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https://www.readbyqxmd.com/read/29917060/perfect-permutation-filtering-test-for-microbiome-data
#1
Ekaterina Smirnova, Snehalata Huzurbazar, Farhad Jafari
The human microbiota composition is associated with a number of diseases including obesity, inflammatory bowel disease, and bacterial vaginosis. Thus, microbiome research has the potential to reshape clinical and therapeutic approaches. However, raw microbiome count data require careful pre-processing steps that take into account both the sparsity of counts and the large number of taxa that are being measured. Filtering is defined as removing taxa that are present in a small number of samples and have small counts in the samples where they are observed...
June 18, 2018: Biostatistics
https://www.readbyqxmd.com/read/29916964/perceived-partner-responsiveness-daily-negative-affect-reactivity-and-all-cause-mortality-a-20-year-longitudinal-study
#2
Sarah C E Stanton, Emre Selcuk, Allison K Farrell, Richard B Slatcher, Anthony D Ong
OBJECTIVE: This study tested longitudinal associations between absolute levels of perceived partner responsiveness (PPR; how much people feel their romantic partners understand, care for, and appreciate them), daily negative affect (NA) reactivity and positive affect (PA) reactivity, and all-cause mortality in a sample of 1,208 adults over three waves of data collection spanning 20 years. We also tested whether longitudinal changes in PPR predicted mortality via affect reactivity. METHODS: Data were taken from the National Survey of Midlife Development in the United States (MIDUS)...
June 18, 2018: Psychosomatic Medicine
https://www.readbyqxmd.com/read/29916935/mortality-after-total-knee-arthroplasty-a-systematic-review-of-incidence-temporal-trends-and-risk-factors
#3
James R Berstock, Andrew D Beswick, José A López-López, Michael R Whitehouse, Ashley W Blom
BACKGROUND: The capacity for total knee arthroplasty to improve pain, quality of life, and functional outcomes is widely recognized. Postoperative mortality is rare but of paramount importance, and needs to be accurately quantified and conveyed to patients in order to support decision-making prior to surgery. The purpose of this study was to determine a contemporary estimate of the risk of mortality following total knee arthroplasty, including the identification of temporal trends, common causes, and modifiable and nonmodifiable risk factors...
June 20, 2018: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/29916563/-digitalisation-and-clinical-care-pathways-in-rehabilitation-medicine-a-possible-integration-from-the-goal-planning-and-the-rehabilitation-programme-design-to-the-evaluation-of-clinical-outcomes
#4
Anna Giardini, Silvia Traversoni, Claudio Garbelli, Anna Lodigiani
OBJECTIVES: In the light of the growing complexity featuring the contemporary world, a future challenge is represented by the maintenance of the humanization of healthcare, along with the necessity of a high specificity personalized treatment, in a growing emergency of lack of resources. Furthermore, the ongoing digital revolution spreading in every productive sector involves the health-care system as well, playing a crucial role for the goals of the specialized care-related prevention-treatment-rehabilitation approach of the Rehabilitation Medicine...
February 2018: Giornale Italiano di Medicina del Lavoro Ed Ergonomia
https://www.readbyqxmd.com/read/29916414/does-clinical-governance-influence-the-quality-of-medical-records
#5
Andrea Poscia, Elena Azzolini, Pasquale Cacciatore, Antonio Giulio de Belvis, Massimo Volpe, Andrea Cambieri, Gianfranco Damiani, Walter Ricciardi, Maria Lucia Specchia
BACKGROUND: Clinical Governance (CG) is a validated framework for continuous quality improvement in health care settings. Quality medical records may reflect the quality of care delivered and are a viable tool to implement CG skills. AIM: Aim of this study is to investigate the correlation between the level of implementation of CG dimensions and the quality of medical records. MATERIAL AND METHODS: A cross-sectional study was carried out in an Italian Teaching Hospital...
