keyword
MENU ▼
Read by QxMD icon Read
search

Osteointegration

keyword
https://www.readbyqxmd.com/read/28532663/recent-developments-in-drug-eluting-devices-with-tailored-interfacial-properties
#1
REVIEW
Eva Sanchez-Rexach, Emilio Meaurio, Jose-Ramon Sarasua
Drug eluting devices have greatly evolved during past years to become fundamental products of great marketing importance in the biomedical field. There is currently a large diversity of highly specialized devices for specific applications, making the development of these devices an exciting field of research. The replacement of the former bare metal devices by devices loaded with drugs allowed the sustained and controlled release of drugs, to achieve the desired local therapeutic concentration of drug. The newer devices have been "engineered" with surfaces containing micro- and nanoscale features in a well-controlled manner, that have shown to significantly affect cellular and subcellular function of various biological systems...
May 4, 2017: Advances in Colloid and Interface Science
https://www.readbyqxmd.com/read/28531878/effect-of-hierarchical-pore-structure-on-alp-expression-of-mc3t3-e1-cells-on-bioglass-films
#2
Cuixia Yu, Junjun Zhuang, Lingqing Dong, Kui Cheng, Wenjian Weng
Hierarchical porous bioglass films on the tantalum were designed to enhance osteointegration of metallic implants. The films were prepared by a sol-gel method using P123 as the mesopore template and polystyrene microsphere as the nanopore template. The films with 5.4nm mesopores and 100nm nanopores (MBG-100) elicited an obviously elongated morphology of the cultured MC3T3-E1 cells, as a result, a higher alkaline phosphatase level was expressed. It is suggested that the nanopores play an important role in regulating cellular behavior by initial protein adsorption through nanopore curvatures...
May 8, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/28506299/developmental-hip-dysplasia-treated-by-total-hip-arthroplasty-using-a-cementless-wagner-cone-stem-in-young-adult-patients-with-a-small-physique
#3
Ping Zhen, Jun Liu, Hao Lu, Hui Chen, Xusheng Li, Shenghu Zhou
BACKGROUND: Developmental hip dysplasia (DDH) may lead to severe acetabular and femoral abnormalities that can render total hip arthroplasty (THA) challenging, especially in DDH patients with a small physique. Most conventional cemented or cementless femoral components are often difficult to implant in the narrow femoral canal and require slight version correction during surgery. The aim of this study was to present the mid-term results of THA in the treatment of DDH patients with a small physique using a cementless Wagner cone prosthesis (Zimmer®, US)...
May 15, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28401197/platelet-rich-fibrin-prf-in-implants-dentistry-in-combination-with-new-bone-regenerative-flapless-technique-evolution-of-the-technique-and-final-results
#4
Antonio Cortese, Giuseppe Pantaleo, Massimo Amato, Candace M Howard, Lorenzo Pedicini, Pier Paolo Claudio
Most common techniques for alveolar bone augmentation are guided bone regeneration (GBR) and autologous bone grafting. GBR studies demonstrated long-term reabsorption using heterologous bone graft. A general consensus has been achieved in implant surgery for a minimal amount of 2 mm of healthy bone around the implant. A current height loss of about 3-4 mm will result in proper deeper implant insertion when alveolar bone expansion is not planned because of the dome shape of the alveolar crest. To manage this situation a split crest technique has been proposed for alveolar bone expansion and the implants' insertion in one stage surgery...
January 2017: Open Medicine (Warsaw, Poland)
https://www.readbyqxmd.com/read/28386803/bioactivity-and-osteointegration-of-hydroxyapatite-coated-stainless-steel-and-titanium-wires-used-for-intramedullary-osteosynthesis
#5
Arnold V Popkov, Elena N Gorbach, Natalia A Kononovich, Dmitry A Popkov, Sergey I Tverdokhlebov, Evgeniy V Shesterikov
A lot of research was conducted on the use of various biomaterials in orthopedic surgery. Our study investigated the effects of nanostructured calcium-phosphate coating on metallic implants introduced into the bone marrow canal. Stainless steel or titanium 2-mm wires (groups 1 and 2, respectively), and hydroxyapatite-coated stainless steel or titanium wires of the same diameter (groups 3 and 4, respectively) were introduced into the tibial bone marrow canal of 20 dogs (each group = 5 dogs). Hydroxyapatite coating was deposited on the wires with the method of microarc oxidation...
