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https://www.readbyqxmd.com/read/28088468/hypothalamic-effects-of-thyroid-hormone
#1
Zhi Zhang, Anita Boelen, Peter H Bisschop, Andries Kalsbeek, Eric Fliers
Thyroid hormone (TH) is a key driver of metabolism in mammals. Plasma concentrations of TH are kept within a narrow range by negative feedback regulation in the hypothalamus-pituitary-thyroid (HPT) axis. Plasma TH concentrations are an important determinant of metabolic processes in liver and brown adipose tissue (BAT). In addition to endocrine effects of TH derived from the circulation, recent studies have demonstrated additional neural routes for intrahypothalamic thyroid hormone to regulate metabolism in liver and BAT via the sympathetic and parasympathetic branch of the autonomic nervous system (ANS)...
January 11, 2017: Molecular and Cellular Endocrinology
https://www.readbyqxmd.com/read/28087567/interventions-to-increase-adherence-to-therapeutic-exercise-in-older-adults-with-low-back-pain-and-or-hip-knee-osteoarthritis-a-systematic-review-and-meta-analysis
#2
Philippa J A Nicolson, Kim L Bennell, Fiona L Dobson, Ans Van Ginckel, Melanie A Holden, Rana S Hinman
OBJECTIVE: To evaluate whether interventions aimed at increasing adherence to therapeutic exercise increase adherence greater than a contextually equivalent control among older adults with chronic low back pain and/or hip/knee osteoarthritis. DESIGN: A systematic review and meta-analysis. DATA SOURCES: Five databases (MEDLINE (PubMed), CINAHL, SportDISCUS (EBSCO), Embase (Ovid) and Cochrane Library) were searched until 1 August 2016. ELIGIBILITY CRITERIA FOR SELECTING STUDIES: Randomised controlled trials that isolated the effects of interventions aiming to improve adherence to therapeutic exercise among adults ≥45 years of age with chronic low back pain and/or hip/knee osteoarthritis were included...
January 13, 2017: British Journal of Sports Medicine
https://www.readbyqxmd.com/read/28079874/cerebral-modulation-of-the-autonomic-nervous-system-in-term-infants
#3
N Schneebaum Sender, R B Govindan, M T Whitehead, A N Massaro, M Metzler, J Wang, Y I Cheng, A J du Plessis
OBJECTIVE: Central topography of autonomic nervous system (ANS) function has yet to be fully deciphered. In adults it has been shown to lateralize sympathetic and parasympathetic influence predominantly to the right and left cerebral hemispheres, respectively. We examined functional topography of central ANS in newborn subjects utilizing spectral analysis of heart rate variability (HRV), an established measure of ANS function. STUDY DESIGN: We studied newborns with hypoxic-ischemic encephalopathy participating in a prospective study undergoing a therapeutic hypothermia protocol...
January 12, 2017: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/28076441/effects-of-an-integrated-fast-track-rehabilitation-service-for-multi-trauma-patients-a-non-randomized-clinical-trial-in-the-netherlands
#4
Ans I E Bouman, Bea Hemmen, Silvia M A A Evers, Henk van de Meent, Ton Ambergen, Pieter E Vos, Peter R G Brink, Henk A M Seelen
OBJECTIVES: The effects on health related outcomes of a newly-developed rehabilitation program, called 'supported Fast Track multi-trauma rehabilitation service' (Fast Track), were evaluated in comparison with conventional trauma rehabilitation service (Care as Usual). METHODS: Prospective, multi-center, non-randomized controlled study. Between 2009 and 2012, 132 adult multi-trauma patients were included: 65 Fast Track and 67 Care as Usual patients with an Injury Severity Score ≥16, complex multiple injuries in several extremities or complex pelvic and/or acetabulum fractures...
