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Relapsing Polychondritis

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https://www.readbyqxmd.com/read/28331873/rapid-corneal-thinning-and-perforated-ulcerative-keratitis-in-a-patient-with-relapsing-polychondritis
#1
Tracy Hiu Ting Lai, Nikki Far, Alvin Lerrmann Young, Vishal Jhanji
BACKGROUND: To report rapid corneal thinning and perforation in a case with relapsing polychondritis. CASE PRESENTATION: A 43 year-old male diagnosed with relapsing polychondritis suffered from bilateral scleritis, bilateral swelling of pinna, saddle nose and tracheal stenosis. The patient presented with right eye pain and redness for one month. Slit lamp examination of the right eye showed 80% peripheral corneal thinning between 3 and 7 o'clock. The best-corrected visual acuity (BCVA) was 1...
2017: Eye and Vision (London, England)
https://www.readbyqxmd.com/read/28266051/relapsing-polychondritis-associated-with-psoriasis-vulgaris-successfully-treated-with-adalimumab-a-case-report-with-published-work-review
#2
Haruka Matsuo, Akihiko Asahina, Takeshi Fukuda, Yoshinori Umezawa, Hidemi Nakagawa
Relapsing polychondritis (RP) is a rare autoimmune-mediated disease characterized by inflammation involving cartilaginous tissues. We report here a case of RP in a 38-year-old Japanese man with 13-year duration of psoriasis vulgaris treated with topical steroids and vitamin D3 . The patient presented with tender swelling and erythema of both auricles, and the antibody to type II collagen was detected. The biopsy specimen revealed a dense mixed cell infiltration over the auricular cartilage. We reviewed eight cases with the association of RP and psoriasis, and in all cases the clinical course of psoriasis did not correlate with that of RP...
March 7, 2017: Journal of Dermatology
https://www.readbyqxmd.com/read/28262498/relapsing-polychondritis-prevalence-of-cardiovascular-diseases-and-its-risk-factors-and-general-disease-features-according-to-gender
#3
Pablo Arturo Olivo Pallo, Maurício Levy-Neto, Rosa Maria Rodrigues Pereira, Samuel Katsuyuki Shinjo
The comorbidities in relapsing polychondritis (RP) have been scarcely described in the literature. Moreover, apart from a few RP epidemiological studies, no studies specifically addressing RP distribution according to gender are available. Therefore, the objetives of the present study were: (a) to analyse the prevalence of cardiovascular diseases and its risk factors in a series of patients with RP; (b) to determine the influence of gender on RP. A cross-sectional tertiary single center study evaluating 30 RP cases from 1990 to 2016 was carried out...
February 20, 2017: Revista Brasileira de Reumatologia
https://www.readbyqxmd.com/read/28259367/relapsing-polychondritis-with-airway-involvement-a-clinical-challenge
#4
Marta Sousa, João Silva, Bárbara Rodrigues
No abstract text is available yet for this article.
March 1, 2017: Archivos de Bronconeumología
https://www.readbyqxmd.com/read/28243168/relapsing-polychondritis-presented-with-encephalitis-followed-by-brain-atrophy
#5
Suk-Won Ahn, Moo-Seok Park, Hae-Bong Jeong, Oh-Sang Kwon, Byung-Nam Yoon, Hee Sung Kim, Sang Tae Choi
Relapsing polychondritis (RP) is a rare autoimmune disease that is characterized by inflammatory reaction of unknown etiology and destruction of cartilaginous structures. Characteristic symptoms of this disease include cartilage inflammation of the ear, nose, larynx, trachea, bronchi, joints, eyes, heart and skin. Concomitance with neurologic symptom is very rare in RP, and the detailed underlying mechanism of neurological involvement associated with RP is not fully understood. We herein described an unusual recurrent case of inflammatory brain lesions associated with RP, with attention to clinical manifestations, autoimmune disease involvement, and therapeutic effects...
