keyword
MENU ▼
Read by QxMD icon Read
search

MM Babu

keyword
https://www.readbyqxmd.com/read/28360469/myelomatous-pleural-effusion-a-rare-case-entity-reported-from-a-tertiary-care-cancer-center-in-south-india
#1
Govind K Babu, Smitha C Saldanha, K N Lokesh, M C Suresh Babu, Akkamaha Devi Patil, Pretesh R Kiran, K C Lakshmaiah, D Lokanatha
Multiple myeloma (MM) is a plasma cell neoplasm and constitutes 10% of hematologic malignancies. Malignant myelomatous pleural effusions are very rare and occur in <1% of cases of MM. In this article, we report a rare case of a patient who initially presented with pleural effusion and was subsequently found to be secondary to MM with an underlying raised IgG paraprotein. The patient symptomatically improved and was in partial remission with palliative radiotherapy, VTD chemotherapy, and bisphosphonates.
March 2017: Lung India: Official Organ of Indian Chest Society
https://www.readbyqxmd.com/read/28351708/biochemical-and-inhibition-studies-of-glutamine-synthetase-from-leishmania-donovani
#2
Vinay Kumar, Shailendra Yadav, Neelagiri Soumya, Rohit Kumar, Neerupudi Kishore Babu, Sushma Singh
Leishmaniasis is a group of tropical diseases caused by protozoan parasites of the genus Leishmania. Leishmania donovani is a protozoan parasite that causes visceral leishmaniasis, a fatal disease if left untreated. Chemotherapy for leishmaniasis is problematic as the available drugs are toxic, costly and shows drug resistance, hence, there is a necessity to look out for the novel drug targets, chemical entities and vaccine. Glutamine synthetase (GS) catalyzes the synthesis of glutamine from glutamate and ammonia...
March 25, 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/28299407/design-and-development-of-acetylthiocholine-electrochemical-biosensor-based-on-zinc-oxide-cerium-oxide-nanohybrid-modified-platinum-electrode
#3
Manju Bhargavi Gumpu, Noel Nesakumar, Srinidhi Nagarajan, Sadhana Ramanujam, Uma Maheswari Krishnan, K Jayanth Babu, John Bosco Balaguru Rayappan
Acetylcholinesterase (AChE) enzyme has been predominantly used for the detection of pesticides and metal ions. But, these sensors respond to pesticides as well as metal ions at certain concentration, which results in poor selectivity. Hence in this work, the amount of thiocholine produced during AChE inhibition has been estimated to detect the residual activity of AChE enzyme in-turn to enhance the efficiency of the biosensor. In this context, Pt/ZnO-CeO2/AChE/Chitosan based biosensor has been developed for sensitive voltammetric quantification of thiocholine in AChE...
March 16, 2017: Bulletin of Environmental Contamination and Toxicology
https://www.readbyqxmd.com/read/28270427/contemporary-cardiac-surgery-for-adults-with-congenital-heart-disease
#4
Sylvain Beurtheret, Oktay Tutarel, Gerhard Paul Diller, Cathy West, Evangelia Ntalarizou, Noémie Resseguier, Vasileios Papaioannou, Richard Jabbour, Victoria Simpkin, Anthony J Bastin, Sonya V Babu-Narayan, Beatrice Bonello, Wei Li, Babulal Sethia, Hideki Uemura, Michael A Gatzoulis, Darryl Shore
OBJECTIVE: Advances in early management of congenital heart disease (CHD) have led to an exponential growth in adults with CHD (ACHD). Many of these patients require cardiac surgery. This study sought to examine outcome and its predictors for ACHD cardiac surgery. METHODS: This is an observational cohort study of prospectively collected data on 1090 consecutive adult patients with CHD, undergoing 1130 cardiac operations for CHD at the Royal Brompton Hospital between 2002 and 2011...
