keyword
MENU ▼
Read by QxMD icon Read
search

Liposarcoma

keyword
https://www.readbyqxmd.com/read/28098568/giant-retroperitoneal-dedifferentiated-liposarcoma
#1
Kemal Beksac, Bulent Aksel, Fisun Ardic Yukruk, Olcay Kandemir
INTRODUCTION: Liposarcoma is the most frequent type of retroperitoneal sarcomas. Dedifferentiated liposarcoma is the least common subtype and is an extremely rare tumor. CASE REPORT: We present the case of a 53-year-old male who was referred with a giant retroperitoneal mass. The patients' mass was deemed unresectable by the previous institution and received chemotherapy with no benefit. We macroscopically removed the 38x32 cm mass with right nefrectomy. Pathological examination revealed dedifferentiated liposarcoma...
January 16, 2017: Annali Italiani di Chirurgia
https://www.readbyqxmd.com/read/28096721/current-concepts-in-non-gastrointestinal-stromal-tumor-soft-tissue-sarcomas-a-primer-for-radiologists
#2
REVIEW
Akshay D Baheti, Jyothi P Jagannathan, Ailbhe O'Neill, Harika Tirumani, Sree Harsha Tirumani
Non-gastrointestinal stromal tumor (GIST) soft tissue sarcomas (STSs) are a heterogeneous group of neoplasms whose classification and management continues to evolve with better understanding of their biologic behavior. The 2013 World Health Organization (WHO) has revised their classification based on new immunohistochemical and cytogenetic data. In this article, we will provide a brief overview of the revised WHO classification of soft tissue tumors, discuss in detail the radiology and management of the two most common adult non-GIST STS, namely liposarcoma and leiomyosarcoma, and review some of the emerging histology-driven targeted therapies in non-GIST STS, focusing on the role of the radiologist...
January 2017: Korean Journal of Radiology: Official Journal of the Korean Radiological Society
https://www.readbyqxmd.com/read/28092914/paraneoplastic-cerebellar-degeneration-associated-with-pelvic-liposarcoma-a-rare-case-report
#3
Liang Zhou, Xin Wei, Nian-Wei Wu, Han-Mei Zhang, Bang-Hua Liao, Shu-Lian Chen, Hong Li, Yu-Chun Zhu, Kun-Jie Wang
Paraneoplastic cerebellar degeneration (PCD) is one of the most common paraneoplastic neurological syndromes characterized by the rapid development of severe cerebellar ataxia. In this report, a 23-year-old female with noticeable dizziness and gait instability was described. The enhanced CT scanning suggested the presence of a pelvic tumor. Then, PCD was established. Postoperative pathological result defined it as a liposarcoma (LS) with dedifferentiation. Interestingly, clinical symptoms disappeared after the surgical removal of the pelvic tumor...
January 17, 2017: Urologia Internationalis
https://www.readbyqxmd.com/read/28088193/invasive-cardiac-lipoma-a-case-report-and-review-of-literature
#4
Jason D'Souza, Rajesh Shah, Aamer Abbass, Jeremy R Burt, Aditya Goud, Chanukya Dahagam
BACKGROUND: Cardiac lipomas are rare benign tumors of the heart. They are usually asymptomatic and are thus most often diagnosed on autopsies. Symptoms, when present, depend upon the location within the heart. Typical locations are the endocardium of the right atrium and the left ventricle. Diagnostic modality of choice is cardiac MRI. Treatment guidelines have not yet been established due to the very low prevalence of these tumors and are thus guided by the patient's symptomatology. CASE PRESENTATION: We describe a case of an invasive cardiac lipoma, wherein the initial symptom of the patient was shortness of breath...
January 14, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28076606/giant-gastric-lipossarcoma-case-report-and-review-of-the-literature
#5
Jacques Matone, Samuel Okazaki, Gabriel Naman Maccapani, Thiago Trolez Amancio, Renée Zon Filippi, Antonio Luiz de Vasconcellos Macedo
Liposarcoma is one of the most common soft tissue sarcomas in adults, occurring in 15 to 20% of all patients with sarcoma. Primary liposarcoma of the stomach is rare. We report a case of patient with giant gastric liposarcoma who underwent surgery after a gastrointestinal bleeding. Preoperative hystopathological diagnosis was not established, even after three biopsy attempts. We discuss differential diagnosis, genetic causes, diagnosis strategies and treatment. RESUMO O lipossarcoma é um tipo comum de sarcomas em adultos, com incidência entre 15 e 20% entre os sarcomas...
