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Bayes theorem

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https://www.readbyqxmd.com/read/28537096/bayes-theorem-and-its-application-to-cardiovascular-nursing
#1
David R Thompson, Colin R Martin
No abstract text is available yet for this article.
May 1, 2017: European Journal of Cardiovascular Nursing
https://www.readbyqxmd.com/read/28521616/a-10-gene-classifier-for-indeterminate-thyroid-nodules-development-and-multicenter-accuracy-study
#2
Hernan E Gonzalez, Jose R Martínez, Sergio Vargas, Antonieta Solar, Loreto Pamela Véliz, Francisco Cruz, Tatiana Arias, Soledad Loyola, Eleonora Horvath, Hernán Tala, Eufrosina Traipe, Manuel Meneses, Luis Marin, Nelson Wohllk, Rene Eduardo Diaz, Jesús Véliz, Pedro Pineda, Patricia Arroyo, Natalia Mena, Milagros Bracamonte, Giovanna Miranda, Elsa Bruce, Soledad Urra
BACKGROUND: In most of the world, diagnostic surgery remains as the most frequent approach for indeterminate thyroid cytology. Although several molecular tests are available for central-lab testing in the US, there are no available kits for local laboratory testing. The aim of this study was to develop a prototype in-vitro diagnostic (IVD) gene classifier for diagnosis of indeterminate thyroid cytology. METHODS: In a first stage, the expression of 18 genes was determined by qPCR in a broad histopathological spectrum of fresh tissue biopsies (114)...
May 18, 2017: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/28508528/competing-risks-model-in-screening-for-preeclampsia-in-twin-pregnancies-by-maternal-characteristics-and-medical-history
#3
Carla Francisco, David Wright, Zsófia Benkő, Argyro Syngelaki, Kypros H Nicolaides
OBJECTIVE: A survival-time regression model for the gestational age at delivery with preeclampsia (PE) in singleton pregnancies using maternal demographic characteristics and medical history was previously reported. The objective of this paper is to extend this model for dichorionic (DC) and monochorionic (MC) twin pregnancies. METHODS: The study population included 1,789 DC and 430 MC twin pregnancies and 93,297 singleton pregnancies. A survival-time model for the gestational age at delivery with PE was developed from variables of maternal characteristics and history...
May 15, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28485630/estimation-of-diagnostic-performance-of-dementia-screening-tests-mini-mental-state-examination-mini-cog-clock-drawing-test-and-ascertain-dementia-8-questionnaire
#4
Li Yang, Jing Yan, Xiaoqing Jin, Yu Jin, Wei Yu, Shanhu Xu, Haibin Wu, Ying Xu, Caixia Liu
OBJECTIVE: Dementia is one of the leading causes of dependence in the elderly. This study was conducted to estimate diagnostic performance of dementia screening tests including Mini-Mental State Examination (MMSE), Mini-Cog, Clock Drawing Test (CDT) and Ascertain Dementia 8 questionnaire (AD8) by Bayesian models. METHOD: A total of 2015 participants aged 65 years or more in eastern China were enrolled. The four screening tests were administered and scored by specifically trained psychiatrists...
May 9, 2017: Aging & Mental Health
https://www.readbyqxmd.com/read/28435311/application-of-bayesian-decision-making-to-laboratory-testing-for-lyme-disease-and-comparison-with-testing-for-hiv
#5
Michael J Cook, Basant K Puri
In this study, Bayes' theorem was used to determine the probability of a patient having Lyme disease (LD), given a positive test result obtained using commercial test kits in clinically diagnosed patients. In addition, an algorithm was developed to extend the theorem to the two-tier test methodology. Using a disease prevalence of 5%-75% in samples sent for testing by clinicians, evaluated with a C6 peptide enzyme-linked immunosorbent assay (ELISA), the probability of infection given a positive test ranged from 26...
2017: International Journal of General Medicine
https://www.readbyqxmd.com/read/28408468/avoidance-of-voiding-cystourethrography-in-infants-younger-than-3-months-with-escherichia-coli-urinary-tract-infection-and-normal-renal-ultrasound
#6
Jean-Yves Pauchard, Hassib Chehade, Chafika Zohra Kies, Eric Girardin, Francois Cachat, Mario Gehri
BACKGROUND AND OBJECTIVE: Urinary tract infection (UTI) represents the most common bacterial infection in infants, and its prevalence increases with the presence of high-grade vesicoureteral reflux (VUR). However, voiding cystourethrography (VCUG) is invasive, and its indication in infants <3 months is not yet defined. This study aims to investigate, in infants aged 0-3 months, if the presence of Escherichia coli versus non-E. coli bacteria and/or normal or abnormal renal ultrasound (US) could avoid the use of VCUG...
April 13, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28386994/a-comparison-of-bayesian-and-monte-carlo-sensitivity-analysis-for-unmeasured-confounding
#7
Lawrence C McCandless, Paul Gustafson
Bias from unmeasured confounding is a persistent concern in observational studies, and sensitivity analysis has been proposed as a solution. In the recent years, probabilistic sensitivity analysis using either Monte Carlo sensitivity analysis (MCSA) or Bayesian sensitivity analysis (BSA) has emerged as a practical analytic strategy when there are multiple bias parameters inputs. BSA uses Bayes theorem to formally combine evidence from the prior distribution and the data. In contrast, MCSA samples bias parameters directly from the prior distribution...