March 7, 2017: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/28228725/differential-effects-of-corm-2-and-corm-401-in-murine-intestinal-epithelial-mode-k-cells-under-oxidative-stress
#5
Dinesh Babu, Georges Leclercq, Roberto Motterlini, Romain A Lefebvre
Carbon monoxide (CO)-releasing molecules (CO-RMs) are intensively studied to provide cytoprotective and anti-inflammatory effects of CO in inflammatory conditions including intestinal inflammation. The water-soluble CORM-A1 reduced apoptosis and NADPH oxidase (NOX)-derived reactive oxygen species (ROS) induced by tumor necrosis factor (TNF)-α/cycloheximide (CHX) in mouse MODE-K intestinal epithelial cells (IECs), without influencing TNF-α/CHX-induced mitochondrial superoxide anion ([Formula: see text]). The aim of the present study in the same model was to comparatively investigate the influence of lipid-soluble CORM-2 and water-soluble CORM-401, shown in vitro to release more CO under oxidative conditions...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/28218604/everolimus-eluting-bioresorbable-vascular-scaffold-for-treatment-of-complex-chronic-total-occlusions
#6
Jiang Ming Fam, Soledad Ojeda, Roberto Garbo, Azeem Latib, Alessio La Manna, Beatriz Vaquerizo, Marouane Boukhris, Georgios J Vlachojannis, Robert Jan van Geuns, Babu Ezhumalai, Hiroyoshi Kawamoto, Jors van der Sijde, Cordula Felix, Manuel Pan, Roberta Serdoz, Giacomo Giovanni Boccuzzi, Marcella De Paolis, Gennaro Sardella, Corrado Tamburino, Pieter C Smits, Carlo Di Mario, Ashok Seth, Antonio Serra, Antonio Colombo, Patrick Serruys, Alfredo R Galassi, Felix Zijlstra, Nicolas M van Mieghem, Roberto Diletti
AIMS: Bioresorbable vascular scaffolds (BVS) represent a novel therapeutic option for the treatment of coronary artery diseases. The objective of this study is to evaluate the feasibility of BVS implantation in complex chronic total occlusions (CTO). METHODS AND RESULTS: The present report is a multi-centre registry evaluating results after BVS deployment in challenging CTO lesions defined as J-CTO score≥2 (difficult or very difficult). A total of 105 patients were included in the present analysis...
February 21, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28105955/small-rna-profiles-in-soybean-primary-root-tips-under-water-deficit
#7
Yun Zheng, Vandana Hivrale, Xiaotuo Zhang, Babu Valliyodan, Christine Lelandais-Brière, Andrew D Farmer, Gregory D May, Martin Crespi, Henry T Nguyen, Ramanjulu Sunkar
BACKGROUND: Soybean (Glycine max) production is significantly hampered by frequent droughts in many regions of the world including the United States. Identifying microRNA (miRNA)-controlled posttranscriptional gene regulation under drought will enhance our understanding of molecular basis of drought tolerance in this important cash crop. Indeed, miRNA profiles in soybean exposed to drought were studied but not from the primary root tips, which is not only a main zone of water uptake but also critical for water stress sensing and signaling...
December 5, 2016: BMC Systems Biology
https://www.readbyqxmd.com/read/28088018/antibacterial-serine-protease-from-wrightia-tinctoria-purification-and-characterization
#8
Sakthivel Muthu, Venkatesh Babu Gopal, Selvakumar Soundararajan, Karthikeyan Nattarayan, Karthik S Narayan, Mythileeswari Lakshmikanthan, Sathuvan Malairaj, Palani Perumal
A serine protease was purified from the leaves of Wrightia tinctoria by sequential flow through method comprising screening, optimization, ammonium sulfate precipitation, gel filtration and ion exchange column chromatography. The yield and purification fold obtained were 11.58% and 9.56 respectively. A single band of serine protease was visualized on SDS-PAGE and 2-D gel electrophoretic analyses were revealed with the molecular mass of 38.5 kDa. Serine protease had an optimum pH of 8.0 and was stable at 45°C with high relative protease activity...
January 3, 2017: Plant Physiology and Biochemistry: PPB
https://www.readbyqxmd.com/read/27833123/ni-co-bimetal-nanowires-filled-multiwalled-carbon-nanotubes-for-the-highly-sensitive-and-selective-non-enzymatic-glucose-sensor-applications
#9
K Ramachandran, T Raj Kumar, K Justice Babu, G Gnana Kumar
The facile, time and cost efficient and environmental benign approach has been developed for the preparation of Nickel (Ni)-Cobalt (Co) alloy nanowires filled multiwalled carbon nanotubes (MWCNTs) with the aid of mesoporous silica nanoparticles (MSN)/Ni-Co catalyst. The controlled incorporation of Ni-Co nanostructures in the three dimensional (3D) pore structures of MSN yielded the catalytically active system for the MWCNT growth. The inner surface of MWCNTs was quasi-continuously filled with face-centered cubic (fcc) structured Ni-Co nanowires...
November 11, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27704184/mini-percutaneous-nephrolithotomy-for-stones-in-anomalous-kidneys-a-prospective-study
#10
Sanjay Khadgi, Babu Shrestha, Hamdy Ibrahim, Sunil Shrestha, Mohammed S ElSheemy, Ahmed M Al-Kandari
To evaluate safety and efficacy of minipercutaneous nephrolithotomy (Mini-PNL) in management of stones in different types of renal anomalies. Patients with stones ≥2 cm or SWL-resistant stones in anomalous-kidneys treated by Mini-PNL between March 2010 and September 2012 were included prospectively. Mini-PNL was done under regional anesthesia in prone position with fluoroscopic guidance through 18 Fr sheath using semirigid ureteroscope (8.5/11.5 Fr) and pneumatic lithotripter. All patients were followed-up for 2-3 years...
