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Sreenivasan Ramaswami, Joachim Behrendt, Ralf Otterpohl
Reverse osmosis (RO) and nanofiltration (NF) are among the state-of-the-art technologies for treating landfill leachates. Due to the complexity and variance in the composition of leachates, numerous combinations of multiple technologies are used for their treatment. One process chain for the treatment of raw leachate is RO followed by further concentration of RO-retentate using NF (RO-NF scheme). The aptness of this process train used by some landfill sites around the world (usually with the aim of volume reduction so as to re-inject the concentrate into the landfill) is questionable...
March 21, 2018: Membranes
Christina Pedersen, Trine Porsgaard, Maria Thomsen, Mette Marie Rosenkilde, Nikolaj Kulahin Roed
Insulin is a vital part of diabetes treatment, whereas glucagon is primarily used to treat insulin-induced hypoglycemia. However, glucagon is suggested to have a central role in the regulation of body weight, which would be beneficial for diabetic patients. Since the glucagon effect on blood glucose is known to be transient, it is relevant to investigate the pharmacodynamics of glucagon after repeated dosing. In the present study, we used telemetry to continuously measure blood glucose in streptozotocin induced diabetic Sprague-Dawley rats...
2018: PloS One
Evaggelina Papakanderaki, Konstantinos Kanakakis, Sotirios Goule, Maria Chounti, Panagiotis Hountis
Raoultella Ornithinolytica (RO) is an encapsulated, Gram- negative, nonmotile aerobic rob which was reclassified from Klepsiella genus belonging in the family of Enterobacteriaceae. It is a rare human infection and few cases have been reported in post thoracotomy patients. Here we present a case of a left lower lobectomy patient that was complicated by pleural effusion and high fever with positive sputum cultures of Raoultella Ornithinolytica and positive pleural fluid cultures of Staphylococcus hominis. It is related with aquatic life poisoning...
February 26, 2018: Monaldi Archives for Chest Disease, Archivio Monaldi Per le Malattie del Torace
Min Cheol Joo, Chul Hwan Jang, Jong Tae Park, Seung Won Choi, Seungil Ro, Min Seob Kim, Moon Young Lee
Although electrical stimulation is therapeutically applied for neural regeneration in patients, it remains unclear how electrical stimulation exerts its effects at the molecular level on spinal cord injury (SCI). To identify the signaling pathway involved in electrical stimulation improving the function of injured spinal cord, 21 female Sprague-Dawley rats were randomly assigned to three groups: control (no surgical intervention, n = 6), SCI (SCI only, n = 5), and electrical simulation (ES; SCI induction followed by ES treatment, n = 10)...
February 2018: Neural Regeneration Research
Yagiz Efe Bayiz, Mohammad Ghanaatpishe, Hosam Fathy, Bo Cheng
In this work, a multi-objective optimization framework is developed for optimizing low-Reynolds number (Re) hovering flight. This framework is then applied to compare the efficiency of rigid revolving and flapping wings with rectangular shape under varying Re and Rossby number (Ro, or aspect ratio). The proposed framework is capable of generating sets of optimal solutions and Pareto fronts for maximizing lift coefficient and minimizing power coefficient in dimensionless space, which explicitly reveal the trade off between lift generation and power consumption...
March 20, 2018: Bioinspiration & Biomimetics
Jung-Ro Yoon, Jae-Hyuk Yang
BACKGROUND: The purpose of this retrospective study was to analyze and compare the clinical and radiologic outcomes of fixed bearing ultracongruent (UC) insert total knee arthroplasty (TKA) and mobile bearing (MB) floating platform TKA using the navigation-assisted gap balancing technique with a minimum follow-up of five years. METHODS: The study retrospectively enrolled 105 patients who received the UC type fixed bearing insert (group 1) and 95 patients who received the floating platform MB insert (group 2) during the period from August 2009 to June 2012...
March 20, 2018: International Orthopaedics
Se Eun Ha, Lai Wei, Brian G Jorgensen, Moon Young Lee, Paul J Park, Sandra M Poudrier, Seungil Ro
Intestinal obstructions, that impede or block peristaltic movement, can be caused by abdominal adhesions and most gastrointestinal (GI) diseases including tumorous growths. However, the cellular remodeling mechanisms involved in, and caused by, intestinal obstructions are poorly understood. Several animal models of intestinal obstructions have been developed, but the mouse model is the most cost/time effective. The mouse model uses the surgical implantation of an intestinal partial obstruction (PO) that has a high mortality rate if it is not performed correctly...
