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https://www.readbyqxmd.com/read/28932351/abdominal-tuberculosis-is-there-a-role-for-surgery
#1
REVIEW
Elroy Patrick Weledji, Benjamin Thumamo Pokam
It is important that surgeons are familiar with the various manifestations of tuberculosis (TB). Although TB has been declining in incidence in the developed world, it remains an important problem in endemic areas of the developing world. The aim of the review was to elucidate the natural history and characteristics of abdominal TB and ascertain the indications for surgery. TB can affect the intestine as well as the peritoneum and the most important aspect of abdominal TB is to bear in mind the diagnosis and obtain histological evidence...
August 27, 2017: World Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/28931203/scalpel-versus-electrosurgery-for-major-abdominal-incisions
#2
REVIEW
Kittipat Charoenkwan, Zipporah Iheozor-Ejiofor, Kittipan Rerkasem, Elizabeth Matovinovic
BACKGROUND: Scalpels or electrosurgery can be used to make abdominal incisions. The potential benefits of electrosurgery may include reduced blood loss, dry and rapid separation of tissue, and reduced risk of cutting injury to surgeons. Postsurgery risks possibly associated with electrosurgery may include poor wound healing and complications such as surgical site infection. OBJECTIVES: To assess the effects of electrosurgery compared with scalpel for major abdominal incisions...
June 14, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28930831/accessory-spleen-located-in-the-right-parietal-peritoneum-the-first-case-report
#3
Shao-Yan Xu, Ke Sun, Hai-Yang Xie, Lin Zhou, Shu-Sen Zheng, Weilin Wang
RATIONALE: Accessory spleen is a congenital abnormality caused by failure of the splenic anlage to fuse during embryology. The presence of an accessory spleen located in the parietal peritoneum has not been reported so far, and an accessory spleen situated on the right side is extremely rare. In the present study, we describe the first case of an accessory spleen located in the right parietal peritoneum. PATIENTS CONCERNS: A 65-year-old man, presented with pain in his left abdomen for 1 month...
September 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28928329/single-incision-trocar-less-endoscopic-management-of-giant-liver-hydatid-cyst-in-children
#4
Himanshu Acharya, Vikesh Agrawal, Abhishek Tiwari, Dhananjaya Sharma
INTRODUCTION: Laparoscopic management of giant hydatid cyst has limitations such as spillage, poor control, difficulties in suctioning the contents through special ports which are not easily available, difficulty in the obliteration of residual cavity and recurrence. We describe single-incision trocar-less endoscopic (SITE) technique which simplifies enucleation and management of residual cavity. METHOD: Inclusion criteria for these cases were patients having single uncomplicated giant hydatid cyst >5 cm present at the surface of the liver and palpable on clinical examination...
September 20, 2017: Journal of Minimal Access Surgery
https://www.readbyqxmd.com/read/28924599/esophageal-seeding-after-endoscopic-ultrasound-guided-fine-needle-aspiration-of-a-mediastinal-tumor
#5
Kensuke Yokoyama, Jun Ushio, Norikatsu Numao, Kiichi Tamada, Noriyoshi Fukushima, Alan Kawarai Lefor, Hironori Yamamoto
Background and study aims  Tumor seeding after endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) is rare. A 53-year-old man underwent transesophageal EUS-FNA for diagnosis of a 6-cm mass in the mediastinum as seen by computed tomography (CT). Four weeks later, repeat CT scan revealed a mass in the esophageal wall. Upper gastrointestinal endoscopy confirmed a lesion in the mid-esophagus, which was biopsied and found to be consistent with needle tract seeding after EUS-FNA. Tumor seeding in the gastrointestinal wall or peritoneum after EUS-FNA is rare, but may adversely affect the prognosis...
September 2017: Endoscopy International Open
https://www.readbyqxmd.com/read/28919998/reciprocal-influence-of-b-cells-and-tumor-macro-and-microenvironments-in-the-apc-min-model-of-colorectal-cancer
#6
Francesca Mion, Stefania Vetrano, Silvia Tonon, Viviana Valeri, Andrea Piontini, Alessia Burocchi, Luciana Petti, Barbara Frossi, Alessandro Gulino, Claudio Tripodo, Mario P Colombo, Carlo E Pucillo
One of the most fascinating aspects of the immune system is its dynamism, meant as the ability to change and readapt according to the organism needs. Following an insult, we assist to the spontaneous organization of different immune cells which cooperate, locally and at distance, to build up an appropriate response. Throughout tumor progression, adaptations within the systemic tumor environment, or macroenvironment, result in the promotion of tumor growth, tumor invasion and metastasis to distal organs, but also to dramatic changes in the activity and composition of the immune system...
