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https://www.readbyqxmd.com/read/28230727/analyzing-the-effects-of-uav-mobility-patterns-on-data-collection-in-wireless-sensor-networks
#1
Sarmad Rashed, Mujdat Soyturk
Sensor nodes in a Wireless Sensor Network (WSN) can be dispersed over a remote sensing area (e.g., the regions that are hardly accessed by human beings). In such kinds of networks, datacollectionbecomesoneofthemajorissues. Getting connected to each sensor node and retrieving the information in time introduces new challenges. Mobile sink usage-especially Unmanned Aerial Vehicles (UAVs)-is the most convenient approach to covering the area and accessing each sensor node in such a large-scale WSN. However, the operation of the UAV depends on some parameters, such as endurance time, altitude, speed, radio type in use, and the path...
February 20, 2017: Sensors
https://www.readbyqxmd.com/read/28229461/how-different-is-a-3d-printed-replica-from-a-conspecific-in-the-eyes-of-a-zebrafish
#2
Tommaso Ruberto, Giovanni Polverino, Maurizio Porfiri
Robotics is emerging as a promising tool for aiding research on animal behavior. The possibility of generating customizable, controllable, and standardized robotic stimuli has been demonstrated through a number of behavioral assays, involving vertebrates and invertebrates. However, the specific appraisal of the nature of robotic stimuli is currently lacking. Here, we attempt to evaluate this aspect in zebrafish, through a within-subject design in which experimental subjects are faced with three experimental conditions...
February 22, 2017: Journal of the Experimental Analysis of Behavior
https://www.readbyqxmd.com/read/28228078/nanocarriers-mediated-topical-drug-delivery-for-psoriasis-treatment
#3
Sevgi Güngör, Meriem Rezigue
BACKGROUND: Psoriasis is a chronic autoimmune inflammatory skin disease affecting 2 to 3% of people worldwide. Topical therapy as first option in the management of psoriasis is an attractive strategy by delivering drugs efficiently into target sites of disease, minimizing systemic side effects of drugs and ensuring high patient compliance. However, the delivery of antipsoriatic agents via conventional topical formulations is limited due to their poor percutaneous penetration and targeting into deeper layers of the skin...
February 22, 2017: Current Drug Metabolism
https://www.readbyqxmd.com/read/28227971/a-feature-exploration-methodology-for-learning-based-cuffless-blood-pressure-measurement-using-photoplethysmography
#4
Kefeng Duan, Zhiliang Qian, Mohamed Atef, Guoxing Wang, Kefeng Duan, Zhiliang Qian, Mohamed Atef, Guoxing Wang, Zhiliang Qian, Kefeng Duan, Guoxing Wang, Mohamed Atef
In this work, we propose a feature exploration method for learning-based cuffless blood pressure measurement. More specifically, to efficiently explore a large feature space from the photoplethysmography signal, we have applied several analytical techniques, including random error elimination, adaptive outlier removal, maximum information coefficient and Pearson's correlation coefficient based feature assessment methods. We evaluate fifty-seven possible feature candidates and propose three separate feature sets with each containing eleven features to predict the systolic blood pressure (SBP), diastolic blood pressure (DBP) and mean blood pressure (MBP), respectively...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227675/investigating-an-alternative-ring-design-of-transducer-arrays-for-tumor-treating-fields-ttfields
#5
Mario Macedo, Cornelia Wenger, Ricardo Salvador, Sofia R Fernandes, Pedro C Miranda, Mario Macedo, Cornelia Wenger, Ricardo Salvador, Sofia R Fernandes, Pedro C Miranda, Sofia R Fernandes, Pedro C Miranda, Cornelia Wenger, Ricardo Salvador, Mario Macedo
Tumor treating fields (TTFields) is a therapy that inhibits cell proliferation and has been approved by the U.S Food and Drug Administration (FDA) for the treatment of Glioblastoma Multiforme. This anti-mitotic technique works non-invasively and regionally, and is associated with less toxicity and a better quality of life. Currently a device called Optune™ is clinically used which works with two perpendicular and alternating array pairs each consisting of 3×3 transducers. The aim of this study is to investigate a theoretical alternative array design which consists of two rings of 16 transducers and thus permits various field directions...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227401/mesh-resolution-impacts-the-accuracy-of-inverse-and-forward-ecg-problems
#6
Bing Yao, Shenli Pei, Hui Yang, Bing Yao, Shenli Pei, Hui Yang, Hui Yang, Bing Yao, Shenli Pei
Electrocardiographic imaging (ECGI) has become an important medical diagnosis tool that assists scientists to noninvasively investigate cardiac electric activity. Many previous works have studied the inverse and forward ECG problems to understand how to reconstruct the cardiac electric activity from the body potential distribution. However, the inverse ECG problem is highly ill-conditioned and very sensitive to errors and noises. Thus, there is a need to study the sensitivity of inverse and forward ECG problems...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227223/bringing-hemodynamic-simulations-closer-to-the-clinics-a-cfd-prototype-study-for-intracranial-aneurysms