February 2017: Experimental Neurobiology
https://www.readbyqxmd.com/read/28229816/sustained-response-to-tocilizumab-in-a-patient-with-relapsing-polychondritis-complicated-by-aortitis
#6
Meritxell Sallés, Sonia Mínguez, Sandra Ros, Roser Tuneu, Saul Mario Gelman
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February 22, 2017: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/28215949/relapsing-polychondritis-with-myelodysplastic-syndrome-a-case-report
#7
Amrit K Kamboj, Thomas G Cotter, Cyril Varghese
No abstract text is available yet for this article.
March 2017: American Journal of Medicine
https://www.readbyqxmd.com/read/28207003/relapsing-polychondritis-with-meningoencephalitis
#8
Monica Tsai, Mengjun Hu, Jamie Zussman, Scott Worswick
Relapsing polychondritis (RP) is a rare autoimmune disease of the cartilaginous structures of the body with many systemic manifestations including meningoencephalitis (ME). We present a case of a man with RP-associated ME that was responsive to steroid treatment. An updated literature review of 7 cases of RP-associated ME also is provided. Early diagnosis of this condition may be of benefit to this select population of patients, and further research regarding the prognosis, mechanisms, and treatment of RP may be necessary in the future...
January 2017: Cutis; Cutaneous Medicine for the Practitioner
https://www.readbyqxmd.com/read/28131697/response-assessment-in-relapsing-polychondritis-with-18-f-fdg-pet-ct
#9
T K Jain, A Sood, A Sharma, R K Basher, A Bhattacharya, B R Mittal
No abstract text is available yet for this article.
January 25, 2017: Revista Española de Medicina Nuclear e Imagen Molecular
https://www.readbyqxmd.com/read/28120637/successful-treatment-with-tocilizumab-for-refractory-scleritis-associated-with-relapsing-polychondritis
#10
H Shimizu, H Nishioka
No abstract text is available yet for this article.
January 25, 2017: Scandinavian Journal of Rheumatology
https://www.readbyqxmd.com/read/28093782/relapsing-polychondritis-as-an-unusual-cause-of-multiple-cranial-nerve-palsies-a-case-report
#11
Fatme Seval Ismail, Björn Enzi, Christian Boy, Annika Kowoll, Jens Eyding, Uwe Schlegel
No abstract text is available yet for this article.
January 17, 2017: Muscle & Nerve
https://www.readbyqxmd.com/read/28049117/rare-cause-of-bilateral-sudden-deafness
#12
F I Vos, P Merkus, E B J van Nieuwkerk, E F Hensen
In this paper, we describe the case of a 62-year-old female with recurring episodes of sudden deafness with vertigo and facial paresis. Within a month's time, this resulted in bilateral deafness and vestibular areflexia. Erroneously, the patient was diagnosed with sudden deafness of unknown origin and subsequently with neuroborreliosis (Lyme disease). The true diagnosis of relapsing polychondritis (RP) was revealed 9 months after initial presentation. The diagnostic delay is in part explained by the fact that, by definition, the disease has to relapse before the diagnosis can be made, but also by its pluriform clinical presentation...
October 8, 2016: BMJ Case Reports
https://www.readbyqxmd.com/read/28012498/three-dimensional-imaging-forced-oscillation-technique-to-assess-position-dependent-airway-obstruction-in-relapsing-polychondritis-a-case-report
#13
Takahiro Kamada, Isao Ito, Yoshihiro Kanemitsu, Susumu Sato, Hisako Matsumoto, Akio Niimi, Michiaki Mishima
Relapsing polychondritis (RP) is characterized by recurrent systemic inflammation of the cartilages and is accompanied by central airway collapse. We report a case wherein three-dimensional imaging of respiratory system resistance (Rrs) and respiratory system reactance (Xrs) by using MostGraph (CHEST M.I., Tokyo, Japan), a forced oscillation system, revealed that Rrs and Xrs in the inspiratory and expiratory phases correlated with proximal airway collapse. The degree of difference in Rrs and Xrs between the supine and sitting positions reflected airway collapse more closely than did the pulmonary function test...
