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https://www.readbyqxmd.com/read/29333088/bone-regeneration-using-silk-hydroxyapatite-hybrid-composite-in-a-rat-alveolar-defect-model
#1
Kyung S Koh, Jong Woo Choi, Eun Jeong Park, Tae Suk Oh
Background: To overcome the limited source of autogenous bone in bone grafting, many efforts have been made to find bone substitutes. The use of hybrid composites of silk and hydroxyapatite to simulate natural bone tissue can overcome the softness and brittleness of the individual components. Methods: Critical-sized, 7 x 4 x 1.5 mm alveolar defects were created surgically in 36 Sprague-Dawley rats. Three treatment groups were tested: an empty defect group (group I), a silk fibrin scaffold group (group II), and a hydroxyapatite-conjugated silk fibrin scaffold group (group III)...
2018: International Journal of Medical Sciences
https://www.readbyqxmd.com/read/29332945/the-human-skin-microbiome
#2
REVIEW
Allyson L Byrd, Yasmine Belkaid, Julia A Segre
Functioning as the exterior interface of the human body with the environment, skin acts as a physical barrier to prevent the invasion of foreign pathogens while providing a home to the commensal microbiota. The harsh physical landscape of skin, particularly the desiccated, nutrient-poor, acidic environment, also contributes to the adversity that pathogens face when colonizing human skin. Despite this, the skin is colonized by a diverse microbiota. In this Review, we describe amplicon and shotgun metagenomic DNA sequencing studies that have been used to assess the taxonomic diversity of microorganisms that are associated with skin from the kingdom to the strain level...
January 15, 2018: Nature Reviews. Microbiology
https://www.readbyqxmd.com/read/29331885/autonomously-hyperfunctioning-cystic-nodule-harbouring-thyroid-carcinoma-case-report-and-literature-review
#3
Maria João Lima, Virgínia Soares, Pedro Koch, Artur Silva, António Taveira-Gomes
INTRODUCTION: Hyperthyroidism is rarely associated with malignancy, but it cannot rule out thyroid cancer. Although there is published data describing this coexistence, thyroid carcinomas inside autonomously functioning nodules are uncommon. PRESENTATION OF CASE: A 49-year-old woman presented with a cervical mass, unexplained weight loss and anxiousness, sweating and insomnia. On physical examination, she had a palpable left thyroid nodule. Thyroid function tests showed suppressed TSH (<0,1 uUI/mL), thyroxine 1,44 ng/dL (normal range 0,70-1,48) and triiodothyronine 4,33 pg/mL (normal range 1,71-3,71)...
January 8, 2018: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29331260/multifaceted-behavior-of-meckel-s-diverticulum-in-children
#4
Qingjiang Chen, Zhigang Gao, Lifeng Zhang, Yuebin Zhang, Tao Pan, Duote Cai, Qixing Xiong, Qiang Shu, Yunzhong Qian
PURPOSE/BACKGROUND: Meckel's diverticulum (MD) is one of the most common congenital malformations of gastrointestinal tract in children. However, the nonspecific clinical manifestations of MD often cause a diagnostic as well as therapeutic challenge to pediatric surgeon. This study aimed to review our experience in managing this disease while evaluating the management strategies. METHODS: We retrospectively analyzed the clinical data of all patients diagnosed with MD admitted to our center between January 2010 and December 2015...
December 5, 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/29330824/colonic-fistula-caused-by-remaining-inflow-cannula-14%C3%A2-years-after-left-ventricular-assist-device-explantation
#5
Shunsuke Saito, Koichi Toda, Shigeru Miyagawa, Yasushi Yoshikawa, Hiroki Hata, Keitaro Domae, Ryohei Matsuura, Yoshiki Sawa
Intestinal complication associated with left ventricular assist device (LVAD) implantation is not rare, and sometimes results in serious condition of patients, if occurred. We report a rare case in which remaining foreign body after LVAD explantation resulted in colonic fistula 14 years after LVAD explantation.
January 12, 2018: Journal of Artificial Organs: the Official Journal of the Japanese Society for Artificial Organs
https://www.readbyqxmd.com/read/29330580/-lichen-ruber-planus-better-understanding-better-treatment
#6
REVIEW
L Schilling, T Vogt
Lichen ruber, also called lichen ruber planus or lichen planus (LP), is a noncontagious inflammatory skin disease. LP is the main representative and namesake of the group of lichenoid diseases, which are characterized by small papules often accompanied by severe itching. With 65% of cases, LP is primarily a disease of the mucous membranes. In 20% of the cases, the disease is found on the skin and mucous membranes; skin involvement alone is seen in only about 10% of cases. Cutaneous LP has a very favorable 1‑year prognosis of almost 80% healing as opposed to the mucosa and the adnexal organs...
