keyword
MENU ▼
Read by QxMD icon Read
search

Adaptive design

keyword
https://www.readbyqxmd.com/read/28214583/remediation-of-fluoride-from-drinking-water-using-magnetic-iron-oxide-coated-hydrotalcite-chitosan-composite
#1
Kalimuthu Pandi, Soodamani Periyasamy, Natrayasamy Viswanathan
The present study was performed to examine the probability of magnetic iron oxide fabricated hydrotalcite/chitosan (Fe3O4@HTCS) composite for the removal of excess fluoride content from drinking water. The developed Fe3O4@HTCS composite not only demonstrate the good separation ability but also display an extreme enhanced defluoridation capacity (DC) when compared to other base components and composite. The DCs of Fe3O4@HTCS composite, Fe3O4@HT composite, Fe3O4, HT and CS was found to be 5032, 3041, 1050, 1030 and 52 mgF(-)/kg respectively...
February 15, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28214078/the-optimize-heart-failure-care-program-initial-lessons-from-global-implementation
#2
Martin R Cowie, Yuri M Lopatin, Clara Saldarriaga, Cândida Fonseca, David Sim, Jose Antonio Magaña, Denilson Albuquerque, Marcelo Trivi, Gustavo Moncada, Baldomero A González Castillo, Mario Osvaldo Speranza Sánchez, Edward Chung
Hospitalization for heart failure (HF) places a major burden on healthcare services worldwide, and is a strong predictor of increased mortality especially in the first three months after discharge. Though undesirable, hospitalization is an opportunity to optimize HF therapy and advise clinicians and patients about the importance of continued adherence to HF medication and regular monitoring. The Optimize Heart Failure Care Program (www.optimize-hf.com), which has been implemented in 45 countries, is designed to improve outcomes following HF hospitalization through inexpensive initiatives to improve prescription of appropriate drug therapies, patient education and engagement, and post-discharge planning...
February 12, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28213330/drug-discovery-strategies-in-the-field-of-tumor-energy-metabolism-limitations-by-metabolic-flexibility-and-metabolic-resistance-to-chemotherapy
#3
REVIEW
N D Amoedo, E Obre, R Rossignol
The search for new drugs capable of blocking the metabolic vulnerabilities of human tumors has now entered the clinical evaluation stage, but several projects already failed in phase I or phase II. In particular, very promising in vitro studies could not be translated in vivo at preclinical stage and beyond. This was the case for most glycolysis inhibitors that demonstrated systemic toxicity. A more recent example is the inhibition of glutamine catabolism in lung adenocarcinoma that failed in vivo despite a strong addiction of several cancer cell lines to glutamine in vitro...
February 14, 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/28212606/the-implementation-of-health-promotion-in-primary-and-community-care-a-qualitative-analysis-of-the-prescribe-vida-saludable-strategy
#4
Catalina Martinez, Gonzalo Bacigalupe, Josep M Cortada, Gonzalo Grandes, Alvaro Sanchez, Haizea Pombo, Paola Bully
BACKGROUND: The impact of lifestyle on health is undeniable and effective healthy lifestyle promotion interventions do exist. However, this is not a fundamental part of routine primary care clinical practice. We describe factors that determine changes in performance of primary health care centers involved in piloting the health promotion innovation 'Prescribe Vida Saludable' (PVS) phase II. METHODS: We engaged four primary health care centers of the Basque Healthcare Service in an action research project aimed at changing preventive health practices...
February 17, 2017: BMC Family Practice
https://www.readbyqxmd.com/read/28212392/what-s-in-a-game-a-systems-approach-to-enhancing-performance-analysis-in-football
#5
Scott McLean, Paul M Salmon, Adam D Gorman, Gemma J M Read, Colin Solomon
PURPOSE: Performance analysis (PA) in football is considered to be an integral component of understanding the requirements for optimal performance. Despite vast amounts of research in this area key gaps remain, including what comprises PA in football, and methods to minimise research-practitioner gaps. The aim of this study was to develop a model of the football match system in order to better describe and understand the components of football performance. Such a model could inform the design of new PA methods...
