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https://www.readbyqxmd.com/read/29691755/my-patient-has-received-fluid-how-to-assess-its-efficacy-and-side-effects
#1
REVIEW
Xavier Monnet, Jean-Louis Teboul
Many efforts have been made to predict, before giving fluid, whether it will increase cardiac output. Nevertheless, after fluid administration, it is also essential to assess the therapeutic efficacy and to look for possible adverse effects. Like for any drug, this step should not be missed. Basically, volume expansion is aimed at improving tissue oxygenation and organ function. To assess this final result, clinical signs are often unhelpful. The increase in urine output in case of acute kidney injury is a poor marker of the kidney perfusion improvement...
April 24, 2018: Annals of Intensive Care
https://www.readbyqxmd.com/read/29690753/correlation-between-regional-tissue-perfusion-saturation-and-lactate-level-during-cardiopulmonary-bypass
#2
Yoon-Sook Lee, Woon Young Kim, Ji Won Yoo, Hyun Don Jung, Too Jae Min
Background: Cardiopulmonary bypass (CPB) can cause systemic hypoperfusion, which remains undetected by routine monitoring of physiological parameters. Noninvasive tissue perfusion monitoring offers a clinical benefit by detecting low systemic perfusion. In this study, we tried to evaluate whether regional tissue perfusion saturation reflects systemic hypoperfusion during CPB. Methods: This retrospective study included 29 patients with American Society of Anesthesiologists physical status II-III, who required cardiac surgery with CPB...
April 25, 2018: Korean Journal of Anesthesiology
https://www.readbyqxmd.com/read/29690736/-observation-on-safety-and-effects-of-analgesic-and-sedative-treatment-in-severely-burned-patients-during-shock-stage
#3
R B Li, Q Chen, H Y Zhang, H A Deng, G H Guo, Y G Mao, Z H Fu
Objective: To observe the safety and effects of application of analgesic and sedative drugs in severely burned patients during shock stage. Methods: One hundred and eighty patients with severe burns, conforming to the study criteria, were admitted to our unit from August 2014 to August 2016. Patients were divided into analgesia and sedation group and control group according to whether receiving analgesic and sedative treatment or not, with 90 cases in each group. Patients in control group received conventional treatment, while those in analgesia and sedation group received analgesic and sedative treatment for 24 hours besides conventional treatment...
April 20, 2018: Zhonghua Shao Shang za Zhi, Zhonghua Shaoshang Zazhi, Chinese Journal of Burns
https://www.readbyqxmd.com/read/29690686/-impaired-hypoxic-ventilatory-response-and-related-factors-in-han-and-uygur-patients-with-obstructive-sleep-apnea-hypopnea-syndrome
#4
Z M He, H Guo, X L Jiang, J P Li, Q L Zhang, Y P Yang, X S Dong, Piliqing Da, J Shi, M Li, M C Shi, F Han
Objective: To investigate the respiratory central hypoxia response and its related factors in Han and Uygur patients with obstructive sleep apnea hypopnea syndrome (OSAHS). Methods: One hundred and sixty six OSAHS patients were selected from Jan. 2016 to Dec. 2016 in Department of Respiratory and Critical Care Medicine, Kelamayi Central Hospital, including 69 cases of Han nationality and 97 cases of Uygur nationality. Seventy-three healthy subjects of Uygur nationality were enrolled as the control group. All of them under went sleep monitoring, nocturnal oxygen saturation (SaO(2)), pulmonary function and respiratory central hypoxia response...
April 12, 2018: Chinese Journal of Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/29689105/cerebral-desaturation-in-heart-failure-potential-prognostic-value-and-physiologic-basis
#5
Yu-Jen Chen, Jong-Shyan Wang, Chih-Chin Hsu, Pyng-Jing Lin, Feng-Chun Tsai, Ming-Shien Wen, Chi-Tai Kuo, Shu-Chun Huang
Cerebral tissue oxygen saturation (SctO2) reflects cerebral perfusion and tissue oxygen consumption, which decline in some patients with heart failure with reduced ejection fraction (HFrEF) or stroke, especially during exercise. Its physiologic basis and clinical significance remain unclear. We aimed to investigate the association of SctO2 with oxygen transport physiology and known prognostic factors during both rest and exercise in patients with HFrEF or stroke. Thirty-four HFrEF patients, 26 stroke patients, and 17 healthy controls performed an incremental cardiopulmonary exercise test using a bicycle ergometer...