January 12, 2018: Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete
https://www.readbyqxmd.com/read/29328785/immune-responses-in-the-liver
#7
Paul Kubes, Craig Jenne
The liver is a key, frontline immune tissue. Ideally positioned to detect pathogens entering the body via the gut, the liver appears designed to detect, capture, and clear bacteria, viruses, and macromolecules. Containing the largest collection of phagocytic cells in the body, this organ is an important barrier between us and the outside world. Importantly, as portal blood also transports a large number of foreign but harmless molecules (e.g., food antigens), the liver's default immune status is anti-inflammatory or immunotolerant; however, under appropriate conditions, the liver is able to mount a rapid and robust immune response...
January 12, 2018: Annual Review of Immunology
https://www.readbyqxmd.com/read/29328540/case-of-late-onset-relapsing-surgical-site-infection-related-to-a-venous-coupler-placed-during-free-flap-reconstruction-for-major-head-and-neck-cancer
#8
Yin Ren, Daniel G Deschler, Dipti Sajed, Marlene L Durand
BACKGROUND: Venous coupling devices are widely used during reconstructive surgery involving microvascular anastomosis but have not served as foreign bodies in head and neck surgical site infections. METHODS: We conducted a case report. RESULTS: A patient underwent resection and free flap reconstruction for recurrent tongue squamous cell carcinoma. She developed a neck abscess due to Streptococcus intermedius 7 weeks postoperatively, days after starting chemoradiotherapy...
January 12, 2018: Head & Neck
https://www.readbyqxmd.com/read/29327964/endoscopic-removal-of-gastrointestinal-foreign-bodies-in-two-african-grey-parrots-psittacus-erithacus-and-a-hyacinth-macaw-anodorhynchus-hyacinthinus
#9
Robert J Cotton, Stephen J Divers
Two African grey parrots ( Psittacus erithacus) and one hyacinth macaw ( Anodorhynchus hyacinthinus) were examined because of varying clinical signs ranging from general lethargy to seizure-like episodes and regurgitation. Radiography and fluoroscopy in the 3 birds demonstrated variable degrees of gastric abnormalities, suggesting the presence of foreign material or stricture-like defects. Upper gastrointestinal rigid endoscopy by ingluviotomy revealed foreign bodies that were removed endoscopically. Minor postoperative complications were pulmonary congestion or mild aspiration and cardiac arrhythmia, both of which resolved, and no serious deleterious effects were associated with endoscopy in the short or long term...
December 2017: Journal of Avian Medicine and Surgery
https://www.readbyqxmd.com/read/29327961/tracheal-resection-in-a-secretary-bird-sagittarius-serpentarius-with-granulomatous-foreign-body-induced-tracheitis
#10
Carsten Ludwig, Imke Lueders, Volker Schmidt, Hermann Kempf
A 24-year-old female secretary bird ( Sagittarius serpentarius) was presented with acute, mild dyspnea occurring only during feeding times. Despite initial conservative therapy consisting of antibiotics and antifungal, antiparasitic, and anti-inflammatory drugs, the dyspnea worsened progressively, resulting in severe respiratory distress. Radiographs of the trachea suggested stenosis in the caudal one-third of the trachea. Tracheal endoscopy revealed an obstruction of approximately 90% of the tracheal lumen, in addition to mild suspected aspergillosis of the air sacs...
December 2017: Journal of Avian Medicine and Surgery
https://www.readbyqxmd.com/read/29327650/transesophageal-echocardiography-use-in-diagnosis-and-management-of-embolized-intravascular-foreign-bodies
#11
James Taylor Herbert, Miklos David Kertai
The increasing use of endovascular interventions coupled with the large number of published case series detailing complications attest to the likelihood that anesthesiologists will encounter a case of intravascular foreign body embolization during their careers. Transesophageal echocardiography is essential to the diagnosis and management of traumatic and intravascular foreign bodies embolized to the heart because it can identify not only the foreign body but also hemodynamically significant lesions to radiolucent anatomic structures prior to and during surgical exploration...
October 1, 2017: Seminars in Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/29327493/a-prospective-cohort-study-of-122-adult-patients-presenting-to-an-otolaryngologist-s-office-with-globus-pharyngeus
#12
Eva Rye Rasmussen, Didde Traerup Schnack, Andreas Tomaas Ravn
OBJECTIVES: To investigate the epidemiology of globus pharyngeus in adult patients presenting to the otolaryngologist's office. Also the predictors of persisting symptoms, prevalence of anxiety and the effect of clinical assessment were analyzed. DESIGN: This was a prospective cohort study. Follow-up was done using a postal questionnaire. SETTING: One otolaryngologists' office comprising three medical doctors. PARTICIPANTS: 122 consecutive globus patients presenting to one otolaryngology office in a one-year period...
January 11, 2018: Clinical Otolaryngology
https://www.readbyqxmd.com/read/29325526/aortoesophageal-fistula-and-arch-pseudoaneurysm-after-removing-of-a-swallowed-chicken-bone-a-case-report-of-one-stage-hybrid-treatment
#13
Jia-Yu Shen, Hong-Wei Zhang, Kang-Jun Fan, Hu Liao, Er-Yong Zhang, Jia Hu
BACKGROUND: Aortoesophageal fistula (AEF) and arch pseudoaneurysm are rare complications induced by a foreign body, and considerable controversy remains regarding the appropriate management strategies. We herein report a successful one-stage hybrid treatment in a patient with AEF and arch pseudoaneurysm. CASE PRESENTATION: The patient, a 40-year-old man, presented to the emergency room because of intense retrosternal discomfort for 3 days and hematemesis for 3 h...