March 5, 2018: Journal of Visualized Experiments: JoVE
Marta Sánchez-Soto, Verònica Casadó-Anguera, Hideaki Yano, Brian Joseph Bender, Ning-Sheng Cai, Estefanía Moreno, Enric I Canela, Antoni Cortés, Jens Meiler, Vicent Casadó, Sergi Ferré
The poor norepinephrine innervation and high density of Gi/o-coupled α2A - and α2C -adrenoceptors in the striatum and the dense striatal dopamine innervation have prompted the possibility that dopamine could be an effective adrenoceptor ligand. Nevertheless, the reported adrenoceptor agonistic properties of dopamine are still inconclusive. In this study, we analyzed the binding of norepinephrine, dopamine, and several compounds reported as selective dopamine D2 -like receptor ligands, such as the D3 receptor agonist 7-OH-PIPAT and the D4 receptor agonist RO-105824, to α2 -adrenoceptors in cortical and striatal tissue, which express α2A -adrenoceptors and both α2A - and α2C -adrenoceptors, respectively...
March 18, 2018: Molecular Neurobiology
D Cingolani, F Fatone, N Frison, M Spinelli, A L Eusebi
Recovery of high quality water from municipal landfill leachate was studied by three-stage disc tube reverse osmosis optimized in pilot-scale. Following UF-membrane-assisted activated sludge plant, overall 46.5 tons of leachate were post-treated in real environment and analyzed for conventional contaminants and hazardous compounds (e.g. heavy metals, boron, selenium) throughout operation of membrane system. Operating pressure ranged from 21 to 76 bar, while permeate flux varied in the range 7.1-32.5 L m-2  h-1 ...
March 15, 2018: Waste Management
Du Hyun Ro, Hyuk-Soo Han, Seong Hwan Kim, Yoon-Ho Kwak, Jae-Young Park, Myung Chul Lee
BACKGROUND: The goals of this study were (1) to document the gait pattern of patients with unilateral knee osteoarthritis (OA), (2) to determine the knee adduction moment (KAM) changes in the non-operated knee, and (3) to identify the predictors of change in KAM in the non-operated knee. METHODS: The study recruited 23 patients with advanced unilateral knee OA. The preoperative Kellgren-Lawrence (KL) grade of the non-operated knee was one or two; non-operated knee pain, rated using a numeric rating scale (NRS), was less than three out of 10 points...
March 13, 2018: Knee
Won Seon Koh, Jeong Eun Kim, Young Suck Ro, Joo Yeon Ko
BACKGROUND: Despite various treatments attempts, no prospective studies have compared the different therapeutic modalities for treatment of idiopathic guttate hypomelanosis (IGH). This study aimed to compare the efficacy of CO2 fractional laser (CO₂FL), Er:YAG fractional laser (EYFL), and 0.025% topical tretinoin for treating IGH. MATERIALS AND METHODS: A total of 122 lesions were analyzed from 18 patients (mean age, 70.00 ± 20.00 years). Treatment outcome evaluations included the visual analog scale (VAS) to assess lesion severity, investigator's global assessment (IGA) to assess the extent of improvement, and patient's satisfaction score (PSS)...
March 16, 2018: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
Yushi Uetera, Hiroshi Yasuhara, Naohito Kumada, Yoshiki Misawa, Yoshiyuki Terada, Yoshio Satou, Tamaki Suhara, Kunio Kawamura
Recently, the use of filters has come into light for sanitizing water plants. This study investigated the role of heat-tolerant ultrafilters (UFs) for the remediation of reverse osmosis (RO) plants using periodic thermal disinfection. Two completely identical RO plants (RO plants A & B) were installed in 2006 for surgical hand antisepsis in the operating theater. RO water was stored in the 300-liter storage tank and re-circulated in the 190 meter-long loop delivering water to 12 faucets in each RO plant...
March 15, 2018: PDA Journal of Pharmaceutical Science and Technology
Tae Hoon Ro, Lance Edmonds
Piriformis syndrome is an uncommon condition that causes significant pain in the posterior lower buttocks and leg due to entrapment of the sciatic nerve at the level of the piriformis muscle. In the typical anatomical presentation, the sciatic nerve exits directly ventral and inferior to the piriformis muscle and continues down the posterior leg. Several causes that have been linked to this condition include trauma, differences in leg length, hip arthroplasty, inflammation, neoplastic mass effect, and anatomic variations...
