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https://www.readbyqxmd.com/read/29060258/tunable-nanostructured-conducting-polymers-for-neural-interface-applications
#1
Martin Antensteiner, Mohammad Reza Abidian
Advancement in the development of traditional metallic-based implantable electrodes for neural interfacing has reached a plateau in recent years in terms of their ability to provide safe, long-term, and high resolution stimulation and/or recording. The reduction of electrode size enables higher selectivity through increased electrodes per implant device; however, it also results in lower sensitivity at electrode-tissue interfaces. This limitation can be addressed through the utilization of conducting polymer (CP) coatings, which increase the effective surface area...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29040345/eight-year-safety-data-for-round-and-anatomical-silicone-gel-breast-implants
#2
Franck Duteille, Pierre Perrot, Marie-Hélène Bacheley, Sharon Stewart
Background: The safety and efficacy of all medical devices, including breast implants, is important and consistent performance is best shown by undertaking long-term clinical and vigilance studies. Local complications such as capsular contracture and rupture are risks often associated with breast implant surgery. Objectives: The authors investigate and evaluate the safety and performance of Eurosilicone's (Eurosilicone S.A.S, Apt Cedex, France) Cristalline Paragel breast implants at 8 years postimplantation...
June 24, 2017: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/28940603/long-term-stable-vertical-bone-regeneration-after-sinus-floor-elevation-and-simultaneous-implant-placement-with-and-without-grafting
#3
Fernando Verdugo, Agurne Uribarri, Theresia Laksmana, Antonio D'addona
BACKGROUND: Less invasive surgical approaches to regenerate bone intra-sinus and allow long-term functional implant stability are needed. PURPOSE: To evaluate long-term vertical bone regeneration after sinus floor elevation and simultaneous implant placement with and without bone grafting. METHODS: Vertical bone gains (VBG) post-sinus elevation, with and without grafting, were evaluated in thirty individuals presenting an average residual bone height (RBH) of 4...
September 21, 2017: Clinical Implant Dentistry and related Research
https://www.readbyqxmd.com/read/28935450/needle-migration-and-dosimetric-impact-in-high-dose-rate-brachytherapy-for-prostate-cancer-evaluated-by-repeated-mri
#4
Simon Buus, Maria Lizondo, Steffen Hokland, Susanne Rylander, Erik M Pedersen, Kari Tanderup, Lise Bentzen
PURPOSE: To quantify needle migration and dosimetric impact in high-dose-rate brachytherapy for prostate cancer and propose a threshold for needle migration. METHODS AND MATERIALS: Twenty-four high-risk prostate cancer patients treated with an HDR boost of 2 × 8.5 Gy were included. Patients received an MRI for planning (MRI1), before (MRI2), and after treatment (MRI3). Time from needle insertion to MRI3 was ∼3 hours. Needle migration was evaluated from coregistered images: MRI1-MRI2 and MRI1-MRI3...
September 18, 2017: Brachytherapy
https://www.readbyqxmd.com/read/28650944/intramedullary-implant-choice-and-cost-in-the-treatment-of-pediatric-diaphyseal-forearm-fractures
#5
Austin Heare, Dawn Goral, Matthew Belton, Corey Beebe, Anastasiya Trizno, Jason Stoneback
OBJECTIVES: To compare outcomes and costs between titanium elastic nails (TENs), stainless steel elastic nails (SENs), and Kirschner wires (K-wires) in the treatment of pediatric diaphyseal forearm fractures with intramedullary fixation. DESIGN: Retrospective cohort study. SETTING: Level 1 Pediatric Trauma Center. PATIENTS/PARTICIPANTS: A total of 100 patients (65 male and 35 female) younger than 18 years with diaphyseal forearm fractures treated with intramedullary fixation were included in the study...
October 2017: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/28619484/the-new-opt-out-dutch-national-breast-implant-registry-lessons-learnt-from-the-road-to-implementation
#6
Hinne A Rakhorst, Marc A M Mureau, Rodney D Cooter, John McNeil, Miranda van Hooff, René van der Hulst, Juliette Hommes, Marije Hoornweg, Laura Moojen-Zaal, Patricia Liem, Irene M J Mathijssen
An estimated 1-3% of all women in the Netherlands carry breast implants. Since the introduction five decades ago, problems with a variety of breast implants have emerged with direct consequences for the patients' health. Plastic surgeons worldwide reacted through campaigning for auditing on long-term implant quality, surgeon performance, and institutional outcomes in implant registries. Especially, the PIP implant scandal of 2010 demonstrated the paucity of epidemiological data and uncovered a weakness in our ability to even 'track and trace' patients...