2017: PloS One
https://www.readbyqxmd.com/read/28070755/social-adversity-and-antisocial-behavior-mediating-effects-of-autonomic-nervous-system-activity
#5
Shawn E Fagan, Wei Zhang, Yu Gao
The display of antisocial behaviors in children and adolescents has been of interest to criminologists and developmental psychologists for years. Exposure to social adversity is a well-documented predictor of antisocial behavior. Additionally, measures of autonomic nervous system (ANS) activity, including heart rate variability (HRV), pre-ejection period (PEP), and heart rate, have been associated with antisocial behaviors including rule-breaking and aggression. Social neuroscience research has begun to investigate how neurobiological underpinnings affect the relationship between social adversity and antisocial/psychopathic behavior in children and adolescents...
January 9, 2017: Journal of Abnormal Child Psychology
https://www.readbyqxmd.com/read/28069130/comparison-of-gel-properties-and-biochemical-characteristics-of-myofibrillar-protein-from-bighead-carp-aristichthys-nobilis-affected-by-frozen-storage-and-a-hydroxyl-radical-generation-oxidizing-system
#6
Han Lu, Longteng Zhang, Qingzheng Li, Yongkang Luo
We wanted to clarify whether gel properties can be affected by in vivo or in vitro myofibrillar protein oxidation and, thus, to provide relevant information and a scientific foundation for the processing of gel products. To accomplish this, we measured the changes in sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE), total disulfide (SS) content, surface hydrophobicity (So-ANS), carbonyl content, and gel texture and water-holding capacity (WHC) of isolated myofibrillar protein from bighead carp fillets during frozen storage and under different H2O2 concentrations, which were used to represent in vivo and in vitro conditions, respectively...
May 15, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28068528/a-dissociation-between-small-and-large-numbers-in-young-children-s-ability-to-solve-for-x-in-non-symbolic-math-problems
#7
Melissa M Kibbe, Lisa Feigenson
Solving for an unknown addend in problems like 5+x=17 is challenging for children. Yet, previous work (Kibbe & Feigenson, 2015) found that even before formal math education, young children, aged 4- to 6-years, succeeded when problems were presented using non-symbolic collections of objects rather than symbolic digits. This reveals that the Approximate Number System (ANS) can support pre-algebraic intuitions. Here, we asked whether children also could intuitively "solve for x" when problems contained arrays of four or fewer objects that encouraged representations of individual objects instead of ANS representations...
January 6, 2017: Cognition
https://www.readbyqxmd.com/read/28064280/compliance-with-dietary-guidelines-and-increased-fortification-can-double-vitamin-d-intake-a-simulation-study
#8
Rajwinder K Harika, Mariska Dötsch-Klerk, Peter L Zock, Ans Eilander
OBJECTIVE: The study aimed to determine the potential of compliance with Food-Based Dietary Guidelines (FBDG) and increased vitamin D fortification to meet the recommended intake level of vitamin D at 10 µg/day based on minimal exposure to sunlight. METHODS: The main dietary sources of vitamin D were derived from national dietary surveys in adults from United Kingdom (UK) (n = 911), Netherlands (NL) (n = 1,526), and Sweden (SE) (n = 974). The theoretical increase in population vitamin D intake was simulated for the following: (1) compliance with FBDG, (2) increased level of vitamin D in commonly fortified foods, and (3) combination of both...
January 7, 2017: Annals of Nutrition & Metabolism
https://www.readbyqxmd.com/read/28062609/commentary
#9
W W M Pim Pijnappel, Pieter A van Doorn, Ans T van der Ploeg
No abstract text is available yet for this article.
January 2017: Clinical Chemistry
https://www.readbyqxmd.com/read/28058144/failed-mask-ventilation-due-to-air-leakage-around-the-orbit-in-a-patient-with-a-history-of-radical-maxillofacial-surgery-with-orbital-exenteration
#10
Reiko Horishita, Kenji Kayashima
A 72-year-old male (height: 160 cm, weight: 53 kg) was scheduled to undergo left renal and male with ans uterine tract resection. The patient had previously undergone right radical maxillofacial surgery with orbital exenteration 14 years before the present operation to treat squamous cell carcinoma of the right maxillary sinus, with tumour invasion to the orbital floor. An anaesthesiologist encountered difficulty in performing mask ventilation during the induction of anaesthesia in the patient, despite a good mask fit on the face, because the adhesive tape around the orbit had moved...