2017: Oncoimmunology
https://www.readbyqxmd.com/read/28919578/selectin-independent-adhesion-during-ovarian-cancer-metastasis
#7
Nadezhda A Khaustova, Diana V Maltseva, Leticia Oliveira-Ferrer, Christine Stürken, Karin Milde-Langosch, Julia A Makarova, Sergey Rodin, Udo Schumacher, Alexander G Tonevitsky
PURPOSE: Ovarian cancer (OvCa) progression mainly takes place by intraperitoneal spread. Adhesion of tumor cells to the mesothelial cells which form the inner surface of the peritoneum is a crucial step in this process. Cancer cells use in principle different molecules of the leukocyte adhesion cascade to facilitate adhesion. This cascade is initiated by selectin-ligand interactions followed by integrin - extracellular matrix protein interactions. Here we address the question whether all tumor cells predominantly employ selectin-dependent leukocyte-like adhesion cascade (SDAC) or whether they use integrin mediated adhesion for OvCa progression as well...
September 14, 2017: Biochimie
https://www.readbyqxmd.com/read/28912509/aspirin-inhibits-lps-induced-macrophage-activation-via-the-nf-%C3%AE%C2%BAb-pathway
#8
Yitong Liu, Silian Fang, Xiaoyan Li, Jie Feng, Juan Du, Lijia Guo, Yingying Su, Jian Zhou, Gang Ding, Yuxing Bai, Songling Wang, Hao Wang, Yi Liu
Aspirin (acetylsalicylic acid, ASA) has been shown to improve bone marrow mesenchymal stem cell-based calvarial bone regeneration by promoting osteogenesis and inhibiting osteoclastogenesis. However, it remains unknown whether aspirin influences other immune cells during bone formation. In the present study, we investigated whether ASA treatment influenced macrophage activation during the LPS inducement. We found that ASA could downregulate the expressions of iNOS and TNF-α both in mouse peritoneum macrophages and RAW264...
September 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28904922/report-of-a-case-and-review-of-literature-of-internal-hernia-through-peritoneal-defect-in-pouch-of-douglas-a-rare-occurrence
#9
Vamseedharan Muthukumar, Sarveswaran Venugopal, Surees Kumar Subramaniam
Intestinal obstruction attributable to internal hernia as a cause is a rare phenomenon with a reported incidence of 0.6%-5.8%. Internal hernias ensuing as a result of defect in the pouch of Douglas is extremely rare with only six such cases reported so far in the literature. We present a case of 74-year-old posthysterectomy status female who presented with features of intestinal obstruction. Intraoperatively, the site of obstruction was found to be a rent in the peritoneum of the pouch of Douglas through which a loop of ileum was found herniating...
July 2017: International Journal of Applied and Basic Medical Research
https://www.readbyqxmd.com/read/28903762/mesh-penetrating-the-cecum-and-bladder-following-inguinal-hernia-surgery-a-case-report
#10
Hiroshi Asano, Saori Yajima, Yoshie Hosoi, Makoto Takagi, Hiroyuki Fukano, Yasuhiro Ohara, Nozomi Shinozuka, Takaya Ichimura
BACKGROUND: Tension-free repair using mesh is a common inguinal hernia surgical procedure. However, various complications such as mesh-related infection and recurrence may develop as a result. Moreover, although rare, there are also reports of intestinal obstruction caused by adhesion of the mesh to the intestinal wall and cases of mesh migration into various organs. Here, we report our experience with a patient in whom mesh extraction was performed due to migration of mesh into the intestinal tract following inguinal hernia surgery and formation of a fistula with the bladder...