October 2016: Einstein
https://www.readbyqxmd.com/read/28074298/effect-of-intraoperative-radiotherapy-in-the-treatment-of-retroperitoneal-sarcoma
#6
Liz B Wang, David McAneny, Gerard Doherty, Teviah Sachs
BACKGROUND: Current National Comprehensive Cancer Network guidelines for the treatment of retroperitoneal sarcomas (RPS) endorse surgical resection, but the role of radiotherapy (RT) is less clear. We investigate the utilization and benefits of intraoperative RT (IORT) in the treatment of RPS. METHODS: We queried the Surveillance, Epidemiology and End Results (SEER) database (1988-2013) for the utilization of IORT and perioperative external beam RT (EBRT) in patients who underwent surgical resection of RPS...
January 10, 2017: International Journal of Clinical Oncology
https://www.readbyqxmd.com/read/28057392/primary-retroperitoneal-soft-tissue-sarcoma-imaging-appearances-pitfalls-and-diagnostic-algorithm
#7
REVIEW
C Messiou, E Moskovic, D Vanel, C Morosi, R Benchimol, D Strauss, A Miah, H Douis, W van Houdt, S Bonvalot
Although retroperitoneal sarcomas are rare tumours, they can be encountered by a wide variety of clinicians as they can be incidental findings on imaging or present with non specific symptoms and signs. Surgical resection can offer hope of cure and patient outcomes are improved when patients are managed in high-volume specialist centers. Failure to recognize retroperitoneal sarcomas on imaging can lead to inappropriate management in inexperienced centers. Therefore it is critical that a diagnosis of retroperitoneal sarcoma should be considered in the differential diagnosis of a retroperitoneal mass with prompt referral to a soft tissue sarcoma unit...
December 9, 2016: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28045549/curcumin-and-viscum-album-extract-decrease-proliferation-and-cell-viability-of-soft-tissue-sarcoma-cells-an-in-vitro-analysis-of-eight-cell-lines-using-real-time-monitoring-and-colorimetric-assays
#8
K Harati, B Behr, A Daigeler, T Hirsch, F Jacobsen, M Renner, A Harati, C Wallner, M Lehnhardt, M Becerikli
BACKGROUND: The cytostatic effects of the polyphenol curcumin and Viscum album extract (VAE) were assessed in soft-tissue sarcoma (STS) cells. METHODS: Eight human STS cell lines were used: fibrosarcoma (HT1080), liposarcoma (SW872, T778, MLS-402), synovial sarcoma (SW982, SYO1, 1273), and malignant fibrous histiocytoma (U2197). Primary human fibroblasts served as control cells. Cell proliferation, viability, and cell index (CI) were analyzed by BrdU assay, MTT assay, and real-time cell analysis (RTCA)...
January 3, 2017: Nutrition and Cancer
https://www.readbyqxmd.com/read/28044001/resection-of-giant-mediastinal-liposarcoma-via-%C3%A2-shape-incision
#9
Wei Huang, Ge Ning Jiang
Primary mediastinal liposarcomas are extremely rare conditions often resected through standard median sternotomy or lateral thoracotomy. However, the management of a very huge mediastinal tumor involving hemithorax through these two common surgical approaches is always challenging. Herein, we report a case of applying median sternotomy with a sternum transection plus a right fourth intercostal thoracotomy ('⊣ shape' incision) to resect a giant primary anterior mediastinal liposarcoma extending into the whole right thorax...
January 2, 2017: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/28036291/assessing-the-clinical-value-of-micrornas-in-formalin-fixed-paraffin-embedded-liposarcoma-tissues-overexpressed-mir-155-is-an-indicator-of-poor-prognosis
#10
Nikolaos Kapodistrias, Konstantinos Mavridis, Anna Batistatou, Penelope Gogou, Vasilios Karavasilis, Ioannis Sainis, Evangelos Briasoulis, Andreas Scorilas
Liposarcoma (LPS) is a malignancy with extreme heterogeneity and thus optimization towards personalizing patient prognosis and treatment is essential. Here, we evaluated miR-155, miR-21, miR-143, miR-145 and miR-451 that are implicated in LPS, as novel FFPE tissue biomarkers.A total of 83 FFPE tissue specimens from primary LPS and lipomas (LPM) were analyzed. A proteinase K incubation-Trizol treatment coupled protocol was used for RNA isolation. After polyadenylation of total RNA and reverse transcription, expression analysis of 9 candidate reference and 5 target miRNAs was performed by qPCR...