2017: PloS One
https://www.readbyqxmd.com/read/28212196/prison-nursing-formation-of-a-stable-professional-identity
#6
Khurshid Choudhry, David Armstrong, Alexandru Dregan
AIM: The aim of this study was to analyze how working within prison environments can influence the self-identity and professional identity of nurses. BACKGROUND: The prison environment can be a difficult environment for nurses to deliver care within, with nurses having to carry out activities that seem to go against their professional role, while at the same time providing care to prisoners who have greater health needs than the general population. There is a lack of theoretical consideration of how prison nurses carry out their role in the face of such challenges...
January 2017: Journal of Forensic Nursing
https://www.readbyqxmd.com/read/28212089/streammap-smooth-dynamic-visualization-of-high-density-streaming-points
#7
Chenhui Li, George Baciu, Han Yu
Interactive visualization of streaming points for real-time scatterplots and linear blending of correlation patterns is increasingly becoming the dominant mode of visual analytics for both big data and streaming data from active sensors and broadcasting media. To better visualize and interact with inter-stream patterns, it is generally necessary to smooth out gaps or distortions in the streaming data. Previous approaches either animate the points directly or present a sampled static heatmap. We propose a new approach, called StreamMap, to smoothly blend high-density streaming points and create a visual flow that emphasizes the density pattern distributions...
February 13, 2017: IEEE Transactions on Visualization and Computer Graphics
https://www.readbyqxmd.com/read/28212072/neural-network-based-solutions-for-stochastic-optimal-control-using-path-integrals
#8
Karthikeyan Rajagopal, Sivasubramanya Nadar Balakrishnan, Jerome R Busemeyer
In this paper, an offline approximate dynamic programming approach using neural networks is proposed for solving a class of finite horizon stochastic optimal control problems. There are two approaches available in the literature, one based on stochastic maximum principle (SMP) formalism and the other based on solving the stochastic Hamilton-Jacobi-Bellman (HJB) equation. However, in the presence of noise, the SMP formalism becomes complex and results in having to solve a couple of backward stochastic differential equations...
March 2017: IEEE Transactions on Neural Networks and Learning Systems
https://www.readbyqxmd.com/read/28211944/bayesian-response-adaptive-designs-for-basket-trials
#9
Steffen Ventz, William T Barry, Giovanni Parmigiani, Lorenzo Trippa
We develop a general class of response-adaptive Bayesian designs using hierarchical models, and provide open source software to implement them. Our work is motivated by recent master protocols in oncology, where several treatments are investigated simultaneously in one or multiple disease types, and treatment efficacy is expected to vary across biomarker-defined subpopulations. Adaptive trials such as I-SPY-2 (Barker et al., 2009) and BATTLE (Zhou et al., 2008) are special cases within our framework. We discuss the application of our adaptive scheme to two distinct research goals...
February 17, 2017: Biometrics
https://www.readbyqxmd.com/read/28211056/targeted-mass-media-interventions-promoting-healthy-behaviours-to-reduce-risk-of-non-communicable-diseases-in-adult-ethnic-minorities
#10
REVIEW
Annhild Mosdøl, Ingeborg B Lidal, Gyri H Straumann, Gunn E Vist
BACKGROUND: Physical activity, a balanced diet, avoidance of tobacco exposure, and limited alcohol consumption may reduce morbidity and mortality from non-communicable diseases (NCDs). Mass media interventions are commonly used to encourage healthier behaviours in population groups. It is unclear whether targeted mass media interventions for ethnic minority groups are more or less effective in changing behaviours than those developed for the general population. OBJECTIVES: To determine the effects of mass media interventions targeting adult ethnic minorities with messages about physical activity, dietary patterns, tobacco use or alcohol consumption to reduce the risk of NCDs...