October 2017: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/28609492/correlation-of-three-dimensional-radiologic-data-with-subsequent-treatment-approach-in-patients-with-peri-implantitis-a-retrospective-analysis
#7
Philip Bender, Giovanni E Salvi, Daniel Buser, Anton Sculean, Michael M Bornstein
The purpose of this retrospective radiographic study was to evaluate and correlate the dimensions and morphology of peri-implant bone defects as determined via cone beam computed tomography (CBCT) scans with regard to the selected treatment approach. Vertical and horizontal peri-implant bone defects (mesial, distal, mesio-oral, mesiobuccal, disto-oral, distobuccal, oral, and buccal) in peri-implantitis cases were measured. Three-dimensional data and defect morphology were correlated to the treatment approach chosen (explantation versus implant retention)...
July 2017: International Journal of Periodontics & Restorative Dentistry
https://www.readbyqxmd.com/read/28442372/long-term-release-and-stability-of-pharmaceutical-proteins-delivered-from-solid-lipid-implants
#8
Moritz Vollrath, Julia Engert, Gerhard Winter
Solid lipid implants (SLIs) prepared by twin-screw (tsc) extrusion represent a promising technology platform for the sustained release of pharmaceutical proteins. In this work, we report on two aspects, long-term release and stability of released protein. First, SLIs were produced by tsc-extrusion containing the low melting triglyceride H12 and the high melting triglyceride Dynasan D118. Two different proteins available in a freeze-dried matrix containing hydroxypropyl-β-cyclodextrine (HP-β-CD) were incorporated into the lipid matrix: a monoclonal antibody (mAb) from the IgG1 class and the fab-fragment Ranibizumab (Lucentis(®))...
April 22, 2017: European Journal of Pharmaceutics and Biopharmaceutics
https://www.readbyqxmd.com/read/28406048/placement-of-central-venous-port-catheters-and-peripherally-inserted-central-catheters-in-the-routine-clinical-setting-of-a-radiology-department-analysis-of-costs-and-intervention-duration-learning-curve
#9
Roman Rotzinger, Bernhard Gebauer, Dirk Schnapauff, Florian Streitparth, Gero Wieners, Christian Grieser, Patrick Freyhardt, Bernd Hamm, Martin H Maurer
Background Placement of central venous port catheters (CVPS) and peripherally inserted central catheters (PICC) is an integral component of state-of-the-art patient care. In the era of increasing cost awareness, it is desirable to have more information to comprehensively assess both procedures. Purpose To perform a retrospective analysis of interventional radiologic implantation of CVPS and PICC lines in a large patient population including a cost analysis of both methods as well as an investigation the learning curve in terms of the interventions' durations...
January 1, 2017: Acta Radiologica
https://www.readbyqxmd.com/read/28398014/brain-responsive-neurostimulation-in-patients-with-medically-intractable-mesial-temporal-lobe-epilepsy
#10
RANDOMIZED CONTROLLED TRIAL
Eric B Geller, Tara L Skarpaas, Robert E Gross, Robert R Goodman, Gregory L Barkley, Carl W Bazil, Michael J Berg, Gregory K Bergey, Sydney S Cash, Andrew J Cole, Robert B Duckrow, Jonathan C Edwards, Stephan Eisenschenk, James Fessler, Nathan B Fountain, Alicia M Goldman, Ryder P Gwinn, Christianne Heck, Aamar Herekar, Lawrence J Hirsch, Barbara C Jobst, David King-Stephens, Douglas R Labar, James W Leiphart, W Richard Marsh, Kimford J Meador, Eli M Mizrahi, Anthony M Murro, Dileep R Nair, Katherine H Noe, Yong D Park, Paul A Rutecki, Vicenta Salanova, Raj D Sheth, Donald C Shields, Christopher Skidmore, Michael C Smith, David C Spencer, Shraddha Srinivasan, William Tatum, Paul C Van Ness, David G Vossler, Robert E Wharen, Gregory A Worrell, Daniel Yoshor, Richard S Zimmerman, Kathy Cicora, Felice T Sun, Martha J Morrell
OBJECTIVE: Evaluate the seizure-reduction response and safety of mesial temporal lobe (MTL) brain-responsive stimulation in adults with medically intractable partial-onset seizures of mesial temporal lobe origin. METHODS: Subjects with mesial temporal lobe epilepsy (MTLE) were identified from prospective clinical trials of a brain-responsive neurostimulator (RNS System, NeuroPace). The seizure reduction over years 2-6 postimplantation was calculated by assessing the seizure frequency compared to a preimplantation baseline...
