keyword
https://read.qxmd.com/read/38469757/microbeads-as-carriers-for-bacillus-pumilus-a-biofertilizer-focus-on-auxin-production
#1
JOURNAL ARTICLE
Solange V Benítez, Rocio Carrasco, Juan D Giraldo, Mauricio Schoebitz
The study aimed to develop a solid biofertilizer using Bacillus pumilus , focusing on auxin production to enhance plant drought tolerance. Methods involved immobilising B. pumilus in alginate-starch beads, focusing on microbial concentration, biopolymer types, and environmental conditions. The optimal formulation showed a diameter of 3.58 mm ± 0.18, a uniform size distribution after 15 h of drying at 30 °C, a stable bacterial concentration (1.99 × 109 CFU g-1 ± 1...
March 12, 2024: Journal of Microencapsulation
https://read.qxmd.com/read/38462848/preparation-of-layer-assembled-w-o-w-type-microencapsulated-beads-and-application-in-solid-state-fermentation
#2
JOURNAL ARTICLE
Lei Wen, Jingrong Jiang, Jia Zheng, Hong Wang, Min Huang, Xuyan Zong, Li Li
In this study, microcapsule beads-0-3-layers (M-0-3 indicates microencapsulated beads with 0, 1, 2, and 3 layers) were prepared, their properties were measured and characterized, and the effects of M-0-3 on solid-state fermentation were investigated. The results showed that in a liquid environment, the releasing glucoamylase activities of M-0-3 were 55.77%, 47.67%, 45.85%, and 42.87% in 360 h, respectively. In the solid environment, the reducing sugar production efficiency of M-0-3 was 29.84%, 27.72%, 19...
March 10, 2024: Journal of Food Science
https://read.qxmd.com/read/38456667/ethosomes-a-potential-nanovesicular-carrier-to-enhancing-the-drug-delivery-against-skin-barriers
#3
REVIEW
Huma Hameed, Saleha Faheem, Mahtab Ahmad Khan, Anam Hameed, Nelofer Ereej, Hafsa Ihsan
Ethosomes, which are liposomes like structures, mainly composed primarily of ethanol, have attracted considerable attention due to their potential to enhance the drug permeation via skin. The article discusses the formulation and preparation methods of ethosomes, offering insights into the various factors that influence their size, shape, and stability. Moreover, it explores the techniques used to assess the physicochemical properties of ethosomes and their impact on drug delivery effectiveness. The article also elucidates the mechanism by which ethosomes enhance skin permeation, emphasising their ability to modify the lipid structure and fluidity of the stratum corneum...
March 8, 2024: Journal of Microencapsulation
https://read.qxmd.com/read/38453505/lethal-toxin-neutralizing-antibody-response-induced-following-oral-vaccination-with-a-microencapsulated-bacillus-anthracis-sterne-strain-34f2-vaccine-proof-of-concept-study-in-white-tailed-deer-odocoileus-virginianus
#4
JOURNAL ARTICLE
Jamie S Benn, Chase M Nunez, Alice Blue-McLendon, Sankar P Chaki, Thomas A Ficht, Allison C Rice-Ficht, Walter E Cook
Improved methods are needed to prevent wildlife deaths from anthrax. Caused by Bacillus anthracis , naturally occurring outbreaks of anthrax are frequent but unpredictable. The commercially available veterinary vaccine is labeled for subcutaneous injection and is impractical for large-scale wildlife vaccination programs; therefore, oral vaccination is the most realistic method to control and prevent these outbreaks. We reported the induction of an anthrax-specific lethal toxin (LeTx) neutralizing antibody response in mice following oral vaccination with alginate microcapsules containing B...
March 2024: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://read.qxmd.com/read/38451031/construction-of-various-lipid-carriers-to-study-the-transdermal-penetration-mechanism-of-sinomenine-hydrochloride
#5
JOURNAL ARTICLE
Mengyao Cui, Yaqing Li, Jing Li, Nini Jia, Wenxuan Cao, Zhengguang Li, Xiang Li, Xiaoqin Chu
OBJECTIVE: To investigate the transdermal mechanisms and compare the differences in transdermal delivery of Sinomenine hydrochloride (SN) between solid lipid nanoparticles (SLN), liposomes (LS), and nanoemulsions (NE). METHODS: SN-SLN, SN-LS and SN-NE were prepared by ultrasound, ethanol injection and spontaneous emulsification, respectively. FTIR, DSC, in vitro skin penetration, activation energy (Ea) analysis were used to explore the mechanism of drug penetration across the skin...
