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https://www.readbyqxmd.com/read/27907897/cost-effectiveness-of-embryo-transfer-strategies-a-decision-analytic-model-using-long-term-costs-and-consequences-of-singletons-and-multiples-born-as-a-consequence-of-ivf
#1
M M J van Heesch, A D I van Asselt, J L H Evers, M A H B M van der Hoeven, J C M Dumoulin, C E M van Beijsterveldt, G J Bonsel, R H M Dykgraaf, J B van Goudoever, C Koopman-Esseboom, W L D M Nelen, K Steiner, P Tamminga, N Tonch, H L Torrance, C D Dirksen
STUDY QUESTION: What is the cost-effectiveness of elective single embryo transfer (eSET) versus double embryo transfer (DET) strategies from a societal perspective, when applying a time horizon of 1, 5 and 18 years? SUMMARY ANSWER: From a short-term perspective (1 year) it is cost-effective to replace DET with single embryo transfer; however when intermediate- (5 years) and long-term (18 years) costs and consequences are incorporated, DET becomes the most cost-effective strategy, given a ceiling ratio of €20 000 per quality-adjusted life years (QALY) gained...
November 2016: Human Reproduction
https://www.readbyqxmd.com/read/27901293/live-birth-sex-ratios-and-father-s-geographic-origins-in-jerusalem-1964-1976
#2
J Groeger, M Opler, K Kleinhaus, M C Perrin, R Calderon-Margalit, O Manor, O Paltiel, D Conley, S Harlap, D Malaspina
OBJECTIVE: To examine whether ancestry influenced sex ratios of offspring in a birth cohort before parental antenatal sex selection influenced offspring sex. METHODS: We measured the sex ratio as the percent of males according to countries of birth of paternal and maternal grandfathers in 91,459 live births from 1964 to 1976 in the Jerusalem Perinatal Study. Confidence limits (CI) were computed based on an expected sex ratio of 1.05, which is 51.4% male. RESULTS: Of all live births recorded, 51...
November 30, 2016: American Journal of Human Biology: the Official Journal of the Human Biology Council
https://www.readbyqxmd.com/read/27885583/using-gis-mapping-to-target-public-health-interventions-examining-birth-outcomes-across-gis-techniques
#3
E L MacQuillan, A B Curtis, K M Baker, R Paul, Y O Back
With advances in spatial analysis techniques, there has been a trend in recent public health research to assess the contribution of area-level factors to health disparity for a number of outcomes, including births. Although it is widely accepted that health disparity is best addressed by targeted, evidence-based and data-driven community efforts, and despite national and local focus in the U.S. to reduce infant mortality and improve maternal-child health, there is little work exploring how choice of scale and specific GIS visualization technique may alter the perception of analyses focused on health disparity in birth outcomes...
November 24, 2016: Journal of Community Health
https://www.readbyqxmd.com/read/27884968/dissenting-from-care-data-an-analysis-of-opt-out-forms
#4
Paraskevas Vezyridis, Stephen Timmons
BACKGROUND: Care.data was a programme of work led by NHS England for the extraction of patient-identifiable and coded information from general practitioner (GP) records for secondary uses. This study analyses the forms (on the websites of GP practices) which enabled patients to opt out. METHODS: Theoretical sampling and summative content analysis were used to collect and analyse dissent forms used by patients to opt out from care. DATA: Domains included basic information about the programme, types of objections and personal details required for identification purposes...
December 2016: Journal of Medical Ethics
https://www.readbyqxmd.com/read/27884492/what-women-want-exploring-pregnant-women-s-preferences-for-alternative-models-of-maternity-care
#5
Christopher Godfrey Fawsitt, Jane Bourke, Jennifer E Lutomski, Sarah Meaney, Brendan McElroy, Rosemary Murphy, Richard Anthony Greene
Depending on obstetric risk, maternity care may be provided in one of two locations at hospital level: a consultant-led unit (CLU) or a midwifery-led unit (MLU). Care in a MLU is sparsely provided in Ireland, comprising as few as two units out of a total 21 maternity units. Given its potential for greater efficiencies of care and cost-savings for the state, there has been an increased interest to expand MLUs in Ireland. Yet, very little is known about women's preferences for midwifery-led care, and whether they would utilise this service when presented with the choice of delivering in a CLU or MLU...