December 2016: Turkish Journal of Anaesthesiology and Reanimation
https://www.readbyqxmd.com/read/28047877/su-c-206-05-pixel-wise-calculation-of-noise-statistics-on-iterative-ct-reconstruction-from-a-single-scan
#11
T Wang, L Zhu
PURPOSE: As iterative CT reconstruction continues to advance, the spatial distributions of noise standard deviation (STD) and accurate noise power spectrum (NPS) on reconstructed CT images become more important for method evaluation ans algorithm parameters settings. Using data of a single scan, we propose a practical method for pixel-wise noise statistics calculation on iterative CT reconstruction image, which enables accurate calculation of noise STD for each pixel and NPS without stationary noise assumption...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046123/neo-epitopes-generated-on-hydroxyl-radical-modified-glycatedigg-have-role-in-immunopathology-of-diabetes-type-2
#12
Sidra Islam, Abdul Rouf Mir, Alok Raghav, Farzana Khan, Khursheed Alam, Asif Ali, Moin Uddin
Glycoxidation plays a crucial role in diabetes and its associated complications. Among the glycoxidation agents, methylglyoxal (MG) is known to have very highglycationpotential witha concomitant generation of reactive oxygen species (ROS) during its synthesis and degradation. The presentstudy probes the MG and ROSinduced structural damage to immunoglobulin G (IgG) and alterations in its immunogenicity in diabetes type 2 patients (T2DM). Human IgG was first glycated with MG followed by hydroxyl radical (OH•) modification...
2017: PloS One
https://www.readbyqxmd.com/read/28042256/are-temporary-anchorage-devices-truly-effective-in-the-treatment-of-skeletal-open-bites
#13
Hakan Turkkahraman, Mehmet Sarioglu
OBJECTIVE: The aims of this study were to evaluate the effects of temporary anchorage devices (TADs) in the treatment of skeletal open bites and to compare the results with untreated controls. MATERIALS AND METHODS: A total of forty patients with skeletal anterior open bites were assigned to two groups of twenty each. The mean chronological age for the treatment group (14 female, 6 male) was 16.68 ± 2.80 years old, compared with 16.63 ± 2.83 years old for the control group (11 female, 9 male)...
October 2016: European Journal of Dentistry
https://www.readbyqxmd.com/read/28042190/respiratory-sinus-arrhythmia-and-heart-period-in-infancy-as-correlates-of-later-oppositional-defiant-and-callous-unemotional-behaviors
#14
Nicholas J Wagner, W Roger Mills-Koonce, Michael T Willoughby, Cathi B Propper, Peter D Rehder, Noa Gueron-Sela
Extant literature suggests that oppositional defiant (ODD) and callous-unemotional (CU) behaviors in childhood and adolescence are associated with distinct patterns of psychophysiological functioning and that individual differences in these patterns have implications for developmental pathways to disorder. Very little is known about the associations between psychophysiological functioning in infancy and later ODD and CU behaviors. This study examined associations between basal autonomic nervous system (ANS) functioning in infancy and ODD and CU behaviors in later childhood...
January 2017: International Journal of Behavioral Development
https://www.readbyqxmd.com/read/28041676/autonomic-function-in-adults-with-allergic-rhinitis-and-its-association-with-disease-severity-and-duration
#15
Min Hee Kim, Eun Ji Choi, Bo-Hyoung Jang, Kyu Seok Kim, Seoung-Gyu Ko, Inhwa Choi
BACKGROUND: The association between allergic rhinitis (AR) and the autonomic nervous system (ANS) has recently received substantial attention. However, no studies have assessed how the heart rate variability (HRV) parameters are associated with duration and disease severity in AR. OBJECTIVE: To compare the difference in autonomic conditions among individuals with AR of various durations and severities and healthy controls. METHODS: We divided individuals with AR into subgroups based on duration and severity of disease...