March 7, 2024: Journal of Microencapsulation
https://read.qxmd.com/read/38411308/development-of-microencapsulated-grape-juice-powders-using-black-isabel-grape-peel-pectin-and-application-in-jelly-formulation-with-enhanced-in-vitro-bioaccessibility-of-anthocyanins
#6
JOURNAL ARTICLE
Ayse Karadag, Kubra Ozkan, Osman Sagdic
In this study, pigmented pectin (grape pectin, GP) was extracted from the peels of black Isabel grapes. This highly methoxylated GP was composed mainly of galacturonic acid, arabinose, and other neutral monosaccharides. Its red color was ascribed to the anthocyanin content, and the main contribution was from malvidin-3-O-glucoside. To improve the yield and color properties of spray-dried Isabel grape juice powders, maltodextrin (MD) was substituted with this colored GP. When 25% of MD was substituted with GP, the powder yield increased from 46...
February 27, 2024: Journal of Food Science
https://read.qxmd.com/read/38410930/astaxanthin-loaded-alginate-chitosan-gel-beads-activate-nrf2-and-pro-apoptotic-signalling-pathways-against-oxidative-stress
#7
JOURNAL ARTICLE
Hamieh Goshtasbi, Elaheh Dalir Abdolahinia, Marziyeh Fathi, Ali Movafeghi, Hossein Omidian, Jaleh Barar, Yadollah Omidi
Oxidative stress (OS) plays a crucial role in disease development. Astaxanthin (ATX), a valuable natural compound, may reduce OS and serve as a treatment for diseases like neurodegenerative disorders and cancer. Nuclear factor-erythroid 2-related factor 2 (Nrf2) regulates antioxidant enzymes and OS management. We evaluated ATX's antioxidant activity via Alg-CS/ATX gel beads in vitro. ATX-encapsulated alginate-chitosan (Alg-CS/ATX) gel beads were synthesized and structurally/morphologically characterized by SEM, FT-IR, and XRD...
February 27, 2024: Journal of Microencapsulation
https://read.qxmd.com/read/38410926/enhanced-in-vitro-and-ex-vivo-transdermal-permeation-of-microemulsion-gel-of-tapentadol-hydrochloride
#8
JOURNAL ARTICLE
Nimmathota Madhavi, Heera Battu
Aim of the current study is to develop a microemulsion gel for transdermal delivery of tapentadol hydrochloride. Microemulsion was developed using phase diagram and subjected to assay, globule size, PDI, zeta potential, TEM and in vitro drug release studies. The optimized microemulsion was converted into gel using carbopol 934 NF and evaluated for viscosity, spreadability, in vitro , ex vivo , FTIR, DSC, stability and skin irritation studies. The mean globule size, PDI, zeta potential and in vitro drug release of microemulsion were found 247...
February 27, 2024: Journal of Microencapsulation
https://read.qxmd.com/read/38410890/gelatine-nanoparticles-encapsulating-three-edible-plant-extracts-as-potential-nanonutraceutical-agents-against-type-2-diabetes-mellitus
#9
JOURNAL ARTICLE
Akurange Sujeevi Dammadinna Wickramasinghe, Anoja Priyadarshani Attanayake, Pabasara Kalansuriya
AIM: To optimise, and characterise gelatine nanoparticles (GNPs) encapsulating plant extracts and evaluate the glucose-lowering potential. METHODS: GNPs encapsulating plant extracts were prepared by desolvation method followed by adsorption. The GNPs were characterised by loading efficiency, loading capacity, particle size, zeta potential, SEM and FTIR. The glucose-lowering activity of GNPs was determined using oral glucose tolerance test in high-fat diet fed streptozotocin-induced Wistar rats...
February 27, 2024: Journal of Microencapsulation
https://read.qxmd.com/read/38410267/soymilk-stability-increase-using-polyphenols-microcapsules
#10
JOURNAL ARTICLE
Mariana Larrauri, Claudia M Asensio, María P Martín, Patricia R Quiroga, Nelson R Grosso, Valeria Nepote
Functional beverages have aroused a great interest to the food industry. Among the functional ingredients, there is a growing demand for antioxidant incorporation into foods, which implies a challenge to preserve their bioactivity. The health benefits provided by soymilk can be improved by the addition with microcapsules of polyphenols from peanut skin and this procedure is an alternative to protect these natural and bioactive compounds from environmental factors. The aim of this work was to determine the chemical, antioxidant, microbiological and sensory changes during storage of the product...
April 2024: Journal of Food Science and Technology
https://read.qxmd.com/read/38408709/miniaturized-screening-and-performance-prediction-of-tailored-subcutaneous-extended-release-formulations-for-preclinical-in-vivo-studies
#11
JOURNAL ARTICLE
Marco Block, Peter Sieger, Cornelius Truenkle, Christoph Saal, Roman Simon, Ines Truebenbach
Microencapsulation of active pharmaceutical ingredients (APIs) for preparation of long acting injectable (LAI) formulations is an auspicious technique to enable preclinical characterization of a broad variety of APIs, ideally independent of their physicochemical and pharmacokinetic (PK) characteristics. During early API discovery, tunable LAI formulations may enable pharmacological proof-of-concept for the given variety of candidates by tailoring the level of plasma exposure over the duration of various timespans...