January 11, 2018: BMC Surgery
https://www.readbyqxmd.com/read/29324792/critical-evaluation-of-colon-submucosal-microdialysis-in-awake-mobile-rats
#14
Norbert Cibicek, Jiri Ehrmann, Jitka Proskova, Rostislav Vecera
Sensors able to record large bowel physiology and biochemistry in situ in awake rodents are lacking. Microdialysis is a mini-invasive technique that may be utilized to continuously deliver or recover low-molecular substances from various tissues. In this experiment we evaluated the feasibility of in vivo microdialysis to monitor extracellular fluid chemistry in the descending colon submucosa of conscious, freely moving rodents. Following surgical implantation of a microdialysis probe, male Wistar rats were housed in metabolic cages where they were analgized and clinically followed for four days with free access to standard diet and water...
2018: PloS One
https://www.readbyqxmd.com/read/29322834/a-tertiary-centre-experience-of-thoracic-ct-and-cardiac-mri-scanning-in-the-presence-of-a-reveal-linq-insertable-cardiac-monitoring-system-a-case-series-review-of-artefact-patient-safety-and-data-preservation
#15
Benedict M Wiles, Caroline A Illingworth, Michael Lg Couzins, Paul R Roberts, Stephen P Harden
OBJECTIVE: At our tertiary cardiothoracic centre cardiac MRI and thoracic CT scans are performed in patients with implanted LINQ devices. The degree of foreign body artefact associated with the LINQ device, and its clinical importance, has not previously been assessed. A case series review was therefore performed with a simultaneous review of patient safety and data loss events, secondary to the MRI environment. METHODS: A local database search identified LINQ device patients who underwent thoracic CT or cardiac MRI scans between March 2014 and December 2016...
January 11, 2018: British Journal of Radiology
https://www.readbyqxmd.com/read/29322121/silicone-granuloma-associated-with-pectoral-muscle-involvement-after-ruptured-breast-implant-a-novel-case-report
#16
Türkan İkizceli, Gökçe Gülşen, İlker Akın
In this study, an unusual case of a patient who was previously operated on a ruptured breast implant following silicone granuloma associated with pectoral muscle involvement is reported. A 72-year-old woman had undergone breast augmentation surgery when she was 52-year-old and silicone implant rupture 10 years later. After 10 years of ruptured silicone implant, her mammography showed diffuse, multiple high-density nodules in the left breast. The pectoral muscle was significantly hypertrophic. The magnetic resonance imaging showed that the pectoral muscle was quite hypertrophic and had heterogeneous enhancement...
January 2018: European Journal of Breast Health
https://www.readbyqxmd.com/read/29321924/lung-mycobacterium-avium-developed-after-removing-an-acupuncture-needle-from-the-lung
#17
Mikihito Saito, Hajime Kasai, Kengo Shimazu, Takashi Urushibara, Tomohiko Iida, Toshihide Shinozaki
Acupuncture needles can cause non-tuberculosis mycobacteria (NTM) infection on the skin, but there are no reports that acupuncture needles inserted into the lung have caused lung NTM infection. A 63-year-old woman, who underwent removal of a broken acupuncture needle inserted into the lung nine years ago, was admitted with nodules in the right lung. The shadow was positioned where the needle had existed. Partial lung resection of the right lower lobe was performed, and the resected area showed caseous necrosis histopathologically...
January 2018: Respirology Case Reports
https://www.readbyqxmd.com/read/29321844/foreign-body-reaction-with-granuloma-following-achilles-tendon-reconstruction-with-the-lars-ligament
#18
Joshua Henry, Alistar J Konarski, Leena Joseph, Anand Pillai
Ligament reconstruction with the LARS ligament has been a popular choice owing to its low-complication rates compared with previously commercially available grafts. The non-active nature of the implant also meant that there were no foreign body reactions that had been described with other synthetic grafts. We describe the first reported case of a granulomatous foreign body reaction in a LARS ligament Achilles tendon graft and a technique to reconstruct the tendon following its excision.
January 2018: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/29321197/iatrogenic-foreign-body-in-an-adult-with-presbyacusis
#19
Hannah Louise Morley
No abstract text is available yet for this article.
January 9, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29320791/-what-to-do-when-a-child-is-choking
#20
Jost Kaufmann, Michael Laschat, Frank Wappler
Both ingestion and aspiration of foreign bodies are common events in children. If a child had something in his mouth and thereafter respiratory or swallowing complaints occur, both aspiration and ingestion are possible causes. Both events can be immediately life threatening or, if a direct threat is absent, cause significant long-term impairments for the children. Therefore, the identification of any possible threat is essential. This paper identifies the diagnostic and therapeutic options and needs that will ensure the best possible safety and the least possible consequential harm...
January 2018: Anästhesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie: AINS
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