenesis of juvenile obstructive arteriopathy, but also in the development of atheromatous lesions in the young subject...
December 2000: Journal des Maladies Vasculaires
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