#7
Philipp Berg, Samuel Vos, Mathias Becker, Steffen Serowy, Thomas Redel, Gabor Janiga, Martin Skalej, Oliver Beuing, Philipp Berg, Samuel Vos, Mathias Becker, Steffen Serowy, Thomas Redel, Gabor Janiga, Martin Skalej, Oliver Beuing, Steffen Serowy, Martin Skalej, Oliver Beuing, Thomas Redel, Philipp Berg, Gabor Janiga, Mathias Becker
Computational Fluid Dynamics enables the investigation of patient-specific hemodynamics for rupture predictions and treatment support of intracranial aneurysms. However, due to numerous simplifications to decrease the computations effort, clinical applicability is limited until now. To overcome this situation a clinical research software prototype was tested that can be easily operated by attending physicians. In order to evaluate the accuracy of this prototype, four patient-specific intracranial aneurysms were investigated using four different spatial resolutions...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227161/in-to-out-body-path-loss-for-wireless-radio-frequency-capsule-endoscopy-in-a-human-body
#8
G Vermeeren, E Tanghe, A Thielens, L Martens, W Joseph, G Vermeeren, E Tanghe, A Thielens, L Martens, W Joseph, E Tanghe, A Thielens, L Martens, G Vermeeren, W Joseph
Physical-layer characterization is important for design of in-to-out body communication for wireless body area networks (WBANs). This paper numerically investigates the path loss of an in-to-out body radio frequency (RF) wireless link between an endoscopy capsule and a receiver outside the body using a 3D electromagnetic solver. A spiral antenna in the endoscopy capsule is tuned to operate in the Medical Implant Communication Service (MICS) band at 402 MHz, accounting for the properties of the human body. The influence of misalignment, rotation of the capsule, and human body model are investigated...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226993/first-steps-to-creating-a-platform-for-high-throughput-simulation-of-ttfields
#9
Hadas Sara Hershkovich, Zeev Bomzon, Cornelia Wenger, Noa Urman, Aafia Chaudhry, Dario Garcia-Carracedo, Eilon D Kirson, Uri Weinberg, Yoram Wassermann, Yoram Palti, Hadas Sara Hershkovich, Zeev Bomzon, Cornelia Wenger, Noa Urman, Aafia Chaudhry, Dario Garcia-Carracedo, Eilon D Kirson, Uri Weinberg, Yoram Wassermann, Yoram Palti, Yoram Wassermann, Cornelia Wenger, Uri Weinberg, Hadas Sara Hershkovich, Zeev Bomzon, Eilon D Kirson, Dario Garcia-Carracedo, Yoram Palti, Noa Urman, Aafia Chaudhry
Tumor Treating Fields (TTFields) are low intensity alternating electric fields in the 100-500 KHz frequency range that are known to have an anti-mitotic effect on cancerous cells. In the USA, TTFields are approved by the Food and Drug Administration (FDA) for the treatment of glioblastoma (GBM) in both the newly diagnosed and recurrent settings. Optimizing treatment with TTFields requires a deep understanding of how TTFields distribute within the brain. To address this issue, simulations using realistic head models have been performed...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226856/evaluation-of-the-electric-field-in-the-brain-during-transcranial-direct-current-stimulation-a-sensitivity-analysis
#10
Laura Santos, Miguel Martinho, Ricardo Salvador, Cornelia Wenger, Sofia R Fernandes, Oscar Ripolles, Giulio Ruffini, Pedro C Miranda, Laura Santos, Miguel Martinho, Ricardo Salvador, Cornelia Wenger, Sofia R Fernandes, Oscar Ripolles, Giulio Ruffini, Pedro C Miranda, Laura Santos, Miguel Martinho, Cornelia Wenger, Ricardo Salvador, Oscar Ripolles, Giulio Ruffini, Sofia R Fernandes, Pedro C Miranda
The use of computational modeling studies accounts currently for the best approach to predict the electric field (E-field) distribution in transcranial direct current stimulation. As with any model, the values attributed to the physical properties, namely the electrical conductivity of the tissues, affect the predicted E-field distribution. A wide range of values for the conductivity of most tissues is reported in the literature. In this work, we used the finite element method to compute the E-field induced in a realistic human head model for two electrode montages targeting the left dorso-lateral prefrontal cortex (DLPFC)...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28225799/sf-6d-utility-values-for-the-better-and-worse-seeing-eye-for-health-states-based-on-the-snellen-equivalent-in-patients-with-age-related-macular-degeneration
#11
Martijn S Visser, Sankha Amarakoon, Tom Missotten, Reinier Timman, Jan J Busschbach
OBJECTIVE: Economic evaluations in wet age-related macular degeneration (ARMD) is hampered as often utility values for solely one eye are used, mostly the better-seeing eye (BSE). Moreover, frequently chosen methods rely on patient values and/or disease specific measures, while economic evaluations prefer generic quality of life (QoL) measures based on societal preferences. The generic QoL utility instrument EQ-5D has shown to be insensitive for differences in visual acuity. The aim of this study was therefore to provide societal utility values, using the generic SF-6D, for health states acknowledging both BSE and worse-seeing eye (WSE)...
