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Relapsing Polychondritis

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https://www.readbyqxmd.com/read/28093782/relapsing-polychondritis-as-an-unusual-cause-of-multiple-cranial-nerve-palsies-a-case-report
#1
Fatme Seval Ismail, Björn Enzi, Christian Boy, Annika Kowoll, Jens Eyding, Uwe Schlegel
No abstract text is available yet for this article.
January 17, 2017: Muscle & Nerve
https://www.readbyqxmd.com/read/28049117/rare-cause-of-bilateral-sudden-deafness
#2
F I Vos, P Merkus, E B J van Nieuwkerk, E F Hensen
In this paper, we describe the case of a 62-year-old female with recurring episodes of sudden deafness with vertigo and facial paresis. Within a month's time, this resulted in bilateral deafness and vestibular areflexia. Erroneously, the patient was diagnosed with sudden deafness of unknown origin and subsequently with neuroborreliosis (Lyme disease). The true diagnosis of relapsing polychondritis (RP) was revealed 9 months after initial presentation. The diagnostic delay is in part explained by the fact that, by definition, the disease has to relapse before the diagnosis can be made, but also by its pluriform clinical presentation...
October 8, 2016: BMJ Case Reports
https://www.readbyqxmd.com/read/28012498/three-dimensional-imaging-forced-oscillation-technique-to-assess-position-dependent-airway-obstruction-in-relapsing-polychondritis-a-case-report
#3
Takahiro Kamada, Isao Ito, Yoshihiro Kanemitsu, Susumu Sato, Hisako Matsumoto, Akio Niimi, Michiaki Mishima
Relapsing polychondritis (RP) is characterized by recurrent systemic inflammation of the cartilages and is accompanied by central airway collapse. We report a case wherein three-dimensional imaging of respiratory system resistance (Rrs) and respiratory system reactance (Xrs) by using MostGraph (CHEST M.I., Tokyo, Japan), a forced oscillation system, revealed that Rrs and Xrs in the inspiratory and expiratory phases correlated with proximal airway collapse. The degree of difference in Rrs and Xrs between the supine and sitting positions reflected airway collapse more closely than did the pulmonary function test...
January 2017: Respiratory Investigation
https://www.readbyqxmd.com/read/27920712/hypertrophic-pachymeningitis-as-an-early-manifestation-of-relapsing-polychondritis-case-report-and-review-of-the-literature
#4
Satoru Ushiyama, Tomomi Kinoshita, Yasuhiro Shimojima, Nobuhiko Ohashi, Dai Kishida, Daigo Miyazaki, Katsuya Nakamura, Yoshiki Sekijima, Shu-Ichi Ikeda
Neurological involvement in relapsing polychondritis (RP) is relatively rare. We describe the case of an 80-year-old man who presented with hypertrophic pachymeningitis (HP) together with arthritis as the first manifestation of RP. Auricular chondritis, which subsequently determined the diagnosis of RP, occurred a few weeks after the detection of HP. The neurological symptoms, as well as arthritis, were promptly improved by treatment with corticosteroids. It is generally difficult to diagnose RP in the absence of typical cartilaginous involvement; however, the present case suggests that HP may occur as an early clinical manifestation of RP...
September 2016: Case Reports in Neurology
https://www.readbyqxmd.com/read/27904200/a-case-of-relapsing-polychondritis-with-palmoplantar-pustulosis
#5
Won Joo Kwon, Min Seok Kim, Jun Yeong Park, Eun Byul Cho, Eun Joo Park, Kwang Ho Kim, Kwang Joong Kim
No abstract text is available yet for this article.
November 2016: Indian Journal of Dermatology
https://www.readbyqxmd.com/read/27886803/relapsing-polychondritis-a-2016-update-on-clinical-features-diagnostic-tools-treatment-and-biological-drug-use
#6
REVIEW
Alexis Mathian, Makoto Miyara, Fleur Cohen-Aubart, Julien Haroche, Miguel Hie, Micheline Pha, Philippe Grenier, Zahir Amoura
Relapsing polychondritis (RP) is a very rare autoimmune disease characterised by a relapsing inflammation of the cartilaginous tissues (joints, ears, nose, intervertebral discs, larynx, trachea and cartilaginous bronchi), which may progress to long-lasting atrophy and/or deformity of the cartilages. Non-cartilaginous tissues may also be affected, such as the eyes, heart, aorta, inner ear and skin. RP has a long and unpredictable course. Because no randomised therapeutic trials are available, the treatment of RP remains mainly empirical...
April 2016: Best Practice & Research. Clinical Rheumatology
https://www.readbyqxmd.com/read/27757051/prevalence-and-comorbidity-of-relapsing-polychondritis
#7
Jonas F Ludvigsson, Ronald van Vollenhoven
No abstract text is available yet for this article.