April 6, 2017: Statistics in Medicine
https://www.readbyqxmd.com/read/28384335/data-processing-of-qualitative-results-from-an-interlaboratory-comparison-for-the-detection-of-flavescence-dor%C3%A3-e-phytoplasma-how-the-use-of-statistics-can-improve-the-reliability-of-the-method-validation-process-in-plant-pathology
#8
Aude Chabirand, Marianne Loiseau, Isabelle Renaudin, Françoise Poliakoff
A working group established in the framework of the EUPHRESCO European collaborative project aimed to compare and validate diagnostic protocols for the detection of "Flavescence dorée" (FD) phytoplasma in grapevines. Seven molecular protocols were compared in an interlaboratory test performance study where each laboratory had to analyze the same panel of samples consisting of DNA extracts prepared by the organizing laboratory. The tested molecular methods consisted of universal and group-specific real-time and end-point nested PCR tests...
2017: PloS One
https://www.readbyqxmd.com/read/28369334/nebcon-protein-contact-map-prediction-using-neural-network-training-coupled-with-na%C3%A3-ve-bayes-classifiers
#9
Baoji He, S M Mortuza, Yanting Wang, Hong-Bin Shen, Yang Zhang
Motivation: Recent CASP experiments have witnessed exciting progress on folding large-size non-humongous proteins with the assistance of co-evolution based contact predictions. The success is however anecdotal due to the requirement of the contact prediction methods for the high volume of sequence homologs that are not available to most of the non-humongous protein targets. Development of efficient methods that can generate balanced and reliable contact maps for different type of protein targets is essential to enhance the success rate of the ab initio protein structure prediction...
March 28, 2017: Bioinformatics
https://www.readbyqxmd.com/read/28367080/prevalence-and-risk-factors-of-comorbidities-among-hypertensive-patients-in-china
#10
Jiaojiao Wang, Jian James Ma, Jiaqi Liu, Daniel Dajun Zeng, Cynthia Song, Zhidong Cao
Hypertension is a severe threat to human being's health due to its association with many comorbidities. Many research works have explored hypertension's prevalence and treatment. However, few considered impact of patient's socioeconomic status and geographical disparities. We intended to fulfill that research gap by analyzing the association of the prevalence of hypertension and three important comorbidities with various socioeconomic and geographical factors. We also investigated the prevalence of those comorbidities if the patient has been diagnosed with hypertension...
2017: International Journal of Medical Sciences
https://www.readbyqxmd.com/read/28298358/identification-of-%C3%AE-catenin-interacting-proteins-in-nuclear-fractions-of-native-rat-collecting-duct-cells
#11
Jacqueline R Hwang, Chung-Lin Chou, Barbara Medvar, Mark A Knepper, Hyun Jun Jung
The gene encoding the aquaporin-2 water channel is regulated transcriptionally in response to vasopressin. In the renal collecting duct, vasopressin stimulates the nuclear translocation and phosphorylation (at Ser552) of β-catenin, a multifunctional protein that acts as a transcriptional co-regulator in the nucleus. The purpose of this study was to identify β-catenin interacting proteins that may be involved in transcriptional regulation in rat inner medullary collecting duct (IMCD) cells using both experimental and computational approaches...
March 15, 2017: American Journal of Physiology. Renal Physiology
https://www.readbyqxmd.com/read/28295782/multicenter-screening-for-preeclampsia-by-maternal-factors-and-biomarkers-at-11-13-weeks-gestation-comparison-to-nice-guidelines-and-acog-recommendations
#12
Neil O' Gorman, David Wright, Liona C Poon, Daniel L Rolnik, Argyro Syngelaki, Mercedes de Alvarado, Ilma F Carbone, Vivien Dutemeyer, Madgalena Fiolna, Alex Frick, Natalia Karagiotis, Sofia Mastrodima, Catalina de Paco Matallana, George Papaioannou, Andrea Pazos, Walter Plasencia, Kypros H Nicolaides
OBJECTIVE: To compare the performance of screening for preeclampsia (PE) based on risk factors from the medical history, as recommended by NICE and ACOG, with the method proposed by the Fetal Medicine Foundation (FMF), which uses Bayes theorem to combine the a priori risk from maternal factors, derived by a multivariable logistic model, with the results of various combinations of biophysical and biochemical measurements. METHODS: This was a prospective multicenter study of screening for PE in 8,775 singleton pregnancies at 11-13 weeks' gestation...
March 10, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28247184/bayesian-methods-for-calibrating-health-policy-models-a-tutorial
#13
Nicolas A Menzies, Djøra I Soeteman, Ankur Pandya, Jane J Kim
Mathematical simulation models are commonly used to inform health policy decisions. These health policy models represent the social and biological mechanisms that determine health and economic outcomes, combine multiple sources of evidence about how policy alternatives will impact those outcomes, and synthesize outcomes into summary measures salient for the policy decision. Calibrating these health policy models to fit empirical data can provide face validity and improve the quality of model predictions. Bayesian methods provide powerful tools for model calibration...