November 8, 2016: Health Policy
https://www.readbyqxmd.com/read/27873347/infantile-hemangioma-with-minimal-or-arrested-growth-further-observations-on-clinical-and-histopathologic-findings-of-this-unique-but-underrecognized-entity
#6
Ellen Hui Ma, Susan J Robertson, Chung W Chow, Philip S Bekhor
BACKGROUND: Infantile hemangioma (IH) with minimal or arrested growth (IH-MAG) is becoming increasingly recognized in the literature. It is important to be aware of their existence, because the correct diagnosis is essential for prognostication and treatment and, in the case of facial segmental lesions, the direction of further investigations if PHACE (posterior fossa abnormalities and other structural brain abnormalities; hemangioma(s) of the cervical facial region; arterial cerebrovascular anomalies; cardiac defects, aortic coarctation, and other aortic abnormalities; eye anomalies) syndrome or Sturge-Weber syndrome is suspected...
November 22, 2016: Pediatric Dermatology
https://www.readbyqxmd.com/read/27871275/rationale-and-design-of-support-a-multi-centre-randomised-controlled-trial-to-compare-three-treatments-cervical-cerclage-cervical-pessary-and-vaginal-progesterone-for-the-prevention-of-preterm-birth-in-women-who-develop-a-short-cervix
#7
Natasha L Hezelgrave, Helena A Watson, Alexandra Ridout, Falak Diab, Paul T Seed, Evonne Chin-Smith, Rachel M Tribe, Andrew H Shennan
BACKGROUND: Clinically, once a woman has been identified as being at risk of spontaneous preterm birth (sPTB) due to a short cervical length, a decision regarding prophylactic treatment must be made. Three interventions have the potential to improve outcomes: cervical cerclage (stitch), vaginal progesterone and cervical pessary. Each has been shown to have similar benefit in reduction of sPTB, but there have been no randomised control trials (RCTs) to compare them. METHODS: This open label multi-centre UK RCT trial, will evaluate whether the three interventions are equally efficacious to prevent premature birth in women who develop a short cervix (<25 mm on transvaginal ultrasound)...
November 21, 2016: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/27865753/development-and-validation-of-the-self-efficacy-regarding-vaginal-birth-scale
#8
Kuei-Hui Chu, Ai-Chieh Chen, Chen-Jei Tai, Shu-Fen Chen, Li-Yin Chien
OBJECTIVES: The purpose of this study was to develop a scale to measure self-efficacy regarding a vaginal birth (SEVB) during pregnancy and to assess its reliability and validity among nulliparous Chinese women. DESIGN: A panel study. SETTING: Five hospitals in Northern Taiwan. PARTICIPANTS: The analysis included 700 (second trimester), 637 (third trimester), and 585 (before birth) women who did not have medical indications for cesarean births at the indicated time points...
November 16, 2016: Journal of Obstetric, Gynecologic, and Neonatal Nursing: JOGNN
https://www.readbyqxmd.com/read/27862265/mode-of-delivery-and-long-term-health-related-quality-of-life-outcomes-a-prospective-population-based-study
#9
Stavros Petrou, Sung Wook Kim, Penny McParland, Elaine M Boyle
BACKGROUND: Relatively little is known about the effects of mode of delivery on long-term health-related quality-of-life outcomes. Furthermore, no previous study has expressed these outcomes in preference-based (utility) metrics. METHODS: The study population comprised 2,161 mothers recruited from a prospective population-based study in the East Midlands of England encompassing live births and stillbirths between 32(+0) and 36(+6) weeks' gestation and a sample of term-born controls...
November 14, 2016: Birth
https://www.readbyqxmd.com/read/27861713/sleep-quality-during-pregnancy-associations-with-depressive-and-anxiety-symptoms
#10
Päivi Polo-Kantola, Linda Aukia, Hasse Karlsson, Linnea Karlsson, E Juulia Paavonen
Sleep disturbances are common during pregnancy, yet underdiagnosed and under-investigated. We evaluated sleep quality during pregnancy and assessed associated factors, especially depressive and anxiety symptoms MATERIALS AND METHODS: A total of 78 healthy pregnant women from the FinnBrain Birth Cohort Study were studied twice prospectively during pregnancy (in mid-pregnancy and late pregnancy). Sleep quality was evaluated by the Basic Nordic Sleep Questionnaire, depressive symptoms by the Edinburgh Postnatal Depression Scale, and anxiety symptoms by the State-Trait Anxiety Inventory RESULTS: Poor general sleep quality, difficulty falling asleep, the number of nocturnal awakenings per night, and too early morning awakenings increased in late pregnancy compared to mid-pregnancy (all p-values < 0...