December 28, 2016: Oncotarget
https://www.readbyqxmd.com/read/28035254/esophageal-liposarcoma-well-differentiated-rhabdomyomatous-type
#11
Hisham M Valiuddin, Arianna Barbetta, Benedetto Mungo, Elizabeth A Montgomery, Daniela Molena
Rhabdomyomatous well-differentiated esophageal liposarcomas are extremely rare. As of August 2016, only one other such case has been reported in the English-language medical literature. Liposarcomas in general are one of the most common soft tissue neoplasms in adults, but the incidence of primary esophageal liposarcomas is exceptionally low. There have been only 42 reported cases of primary liposarcoma of the esophagus worldwide thus far. These malignancies are harbored within giant fibrovascular polyps, which slowly grow within the esophageal lumen causing obstructing symptoms...
December 15, 2016: World Journal of Gastrointestinal Oncology
https://www.readbyqxmd.com/read/28018076/myxoid-liposarcoma-of-the-hand-a-rare-entity
#12
Mourad Zaraa, Khalil Haboubi, Emir Bessalah, Mohamed Ali Kedous, Mondher Mbarek
Hand liposarcomas are not well recognized in common practice, which leads to erroneous diagnostics and delayed proper treatment. We reported a case of a myxoid liposarcoma classified as stage IIb, and developed in the palmar side of the left hand in a 38-year-old man. There was an initial tumor reduction by a sclerosing agent injection that proved to be a failure. An open excisional biopsy confirmed the diagnostic after pathology examination. Recurrence occurred after 2 years, followed by a second resection and an adjunctive radiotherapy...
October 2016: Journal of Clinical Orthopaedics and Trauma
https://www.readbyqxmd.com/read/28012446/retroperitoneal-liposarcoma-excreting-insulin-like-growth-factor-2-that-induced-severe-hypoglycemia
#13
Takuma Kato, Mikio Sugimoto, Motoki Yamashita, Yasuyuki Miyauchi, Hiromi Hirama, Hiroyuki Tsunemori, Nobufumi Ueda, Hitomi Imachi, Shinsuke Shibuya, Yoshio Kushida, Yoshiyuki Kakehi
Insulin-like growth factor 2 is overexpressed in various cancers, and is associated with a poor prognosis. Also, it is known that insulin-like growth factor 2 is an etiology of non-islet cell tumor hypoglycemia. In this report, we describe a case of unexpected hypoglycemia caused by a dedifferentiated liposarcoma producing insulin-like growth factor 2. A large mass in the retroperitoneum was detected in a 61-year-old man who complained of appetite loss. Despite having no history of diabetes mellitus, hypoglycemia suddenly occurred after admission, but oral glucose therapy was ineffective...
December 24, 2016: International Journal of Urology: Official Journal of the Japanese Urological Association
https://www.readbyqxmd.com/read/27995856/spermatic-cord-dedifferentiated-liposarcoma-presenting-as-a-recurrent-inguinal-hernia
#14
Chad Crigger, John Barnard, Stanley Zaslau, Jeffrey A Vos
Paratesticular sarcomas are a rare entity and provide a unique clinical challenge due to their slow growing, often painless natural course. Adding to this challenge is the complex anatomy of the scrotum that allows these masses to mimic other conditions, including inguinal hernia, cysts, or fluid collections. We report such a case and our approach to an 83-year-old male with dedifferentiated liposarcoma of the spermatic cord with a history of inguinal hernia. In doing so, we highlight the need for thorough evaluation of scrotal masses and the management of these rare, though well-described, tumors...
December 2016: Canadian Journal of Urology
https://www.readbyqxmd.com/read/27994926/intraarticular-giant-size-angiolipoma-of-the-knee-causing-lateral-patellar-dislocation
#15
Gökhan İlyas, Ali Turgut, Duygu Ayaz, Önder Kalenderer
BACKGROUND: Angiolipomas are benign tumors usually seen in patients during their 2(nd) and 3(rd) decades. The subcutaneous region of the trunk, neck and extremities are the places where they generally settle. There is only one case report on angiolipoma in the knee joint that was resected by arthroscopic procedure in the English literature. CASE REPORT: We present a case of a giant-size multilobular non-infiltrating angiolipoma, extending outside of the right knee joint and causing lateral patellar dislocation in a thirteen-year-old boy...