February 28, 2017: PharmacoEconomics
https://www.readbyqxmd.com/read/28225651/robotic-surgery-a-solution-in-search-of-a-problem-a-bayesian-analysis-of-343-robotic-procedures-performed-by-a-single-surgical-team
#14
Simona Manciu, Mihnea Dragomir, Fabiana Curea, Catalin Vasilescu
BACKGROUND: Despite the obvious technical advantages, the value of robotic surgery is highly debated and its cost-effectiveness has been questioned. The aim of this article is to provide an evaluation of the outcomes of robotic surgery in comparison to conventional laparoscopy. METHODS: A decision analysis based on the Bayes' theorem and the decision tree was used. The robotic approach was compared with the laparoscopic approach for each of the pathologies discussed in this study...
April 2017: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/28178332/a-hierarchical-estimator-development-for-estimation-of-tire-road-friction-coefficient
#15
Xudong Zhang, Dietmar Göhlich
The effect of vehicle active safety systems is subject to the friction force arising from the contact of tires and the road surface. Therefore, an adequate knowledge of the tire-road friction coefficient is of great importance to achieve a good performance of these control systems. This paper presents a tire-road friction coefficient estimation method for an advanced vehicle configuration, four-motorized-wheel electric vehicles, in which the longitudinal tire force is easily obtained. A hierarchical structure is adopted for the proposed estimation design...
2017: PloS One
https://www.readbyqxmd.com/read/28078815/repeat-measurements-of-uterine-artery-pulsatility-index-mean-arterial-pressure-and-serum-placental-growth-factor-at-12-22-and-32-weeks-in-the-prediction-of-preeclampsia
#16
Silvia Andrietti, Stefania Carlucci, Alan Wright, David Wright, Kypros H Nicolaides
OBJECTIVE: To investigate the potential value of repeat measurements of uterine artery pulsatility index (UTPI), mean arterial pressure (MAP) and serum placental growth factor (PLGF) at 12, 22 and 32 weeks' gestation in the prediction of preeclampsia (PE) after 32 weeks. METHODS: The data were derived from prospective screening for adverse obstetric outcomes in women attending for their routine hospital visit at 11-13, 19-24 and / or 30-34 weeks' gestation in two maternity hospitals in England...
January 12, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28039431/data-integration-in-physiology-using-bayes-rule-and-minimum-bayes-factors-deubiquitylating-enzymes-in-the-renal-collecting-duct
#17
Zhe Xue, Jia-Xu Chen, Yue Zhao, Barbara Medvar, Mark A Knepper
A major challenge in physiology is to exploit the many large-scale data sets available from "-omic" studies to seek answers to key physiological questions. In previous studies, Bayes' theorem has been used for this purpose. This approach requires a means to map continuously distributed experimental data to probabilities (likelihood values) to derive posterior probabilities from the combination of prior probabilities and new data. Here, we introduce the use of minimum Bayes' factors for this purpose and illustrate the approach by addressing a physiological question, "Which deubiquitylating enzymes (DUBs) encoded by mammalian genomes are most likely to regulate plasma membrane transport processes in renal cortical collecting duct principal cells?" To do this, we have created a comprehensive online database of 110 DUBs present in the mammalian genome (https://hpcwebapps...
March 1, 2017: Physiological Genomics
https://www.readbyqxmd.com/read/28002465/inference-of-functionally-relevant-n-acetyltransferase-residues-based-on-statistical-correlations
#18
Andrew F Neuwald, Stephen F Altschul
Over evolutionary time, members of a superfamily of homologous proteins sharing a common structural core diverge into subgroups filling various functional niches. At the sequence level, such divergence appears as correlations that arise from residue patterns distinct to each subgroup. Such a superfamily may be viewed as a population of sequences corresponding to a complex, high-dimensional probability distribution. Here we model this distribution as hierarchical interrelated hidden Markov models (hiHMMs), which describe these sequence correlations implicitly...
December 2016: PLoS Computational Biology
https://www.readbyqxmd.com/read/27939016/diagnosing-pulmonary-embolisms-the-clinician-s-point-of-view
#19
A Carrillo Alcaraz, A López Martínez, F J Sotos Solano
Pulmonary thromboembolism is common and potentially severe. To ensure the correct approach to the diagnostic workup of pulmonary thromboembolism, it is essential to know the basic concepts governing the use of the different tests available. The diagnostic approach to pulmonary thromboembolism is an example of the application of the conditional probabilities of Bayes' theorem in daily practice. To interpret the available diagnostic tests correctly, it is necessary to analyze different concepts that are fundamental for decision making...
March 2017: Radiología
https://www.readbyqxmd.com/read/27821399/examination-of-medication-clinical-decision-support-using-bayes-theorem
#20
Thomas H Payne, Bimal R Desai
No abstract text is available yet for this article.
November 15, 2016: American Journal of Health-system Pharmacy: AJHP
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