December 29, 2016: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/28039546/the-relationship-between-lateral-displacement-of-the-mandible-and-scoliosis
#16
Azusa Nakashima, Hiroyuki Nakano, Tomohiro Yamada, Kazuya Inoue, Goro Sugiyama, Wataru Kumamaru, Yasumichi Nakajima, Tomoki Sumida, Takeshi Yokoyama, Katsuaki Mishiama, Yoshihide Mori
OBJECTIVES: Idiopathic scoliosis is an orthopaedic disease of childhood, with onset and progress occurring until adolescence. Here, the relationship between lateral displacement of the mandible and scoliosis was analysed quantitatively. METHODS: Seventy-nine non-syndromic Japanese patients (18 men, 61 women), who were diagnosed with jaw deformities and underwent surgical orthognathic treatment at Kyushu University Hospital from January 2011 to August 2014, were enrolled...
December 30, 2016: Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28038426/oxidized-epigallocatechin-gallate-inhibited-lysozyme-fibrillation-more-strongly-than-the-native-form
#17
Ting-Ting An, Shuang Feng, Cheng-Ming Zeng
Epigallocatechin gallate (EGCG), the most abundant flavanoid in green tea, is currently being evaluated in the clinic due to its benefits in the treatment of amyloid disorders. Its anti-amyloidogenic effect has been attributed to direct interaction of the intact molecule with misfolded polypeptides. In addition, antioxidant activity is also involved in the anti-amyloidogenic role. The detailed molecular mechanism is still unclear and requires further investigation. In the present study, the kinetics of EGCG oxidation and the anti-amyloidogenic effect of the resultant oxidation substances have been examined...
December 21, 2016: Redox Biology
https://www.readbyqxmd.com/read/28028160/predictive-value-of-mri-features-for-development-of-radiographic-osteoarthritis-in-a-cohort-of-participants-with-pre-radiographic-knee-osteoarthritis-the-check-study
#18
Kim van Oudenaarde, Björn Jobke, Ans C M Oostveen, Annekarien C A Marijnissen, Ron Wolterbeek, Janet Wesseling, Sita M A Bierma-Zeinstra, Hans L Bloem, Monique Reijnierse, Margreet Kloppenburg
OBJECTIVE: To determine whether MRI features are associated with development of radiographic knee OA and can be used as a predictive tool in early knee OA. METHODS: In 148 participants of the Cohort Hip and Cohort Knee study (mean age 56 years, 78% women), with a Kellgren Lawrence (KL) score ⩽1, we obtained semi-quantitatively scored knee MRI scans and radiographs at baseline. After 5 years, we determined the development of radiographic knee OA (KL ⩾2). We calculated odds ratios (ORs), with 95% CIs adjusted for age, sex and BMI, to identify MRI features associated with OA development...
January 2017: Rheumatology
https://www.readbyqxmd.com/read/28024268/validation-of-autonomic-and-endocrine-reactivity-to-a-laboratory-stressor-in-young-children
#19
Leslie E Roos, Ryan J Giuliano, Kathryn G Beauchamp, Megan Gunnar, Brigette Amidon, Philip A Fisher
The validation of laboratory paradigms that reliably induce a stress response [including hypothalamic-pituitary-adrenal (HPA) axis and autonomic nervous system (ANS) activation], is critical for understanding how children's stress-response systems support emotional and cognitive function. Early childhood research to date is markedly limited, given the difficulty in establishing paradigms that reliably induce a cortisol response. Furthermore, research to date has not included a control condition or examined concurrent ANS reactivity...
November 29, 2016: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/28012740/ignitability-of-crude-oil-and-its-oil-in-water-products-at-arctic-temperature
#20
Raymond T Ranellone, Panyawat Tukaew, Xiaochuan Shi, Ali S Rangwala
A novel platform and procedure were developed to characterize the ignitability of Alaska North Slope (ANS) crude oil and its water-in-oil products with water content up to 60% at low temperatures (-20-0°C). Time to ignition, critical heat flux, in-depth temperature profiles were investigated. It was observed that a cold boundary and consequent low oil temperature increased the thermal inertia of the oil/mixture and consequently the time to sustained ignition also increased. As the water content in the ANS water-in-oil mixture increased, the critical heat flux for ignition was found to increase...
December 21, 2016: Marine Pollution Bulletin
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