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journal of microencapsulation

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https://www.readbyqxmd.com/read/14971250/local-anti-infective-therapy-pharmacological-agents-a-systematic-review
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REVIEW
Philip J Hanes, James P Purvis
BACKGROUND: It is well recognized that periodontal diseases are bacterial in nature. An essential component of therapy is to eliminate or control these pathogens. This has been traditionally accomplished through mechanical means (scaling and root planing [SRP]), which is time-consuming, difficult, and sometimes ineffective. Over the past 20 years, locally delivered, anti-infective pharmacological agents, most recently employing sustained-release vehicles, have been introduced to achieve this goal...
December 2003: Annals of Periodontology
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