2017: PloS One
https://www.readbyqxmd.com/read/28221057/-understanding-the-neural-basis-of-cognitive-bias-modification-as-a-clinical-treatment-for-depression-correction-to-eguchi-et-al-2016
#12
(no author information available yet)
: Reports an error in "Understanding the neural basis of cognitive bias modification as a clinical treatment for depression" by Akihiro Eguchi, Daniel Walters, Nele Peerenboom, Hannah Dury, Elaine Fox and Simon Stringer (Journal of Consulting and Clinical Psychology, Advanced Online Publication, Dec 19, 2016, np). In the article, there was an error in the Discussion section's first paragraph for Implications and Future Work. The in-text reference citation for Penton-Voak et al. (2013) was incorrectly listed as "Blumenfeld, Preminger, Sagi, and Tsodyks (2006)"...
March 2017: Journal of Consulting and Clinical Psychology
https://www.readbyqxmd.com/read/28219685/development-of-a-chronic-disease-management-program-for-stroke-survivors-using-intervention-mapping-the-stroke-coach
#13
Brodie M Sakakibara, Scott A Lear, Susan I Barr, Oscar Benavente, Charlie H Goldsmith, Noah D Silverberg, Jennifer Yao, Janice J Eng
OBJECTIVE: To describe the systematic development of the Stroke Coach, a theory- and evidence-based intervention to improve control of lifestyle behaviour risk factors in stroke patients. DESIGN: Intervention development. SETTING: Community. PARTICIPANTS: Individuals who have had a stroke. INTERVENTION: We used Intervention Mapping to guide the development of the Stroke Coach. Intervention Mapping is a systematic process used for intervention development and comprised of steps that progress from the integration of theory and evidence to the organization of realistic strategies to facilitate the development of a practical intervention supported by empirical evidence...
February 17, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28218888/using-clinical-signs-and-symptoms-for-medical-management-of-radiation-casualties-2015-nato-exercise
#14
H Dörr, M Abend, W F Blakely, D L Bolduc, D Boozer, T Costeira, T Dant, A De Amicis, S De Sanctis, M Dondey, M Drouet, F Entine, S Francois, G Gagna, N Guitard, F Hérodin, M Hoefer, A Lamkowski, G La Sala, F Lista, P Loiacono, M Majewski, P Martigne, D Métivier, X Michel, J Pateux, J Pejchal, G Reeves, D Riccobono, Z Sinkorova, L Soyez, D Stricklin, A Tichy, M Valente, C R Woodruff, L Zarybnicka, M Port
The utility of early-phase (≤5 days) radiation-induced clinical signs and symptoms (e.g., vomiting, diarrhea, erythema and changes in blood cell counts) was examined for the prediction of later occurring acute radiation syndrome (ARS) severity and the development of medical management strategies. Medical treatment protocols for radiation accident victims (METREPOL) was used to grade ARS severities, which were assigned response categories (RCs). Data on individuals (n = 191) with mild (RC1, n = 45), moderate (RC2, n = 19), severe (RC3, n = 20) and fatal (RC4, n = 18) ARS, as well as nonexposed individuals (RC0, n = 89) were generated using either METREPOL (n = 167) or the system for evaluation and archiving of radiation accidents based on case histories (SEARCH) database (n = 24), the latter comprised of real-case descriptions...
