Göran Starck, Maria Ljungberg, Marie Nilsson, Lars Jönsson, Stefan Lundberg, Tord Ivarsson, Susanne Ribbelin, Sven Ekholm, Arvid Carlsson, Eva Forssell-Aronsson, Maria L Carlsson
1H magnetic resonance spectroscopy (1H MRS) studies exploring brain metabolites, especially glutamine + glutamate (Glx), in obsessive compulsive disorder (OCD) are of vital interest for trying to understand more about the pathophysiology of OCD. Therefore, we conducted the present 1H MRS study with the aims of (1) comparing MRS metabolites in a group of adult patients with OCD and a group of healthy controls, and (2) examining the relationship between MRS metabolite concentrations and symptom severity in the patient group...
July 2008: Journal of Neural Transmission