April 6, 2017: Strategies in Trauma and Limb Reconstruction
https://www.readbyqxmd.com/read/28374348/corr-insights-%C3%A2-use-of-compressive-osteointegration-endoprostheses-for-massive-bone-loss-from-tumor-and-failed-arthroplasty-a-viable-option-in-the-upper-extremity
#6
Patrick J Boland
No abstract text is available yet for this article.
June 2017: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/28366746/acetabular-bone-defects-in-tha-revision-reconstruction-using-morsellised-virus-inactivated-bone-allograft-and-reinforcement-ring-seven-year-outcomes-in-95-patients
#7
G Villatte, R Erivan, G Salles, B Pereira, M Galvin, S Descamps, S Boisgard
BACKGROUND: Acetabular cup loosening is among the main reasons for revision total hip arthroplasty (THA). The implantation of a cryopreserved morsellised bone allograft is a reference method for filling bone defects. However, the outcomes of bone grafts treated with viral inactivation and secured into the host bone (notably using a reinforcement device) are unclear. We therefore retrospectively reviewed cases of acetabular revision with morsellised bone allograft implanted into a reinforcement ring for acetabular revision to assess: 1) clinical survival of the acetabular implant (time to new revision with acetabular component removal), 2) radiological implant survival, 3) and bone graft osseointegration evaluated using Oswestry's criteria...
March 30, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/28359508/functional-chest-wall-reconstruction-with-a-biomechanical-three-dimensionally-printed-implant
#8
Javier Moradiellos, Sergio Amor, Mar Córdoba, Gaetano Rocco, Mercedes Vidal, Andrés Varela
Chest wall resection and reconstruction for neoplastic diseases has unique oncologic, structural, and functional challenges. In a young and fit patient with a mediastinal mass and extensive anterior chest wall invasion, purely structural solutions were deemed insufficient. We hereby present a novel three-dimensionally printed patient-specific titanium implant of sternum and ribs. This osteointegrable implant was designed with biomechanical capabilities using a unique "Greek wave" folding pattern. Postoperative dynamic computed tomography showed that the implant allowed for controlled flexing during the respiratory cycle...
April 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28341184/global-fit-concept-in-revision-hip-arthroplasty-for-cementless-press-fit-femoral-stems
#9
F Canovas, P LeBeguec, J Batard, F Gaillard, L Dagneaux
A revision stem may be required after a femoral extended trochanteric osteotomy (ETO) is made during revision hip arthroplasty. The two main complications of straight cementless femoral stems are subsidence due to inadequate osteointegration and stress-shielding. We will describe an original revision method with ETO that uses a straight cementless stem. The goal of this method was to achieve the most extensive press-fit possible during stem implantation to improve the transmission of stresses to the bone and to prevent reduction in bone density...
March 21, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/28323714/osteointegration-and-resorption-of-intravertebral-and-extravertebral-calcium-phosphate-cement
#10
Roman Klein, Ralf Tetzlaff, Christel Weiss, Meike-Kristina Schäfer, Michael Tanner, Bernd Wiedenhöfer, Ingo Grafe, Peter-Jürgen Meeder, Gerd Noeldge, Peter P Nawroth, Christian Kasperk
STUDY DESIGN: Eleven patients with painful osteoporotic vertebral fractures who underwent kyphoplasty using calcium phosphate (CaP) cement were followed up for 1 week, 1, 2, and 3 years in a monocentric, nonrandomized, noncontrolled retrospective trial. OBJECTIVE: This study investigates long-term radiomorphologic features of intraosseous CaP cement implants and of extraosseous CaP cement leakages for up to 3 years after implantation by kyphoplasty. SUMMARY OF BACKGROUND DATA: Kyphoplasty is frequently used for the treatment of painful osteoporotic fractures...