February 20, 2017: Radiation Research
https://www.readbyqxmd.com/read/28214431/simulation-in-undergraduate-paediatric-nursing-curriculum-evaluation-of-a-complex-ward-for-a-day-education-program
#15
Andree S Gamble
Simulation in health education has been shown to increase confidence, psychomotor and professional skills, and thus positively impact on student preparedness for clinical placement. It is recognised as a valuable tool to expose and engage students in realistic patient care encounters without the potential to cause patient harm. Although inherent challenges exist in the development and implementation of simulation, variability in clinical placement time, availability and quality dictates the need to provide students with learning opportunities they may otherwise not experience...
February 4, 2017: Nurse Education in Practice
https://www.readbyqxmd.com/read/28212703/optimal-shielding-thickness-for-galactic-cosmic-ray-environments
#16
Tony C Slaba, Amir A Bahadori, Brandon D Reddell, Robert C Singleterry, Martha S Clowdsley, Steve R Blattnig
Models have been extensively used in the past to evaluate and develop material optimization and shield design strategies for astronauts exposed to galactic cosmic rays (GCR) on long duration missions. A persistent conclusion from many of these studies was that passive shielding strategies are inefficient at reducing astronaut exposure levels and the mass required to significantly reduce the exposure is infeasible, given launch and associated cost constraints. An important assumption of this paradigm is that adding shielding mass does not substantially increase astronaut exposure levels...
February 2017: Life Sciences in Space Research
https://www.readbyqxmd.com/read/28209077/using-gp-trainees-as-role-players-as-a-teaching-training-tool-for-established-gp-trainers
#17
Kim Emerson, Penny Moore, Jill Edwards
This work aimed to evaluate the effectiveness of using GP trainees in place of professional actors, to role-play trainees with 'difficulties' or various challenging characteristics, as an educational tool for skills development of experienced GP trainers. The context was a residential experienced GP trainers' course and the role players were local ST3 GP trainees. Professional actors have been used for this purpose for many years in medical education at all levels, particularly in teaching communication and consultation skills in the Thames Valley area of the UK...
February 16, 2017: Education for Primary Care
https://www.readbyqxmd.com/read/28208231/fast-left-ventricle-tracking-using-localized-anatomical-affine-optical-flow
#18
Sandro Queirós, João L Vilaça, Pedro Morais, Jaime C Fonseca, Jan D'hooge, Daniel Barbosa
In daily clinical cardiology practice, left ventricle (LV) global and regional function assessment is crucial for disease diagnosis, therapy selection and patient follow-up. Currently, this is still a time-consuming task, spending valuable human resources. In this work, a novel fast methodology for automatic LV tracking is proposed based on localized anatomically constrained affine optical flow. This novel method can be combined to previously proposed segmentation frameworks or manually delineated surfaces at an initial frame to obtain fully delineated datasets and, thus, assess both global and regional myocardial function...
February 16, 2017: International Journal for Numerical Methods in Biomedical Engineering
https://www.readbyqxmd.com/read/28208209/the-emergence-of-tnik-inhibitors-in-cancer-therapeutics
#19
REVIEW
Tesshi Yamada, Mari Masuda
The outcome of patients with metastatic colorectal cancer remains unsatisfactory. To improve patient prognosis, it will be necessary to identify new drug targets based on molecules that are essential for colorectal carcinogenesis, and to develop therapeutics that target such molecules. The great majority of colorectal cancers (>90%) have mutations in at least one Wnt signaling pathway gene. Aberrant activation of Wnt signaling is a major force driving colorectal carcinogenesis. Several therapeutics targeting Wnt pathway molecules, including porcupine, frizzled receptors, and tankyrases, have been developed, but none of them have yet been incorporated into clinical practice...
February 16, 2017: Cancer Science
https://www.readbyqxmd.com/read/28205641/the-tiered-evaluation-of-the-effects-of-transgenic-cry1c-rice-on-cyrtorhinus-lividipennis-a-main-predator-of-nilaparvata-lugens
#20
Yu Han, Fugang Ma, Muhammad Nawaz, Yu Wang, Wanlun Cai, Jing Zhao, Yueping He, Hongxia Hua, Yulan Zou
T1C-19, a newly developed transgenic cry1C rice line, expresses cry1C under the control of the maize ubiquitin promoter, and is highly resistant to lepidopteran pests of rice. Cyrtorhinus lividipennis is the major predator of the eggs and young nymphs of Nilaparvata lugens, which is the main non-target sap-sucking insect pest of Bt rice. C. lividipennis may be exposed to Cry1C protein, thus biosafety evaluations of transgenic cry1C rice on C. lividipennis should be conducted before the commercialization of T1C-19...
February 16, 2017: Scientific Reports
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