November 12, 2016: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/27855096/infant-s-sex-birth-control-policy-and-postpartum-well-being-a-prospective-cohort-study-in-shanghai-china
#11
Jing Hua, Liping Zhu, Wenchong Du, Li Du, Ting Luo, Zhuochun Wu
OBJECTIVES: The majority of Chinese families were under either one-child or two-child birth control policy status from 2001 to 2015. We explore the association between an infant's sex and the mother's postpartum well-being, which may be moderated by birth control policy status in China. SETTING AND PARTICIPANTS: We conducted a prospective cohort study in Shanghai City, one of the largest cities in China. A total number of 1730 childbearing women from eight obstetric hospitals across Shanghai were included in the study at baseline, with 1503 women completing the survey 7 days postpartum in 2013...
October 6, 2016: BMJ Open
https://www.readbyqxmd.com/read/27852688/the-role-of-intracytoplasmic-sperm-injection-in-non-male-factor-infertility-in-advanced-maternal-age
#12
Samer Tannus, Weon-Young Son, Ashley Gilman, Grace Younes, Tal Shavit, Michael-Haim Dahan
STUDY QUESTION: Does ICSI improve reproductive outcomes compared with conventional IVF when used for non-male factor infertility in women aged 40 years and over? SUMMARY ANSWER: There is no advantage of ICSI over conventional IVF in women aged 40 years and over when used for non-male factor infertility. WHAT IS KNOWN ALREADY: The use of ICSI has increased dramatically in recent years and is being applied for indications other than male factor infertility...
November 16, 2016: Human Reproduction
https://www.readbyqxmd.com/read/27851773/na%C3%A3-ve-chicks-prefer-hollow-objects
#13
Elisabetta Versace, Jana Schill, Andrea Maria Nencini, Giorgio Vallortigara
Biological predispositions influence approach and avoid responses from the time of birth or hatching. Neonates of species that require parental care (e.g. human babies and chicks of the domestic fowl) are attracted by stimuli associated with animate social partners, such as face-like configurations, biological motion and self-propulsion. The property of being filled is used as a cue of animacy by 8-month-old human infants but it is not known whether this reflects the effect of previous experience. We used chicks of the domestic fowl (Gallus gallus) to investigate whether the property of being filled vs...
2016: PloS One
https://www.readbyqxmd.com/read/27836421/human-milk-is-the-feeding-strategy-to-prevent-necrotizing-enterocolitis
#14
REVIEW
Diana Maffei, Richard J Schanler
Human milk is the preferred diet for preterm infants as it protects against a multitude of NICU challenges, specifically necrotizing enterocolitis. Infants who receive greater than 50% of mother's own milk (MOM) in the 2 weeks after birth have a significantly decreased risk of NEC. An additional factor in the recent declining rates of NEC is the increased utilization of donor human milk (DHM). This creates a bridge until MOM is readily available, thus decreasing the exposure to cow milk protein. Preterm infants are susceptible to NEC due to the immaturity of their gastrointestinal and immune systems...
November 8, 2016: Seminars in Perinatology
https://www.readbyqxmd.com/read/27826324/respiratory-support-with-heated-humidified-high-flow-nasal-cannula-in-preterm-infants
#15
REVIEW
Ga Won Jeon
The incidence of bronchopulmonary dysplasia (BPD) has not decreased over the last decade. The most important way to decrease BPD is by weaning the patient from the ventilator as soon as possible in order to reduce ventilator-induced lung injury that underlies BPD, and by using a noninvasive ventilator (NIV). Use of a heated, humidified, high flow nasal cannula (HHHFNC), which is the most recently introduced NIV mode for respiratory support in preterm infants, is rapidly increasing in many neonatal intensive care units due to the technical ease of use without sealing, and the attending physician's preference compared to other NIV modes...