April 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28321783/biological-and-mechanical-effects-of-micro-nanostructured-titanium-surface-on-an-osteoblastic-cell-line-in-vitro-and-osteointegration-in-vivo
#11
Jingzu Hao, Ying Li, Baoe Li, Xiaolin Wang, Haipeng Li, Shimin Liu, Chunyong Liang, Hongshui Wang
Hybrid micro-nanostructure implant surface was produced on titanium (Ti) surface by acid etching and anodic oxidation to improve the biological and mechanical properties. The biological properties of the micro-nanostructure were investigated by simulated body fluid (SBF) soaking test and MC3T3-E1 cell co-culture experiment. The cell proliferation, spreading, and bone sialoprotein (BSP) gene expression were examined by MTT, SEM, and reverse transcription-polymerase chain reaction (RT-PCR), respectively. In addition, the mechanical properties were evaluated by instrumented nanoindentation test and friction-wear test...
March 20, 2017: Applied Biochemistry and Biotechnology
https://www.readbyqxmd.com/read/28300879/behavior-study-of-the-doped-castor-bean-polymer-rod-with-bioactive-glass-and-hidroxyapatite-in-mice-femur-medullary-canal
#12
Viviani Teixeira Dos Santos, Gilberto Gonçalves Facco, Hudman Cunha Ortiz, Iandara Schettert da Silva
Purpose To evaluate the polymer doped rods behavior with bioactive glass and hydroxyapatite for possible application as a fracture fixing method. Methods Twenty eight Rattus norvegicus Wistar underwent bone defect for access to the femoral medullary canal and distributed into three experimental groups: group A - doped castor bean polymer with bioactive glass; group B - castor bean polymer and; group C - castor bean polymer doped with bioactive glass and hydroxyapatite. After 15 and 60 evaluation days, the femurs were removed and sent for histology and scanning electron microscopy...
February 2017: Acta Cirúrgica Brasileira
https://www.readbyqxmd.com/read/28293511/de-novo-reconstruction-of-a-hybrid-patella-by-staged-fabrication-of-a-microvascular-bone-transplant-with-an-osteointegrated-prosthetic-socket
#13
Goetz A Giessler, Christian Hendrich
Total patellectomy is sometimes unavoidable but usually results in severely impaired function, pain, and instability in the affected knee. Any patellar prosthetic solutions rely on a certain amount of remaining bone and therefore are not applicable after total patellectomy. Traditionally, reconstruction of a neopatella by avascular or allogeneic bone grafts is hampered by mechanical failure, resorption, or infection. We developed a new, 3-stage approach to reconstruct a hybrid patella composed of a revascularized scapula tip transplant fabricated with a prosthetic socket...
December 2016: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/28228785/mesenchymal-stem-cells-in-post-surgical-cavities-of-large-maxillary-bone-lesions
#14
Roberto Bertolai, Carlo Catelani, Mattia Signorini, Alessandro Rossi, Domenico Giannini
BACKGROUND: Recent studies have highlighted that MSCs are capable of regenerating large bone defects when used in combination with bone substitutes and increasing allo-graft osteointegration. We investigated the hypothesis that autologous MSCs may lead to increased bone regeneration and reduced healing time in post-surgical cavities of large maxillary bone lesions. METHODS: This study involved 10 patients (TEST GROUP) (6 males and 4 females). All patients had expansive mandibular lesions larger than 3 cm...
September 2016: Clinical Cases in Mineral and Bone Metabolism
https://www.readbyqxmd.com/read/28221007/ionic-colloidal-molding-as-a-biomimetic-scaffolding-strategy-for-uniform-bone-tissue-regeneration
#15
Jian Zhang, Jinpeng Jia, Jimin P Kim, Hong Shen, Fei Yang, Qiang Zhang, Meng Xu, Wenzhi Bi, Xing Wang, Jian Yang, Decheng Wu
Inspired by the highly ordered nanostructure of bone, nanodopant composite biomaterials are gaining special attention for their ability to guide bone tissue regeneration through structural and biological cues. However, bone malformation in orthopedic surgery is a lingering issue, partly due to the high surface energy of traditional nanoparticles contributing to aggregation and inhomogeneity. Recently, carboxyl-functionalized synthetic polymers have been shown to mimic the carboxyl-rich surface motifs of non-collagenous proteins in stabilizing hydroxyapatite and directing intrafibrillar mineralization in-vitro...