June 2017: Epilepsia
https://www.readbyqxmd.com/read/28377897/relationship-of-number-of-embryos-transferred-with-perinatal-outcome-of-singleton-pregnancy
#11
Shilpa Bhandari, Ishita Ganguly, Pallavi Agarwal, Niharika Munaganuru, Nitika Gupta, Aparna Singh
BACKGROUND: Singleton pregnancy with a live birth beyond 37 weeks of gestation is the ultimate goal of any assisted reproductive technology. However, singletons conceived after ART are found to have a poor perinatal outcome in comparison to naturally conceived singletons. It was hypothesized that the outcome of singleton conceived after transfer of two or more embryos may be dependent on the sharing of uterine space with other embryos. METHODS: Patients who had single gestational sac visualized at 6 weeks after transfer of 4, 3 or 2 embryos were considered for the study...
January 2017: Journal of Reproduction & Infertility
https://www.readbyqxmd.com/read/28343651/reconstruction-of-large-cranial-defects-with-poly-methyl-methacrylate-pmma-using-a-rapid-prototyping-model-and-a-new-technique-for-intraoperative-implant-modeling
#12
Claudia Unterhofer, Christoph Wipplinger, Michael Verius, Wolfgang Recheis, Claudius Thomé, Martin Ortler
BACKGROUND: Reconstruction of large cranial defects after craniectomy can be accomplished by free-hand poly-methyl-methacrylate (PMMA) or industrially manufactured implants. The free-hand technique often does not achieve satisfactory cosmetic results but is inexpensive. In an attempt to combine the accuracy of specifically manufactured implants with low cost of PMMA. METHODS: Forty-six consecutive patients with large skull defects after trauma or infection were retrospectively analyzed...
May 2017: Neurologia i Neurochirurgia Polska
https://www.readbyqxmd.com/read/28185409/a-retrospective-study-on-1592-consecutively-performed-operations-in-one-private-referral-clinic-part-i-early-inflammation-and-early-implant-failures
#13
Hadi Antoun, Michel Karouni, Jérémy Abitbol, Ons Zouiten, Torsten Jemt
BACKGROUND: Few large-scale follow-up studies are reported on routine implant treatment. PURPOSE: To report retrospective data on early inflammatory and early implant failures in a large number of routine patients at one private referral clinic. MATERIALS AND METHODS: A total of 1017 patients were consecutively provided with 3082 implants with an anodized surface (Nobel Biocare AB) at 1592 implant operations between 2000 and 2011. All patients reported with mucosa inflammation and bone loss and/or implant failures to the first annual examination were identified...
June 2017: Clinical Implant Dentistry and related Research
https://www.readbyqxmd.com/read/28093860/monolithic-implant-supported-lithium-disilicate-ls2-crowns-in-a-complete-digital-workflow-a-prospective-clinical-trial-with-a-2-year-follow-up
#14
Tim Joda, Marco Ferrari, Urs Brägger
BACKGROUND: The technical development of digital processing allows the production of anatomically full-contoured implant-supported restorations. PURPOSE: The aim of this prospective clinical trial was to analyze the treatment concept of monolithic lithium disilicate (LS2) single-unit restorations in a complete digital workflow. MATERIAL AND METHODS: Forty-four patients were restored with 50 screw-retained monolithic implant LS2 crowns bonded to pre-fabricated titanium abutments on soft tissue level implants (Institut Straumann AG, Basel, Switzerland) in premolar and molar sites...
June 2017: Clinical Implant Dentistry and related Research
https://www.readbyqxmd.com/read/28063250/comparative-3d-micro-ct-and-2d-histomorphometry-analysis-of-dental-implant-osseointegration-in-the-maxilla-of-minipigs
#15
Oliver Bissinger, Florian Andreas Probst, Klaus-Dietrich Wolff, Anke Jeschke, Jochen Weitz, Herbert Deppe, Andreas Kolk
AIM: The bone implant contact (BIC) has traditionally been evaluated with histological methods. Thereupon, strong correlations of two-dimensional (2D) BIC have been detected between μCT and destructive histology. However, due to the high intra-sample variability in BIC values, one histological slice is not sufficient to represent 3D BIC. Therefore, our aim has been to correlate the averaged values of 3-4 histological sections to 3D μCT. MATERIAL AND METHODS: Fifty-four implants inserted into the maxilla of 14 minipigs were evaluated...