2018: Journal of Clinical Imaging Science
Marit Danielsen, Sigrid Bjørnelv, Grete Helen Bratberg, Øyvind Rø
OBJECTIVE: The need to consider gender when studying exercise in eating disorder (ED) has been underscored. The study aimed to test the psychometric properties and factor structure of the exercise and eating disorder (EED) questionnaire for males with and without ED, to highlight gender differences, and to explore issues relevant for a male version of the EED questionnaire. METHOD: This cross sectional study included 258 male participants: 55 ED patients (inpatients and outpatients) and 203 student controls...
March 14, 2018: International Journal of Eating Disorders
Pei Biao, Chen Junjie, Liu Peng, He Tao, Li Xuemei, Zhang Lin
Generally, conventional polyamide reverse osmosis (RO) membranes suffer from a low water flux and serious oil pollution in the treatment of oil saline wastewater. Here, a novel RO membrane was successfully fabricated with hyperbranched polyamidoamine (PAMAM) and trimesoyl chloride (TMC) by interfacial reaction on polysulfone ultrafiltration membrane surface. The relatively smooth and thin PAMAM and TMC crosslinking active layer on the substrate membrane endowed the composite membrane with an excellent separation performance and remarkable anti-fouling performance simultaneously...
March 14, 2018: Environmental Technology
Yoshiaki Iwase, Yoji Horie, Sawao Honda, Yusuke Daiko, Yuji Iwamoto
Polyalkoxysilsesquiazanes ([ROSi(NH)1.5 ]n , ROSZ, R = Et, nPr, iPr, nBu, sBu, nHex, sHex, cHex, decahydronaphthyl (DHNp)) were synthesized by ammonolysis at -78 °C of alkoxytrichlorosilane (ROSiCl₃), which was isolated by distillation as a reaction product of SiCl₄ and ROH. The simultaneous thermogravimetric and mass spectrometry analyses of the ROSZs under helium revealed a common decomposition reaction, the cleavage of the oxygen-carbon bond of the RO group to evolve alkene as a main gaseous species formed in-situ, leading to the formation of microporous amorphous Si-O-N at 550 °C to 800 °C...
March 13, 2018: Materials
Bradley Wills, Sung Ro Lee, Parke William Hudson, Bahman SahraNavard, Cesar de Cesar Netto, Sameer Naranje, Ashish Shah
BACKGROUND: Calcaneal osteotomy is a commonly used surgical option for the correction of hindfoot malalignment. A previous cadaveric study described a neurological "safe zone" for calcaneal osteotomy. We performed a retrospective chart review to evaluate the presence of neurological injuries following calcaneal osteotomies and the location of the osteotomy in relation to the reported safe zone. METHODS: In this retrospective study, we reviewed charts of patients who underwent calcaneal osteotomy at our institution from 2011 to 2015...
March 1, 2018: Foot & Ankle Specialist
Jens Wollebaek, Jan Heggenes, Knut H Roed
Ecotype variation in species exhibiting different life history strategies may reflect heritable adaptations to optimize reproductive success, and potential for speciation. Traditionally, ecotypes have, however, been defined by morphometrics and life history characteristics, which may be confounded with individual plasticity. Here, we use the widely distributed and polytypic freshwater fish species brown trout ( Salmo trutta ) as a model to study piscivorous life history and its genetic characteristics in environmentally contrasting habitats; a large lake ecosystem with one major large and stable tributary, and several small tributaries...
March 2018: Ecology and Evolution
Ro-Ting Lin, Cheng-Kuan Lin, David C Christiani, Ichiro Kawachi, Yawen Cheng, Stéphane Verguet, Simcha Jong
A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper.
March 12, 2018: Scientific Reports
Allie J Widman, Lori L McMahon
Low-dose ketamine, an open-channel N -methyl d-aspartate receptor (NMDAR) antagonist, mediates rapid antidepressant effects in humans that are mimicked in preclinical rodent models. Disinhibition of pyramidal cells via decreased output of fast-spiking GABAergic interneurons has been proposed as a key mechanism that triggers the antidepressant response. Unfortunately, to date, disinhibition has not been directly demonstrated. Furthermore, whether disinhibition is a common mechanism shared among other antagonists with rapid antidepressant properties in humans has not been investigated...
March 12, 2018: Proceedings of the National Academy of Sciences of the United States of America
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