January 2017: Respiratory Investigation
https://www.readbyqxmd.com/read/27920712/hypertrophic-pachymeningitis-as-an-early-manifestation-of-relapsing-polychondritis-case-report-and-review-of-the-literature
#14
Satoru Ushiyama, Tomomi Kinoshita, Yasuhiro Shimojima, Nobuhiko Ohashi, Dai Kishida, Daigo Miyazaki, Katsuya Nakamura, Yoshiki Sekijima, Shu-Ichi Ikeda
Neurological involvement in relapsing polychondritis (RP) is relatively rare. We describe the case of an 80-year-old man who presented with hypertrophic pachymeningitis (HP) together with arthritis as the first manifestation of RP. Auricular chondritis, which subsequently determined the diagnosis of RP, occurred a few weeks after the detection of HP. The neurological symptoms, as well as arthritis, were promptly improved by treatment with corticosteroids. It is generally difficult to diagnose RP in the absence of typical cartilaginous involvement; however, the present case suggests that HP may occur as an early clinical manifestation of RP...
September 2016: Case Reports in Neurology
https://www.readbyqxmd.com/read/27904200/a-case-of-relapsing-polychondritis-with-palmoplantar-pustulosis
#15
Won Joo Kwon, Min Seok Kim, Jun Yeong Park, Eun Byul Cho, Eun Joo Park, Kwang Ho Kim, Kwang Joong Kim
No abstract text is available yet for this article.
November 2016: Indian Journal of Dermatology
https://www.readbyqxmd.com/read/27886803/relapsing-polychondritis-a-2016-update-on-clinical-features-diagnostic-tools-treatment-and-biological-drug-use
#16
REVIEW
Alexis Mathian, Makoto Miyara, Fleur Cohen-Aubart, Julien Haroche, Miguel Hie, Micheline Pha, Philippe Grenier, Zahir Amoura
Relapsing polychondritis (RP) is a very rare autoimmune disease characterised by a relapsing inflammation of the cartilaginous tissues (joints, ears, nose, intervertebral discs, larynx, trachea and cartilaginous bronchi), which may progress to long-lasting atrophy and/or deformity of the cartilages. Non-cartilaginous tissues may also be affected, such as the eyes, heart, aorta, inner ear and skin. RP has a long and unpredictable course. Because no randomised therapeutic trials are available, the treatment of RP remains mainly empirical...
April 2016: Best Practice & Research. Clinical Rheumatology
https://www.readbyqxmd.com/read/27757051/prevalence-and-comorbidity-of-relapsing-polychondritis
#17
EDITORIAL
Jonas F Ludvigsson, Ronald van Vollenhoven
No abstract text is available yet for this article.
2016: Clinical Epidemiology
https://www.readbyqxmd.com/read/27728688/a-case-report-of-relapsing-polychondritis
#18
Geetha Navuduri
No abstract text is available yet for this article.
January 2016: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/27709866/relapsing-polychondritis-with-central-nervous-system-involvement-experience-of-three-different-cases-in-a-single-center
#19
Chan Hong Jeon
Relapsing polychondritis (RP) is an autoimmune disorder characterized by inflammation in cartilaginous structures including the ears, noses, peripheral joints, and tracheobronchial tree. It rarely involves the central nervous system (CNS) but diagnosis of CNS complication of RP is challenging because it can present with varying clinical features. Herein we report 3 cases of relapsing polychondritis involving CNS with distinct manifestations and clinical courses. The first patient presented with rhombencephalitis resulting in brain edema and death...
November 2016: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/27708954/relapsing-polychondritis
#20
REVIEW
Hakan Emmungil, Sibel Zehra Aydın
Relapsing polychondritis (RPC) is a unique and rarely observed autoimmune condition regarded as recurrent extensive chondritis of the auricular, nasal, and tracheal cartilages. Moreover, heart, main arteries, skin, and eyes may be involved. Several forms of clinical manifestations may be seen, and the pathogenesis still remains anonymous. A concomitant disease, particularly myelodysplasia or other systemic autoimmune disease can be detected in one-third of the patients with RPC. The treatment of RPC should be considered on personal basis and classified according to disease activity and severity...
December 2015: European Journal of Rheumatology
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