February 24, 2024: European Journal of Pharmaceutical Sciences
https://read.qxmd.com/read/38403207/conception-of-ph-sensitive-calcium-alginate-poly-vinyl-alcohol-hydrogel-beads-for-controlled-oral-curcumin-delivery-systems-antibacterial-and-antioxidant-properties
#12
JOURNAL ARTICLE
Zineb Touzout, Naima Abdellaoui, Assia Siham Hadj-Hamou
Curcumin, a bioactive compound derived from the rhizome of Curcuma longa, has gained widespread attention for its potential therapeutic properties, including anti-inflammatory, antioxidant and anticancer effects. However, its poor aqueous solubility, instability and limited bioavailability have hindered its clinical applications. New beads formulations based on sodium alginate biopolymer (SA) and poly vinyl alcohol (PVA) were successfully prepared and evaluated as a potential drug vehicle for extended release of curcumin (Cur)...
February 23, 2024: International Journal of Biological Macromolecules
https://read.qxmd.com/read/38389966/characteristics-of-lactobacillus-casei-probiotic-microparticles-in-l-type-methacrylic-acid-copolymer-matrix
#13
JOURNAL ARTICLE
Sugiyartono, Widji Soeratri, Arini Permatasari, Ayun Dewi Rahayu, Dwi Setyawan, Dewi Isadiartuti
Lactobacillus casei (LC) is a type of lactic acid bacterium that is known for its beneficial probiotic properties. However, it is not typically found in the human intestine because it lacks acid resistance. LC thrives in an optimal pH environment of 6.8 and can be initiated in a more acidic environment at a pH of 3.5. This study purposed to compare the effect of L-type methacrylic acid copolymer (MAC) as a matrix (0.50%, 0.75%, and 1.00%) on the physical characteristics of LC probiotic microparticles made by the spray drying process...
2024: Journal of Advanced Pharmaceutical Technology & Research
https://read.qxmd.com/read/38387628/development-of-chitosan-carrageenan-macrobeads-for-encapsulation-of-paenibacillus-polymyxa-and-its-biocontrol-efficiency-against-clubroot-disease-in-brassica-crops
#14
JOURNAL ARTICLE
Huajun Kang, Tengfei Fan, Zihan Lin, Yanxia Shi, Xuewen Xie, Lei Li, Sheng Xiang, Xiaowei Yuan, Xingsheng Li, Baoju Li, Ali Chai
Clubroot, caused by the obligate parasite Plasmodiophora brassicae, is one of the most important diseases of brassicas. The antagonistic bacterium Paenibacillus polymyxa ZF129 can suppress clubroot while its effectiveness is often unstable. To control clubroot more effectively, the macrobeads for controlled release of ZF129 were prepared using microencapsulation technology. Macrobeads with various ratios of chitosan (2 % w/w): carrageenan (0.3 % w/v) were prepared by an ionotropic gelation method and the bacteria ZF129 was loaded into macrobeads...
February 20, 2024: International Journal of Biological Macromolecules
https://read.qxmd.com/read/38367575/a-unified-thermodynamic-and-kinetic-approach-for-prediction-of-microcapsule-morphologies
#15
JOURNAL ARTICLE
Viktor Eriksson, Sofia Edegran, Matilda Croy, Lars Evenäs, Markus Andersson Trojer
HYPOTHESIS: Microcapsule formation, following internal phase separation by solvent evaporation, is controlled by two main factors of thermodynamic and kinetic origin. Morphology prediction has previously focused on the final thermodynamical state in terms of spreading conditions, limiting the prediction accuracy. By additionally considering kinetic effects as the emulsion droplet evolves through the two-phase region of its ternary phase diagram during solvent evaporation, this should enhance prediction accuracy and explain a wider range of morphologies...
January 28, 2024: Journal of Colloid and Interface Science
https://read.qxmd.com/read/38345078/spray-dried-acerola-malpighia-emarginata-dc-juice-particles-to-produce-phytochemical-rich-starch-based-edible-films
#16
JOURNAL ARTICLE
Dayene Nunes Ribeiro, Kátia Cristina Borges, Kátia Nicolau Matsui, Roberta Targino Hoskin
This study aimed to produce spray dried acerola juice microparticles with different protein carriers to be incorporated into edible starch films. The microparticles were evaluated for solids recovery, polyphenol retention, solubility, hygroscopicity, particle size distribution, X-ray diffraction, phytochemical compounds and antioxidant activity. Acerola microparticles produced with WPI/hydrolysed collagen carriers (AWC) with higher solids recovery (53.5 ± 0.34% w/w), polyphenol retention (74...