April 2018: Annali Dell'Istituto Superiore di Sanità
https://www.readbyqxmd.com/read/29915641/effects-of-educational-messaging-on-urgent-and-emergent-care-seeking-behaviors-among-publicly-insured-populations
#6
Jesse Cambon, Tristan Cordier, Elizabeth L Munnich, Andrew Renda, Bobby Kapur, Shkelzen Hoxhaj, Meredith Williams
Background: The impact of messaging campaigns on influencing urgent care- and emergent care-seeking behaviors, including the use of in-network providers, is not well-understood. Although out-of-network healthcare utilization can have negative financial consequences for patients in narrow network Affordable Care Act plans, individuals with time-sensitive medical conditions, and especially patients visiting the emergency department, may not think about out-of-network issues. Inappropriate or avoidable emergency department visits can also create unnecessary costs for patients...
April 2018: American Health & Drug Benefits
https://www.readbyqxmd.com/read/29914880/antibiotic-prescribing-for-acute-respiratory-tract-infections-in-primary-care-an-updated-and-expanded-meta-ethnography
#7
Evi Germeni, Julia Frost, Ruth Garside, Morwenna Rogers, Jose M Valderas, Nicky Britten
BACKGROUND: Reducing unnecessary prescribing remains a key priority for tackling the global rise of antibiotic-resistant infections. AIM: The authors sought to update a 2011 qualitative synthesis of GPs' experiences of antibiotic prescribing for acute respiratory tract infections (ARTIs), including their views of interventions aimed at more prudent prescribing. They expanded the original scope to encompass all primary care professionals (PCPs) who can prescribe or dispense antibiotics for ARTIs (for example, nurses and pharmacists)...
June 18, 2018: British Journal of General Practice: the Journal of the Royal College of General Practitioners
https://www.readbyqxmd.com/read/29914871/secondary-peritonitis-principles-of-diagnosis-and-intervention
#8
REVIEW
James T Ross, Michael A Matthay, Hobart W Harris
Secondary peritonitis accounts for 1% of urgent or emergent hospital admissions and is the second leading cause of sepsis in patients in intensive care units globally. Overall mortality is 6%, but mortality rises to 35% in patients who develop severe sepsis. Despite the dramatic growth in the availability and use of imaging and laboratory tests, the rapid diagnosis and early management of peritonitis remains a challenge for physicians in emergency medicine, surgery, and critical care. In this article, we review the pathophysiology of peritonitis and its potential progression to sepsis, discuss the utility and limitations of the physical examination and laboratory and radiographic tests, and present a paradigm for the management of secondary peritonitis...
June 18, 2018: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/29914411/access-to-primary-care-for-socio-economically-disadvantaged-older-people-in-rural-areas-exploring-realist-theory-using-structural-equation-modelling-in-a-linked-dataset
#9
John A Ford, Andy Jones, Geoff Wong, Allan Clark, Tom Porter, Nick Steel
BACKGROUND: Realist approaches seek to answer questions such as 'how?', 'why?', 'for whom?', 'in what circumstances?' and 'to what extent?' interventions 'work' using context-mechanism-outcome (CMO) configurations. Quantitative methods are not well-established in realist approaches, but structural equation modelling (SEM) may be useful to explore CMO configurations. Our aim was to assess the feasibility and appropriateness of SEM to explore CMO configurations and, if appropriate, make recommendations based on our access to primary care research...
June 19, 2018: BMC Medical Research Methodology
https://www.readbyqxmd.com/read/29914401/-they-re-born-to-get-breastfed-how-fathers-view-breastfeeding-a-mixed-method-study
#10
Emily Hansen, Leigh Tesch, Jennifer Ayton
BACKGROUND: Fathers' attitudes and actions can positively or negatively affect mothers' intentions to breastfeed, breastfeeding duration and exclusivity. In-depth information about fathers' perspectives on breastfeeding are largely absent in the literature about infant feeding. The objective of this research was to investigate how fathers view breastfeeding. METHODS: This mixed method study recruited Tasmanian fathers with children < 24 months of age. Fathers completed a questionnaire and participated in either semi structured one-on-one or group interviews...