January 7, 2017: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28032908/adjunctive-efficacy-of-probiotics-in-the-treatment-of-experimental-peri-implant-mucositis-with-mechanical-and-photodynamic-therapy-a-randomized-cross-over-clinical-trial
#16
Claudio Mongardini, Andrea Pilloni, Roberto Farina, Gianluca Di Tanna, Blerina Zeza
AIM: To evaluate the adjunctive clinical efficacy of probiotics in the treatment of peri-implant mucositis (p-iM) with professionally administered plaque removal (PAPR) and photodynamic therapy (PDT). MATERIALS AND METHODS: Following p-iM induction, patients underwent PAPR + PDT and were randomly assigned to receive the professional and home-based administration of probiotics (Lactobacillus plantarum and Lactobacillus brevis) (test treatment) or placebo preparation (control treatment) according to a cross-over design...
December 29, 2016: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/27884358/application-of-3-dimensional-computed-tomographic-image-guidance-to-watchman-implantation-and-impact-on%C3%A2-early-operator-learning-curve-single-center-experience
#17
COMPARATIVE STUDY
Dee Dee Wang, Marvin Eng, Daniel Kupsky, Eric Myers, Michael Forbes, Mehnaz Rahman, Mohammad Zaidan, Sachin Parikh, Janet Wyman, Milan Pantelic, Thomas Song, Jeff Nadig, Patrick Karabon, Adam Greenbaum, William O'Neill
OBJECTIVES: The aim of this study was to examine the impact of 3-dimensional (3D) computed tomographic (CT) guided procedural planning for left atrial appendage (LAA) occlusion on the early operator WATCHMAN learning curve. BACKGROUND: Traditional WATCHMAN implantation is dependent on 2-dimensional transesophageal echocardiographic (TEE) sizing and intraprocedural guidance. METHODS: LAA occlusion with the WATCHMAN device was performed in 53 patients...
November 28, 2016: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/27639485/how-does-implant-distribution-affect-3d-correction-and-bone-screw-forces-in-thoracic-adolescent-idiopathic-scoliosis-spinal-instrumentation
#18
Franck Le Navéaux, A Noelle Larson, Hubert Labelle, Xiaoyu Wang, Carl-Éric Aubin
BACKGROUND: Optimal implant densities and configurations for thoracic spine instrumentation to treat adolescent idiopathic scoliosis remain unknown. The objective was to computationally assess the biomechanical effects of implant distribution on 3D curve correction and bone-implant forces. METHODS: 3D patient-specific biomechanical spine models based on a multibody dynamic approach were created for 9 Lenke 1 patients who underwent posterior instrumentation (main thoracic Cobb: 43°-70°)...
November 2016: Clinical Biomechanics
https://www.readbyqxmd.com/read/27553255/a-prospective-clinical-cohort-study-analyzing-single-unit-implant-crowns-after-three-years-of-loading-introduction-of-a-novel-functional-implant-prosthodontic-score-fips
#19
Tim Joda, Marco Ferrari, Urs Bragger
OBJECTIVES: The aim of this prospective clinical cohort study was to validate implant crowns with a novel Functional Implant Prosthodontic Score (FIPS). MATERIAL AND METHODS: Twenty patients were restored with cement-retained crowns on soft tissue level implants (Institut Straumann AG, Basel, Switzerland) in posterior sites and annually followed-up for 3 years. FIPS was applied for the objective outcome assessment including clinical and radiographic examinations...
August 23, 2016: Clinical Oral Implants Research
https://www.readbyqxmd.com/read/27504130/clinical-applications-of-custom-made-vaginal-cylinders-constructed-using-three-dimensional-printing-technology
#20
Rajni Sethi, Adam Cunha, Katherine Mellis, Timmy Siauw, Chris Diederich, Jean Pouliot, I-Chow Hsu
PURPOSE: Three-dimensional (3D) printing technology allows physicians to rapidly create customized devices for patients. We report our initial clinical experience using this technology to create custom applicators for vaginal brachytherapy. MATERIAL AND METHODS: Three brachytherapy patients with unique clinical needs were identified as likely to benefit from a customized vaginal applicator. Patient 1 underwent intracavitary vaginal cuff brachytherapy after hysterectomy and chemotherapy for stage IA papillary serous endometrial cancer using a custom printed 2...
June 2016: Journal of Contemporary Brachytherapy
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