October 4, 2016: Urolithiasis
https://www.readbyqxmd.com/read/27636391/incidence-of-pediatric-superior-semicircular-canal-dehiscence-and-inner-ear-anomalies-a-large-multicenter-review
#11
Eric M Sugihara, Seilesh C Babu, Dennis J Kitsko, Michael S Haupert, Prasad J Thottam
OBJECTIVE: To determine the pediatric incidence and association of superior semicircular canal dehiscence (SSCD) with inner ear (IE) anomalies. STUDY DESIGN: Retrospective chart review. SETTING: Two tertiary referral centers. PATIENTS: Children less than 18 years who received a 0.5 mm or less collimated computed tomography study including the temporal bones between 2010 and 2013 for reasons including, but not limited to, hearing loss, trauma, and infection...
October 2016: Otology & Neurotology
https://www.readbyqxmd.com/read/27578931/role-of-computer-aided-diagnosis-cad-in-the-detection-of-pulmonary-nodules-on-64-row-multi-detector-computed-tomography
#12
K Prakashini, Satish Babu, K V Rajgopal, K Raja Kokila
AIMS AND OBJECTIVES: To determine the overall performance of an existing CAD algorithm with thin-section computed tomography (CT) in the detection of pulmonary nodules and to evaluate detection sensitivity at a varying range of nodule density, size, and location. MATERIALS AND METHODS: A cross-sectional prospective study was conducted on 20 patients with 322 suspected nodules who underwent diagnostic chest imaging using 64-row multi-detector CT. The examinations were evaluated on reconstructed images of 1...
July 2016: Lung India: Official Organ of Indian Chest Society
https://www.readbyqxmd.com/read/27465143/%C3%AE-carboxyethyl-hydroxychroman-a-metabolite-of-%C3%AE-tocopherol-preserves-nitric-oxide-bioavailability-in-endothelial-cells-challenged-with-high-glucose
#13
Youyou Li, Leena P Bharath, Ying Qian, Ting Ruan, Pon Velayutham Anandh Babu, Richard S Bruno, J David Symons, Thunder Jalili
Endothelial dysfunction occurs when there are imbalances between factors that regulate the synthesis and degradation of nitric oxide (NO(•)), and has been reported in patients with hyperglycemia and insulin resistance. We reported that supplementation with γ-tocopherol (γ-T) in humans limits impairments in endothelial function otherwise induced by postprandial hyperglycemia. Given the rapid metabolism of γ-T into γ-carboxyethyl hydroxychroman (γ-CEHC), we hypothesized that the vasoprotective activities of γ-T could be attributed to its metabolite γ-CEHC...
July 27, 2016: Experimental Biology and Medicine
https://www.readbyqxmd.com/read/27401084/in-patients-with-resectable-non-small-cell-lung-cancer-is-video-assisted-thoracoscopic-segmentectomy-an-appropriate-alternative-to-video-assisted-thoracoscopic-lobectomy
#14
Johnathan R Lex, Babu Naidu
A best evidence topic in thoracic surgery was written according to a structured protocol. The question addressed was 'In patients with resectable non-small-cell lung cancer, is video-assisted thoracoscopic segmentectomy an appropriate alternative to video-assisted thoracoscopic lobectomy?' Two hundred papers were found using the reported search, of which 8 represented the best evidence to answer the clinical question. The authors, journal, date and country of publication, patient group studied, study type, relevant outcomes and results of these papers are tabulated...
November 2016: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/27399395/115%C3%A2-the-southwestern-aneurysm-scoring-index-prediction-of-outcomes-at-1-year-in-ruptured-aneurysms-treated-with-microsurgery
#15
Vin Shen Ban, Jeffrey S Beecher, Christopher S Eddleman, Salah G Aoun, Kristopher Allen Lyon, Tarek Youssef El Ahmadieh, Cameron Michael McDougall, Babu Guai Welch, Joan Reisch, H Hunt Batjer, Duke S Samson, Jonathan A White
INTRODUCTION: Predicting outcome after aneurysmal rupture can be challenging. The Southwestern Aneurysm Severity Index (SASI) was developed to aid aneurysm treatment outcome prediction. In this introduction of SASI, we analyzed patients with ruptured aneurysms treated microsurgically. With the use of this cohort, each SASI element was evaluated to measure its value to the overall index. METHODS: Patients presenting to our institution with ruptured aneurysms from 2000 to 2014 treated with microsurgery were included...