November 2016: Balkan Medical Journal
https://www.readbyqxmd.com/read/27975026/combined-use-of-an-anterolateral-thigh-flap-and-superficial-inferior-epigastric-artery-flap-for-reconstruction-of-an-extensive-abdominal-wall-defect
#16
Shimpei Miyamoto, Yu Kagaya, Masaki Arikawa, Eisuke Kobayashi
Reconstruction of large abdominal wall defects is challenging. We herein report the successful reconstruction of an extensive abdominal wall defect using a novel combination of flaps after sarcoma resection. A 74-year-old man presented with a dedifferentiated liposarcoma on his abdominal wall. He underwent excision of the tumor, which resulted in an extensive abdominal wall defect. The defect was reconstructed with a pedicled anterolateral thigh flap with an iliotibial tract and a pedicled superficial inferior epigastric artery flap...
November 2016: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/27942382/a-case-report-giant-intra-abdominal-liposarcoma-presenting-acute-renal-failure
#17
Kazim Duman, Mustafa Girgin, Gokhan Artas
INTRODUCTION: Liposarcomas represent 20-30% of adult soft tissue tumors and its abdominal localization occurs only in 5% of cases. Most are asymptomatic, but few present with abdominal mass and pain, fatigue, nausea, vomiting. They infiltrate adjacent organs and cause intestinal obstruction, intestinal ischemia-perforation, hydronephrosis, ureteric fistula and even aortic rupture. Here we aimed to report a rare case of a giant liposarcoma which originated from mesentery. PRESENTATION OF CASE: A 45-year-old male presented with slightly abdomen distention, urinary retention, oliguria since fifteen days...
December 2016: Annals of Medicine and Surgery
https://www.readbyqxmd.com/read/27939834/focus-on-the-role-of-caveolin-and-cavin-protein-families-in-liposarcoma
#18
REVIEW
Silvia Codenotti, Marika Vezzoli, Eugenio Monti, Alessandro Fanzani
The identification of ancillary biomarkers useful to improve diagnosis is a major challenge for adipocytic liposarcoma (LPS), the most common type among soft tissue sarcomas affecting adulthood. Recent findings have reported the expression of some proteins belonging to Caveolin and Cavin families as a critical hallmark distinctive of the least aggressive, well-differentiated LPS tumors. These proteins are involved in the biogenesis, morphology and function of caveolae, minute bulb-shaped domains of the plasma membrane that play a crucial role in the adipose tissue by controlling hormone-dependent uptake of nutrients and contributing to the maintenance of tissue integrity...
December 7, 2016: Differentiation; Research in Biological Diversity
https://www.readbyqxmd.com/read/27932168/spindle-cell-lipoma-in-an-end-stage-renal-allograft-case-report
#19
Z Zhao, S Selvarajan, A L S Tiong, T H Lim, L Y Khor
BACKGROUND: Spindle cell lipoma is an uncommon variant of lipoma and usually occurs as a solitary, subcutaneous, and well circumscribed lesion in the posterior neck, shoulders, and back of older men. Primary renal lipomas are rarely reported. Spindle cell lipoma in the kidney has not been previously described in the literature. CASE REPORT: A 60-year-old Chinese man suffered graft failure 10 years after living related donor kidney transplantation. During cancer surveillance, he was found to have a mass in the renal allograft, which increased in size and was suspicious for renal cell carcinoma on computerized tomographic scan...
November 2016: Transplantation Proceedings
https://www.readbyqxmd.com/read/27929599/surgical-management-of-parapharyngeal-space-tumors-the-role-of-cervical-and-lateral-skull-base-approaches
#20
Arturo Mario Poletti, Siba P Dubey, Giovanni Colombo, Giovanni Cugini
We conducted a retrospective study to analyze the role of the cervical and lateral skull base approaches in the surgical excision of parapharyngeal space (PPS) tumors. Our study population was made up of 34 patients-15 males and 19 females, aged 13 to 73 years (mean: 50.6)-who had presented to us with a PPS tumor during a 9-year period. The 34 cases included 23 benign tumors and 11 malignancies. The 23 benign tumors consisted of 11 pleomorphic adenomas, 5 schwannomas, 2 paragangliomas, 2 Warthin tumors, 1 oncocytoma, 1 hamartoma, and 1 osteochondroma...
December 2016: Ear, Nose, & Throat Journal
keyword
keyword
7658
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"