2018: PloS One
https://www.readbyqxmd.com/read/29688787/comparison-of-desflurane-and-propofol-at-equipotent-doses-in-combination-with-a-constant-rate-infusion-of-dexmedetomidine-on-global-and-peripheral-perfusion-and-oxygenation-in-horses
#6
Stephan Neudeck, Sabine B R Kästner, Liza Wittenberg-Voges, Karl Rohn, Klaus Hopster
OBJECTIVE To determine global and peripheral perfusion and oxygenation during anesthesia with equipotent doses of desflurane and propofol combined with a constant rate infusion of dexmedetomidine in horses. ANIMALS 6 warmblood horses. PROCEDURES Horses were premedicated with dexmedetomidine (3.5 μg•kg-1 , IV). Anesthesia was induced with propofol or ketamine and maintained with desflurane or propofol (complete crossover design) combined with a constant rate infusion of dexmedetomidine (7 μg•kg-1 •h-1 )...
May 2018: American Journal of Veterinary Research
https://www.readbyqxmd.com/read/29687891/videolaryngoscopy-vs-fibreoptic-bronchoscopy-for-awake-tracheal-intubation-a-systematic-review-and-meta-analysis
#7
REVIEW
M Alhomary, E Ramadan, E Curran, S R Walsh
Awake fibreoptic intubation is often considered the technique of choice when a difficult airway is anticipated. However, videolaryngoscopes are being used more commonly. We searched the current literature and performed a meta-analysis to compare the use of videolaryngoscopy and fibreoptic bronchoscopy for awake tracheal intubation. Our primary outcome was the time needed to intubate the patient's trachea. Secondary outcomes included: failed intubation; the rate of successful intubation at the first attempt; patient-reported satisfaction with the technique; and any complications resulting from intubation...
April 17, 2018: Anaesthesia
https://www.readbyqxmd.com/read/29686815/the-effect-of-positive-end-expiratory-pressure-during-anesthesia-on-arterial-oxygen-saturation-after-surgery-in-patient-undergoing-cesarean-section
#8
Mahmood Ganjifard, Masoumeh Samii, Samaneh Kouzegaran, Amir Sabertanha
One of the major complications of general anesthesia in the recovery room is arterial oxygen desaturation and hypoxemia. Positive end-expiratory pressure (PEEP) can improve arterial oxygen saturation by increasing FRC. This study aims to evaluate the effects of applying PEEP on arterial oxygen saturation and hemodynamic parameters in the patient undergoing cesarean section in VALIASR hospital. In this double blind clinical trial we randomly allocated 120 patients of class1 and 2 ASA scheduled to undergoing cesarean section into 3 group (in 40)...
January 12, 2018: European Journal of Translational Myology
https://www.readbyqxmd.com/read/29686223/oxygen-consumption-of-the-aerobically-perfused-cardioplegic-donor-heart-at-different-temperatures
#9
Guangqi Qin, Yang Su, Trygve Sjöberg, Stig Steen
BACKGROUND The aim of this study was to investigate the oxygen consumption of explanted aerobically-perfused cardioplegic porcine hearts at different temperatures. MATERIAL AND METHODS Explanted hearts from 30 pigs weighing 50 kg were randomized into 5 groups. The hearts received continuous antegrade perfusion within a temperature-controlled sealed system. The perfusate consisted of an albumin-containing hyperoncotic cardioplegic nutrition solution with erythrocytes to a hematocrit of 10%. Five temperatures were studied: 37, 30, 22, 15, and 8°C...
April 24, 2018: Annals of Transplantation: Quarterly of the Polish Transplantation Society
https://www.readbyqxmd.com/read/29684832/effect-of-non-nutritive-sucking-and-sucrose-alone-and-in-combination-for-repeated-procedural-pain-in-preterm-infants-a-randomized-controlled-trial
#10
Haixia Gao, Mei Li, Honglian Gao, Guihua Xu, Fang Li, Jing Zhou, Yunsu Zou, Honghua Jiang
BACKGROUND: Sucrose combined with non-nutritive sucking provided better pain relief than sucrose or non-nutritive sucking alone in a single painful procedure. However, whether the combination of non-nutritive sucking with sucrose could obtain a significant difference in analgesic effect of the repeated procedural pain than any single intervention has not been established. OBJECTIVE: To compare the effect of non-nutritive sucking and sucrose alone and in combination of repeated procedural pain in preterm infants...