September 14, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28903471/the-role-of-tgf-%C3%AE-in-the-pathophysiology-of-peritoneal-endometriosis
#11
Vicky J Young, S F Ahmad, W Colin Duncan, Andrew W Horne
BACKGROUND: Endometriosis is estimated to affect 6-10% of women of reproductive age and it is associated with chronic pelvic pain, dysmenorrhoea and subfertility. It is currently managed surgically or medically but symptoms recur in up to 75% of cases and available medical treatments have undesirable side effects. Endometriosis is defined as the presence of endometrial tissue outside the uterus with lesions typically found on the peritoneum. The aetiology of endometriosis is uncertain but there is increasing evidence that transforming growth factor (TGF)-β plays a major role...
September 1, 2017: Human Reproduction Update
https://www.readbyqxmd.com/read/28901815/high-grade-b-cell-lymphoma-of-the-peritoneum-as-a-result-of-transformation-of-a-cd5-negative-monoclonal-b-lymphocytosis-population-in-a-patient-with-myelodysplastic-syndrome-treated-with-5-azacytidine
#12
Maria Dimou, Maria Roumelioti, Aglaia Dimitrakopoulou, Catherin Bitsani, Sotiria Kotsanti, Panayiota Petsa, Paraskevi Papaioannou, Marie-Christine Kyrtsonis, Panayiotis Panayiotidis
No abstract text is available yet for this article.
September 13, 2017: Leukemia & Lymphoma
https://www.readbyqxmd.com/read/28901453/the-role-of-gene-polymorphisms-in-endometriosis
#13
Michail Matalliotakis, Maria I Zervou, Charoula Matalliotaki, Nilufer Rahmioglu, George Koumantakis, Ioannis Kalogiannidis, Ioannis Prapas, Krina Zondervan, Demetrios A Spandidos, Ioannis Matalliotakis, George N Goulielmos
Endometriosis is a benign gynecologic disorder, affecting up to 10% of women, characterized by the presence of functional endometrial tissue at ectopic positions generally within the peritoneum. It is a heritable condition influenced by multiple genetic and environmental factors, with an overall heritability estimated at approximately 50%. In this study, we investigated whether single nucleotide polymorphisms (SNPs) rs7521902, rs10859871 and rs11031006, mapping to WNT4, VEZT and FSHB genetic loci, respectively, are associated with risk for endometriosis in a Greek population...
August 29, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28901396/effect-of-1-25-oh-2d3-on-high-glucose%C3%A2-induced-autophagy-inhibition-in-peritoneum
#14
Lina Yang, Yi Fan, Xiuli Zhang, Jin Liu, Jianfei Ma
High glucose (HG) may damage the structure and function of the peritoneal membrane, and is considered to be one of the most important factors that leads to peritoneal fibrosis and ultrafiltration failure. Recently, 1,25(OH)2D3, the active form of vitamin D, was demonstrated to protect against epithelial‑mesenchymal transition and fibrosis in peritoneal mesothelium and other organs. Accumulating evidence has suggested that autophagy serves a protective role in certain diseases by regulating cell survival...
August 31, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28898232/crosstalk-between-tems-and-endothelial-cells-modulates-angiogenesis-and-metastasis-via-igf1-igf1r-signalling-in-epithelial-ovarian-cancer
#15
Xinjing Wang, Qinyi Zhu, Yingying Lin, Li Wu, Xiaoli Wu, Kai Wang, Qizhi He, Congjian Xu, Xiaoping Wan, Xipeng Wang
BACKGROUND: Epithelial ovarian cancer (EOC) is the leading cause of death from gynaecologic malignancies and has a poor prognosis due to metastasis. Drugs targeting the angiogenesis pathway significantly improve patient outcome. However, the key factors linking angiogenesis and metastasis have not been elucidated. In this study, we found Tie2 expressing monocytes (CD14(+)Tie2(+), TEMs) as key contributors to angiogenesis and metastasis of EOC. METHODS: Tissue slides were evaluated by immunofluorescence for the presence of total tissue macrophages and TEMs...