October 2016: Korean Journal of Pediatrics
https://www.readbyqxmd.com/read/27819116/safety-and-immunogenicity-of-pneumococcal-conjugate-vaccine-in-preterm-infants-a-meta-analysis
#16
Kai Duan, Jin Guo, Ping Lei
OBJECTIVE: To assess the safety and immunogenicity of pneumococcal conjugate vaccine (PCVs) in preterm infants. METHODS: In accordance with the PRISM (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) statement (as of May 2015), a meta-analysis was conducted to evaluate the safety and immunogenicity of PCVs in preterm infants. RESULTS: Ten thousand nine hundred sixty full-term infants and 2131 preterm infants with 344 preterm infants of <2500 g birth weight [low-birth weight (LBW)] were included, and all the subjects were immunized with either PCV-7, PCV-10 or PCV-13 in this random-effects meta-analysis...
November 7, 2016: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/27815732/the-course-of-skull-deformation-from-birth-to-5%C3%A2-years-of-age-a-prospective-cohort-study
#17
Leo A van Vlimmeren, Raoul Hh Engelbert, Maaike Pelsma, Hans Mm Groenewoud, Magda M Boere-Boonekamp, Maria Wg Nijhuis-van der Sanden
: In a continuation of a prospective longitudinal cohort study in a healthy population on the course of skull shape from birth to 24 months, at 5 years of age, 248 children participated in a follow-up assessment using plagiocephalometry (ODDI-oblique diameter difference index, CPI-cranio proportional index). Data from the original study sampled at birth, 7 weeks, 6, 12, and 24 months were used in two linear mixed models. MAIN FINDINGS: (1) if deformational plagiocephaly (ODDI <104%) and/or positional preference at 7 weeks of age are absent, normal skull shape can be predicted at 5 years of age; (2) if positional preference occurs, ODDI is the highest at 7 weeks and decreases to a stable lowest value at 2 and 5 years of age; and (3) regarding brachycephaly, all children showed the highest CPI at 6 months of age with a gradual decrease over time...
November 4, 2016: European Journal of Pediatrics
https://www.readbyqxmd.com/read/27814911/population-based-outcomes-data-for-counseling-at-the-margin-of-gestational-viability
#18
Patrick Myers, Naomi Laventhal, Bree Andrews, Joanne Lagatta, William Meadow
OBJECTIVE: To survey neonatologists as to how many use population-based outcomes data to counsel families before and after the birth of 22- to 25-week preterm infants. STUDY DESIGN: An anonymous online survey was distributed to 1022 neonatologists in the US. Questions addressed the use of population-based outcome data in prenatal and postnatal counseling. RESULTS: Ninety-one percent of neonatologists reported using population-based outcomes data for counseling...
November 1, 2016: Journal of Pediatrics
https://www.readbyqxmd.com/read/27812088/preterm-birth-prevention-post-conization-a-model-of-cervical-length-screening-with-targeted-cerclage
#19
Lindsay M Kindinger, Maria Kyrgiou, David A MacIntyre, Stefano Cacciatore, Angela Yulia, Joanna Cook, Vasso Terzidou, T G Teoh, Phillip R Bennett
Women with a history of excisional treatment (conization) for cervical intra-epithelial neoplasia (CIN) are at increased risk of preterm birth, perinatal morbidity and mortality in subsequent pregnancy. We aimed to develop a screening model to effectively differentiate pregnancies post-conization into low- and high-risk for preterm birth, and to evaluate the impact of suture material on the efficacy of ultrasound indicated cervical cerclage. We analysed longitudinal cervical length (CL) data from 725 pregnant women post-conization attending preterm surveillance clinics at three London university Hospitals over a ten year period (2004-2014)...
2016: PloS One
https://www.readbyqxmd.com/read/27805275/what-s-new-in-atopic-eczema-an-analysis-of-systematic-reviews-published-in-2014-part-1-epidemiology-risk-factors-and-outcomes
#20
REVIEW
S J Hatfield, N K Rogers, A Lloyd-Lavery, D Grindlay, R Barnett, K S Thomas
This review summarizes key findings from nine systematic reviews on atopic eczema (AE) published or first indexed in 2014. It focuses on epidemiology, disease processes and methodological issues. There is reasonable evidence to conclude that high birth weight (> 4000 g) is a risk factor for the development of AE. A lower socioeconomic position is associated with lower prevalence of AE. The effect of exposure to traffic-related air pollution in childhood on the development of AE is uncertain. CD14 polymorphisms do not appear to have an effect in AE...
November 2, 2016: Clinical and Experimental Dermatology
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