February 17, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28210241/outer-membrane-proteins-form-specific-patterns-in-antibiotic-resistant-edwardsiella-tarda
#11
Bo Peng, Chao Wang, Hui Li, Yu-Bin Su, Jin-Zhou Ye, Man-Jun Yang, Ming Jiang, Xuan-Xian Peng
Outer membrane proteins of Gram-negative bacteria play key roles in antibiotic resistance. However, it is unknown whether outer membrane proteins that respond to antibiotics behave in a specific manner. The present study specifically investigated the differentially expressed outer membrane proteins of an antibiotic-resistant bacterium, Edwardsiella tarda, a Gram-negative pathogen that can lead to unnecessary mass medication of antimicrobials and consequently resistance development in aquaculture and a spectrum of intestinal and extraintestinal diseases in humans...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28208289/atmospheric-pressure-vaporization-mechanism-for-coupling-a-liquid-phase-with-electron-ionization-mass-spectrometry
#12
Veronica Termopoli, Giorgio Famiglini, Pierangela Palma, Maurizio Piergiovanni, Achille Cappiello
A novel liquid chromatography-mass spectrometry (LC-MS) interfacing concept is presented and discussed. The new interface, called liquid-EI (LEI), is based on electron ionization (EI) but, differently from any previous attempt, the vaporization of solutes and mobile phase takes place at atmospheric pressure into a specifically designed region, called "vaporization microchannel", before entering the high-vacuum ion source. The interface is completely independent from the rest of the instrumentation and can be adapted to any gas chromatography/mass spectrometry (GC/MS) system, as an add-on for a rapid LC-MS conversion...
February 7, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28207383/person-re-identification-by-camera-correlation-aware-feature-augmentation
#13
Ying-Cong Chen, Xiatian Zhu, Wei-Shi Zheng, Jian-Huang Lai
The challenge of person re-identification (re-id) is to match individual images of the same person captured by different non-overlapping camera views against significant and unknown cross-view feature distortion. While a large number of distance metric/subspace learning models have been developed for re-id, the cross-view transformations they learned are view-generic and thus potentially less effective in quantifying the feature distortion inherent to each camera view. Learning view-specific feature transformations for re-id (i...
February 9, 2017: IEEE Transactions on Pattern Analysis and Machine Intelligence
https://www.readbyqxmd.com/read/28207326/micro-rna-146a-but-not-irak1-is-associated-with-rheumatoid-arthritis-in-the-tunisian-population
#14
Hana Ben Hassine, Asma Boumiza, Rim Sghiri, Khadija Baccouche, Imen Boussaid, Ahlem Atig, Zahid Shakoor, Elyes Bouajina, Ramzi Zemni
BACKGROUND: Rheumatoid arthritis (RA) is characterized by the production of an array of proinflammatory cytokines through the nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) signaling pathway. Interleukin-1 receptor (IL-1R) and Toll-like receptors contain a common cytoplasmic motif the Toll/IL-1R (TIR) homology domain. This motif is required for NF-κB activation. IL-1R-associated kinase 1 (IRAK1) is a key adapter molecule recruited during the signaling cascade of the TIR...
February 2017: Genetic Testing and Molecular Biomarkers
https://www.readbyqxmd.com/read/28206996/the-quest-for-sustained-multiple-morbidity-reduction-in-very-low-birth-weight-infants-the-antifragility-project
#15
J W Kaempf, N M Schmidt, S Rogers, C Novack, M Friant, L Wang, N Tipping
OBJECTIVE: Can a comprehensive, explicitly directive evidence-based guideline for all therapies that might affect the major morbidities of very low-birth-weight (VLBW) infants help a neonatal intensive care unit (NICU) further improve generally favorable morbidity rates? Can Antifragility principles of provider adaptive growth from stressors, enhanced infant risk assessment and adherence to effective therapies minimize unproven treatments and reduce all morbidities? STUDY DESIGN: Prospectively planned observational trial in VLBW infants: control group born October 2011 to September 2013 and study group October 2013 to September 2015...