August 2016: Neurosurgery
https://www.readbyqxmd.com/read/27164870/osteogenic-efficacy-of-strontium-hydroxyapatite-micro-granules-in-osteoporotic-rat-model
#16
Sunitha Chandran, Suresh Babu S, Hari Krishnan Vs, H K Varma, Annie John
Excessive demineralization in osteoporotic bones impairs its self-regeneration potential following a defect/fracture and is of great concern among the aged population. In this context, implants with inherent osteogenic ability loaded with therapeutic ions like Strontium (Sr(2+)) may bring forth promising outcomes. Micro-granular Strontium incorporated Hydroxyapatite scaffolds have been synthesized and in vivo osteogenic efficacy was evaluated in a long-term osteoporosis-induced aged (LOA) rat model. Micro-granules with improved surface area are anticipated to resorb faster and together with the inherent bioactive properties of Hydroxyapatite with the leaching of Strontium ions from the scaffold, osteoporotic bone healing may be promoted...
May 9, 2016: Journal of Biomaterials Applications
https://www.readbyqxmd.com/read/27110496/novel-precise-accurate-ion-pairing-method-to-determine-the-related-substances-of-the-fondaparinux-sodium-drug-substance-low-molecular-weight-heparin
#17
Amol A Deshpande, P Madhavan, Girish R Deshpande, Ravi Kumar Chandel, Kaviraj M Yarbagi, Alok R Joshi, J Moses Babu, R Murali Krishna, I M Rao
Fondaparinux sodium is a synthetic low-molecular-weight heparin (LMWH). This medication is an anticoagulant or a blood thinner, prescribed for the treatment of pulmonary embolism and prevention and treatment of deep vein thrombosis. Its determination in the presence of related impurities was studied and validated by a novel ion-pair HPLC method. The separation of the drug and its degradation products was achieved with the polymer-based PLRPs column (250 mm × 4.6 mm; 5 μm) in gradient elution mode. The mixture of 100 mM n-hexylamine and 100 mM acetic acid in water was used as buffer solution...
January 2016: Scientia Pharmaceutica
https://www.readbyqxmd.com/read/27092504/intra-tissue-pressure-measurement-in-ex-vivo-liver-undergoing-laser-ablation-with-fiber-optic-fabry-perot-probe
#18
Daniele Tosi, Paola Saccomandi, Emiliano Schena, Dinesh Babu Duraibabu, Sven Poeggel, Gabriel Leen, Elfed Lewis
We report the first-ever intra-tissue pressure measurement performed during 1064 nm laser ablation (LA) of an ex vivo porcine liver. Pressure detection has been performed with a biocompatible, all-glass, temperature-insensitive Extrinsic Fabry-Perot Interferometry (EFPI) miniature probe; the proposed methodology mimics in-vivo treatment. Four experiments have been performed, positioning the probe at different positions from the laser applicator tip (from 0.5 mm to 5 mm). Pressure levels increase during ablation time, and decrease with distance from applicator tip: the recorded peak parenchymal pressure levels range from 1...
April 15, 2016: Sensors
https://www.readbyqxmd.com/read/27048644/development-and-validation-of-an-lc-ms-ms-method-for-the-simultaneous-determination-of-simvastatin-simvastatin-acid-and-ezetimibe-in-human-plasma-and-its-application-to-pharmacokinetic-study-in-the-indian-population
#19
Sathish Babu Munaga, Rajani Kumar Valluru, Phani Bhushana Reddy Bonga, V Sumathi Rao, Hemanth Kumar Sharma
A simple, selective, sensitive and high-throughput liquid chromatography-tandem mass spectrometry (LC-MS-MS) method has been developed and validated for the simultaneous quantification of simvastatin (SS), simvastatin acid (SSA, active metabolite of SS) and ezetimibe (EZM) in K2 EDTA containing human plasma, using simvastatin D6, simvastatin acid D3 and ezetimibe D4 as internal standards (ISTDs), respectively. A volume of plasma sample of only 400 µL was processed by the solid phase extraction technique; then 20 µL of processed sample was run on a Phenomenex, Kinetix XB C18, 150 × 4...
July 2016: Journal of Chromatographic Science
https://www.readbyqxmd.com/read/27011926/association-of-yoga-practice-and-serum-cortisol-levels-in-chronic-periodontitis-patients-with-stress-related-anxiety-and-depression
#20
Kishore Kumar Katuri, Ankineedu Babu Dasari, Sruthi Kurapati, Narayana Rao Vinnakota, Appaiah Chowdary Bollepalli, Ravindranath Dhulipalla
AIM: Reducing the psychosocial stress by various methods can improve overall health, and yoga is now considered as an easily available alternative method. The present cross-sectional pilot study was conducted mainly to find the association of yoga practice with periodontal disease by measuring serum cortisol levels. MATERIALS AND METHODS: A total of 70 subjects with age range of 35-60 years suffering with chronic periodontitis were divided into group I (with stress), group II (without stress), and group III (practicing yoga)...
January 2016: Journal of International Society of Preventive & Community Dentistry
keyword
keyword
76757
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"