April 7, 2018: International Journal of Nursing Studies
https://www.readbyqxmd.com/read/29684443/modified-porcine-surfactant-enriched-by-recombinant-human-superoxide-dismutase-for-experimental-meconium-aspiration-syndrome
#11
Jana Kopincova, Pavol Mikolka, Maros Kolomaznik, Petra Kosutova, Andrea Calkovska, Daniela Mokra
AIMS: Combination of exogenous surfactant with antioxidant enzyme recombinant human superoxide dismutase (rhSOD) was tested in the treatment of experimental meconium aspiration syndrome as oxidative processes play key role in its pathogenesis. MATERIAL AND METHODS: Young New Zealand rabbits were instilled by saline (Sal group) or by meconium suspension (Mec group). Some of meconium-instilled animals were treated by surfactant alone (Surf group) or surfactant in combination with rhSOD (Surf + SOD group) and oxygen-ventilated for 5 h...
April 20, 2018: Life Sciences
https://www.readbyqxmd.com/read/29684433/oxygen-titration-after-resuscitation-from-out-of-hospital-cardiac-arrest-a-multi-centre-randomised-controlled-pilot-study-the-exact-pilot-trial
#12
Janet E Bray, Cindy Hein, Karen Smith, Michael Stephenson, Hugh Grantham, Judith Finn, Dion Stub, Peter Cameron
INTRODUCTION: Recent studies suggest the administration of 100% oxygen to hyperoxic levels following return-of-spontaneous-circulation (ROSC) post-cardiac arrest may be harmful. However, the feasibility and safety of oxygen titration in the prehospital setting is unknown. We conducted a multi-centre, phase-2 study testing whether prehospital titration of oxygen results in an equivalent number of patients arriving at hospital with oxygen saturations SpO2 ≥ 94%. METHODS: We enrolled unconscious adults with: sustained ROSC; initial shockable rhythm; an advanced airway; and an SpO2 ≥ 95%...
April 20, 2018: Resuscitation
https://www.readbyqxmd.com/read/29684249/standard-head-down-tilt-versus-modified-without-head-down-tilt-postural-drainage-in-infants-and-young-children-with-cystic-fibrosis
#13
REVIEW
Diana A Freitas, Gabriela Ss Chaves, Thayla A Santino, Cibele Td Ribeiro, Fernando Al Dias, Ricardo O Guerra, Karla Mpp Mendonça
BACKGROUND: Postural drainage is used primarily in infants with cystic fibrosis from diagnosis up to the moment when they are mature enough to actively participate in self-administered treatments. However, there is a risk of gastroesophageal reflux associated with this technique.This is an update of a review published in 2015. OBJECTIVES: To compare the effects of standard postural drainage (15º to 45º head-down tilt) with modified postural drainage (15º to 30º head-up tilt) with regard to gastroesophageal reflux in infants and young children up to six years old with cystic fibrosis in terms of safety and efficacy...
March 9, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29683104/association-of-epicardial-fat-thickness-with-clinical-and-polysomnographic-parameters-in-non-obese-obstructive-sleep-apnoea-patients
#14
S Derin, I Altun, S Koseoglu, C Sahin, M Yilmaz, F Akin, M Sahan
OBJECTIVES: This study aimed to investigate the relationship of epicardial fat thickness with severity of obstructive sleep apnoea, and clinical and polysomnographic parameters, and to determine independent predictors for epicardial fat thickness. METHODS: A total of 84 patients with a body mass index of less than 30 kg/m2 and suspected sleep-disordered breathing were included in the study. The correlations of epicardial fat thickness with polysomnographic and clinical data, and severity of obstructive sleep apnoea, were investigated...
April 23, 2018: Journal of Laryngology and Otology
https://www.readbyqxmd.com/read/29682321/use-of-biomedical-photonics-in-gynecological-surgery-a-uterine-transplantation-model
#15
Srdjan Saso, Neil T Clancy, Benjamin P Jones, Timothy Bracewell-Milnes, Maya Al-Memar, Eleanor M Cannon, Simran Ahluwalia, Joseph Yazbek, Meen-Yau Thum, Tom Bourne, Daniel S Elson, James Richard Smith, Sadaf Ghaem-Maghami
Aim: Uterine transplantation (UTx) has been proposed as a treatment for permanent absolute uterine factor infertility. The study aims were to compare pulse oximetry and multispectral imaging (MSI), for intraoperative tracking of uterine oxygen saturation in animal UTx models (rabbit and sheep). Results/methodology: Imaging results confirmed the re-establishment of adequate perfusion in the transplanted organ after surgery. Comparison of oxygen saturation   values between the pre-UTx donor and post-UTx recipient, and pre-UTx and post-UTx recipient reveals a statistically significant decrease in saturation levels post-UTx...