September 12, 2017: British Journal of Cancer
https://www.readbyqxmd.com/read/28892097/ligand-mediated-cytoplasmic-retention-of-the-ah-receptor-inhibits-macrophage-mediated-acute-inflammatory-responses
#16
Gulsum E Muku, Tejas S Lahoti, Iain A Murray, Michael A Podolsky, Kayla J Smith, Troy D Hubbard, Guray Kuzu, Krishne Gowda, Shantu G Amin, Gary H Perdew
The Ah receptor (AHR) has been shown to exhibit both inflammatory and anti-inflammatory activity in a context-specific manner. In vivo macrophage-driven acute inflammation models were utilized here to test whether the selective Ah receptor modulator 1-allyl-7-trifluoromethyl-1H-indazol-3-yl]-4-methoxyphenol (SGA360) would reduce inflammation. Exposure to SGA360 was capable of significantly inhibiting lipopolysaccharide (LPS)-mediated endotoxic shock in a mouse model, both in terms of lethality and attenuating inflammatory signaling in tissues...
September 11, 2017: Laboratory Investigation; a Journal of Technical Methods and Pathology
https://www.readbyqxmd.com/read/28891847/prognostic-significance-of-peritoneal-metastasis-in-stage-iv-colorectal-cancer-patients-with-r0-resection-a-multicenter-retrospective-study
#17
Keiichi Arakawa, Kazushige Kawai, Soichiro Ishihara, Keisuke Hata, Hiroaki Nozawa, Koji Oba, Kenichi Sugihara, Toshiaki Watanabe
BACKGROUND: Stage IV colorectal cancer encompasses various clinical conditions. The differences in prognosis after surgery between different metastatic organs have not been fully investigated. OBJECTIVE: This study aimed to assess prognostic significance in peritoneal metastasis in R0 resected stage IV colorectal cancer. DESIGN: We conducted a multicenter retrospective study of patients with R0 resected stage IV colorectal cancer; they were categorized into 3 groups according to the number and location of metastatic organs, including single-organ metastasis in the peritoneum, single-organ metastasis at sites except the peritoneum, and multiple-organ metastases...
October 2017: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/28886329/a-case-of-igg4-related-retroperitoneal-fibrosis-with-multiple-involvement
#18
Y-K Zheng, N-Y Gu, J Wu, X Fang, C Zhang, Q-Y Li
To increase awareness of IgG4-related retroperitoneal fibrosis (IgG4-RRPF) and reduce clinical misdiagnosis. We report a 79-year-old man with multiple organs involvement of IgG4-RRPF, who developed right lower extremity edema, hemoptysis and fever. The abdomen computed tomography (CT) scan image showed lymph nodes enlargement. The positron emission tomography/CT scan image showed pancreatic malignancy with multiple nodal lymph node metastasis, lung fibroblast proliferation, and right lung apex bullae. The chest CT scan image showed pulmonary multiple lymph nodes with calcification in the mediastinum...
August 30, 2017: Cellular and Molecular Biology
https://www.readbyqxmd.com/read/28885718/transvaginal-ultrasound-guided-core-needle-biopsy-of-pelvic-masses
#19
Shi-Yang Lin, Yong-Hong Xiong, Miao Yun, Long-Zhong Liu, Wei Zheng, Xi Lin, Xiao-Qing Pei, An-Hua Li
OBJECTIVES: This study assessed the efficacy and safety of transvaginal ultrasound (US)-guided core needle biopsy (CNB) for obtaining adequate pelvic mass samples for histologic analysis and evaluated factors that may affect biopsy success. METHODS: Two hundred cases underwent transvaginal US-guided CNBs for primary inoperable tumors, suspicion of metastases to the ovaries or peritoneum, recurrence, or other solid lesions in the pelvis. Biopsy samples were obtained from the pelvic cavity (67...
September 8, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/28883764/prognostic-significance-diagnosis-and-treatment-in-patients-with-gastric-cancer-and-positive-peritoneal-washings-a-review-of-the-literature
#20
REVIEW
Radosław Lisiecki, Małgorzata Kruszwicka, Arkadiusz Spychała, Dawid Murawa
Peritoneal dissemination is a common consequence of a relapse following a radical surgical treatment of gastric cancer. The development of the disease in the peritoneum depends not only on its stage, but also on free cancer cells exfoliated from the tumor mass or from involved lymph nodes, and which are capable of being implanted in the peritoneum. According to the latest TNM (7 edition; 2010) classification, patients with free cancer cells in the peritoneal washings qualify for stage IV of the disease. Patients in whom free cancer cells were found during the operation - have a recurrence of gastric cancer - mainly in the peritoneum, and the majority of them die within two years of the diagnosis...
November 2017: Reports of Practical Oncology and Radiotherapy
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