Rong-Xin Song, Hui-Tao Miao, Shi-Yan Jia, Wen-Guang Li, Ji-Zhen Liu, Wei Zhang, Bao-Rui Xing, Jian-Yong Zhao, Li-Min Zhang, Xiao-Ming Li
Peri-operative hemorrhagic shock and resuscitation (HSR), a severe traumatic stress, is closely associated with post-operative anxiety, depression, and cognitive dysfunction, subsequently causing a serious burden on families and society. Following the co-release of corticotropin-releasing factor and catecholamine, traumatic stress activates dopaminergic neurons, increasing the addictive behavior and neurocognitive impairment risks. This study investigates the association between cognitive dysfunction and dopaminergic neurons in the mPFC under HSR conditions...
December 2, 2023: Molecular Neurobiology