2016: Clinical Epidemiology
https://www.readbyqxmd.com/read/27728688/a-case-report-of-relapsing-polychondritis
#8
Geetha Navuduri
No abstract text is available yet for this article.
January 2016: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/27709866/relapsing-polychondritis-with-central-nervous-system-involvement-experience-of-three-different-cases-in-a-single-center
#9
Chan Hong Jeon
Relapsing polychondritis (RP) is an autoimmune disorder characterized by inflammation in cartilaginous structures including the ears, noses, peripheral joints, and tracheobronchial tree. It rarely involves the central nervous system (CNS) but diagnosis of CNS complication of RP is challenging because it can present with varying clinical features. Herein we report 3 cases of relapsing polychondritis involving CNS with distinct manifestations and clinical courses. The first patient presented with rhombencephalitis resulting in brain edema and death...
November 2016: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/27708954/relapsing-polychondritis
#10
REVIEW
Hakan Emmungil, Sibel Zehra Aydın
Relapsing polychondritis (RPC) is a unique and rarely observed autoimmune condition regarded as recurrent extensive chondritis of the auricular, nasal, and tracheal cartilages. Moreover, heart, main arteries, skin, and eyes may be involved. Several forms of clinical manifestations may be seen, and the pathogenesis still remains anonymous. A concomitant disease, particularly myelodysplasia or other systemic autoimmune disease can be detected in one-third of the patients with RPC. The treatment of RPC should be considered on personal basis and classified according to disease activity and severity...
December 2015: European Journal of Rheumatology
https://www.readbyqxmd.com/read/27696147/relapsing-polychondritis-a-review-and-guide-for-the-dermatologist
#11
AnneLiese Smylie, Neel Malhotra, Alain Brassard
Relapsing polychondritis, or RP, is a rare connective tissue disease characterized by relapsing-remitting destructive inflammation of the cartilaginous and other proteoglycan-rich structures in the body. Given the relatively low incidence of RP, a concise clinically relevant guide, focusing on the cutaneous manifestations of this serious disease, is lacking. In this review, we provide the dermatologist with an approach to diagnosing RP and a guide to its initial work-up, and management. We close with an overview of the currently available treatment modalities for RP...
October 1, 2016: American Journal of Clinical Dermatology
https://www.readbyqxmd.com/read/27692394/what-rheumatologists-should-know-about-orofacial-manifestations-of-autoimmune-rheumatic-diseases
#12
Aline Lauria Pires Abrão, Caroline Menezes Santana, Ana Cristina Barreto Bezerra, Rivadávio Fernandes Batista de Amorim, Mariana Branco da Silva, Licia Maria Henrique da Mota, Denise Pinheiro Falcão
Orofacial manifestations occur frequently in rheumatic diseases and usually represent early signs of disease or of its activity that are still neglected in clinical practice. Among the autoimmune rheumatic diseases with potential for oral manifestations, rheumatoid arthritis (RA), inflammatory myopathies (IM), systemic sclerosis (SSc), systemic lupus erythematosus (SLE), relapsing polychondritis (RP) and Sjögren's syndrome (SS) can be cited. Signs and symptoms such as oral hyposalivation, xerostomia, temporomandibular joint disorders, lesions of the oral mucosa, periodontal disease, dysphagia, and dysphonia may be the first expression of these rheumatic diseases...
September 2016: Revista Brasileira de Reumatologia
https://www.readbyqxmd.com/read/27552828/successful-continual-intratympanic-steroid-injection-therapy-in-a-patient-with-refractory-sensorineural-hearing-loss-accompanied-by-relapsing-polychondritis
#13
Koichiro Wasano, Shuta Tomisato, Sayuri Yamamoto, Noriomi Suzuki, Taiji Kawasaki, Kaoru Ogawa
OBJECTIVE: To report the treatment efficacy of continual intratympanic steroid injection (ITSI) therapy in a patient with refractory sensorineural hearing loss accompanied by relapsing polychondritis. PATIENT: A 49-year-old female diagnosed with relapsing polychondritis at the age of 45 years and who had been treated with corticosteroids and immunosuppressants developed sensorineural hearing loss in the left ear. INTERVENTION: Her unilateral hearing loss did not recover despite receiving one cyclophosphamide pulse treatment, one methylprednisolone pulse treatment, and weekly leukapheresis...
August 20, 2016: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/27537572/18f-fdg-pet-ct-imaging-of-relapsing-polychondritis-a-case-report
#14
Huijun Zhou, Minggang Su, Lin Li
BACKGROUND: Relapsing polychondritis (RP) is an uncommon autoimmune inflammatory disease that may affect cartilage throughout the body. CASE REPORT: We report on a case of fever of unknown origin in which 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) was performed to make a diagnosis of RP. CONCLUSION: Our case demonstrates that the use of 18F-FDG PET/CT is a useful diagnostic tool to accurately determine the extent of inflammation throughout the body which can be identified by an increased 18F-FDG uptake...