June 18, 2018: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29914288/progressive-hearing-loss-among-patients-with-cystic-fibrosis-and-parenteral-aminoglycoside-treatment
#11
Erika M Zettner, Malcolm A Gleser
Objective Hearing loss is a significant and growing problem as patients with cystic fibrosis (CF) live longer and experience frequent courses of intravenous aminoglycoside antibiotics (hereafter, "IVs"). This study seeks to document that risk in a large adult population with CF, accounting for age and aminoglycoside exposure. Study Design Retrospective case review of patients with CF who had multiple audiograms over years. Setting Tertiary care cystic fibrosis setting. Subject and Methods The first and last audiograms recorded over a 10-year period were compared for 165 adult patients with CF...
June 1, 2018: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/29913889/the-association-between-physicians-attitudes-to-psychosocial-aspects-of-low-back-pain-and-reported-clinical-behaviour-a-complex-issue
#12
Anna L Valjakka, Sanna Salanterä, Aarno Laitila, Juhani Julkunen, Nora M Hagelberg
Background and aim Physicians' attitudes predict clinical decision making and treatment choices, but the association between attitudes and behaviour is complex. Treatment guidelines for non-specific low back pain (LBP) include recommendations of early assessment of psychosocial risk factors forchronic pain, patient education and reassurance. Implication of these principles is demanding, and many patients are not referred for appropriate treatments due to a lack of systematic screening of psychosocial risk factors for chronic pain...
December 29, 2017: Scandinavian Journal of Pain
https://www.readbyqxmd.com/read/29913685/quality-pain-management-in-the-hospital-setting-a-concept-evaluation
#13
S Zoëga, S Gunnarsdóttir, D B Gordon
Aims To gain an understanding of the concept of quality pain management (QPM) in the hospital setting, and to define the concept. Methods A concept evaluation based on the method by Morse and colleagues was done. The literature was searched according to selected key words in five databases. Over 5000 articles were found but data were limited to 37 articles directly related to both quality and pain management in adults in the hospital setting, and published in peer-reviewed journals or by an official organization...
December 29, 2017: Scandinavian Journal of Pain
https://www.readbyqxmd.com/read/29913523/dental-imaging-a-basic-guide-for-the-radiologist
#14
Max Masthoff, Mirjam Gerwing, Malte Masthoff, Maximilian Timme, Johannes Kleinheinz, Markus Berninger, Walter Heindel, Moritz Wildgruber, Christoph Schülke
BACKGROUND:  As dental imaging accounts for approximately 40 % of all X-ray examinations in Germany, profound knowledge of this topic is essential not only for the dentist but also for the clinical radiologist. This review focuses on basic imaging findings regarding the teeth. Therefore, tooth structure, currently available imaging techniques and common findings in conserving dentistry including endodontology, periodontology, implantology and dental trauma are presented. METHODS:  Literature research on the current state of dental radiology was performed using Pubmed...
June 18, 2018: RöFo: Fortschritte Auf Dem Gebiete der Röntgenstrahlen und der Nuklearmedizin
https://www.readbyqxmd.com/read/29913100/hospitalization-trends-and-comorbidities-among-people-with-hiv-aids-compared-with-the-overall-hospitalized-population-illinois-2008-2014
#15
Livia Navon
OBJECTIVES: To understand trends in health care use among people living with HIV/AIDS (PLWHA), this study compared trends in hospitalization rates, comorbidities, and hospital death rates of hospitalized PLWHA with the overall hospitalized population in Illinois during 2008-2014. METHODS: This study identified principal hospitalizations (the principal discharge diagnosis coded with an HIV-related billing code) and secondary HIV hospitalizations (a non-principal discharge diagnosis coded with an HIV-related billing code) from 2008-2014 Illinois hospital discharge data...
January 1, 2018: Public Health Reports
https://www.readbyqxmd.com/read/29912954/impact-of-smartphone-assisted-prenatal-home-visits-on-women-s-use-of-facility-delivery-results-from-a-cluster-randomized-trial-in-rural-tanzania
#16
Kristy Hackett, Curtis Lafleur, Peter Nyella, Ophira Ginsburg, Wendy Lou, Daniel Sellen
BACKGROUND: About half of births in rural Tanzania are assisted by skilled providers. Point-of-care mobile phone applications hold promise in boosting job support for community health workers aiming to ensure safe motherhood through increased facility delivery awareness, access and uptake. We conducted a controlled comparison to evaluate a smartphone-based application designed to assist community health workers with data collection, education delivery, gestational danger sign identification, and referrals...