April 2018: Future Science OA
https://www.readbyqxmd.com/read/29682268/polysonographical-evaluation-in-a-case-of-moderate-osas-treated-with-mandibular-advancement-device
#16
A Venditti, M Basili, F M Ragazzoni, A Barlattani, P Bollero
Background: The Obstructive Sleep Apnea Syndrome (OSAS) is a clinical picture characterized by partial or complete obstruction of the upper airway during sleep, associated with a reduction of oxygen saturation in the blood.The most common symptoms are: apnea sleep, snoring, headache, sleepiness, reduced concentration and memory, irritability, increased blood pressure and dry mouth. Materials and methods: It was examinated a not-smoker man of 54 years that suffers of roncophaty...
October 2017: Oral & Implantology
https://www.readbyqxmd.com/read/29680471/the-neu-prem-trial-neuromonitoring-of-brains-of-infants-born-preterm-during-resuscitation-a-prospective-observational-cohort-study
#17
Anup C Katheria, M J Harbert, Sunil B Nagaraj, Kathy Arnell, Debra M Poeltler, Melissa K Brown, Wade Rich, Kasim O Hassen, Neil Finer
OBJECTIVE: To determine whether monitoring cerebral oxygen tissue saturation (StO2 ) with near-infrared spectroscopy (NIRS) and brain activity with amplitude-integrated electroencephalography (aEEG) can predict infants at risk for intraventricular hemorrhage (IVH) and death in the first 72 hours of life. STUDY DESIGN: A NIRS sensor and electroencephalography leads were placed on 127 newborns <32 weeks of gestational age at birth. Ten minutes of continuous NIRS and aEEG along with heart rate, peripheral arterial oxygen saturation, fraction of inspired oxygen, and mean airway pressure measurements were obtained in the delivery room...
April 16, 2018: Journal of Pediatrics
https://www.readbyqxmd.com/read/29680431/occurrence-of-nocturia-is-not-mediated-by-nocturnal-hypoxia-length-and-severity-in-patients-with-sleep-disordered-breathing
#18
P Finamore, S Scarlata, A Laudisio, F Galdi, M E Pipita, I Chiarella, R Giua, L Cortese, C Rivera, R Antonelli Incalzi
BACKGROUND: Nocturia is highly prevalent in subjects with respiratory sleep disturbances (ie obstructive sleep apnea). The aim of our study is to evaluate whether nocturia is associated with intermittent desaturations or hypoxia length and severity in people undergoing polysomnography. METHODS: We recruited 275 consecutive subjects attending the outpatient clinic for respiratory diseases at Campus Bio-Medico Teaching Hospital. Nocturia was defined as a self-reported voiding frequency ≥ two per night...
May 2018: Sleep Medicine
https://www.readbyqxmd.com/read/29680425/prevalence-and-characteristics-of-sleep-disordered-breathing-in-familial-dysautonomia
#19
Kanwaljit Singh, Jose-Alberto Palma, Horacio Kaufmann, Nataliya Tkachenko, Lucy Norcliffe-Kaufmann, Christy Spalink, Mikhail Kazachkov, Sanjeev V Kothare
OBJECTIVE: Familial dysautonomia (FD) is an autosomal recessive disorder characterized by impaired development of sensory and afferent autonomic nerves. Untreated sleep-disordered breathing (SDB) has been reported to increase the risk of sudden unexpected death in FD. We aimed to describe the prevalence and characteristics of SDB in FD. PATIENTS/METHODS: Seventy-five patients with FD (20 adults and 55 children) underwent in-lab polysomnography, including peripheral capillary oxygen saturation (SpO2 ) and end-tidal capnography (EtCO2 ) measurements...
May 2018: Sleep Medicine
https://www.readbyqxmd.com/read/29680394/the-clinical-effects-of-a-low-dose-dexmedetomidine-constant-rate-infusion-in-isoflurane-anesthetized-cats
#20
B T Simon, E M Scallan, C D Coursey, W M Kiehl, E J Moore
The aim of this study was to evaluate the effects of a low dose dexmedetomidine constant rate infusion (CRI) on cardiopulmonary function, inhalant anesthetic concentration and recovery in isoflurane anesthetized cats. In a prospective, randomized, blinded, controlled design, 12 cats undergoing anesthesia for ovariohysterectomy were administered hydromorphone (0.1mg/kg) intramuscularly, propofol (4.3-7.8mg/kg) intravenously and maintained with isoflurane. During isoflurane anesthesia, the cats were administered either a dexmedetomidine loading dose (0...
April 2018: Veterinary Journal
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