August 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27459759/-nervous-system-lesions-associated-with-relapsing-polychondritis-analysis-of-original-observations
#15
REVIEW
V I Chernyak, Savel'ev A I, I V Men'shikova, A P Pogromov
Three clinical cases are described including two of relapsing polychondritis with lesions in the central and peripheral nervous system (one of long-standing aseptic lymphocytic meningitis and one of cranial neuropathy of 2, 5, 7, and 8 pairs) and the third case of the optic nerve lesion with amblyopia. The two former cases were successfully treated with high doses of corticosteroids, the third one with moderate doses of the same medications. The data from the current literature concerning variants of clinical manifestations, methods for diagnostics and treatment of neurologic manifestations of relapsing polychondritis are discussed...
2016: Klinicheskaia Meditsina
https://www.readbyqxmd.com/read/27434790/quantitative-computed-tomography-assessment-of-air-trapping-in-relapsing-polychondritis-correlations-with-spirometric-values-erratum
#16
(no author information available yet)
No abstract text is available yet for this article.
July 2016: Journal of Computer Assisted Tomography
https://www.readbyqxmd.com/read/27418855/a-nationwide-study-of-the-epidemiology-of-relapsing-polychondritis
#17
Anna Horváth, Nóra Páll, Katalin Molnár, Tamás Kováts, György Surján, Tamás Vicsek, Péter Pollner
OBJECTIVE: Relapsing polychondritis (RP) is a rare autoimmune inflammatory disease that attacks mainly cartilaginous structures or causes serious damage in proteoglycan-rich structures (the eyes, heart, blood vessels, inner ear). This study shows results regarding the epidemiology, progression, and associations of this highly variable disease by collecting all cases from a 124-million-person-year Central European nationwide cohort. METHODS: We used the Hungarian Health Care Database to identify all persons with possible RP infection...
2016: Clinical Epidemiology
https://www.readbyqxmd.com/read/27396510/corticosteroid-therapy-for-a-patient-with-relapsing-polychondritis-complicated-by-igg4-related-disease
#18
Mari Yamasue, Shin-Ichi Nureki, Hiroyuki Matsumoto, Takamasa Kan, Takehiro Hashimoto, Ryoichi Ushijima, Yuko Usagawa, Jun-Ichi Kadota
Relapsing polychondritis (RP) is a rare systemic disorder characterized by recurrent, widespread chondritis of the auricular, nasal, and tracheal cartilages. IgG4-related disease (IgG4-RD) is a systemic immune-mediated disease characterized by the infiltration of IgG4-bearing plasma cells into systemic organs. Although 25% to 35% of patients with RP have a concurrent autoimmune disease, coexistence of RP and IgG4-RD is rare. We herein report a case of RP complicated by IgG4-RD. A 63-year-old man developed recurrent bilateral ear pain and swelling, recurrent blurred and decreased vision, and migratory multiple joint pain, sequentially within one year...
2016: Tohoku Journal of Experimental Medicine
https://www.readbyqxmd.com/read/27331771/relapsing-polychondritis-can-be-characterized-by-three-different-clinical-phenotypes-analysis-of-a-recent-series-of-142-patients
#19
Jérémie Dion, Nathalie Costedoat-Chalumeau, Damien Sène, Judith Cohen-Bittan, Gaëlle Leroux, Charlotte Dion, Camille Francès, Jean-Charles Piette
OBJECTIVE: Relapsing polychondritis (RP) is a rare condition characterized by recurrent inflammation of cartilaginous tissue and systemic manifestations. Data on this disease remain scarce. This study was undertaken to describe patient characteristics and disease evolution, identify prognostic factors, and define different clinical phenotypes of RP. METHODS: We performed a retrospective study of 142 patients with RP who were seen between 2000 and 2012 in a single center...
December 2016: Arthritis & Rheumatology
https://www.readbyqxmd.com/read/27321667/saddle-nose-with-sarcoidosis-a-great-imitator-of-relapsing-polychondritis
#20
Sanae Shimamura, Naoto Yokogawa, Kengo Murata, Tetsuo Yamaguchi, Keisuke Uchida, Yoshinobu Eishi
Sarcoidosis is a systemic granulomatous disease that can affect any organ including the nose. Nasal crusting and congestion are common nasal symptoms of sarcoidosis, whereas cases of saddle-nose deformity are rarely reported. We describe here a case of sarcoidosis that presented with saddle nose resembling relapsing polychondritis. Since sarcoidosis shares clinical features with relapsing polychondritis, the differential diagnosis of saddle nose can be challenging without a clear pathology.
June 20, 2016: Modern Rheumatology
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