February 16, 2017: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/28205556/hrgfish-a-database-of-hypoxia-responsive-genes-in-fishes
#16
Iliyas Rashid, Naresh Sahebrao Nagpure, Prachi Srivastava, Ravindra Kumar, Ajey Kumar Pathak, Mahender Singh, Basdeo Kushwaha
Several studies have highlighted the changes in the gene expression due to the hypoxia response in fishes, but the systematic organization of the information and the analytical platform for such genes are lacking. In the present study, an attempt was made to develop a database of hypoxia responsive genes in fishes (HRGFish), integrated with analytical tools, using LAMPP technology. Genes reported in hypoxia response for fishes were compiled through literature survey and the database presently covers 818 gene sequences and 35 gene types from 38 fishes...
February 13, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28205321/an-investigative-graduate-laboratory-course-for-teaching-modern-dna-techniques
#17
Alexandre de Lencastre, A Thomas Torello, Lani C Keller
This graduate-level DNA methods laboratory course is designed to model a discovery-based research project and engages students in both traditional DNA analysis methods and modern recombinant DNA cloning techniques. In the first part of the course, students clone the Drosophila ortholog of a human disease gene of their choosing using Gateway(®) cloning. In the second part of the course, students examine the expression of their gene of interest in human cell lines by reverse transcription PCR and learn how to analyze data from quantitative reverse transcription PCR (qRT-PCR) experiments...
February 16, 2017: Biochemistry and Molecular Biology Education
https://www.readbyqxmd.com/read/28205296/effects-of-mindfulness-based-intervention-to-improve-task-performance-for-children-with-intellectual-disabilities
#18
Jeongil Kim, Miyoung Kwon
BACKGROUND: Task performance is a critical factor for learning in individuals with intellectual disabilities. This study aimed to examine mindfulness-based intervention (MBI) to improve task performance for children with intellectual disability (ID). METHODS: Three elementary school children with ID participated in the study. A multiple baseline design across subjects was used. The intervention was consisted of "understanding the necessary concept of mindfulness, practice of awareness and attention, and practice focusing on mindful behaviours...
February 16, 2017: Journal of Applied Research in Intellectual Disabilities: JARID
https://www.readbyqxmd.com/read/28203643/establishing-elements-of-a-synthetic-biology-platform-for-vaccinia-virus-production-biobrick%C3%A2-design-serum-free-virus-production-and-microcarrier-based-cultivation-of-cv-1-cells
#19
Shuchang Liu, Ludmila Ruban, Yaohe Wang, Yuhong Zhou, Darren N Nesbeth
Vaccinia virus (VACV) is an established vector for vaccination and is beginning to prove effective as an oncolytic agent. Industrial production of VACV stands to benefit in future from advances made by synthetic biology in genome engineering and standardisation. The CV-1 cell line can be used for VACV propagation and has been used extensively with the CRISPR/Cas9 system for making precise edits of the VACV genome. Here we take first steps toward establishing a scalable synthetic biology platform for VACV production with CV-1 cells featuring standardised biological tools and serum free cell cultivation...
February 2017: Heliyon
https://www.readbyqxmd.com/read/28203141/evolutionary-algorithm-based-feature-optimization-for-multi-channel-eeg-classification
#20
Yubo Wang, Kalyana C Veluvolu
The most BCI systems that rely on EEG signals employ Fourier based methods for time-frequency decomposition for feature extraction. The band-limited multiple Fourier linear combiner is well-suited for such band-limited signals due to its real-time applicability. Despite the improved performance of these techniques in two channel settings, its application in multiple-channel EEG is not straightforward and challenging. As more channels are available, a spatial filter will be required to eliminate the noise and preserve the required useful information...
2017: Frontiers in Neuroscience
keyword
keyword
76662
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"