February 12, 2024: Journal of Microencapsulation
https://read.qxmd.com/read/38340314/an-optimized-chitosan-alginate-based-microencapsulation-of-lime-peel-essential-oil-and-its-application-as-an-antibacterial-textile
#17
JOURNAL ARTICLE
Nastiti Nur Indriyani, Jamaludin Al-Anshori, Tatang Wahyudi, Mohamad Nurzaman, Sarifah Nurjanah, Nandang Permadi, Euis Julaeha
A functional textile immobilized by microcapsules of the lime peel essential oils of C. aurantifolia (LPEO) was prepared and characterized. A varied amount of Chitosan/Alginate (CH/AG) ratios, followed by a mass of LPEO and concentration of sodium tripolyphosphate (STPP) crosslinker, was optimized sequentially to coacervate LPEO using a Tween 80 emulsifier. An antibacterial assay against both Gram-positive and Gram-negative bacteria was further evaluated for the embedded microcapsules. The LPEO (0.2 g) was effectively coacervated by CH/AG (5:3) crosslinked by 2% of STTP to give a yield, oil content (OC), and encapsulation efficiency (EE) of 53...
February 10, 2024: Journal of Biomaterials Science. Polymer Edition
https://read.qxmd.com/read/38327854/modulating-of-microencapsulated-virgin-coconut-oil-based-creamer
#18
JOURNAL ARTICLE
Nameer Khairullah Mohammed, Nurul Hawa Ahmad, Belal J Muhialdin, Anis Shobirin Meor Hussin
This work aims to produce a virgin coconut oil (VCO) creamer through two drying stages; spray drying followed by fluidised bed drying, and to examine its antioxidant properties and oxidative stability during different storage conditions. Evaluation of the physicochemical properties of spray dry VCO and oxidative stability of the VCO creamer were performed using peroxide value (PV), antioxidant activity (DPPH), and total phenolic content (TPC) at 25, 4, and 25 °C, respectively, for 8 weeks. Agglomeration process has improved the agglomerated VCO creamer's properties in terms of moisture content (4...
March 2024: Journal of Food Science and Technology
https://read.qxmd.com/read/38323407/microencapsulation-as-a-protective-strategy-for-sialylated-immunoglobulin-g-efficacy-in-alleviating-symptoms-of-dextran-sulfate-sodium-induced-colitis-in-mice-and-potential-mechanisms
#19
JOURNAL ARTICLE
Chunxu Chen, Jiaming Xu, Tianxiang Han, Guijie Chen, Kun Yu, Chuanlai Du, Wenbiao Shen, Yi Sun, Xiaoxiong Zeng
Sialylated immunoglobulin G (IgG) is a vital glycoprotein in breast milk with the ability to promote the growth of Bifidobacterium in gut microbiota and relieve inflammatory bowel disease (IBD) symptoms in vitro . Here, it was found that the microcapsules with sialylated IgG could protect and release sialylated IgG with its structure and function in the intestine. Furthermore, the sialylated IgG microcapsules alleviated the clinical symptoms (body weight, feed quantity, and colon length loss), decreased disease activity index score, suppressed the production of pro-inflammatory cytokines (TNF-α, IL-6, IL-1β, IFN-γ, and MCP-1) and endotoxin (lipopolysaccharide), and enhanced the intestinal mucosal barrier (Claudin1, Muc2, Occludin, and ZO-1) in dextran sulfate sodium (DSS)-induced colitis mice...
February 7, 2024: Journal of Agricultural and Food Chemistry
https://read.qxmd.com/read/38320637/advances-in-the-construction-and-application-of-konjac-glucomannan-based-delivery-systems
#20
REVIEW
Yanting Zhang, Cailing Tong, Yuanyuan Chen, Xiaolu Xia, Shizhong Jiang, Chao Qiu, Jie Pang
Konjac glucomannan (KGM) has been widely used to deliver bioactive components due to its naturalness, non-toxicity, excellent biodegradability, biocompatibility, and other characteristics. This review presents an overview of konjac glucomannan as a matrix, and the types of konjac glucomannan-based delivery systems (such as hydrogels, food packaging films, microencapsulation, emulsions, nanomicelles) and their construction methods are introduced in detail. Furthermore, taking polyphenol compounds, probiotics, flavor substances, fatty acids, and other components as representatives, the applied research progress of konjac glucomannan-based delivery systems in food are summarized...
February 4, 2024: International Journal of Biological Macromolecules
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