May 2017: Advanced Materials
https://www.readbyqxmd.com/read/28194875/nanophase-bone-substitute-for-craniofacial-load-bearing-application-pilot-study-in-the-rodent
#16
Jonathan Z Baskin, Yohannes Soenjaya, James McMasters, Alvin Ko, Amit Vasanji, Nathan Morris, Steven J Eppell
An exploratory pilot study shows that a rodent mandibular defect model is useful in determining the biological response to a nanophase collagen/apatite composite designed as a biomimetic load-bearing bone substitute. Using a critical size defect, eight groups of rats (n = 3) were implanted with four renditions of the nanophase bone substitute (NBS) biomaterial. Each rendition was tested with and without recombinant human bone morphogenetic protein 2 (BMP2). NBS biomaterial renditions were: baseline, hyper-densified, d-ribose crosslinked, and d-ribose crosslinked and hyper-densified...
February 14, 2017: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/28183675/mechanistic-investigation-on-microbial-toxicity-of-nano-hydroxyapatite-on-implant-associated-pathogens
#17
K Baskar, T Anusuya, G Devanand Venkatasubbu
The use of atomic scale inorganic nanoparticles (NPs) to fight against pathogenic microorganisms is a recent trend in biomedical area which overcomes the limitations of organic compounds in terms of stability, shelf life and bioactivity. One such Calcium phosphate based biomaterial is hydroxyapatite (HA), considered as potential bioactive compound with excellent biocompatibility, osteointegrity and biodegradability. Osteomyelitis, the implant associated infection, is the major problem worldwide responsible for the majority of implant failure cases...
April 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28130134/nanoceramics-on-osteoblast-proliferation-and-differentiation-in-bone-tissue-engineering
#18
REVIEW
Sai Nievethitha Sethu, Subhapradha Namashivayam, Saravanan Devendran, Selvamurugan Nagarajan, Wei-Bor Tsai, Srinivasan Narashiman, Murugesan Ramachandran, Moorthi Ambigapathi
Bone, a highly dynamic connective tissue, consist of a bioorganic phase comprising osteogenic cells and proteins which lies over an inorganic phase predominantly made of CaPO4 (biological apatite). Injury to bone can be due to mechanical, metabolic or inflammatory agents also owing pathological conditions like fractures, osteomyelitis, osteolysis or cysts may arise in enameloid, chondroid, cementum, or chondroid bone which forms the intermediate tissues of the body. Bone tissue engineering (BTE) applies bioactive scaffolds, host cells and osteogenic signals for restoring damaged or diseased tissues...
May 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28116421/-experimental-study-of-double-root-implantation-with-the-aid-of-template-in-rabbits
#19
Hai-Yan Xu, Qing Zhang, Li-Hua Fang, Jia You
PURPOSE: To evaluate the feasibility of double-root implantation with the aid of template. METHODS: Implant templates were fabricated based on CT data from the tibia of 12 rabbits. 12 double-root implants were placed in the tibia of rabbits under the guidance of implant templates, and single-root implants were placed in contralateral tibia of the same rabbits. Rabbits were sacrificed at 8 and 12 weeks. Implant mobility was checked directly. Specimens were examined by X-ray to measure bone gray value using Image Pro-Plus6...
October 2016: Shanghai Kou Qiang Yi Xue, Shanghai Journal of Stomatology
https://www.readbyqxmd.com/read/28111942/osteogenesis-catalyzed-by-titanium-supported-silver-nanoparticles
#20
Huiliang Cao, Wenjie Zhang, Fanhao Meng, Jinshu Guo, Donghui Wang, Shi Qian, Xinquan Jiang, Xuanyong Liu, Paul K Chu
Silver nanoparticles (Ag NPs) were widely explored for antimicrobial applications, whereas the translation into drugs and implantable antibacterial devices provoked serious concerns about their potential cytotoxicity. Herein, Ag NPs with diameters ranging from 4 to 19 nm were in situ fabricated and immobilized on titanium by using a plasma immersion ion implantation process. The particles have a population-dependent capability in activating the integrin α5 orchestrated MAPK/ERK signal cascade of osteoblast differentiation in rat bone marrow stem cells (BMSCs), and promoting osteointegration of titanium...
February 2, 2017: ACS Applied Materials & Interfaces
keyword
keyword
7659
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"