2018: PloS One
https://www.readbyqxmd.com/read/29912839/greater-reductions-in-readmission-rates-achieved-by-urban-hospitals-participating-in-the-medicare-shared-savings-program
#17
Yeunkyung Kim, Caroline P Thirukumaran, Yue Li
BACKGROUND: Accountable Care Organizations in the Medicare Shared Savings Program (MSSP) have financial incentives to reduce the cost and improve the quality of care delivered to Medicare beneficiaries that they serve. However, previous research about the impact of the MSSP on readmissions is limited and mixed. OBJECTIVE: To examine the association between hospital participation in the MSSP during the 2012-2013 period and reductions in 30-day risk-standardized readmission rates for Medicare patients initially admitted for acute myocardial infarction, heart failure (HF), pneumonia, or any cause...
June 15, 2018: Medical Care
https://www.readbyqxmd.com/read/29912815/monitoring-self-reported-adherence-to-antiretroviral-therapy-in-public-hiv-care-facilities-in-brazil-a-national-cross-sectional-study
#18
Maria Altenfelder Santos, Mark Drew Crosland Guimarães, Ernani Tiaraju Santa Helena, Cáritas Relva Basso, Felipe Campos Vale, Wania Maria do Espírito Santo Carvalho, Ana Maroso Alves, Gustavo Machado Rocha, Francisco de Assis Acurcio, Maria das Graças Braga Ceccato, Rogério Ruscitto do Prado, Paulo Rossi Menezes, Maria Ines Batistella Nemes
INTRODUCTION: Patient adherence to antiretroviral therapy (ART) is critical for HIV treatment success. Monitoring rates of adherence in public HIV outpatient care facilities can improve outcomes in Brazil where ART is universally available. METHODS: We conducted a national cross-sectional survey of ART adherence in 2010. Participants were selected using a multistage probability sample. First, HIV outpatient care facilities were stratified according to 7 Organizational Quality Classification (OQC) groups and regions...
May 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29912772/stevens-johnson-syndrome-and-toxic-epidermal-necrolysis-like-lupus-erythematosus
#19
Jutamas Tankunakorn, Sirima Sawatwarakul, Vasanop Vachiramon, Kumutnart Chanprapaph
BACKGROUND/OBJECTIVE: Stevens-Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN)-like lupus erythematosus is a hyperacute and life-threatening form of cutaneous lupus erythematosus. Because of its rarity, little is known about this entity. We aimed to evaluate the clinical characteristics, laboratory findings, systemic manifestations, treatments, and outcome of SJS/ TEN-like lupus erythematosus. METHODS: We conducted a chart review study from July 2002 to September 2016 of all patients diagnosed with SJS/TEN-like lupus erythematosus who presented with gradual epidermal necrolysis without clear drug or infectious culprit...
June 15, 2018: Journal of Clinical Rheumatology: Practical Reports on Rheumatic & Musculoskeletal Diseases
https://www.readbyqxmd.com/read/29912593/cost-estimate-of-platelet-transfusion-in-the-united-states-for-patients-with-chronic-liver-disease-and-associated-thrombocytopenia-undergoing-elective-procedures
#20
Christine L Barnett, Deirdre Mladsi, Michael Vredenburg, Kavita Aggarwal
AIMS: This study aimed to estimate the cost of platelet transfusion in patients with chronic liver disease (CLD)-associated thrombocytopenia undergoing an elective procedure in the United States. MATERIALS AND METHODS: The study was conducted in 2 parts: development of a conceptual framework identifying direct, indirect, and intangible costs of platelet transfusion, followed by the estimation of the total cost of platelet transfusion in patients with CLD-associated thrombocytopenia before an elective procedure in the United States using the conceptual framework and cost data obtained from a literature search...
June 18, 2018: Journal of Medical Economics
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