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https://www.readbyqxmd.com/read/28269283/kernel-temporal-enhancement-approach-for-loreta-source-reconstruction-using-eeg-data
#1
Cristian A Torres-Valencia, M Claudia Joana Santamaria, Mauricio A Alvarez
Reconstruction of brain sources from magnetoencephalography and electroencephalography (M/EEG) data is a well known problem in the neuroengineering field. A inverse problem should be solved and several methods have been proposed. Low Resolution Electromagnetic Tomography (LORETA) and the different variations proposed as standardized LORETA (sLORETA) and the standardized weighted LORETA (swLORETA) have solved the inverse problem following a non-parametric approach, that is by setting dipoles in the whole brain domain in order to estimate the dipole positions from the M/EEG data and assuming some spatial priors...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28260198/neurons-internalize-functionalized-micron-sized-silicon-dioxide-microspheres
#2
Veronica J Wallace, Raffaello Cimbro, F Javier Rubio, Lowella V Fortuno, Julie C Necarsulmer, Pyry P Koivula, Mark J Henderson, Lindsay M DeBiase, Brandon L Warren, Brandon K Harvey, Bruce T Hope
Microparticles have potential as neuron-specific delivery platforms and devices with many applications in neuroscience, pharmacology, and biomedicine. To date, most literature suggests that neurons are not phagocytic cells capable of internalizing microparticles larger than 0.5 μm. We report that neurons transport fluorescently labeled silica microspheres with diameters of 1-2 μm into neurons in vitro and in rat brain without having overt effects on cell viability. Using flow cytometry, fluorescence-activated cell sorting, and confocal and electron microscopy, we first found that SH-SY5Y human neuroblastoma cells internalized 1-μm silicon microspheres with surface charges of -70 mV (hydroxyl and carboxyl), -30 mV (amino), and +40 mV (ammonio)...
March 4, 2017: Cellular and Molecular Neurobiology
https://www.readbyqxmd.com/read/28227519/kernel-temporal-enhancement-approach-for-loreta-source-reconstruction-using-eeg-data
#3
Cristian A Torres-Valencia, M Claudia Joana Santamaria, Mauricio A Alvarez, Cristian A Torres-Valencia, M Claudia Joana Santamaria, Mauricio A Alvarez, Mauricio A Alvarez, Cristian A Torres-Valencia
Reconstruction of brain sources from magnetoencephalography and electroencephalography (M/EEG) data is a well known problem in the neuroengineering field. A inverse problem should be solved and several methods have been proposed. Low Resolution Electromagnetic Tomography (LORETA) and the different variations proposed as standardized LORETA (sLORETA) and the standardized weighted LORETA (swLORETA) have solved the inverse problem following a non-parametric approach, that is by setting dipoles in the whole brain domain in order to estimate the dipole positions from the M/EEG data and assuming some spatial priors...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28162776/the-future-of-psychiatry-brain-devices
#4
Jorge Alberto Costa E Silva, Ricardo Ewbank Steffen
Recent advances in deep brain stimulators and brain-machine interfaces have greatly expanded the possibilities of neuroprosthetics and neuromodulation. Together with advances in neuroengineering, nanotechnology, molecular biology and material sciences, it is now possible to address fundamental questions in neuroscience in new, more powerful ways. It is now possible to apply these new technologies in ways that range from augmenting and restoring function to neuromodulation modalities that treat neuropsychiatric disorders...
April 2017: Metabolism: Clinical and Experimental
https://www.readbyqxmd.com/read/28003656/closed-loop-brain-training-the-science-of-neurofeedback
#5
REVIEW
Ranganatha Sitaram, Tomas Ros, Luke Stoeckel, Sven Haller, Frank Scharnowski, Jarrod Lewis-Peacock, Nikolaus Weiskopf, Maria Laura Blefari, Mohit Rana, Ethan Oblak, Niels Birbaumer, James Sulzer
Neurofeedback is a psychophysiological procedure in which online feedback of neural activation is provided to the participant for the purpose of self-regulation. Learning control over specific neural substrates has been shown to change specific behaviours. As a progenitor of brain-machine interfaces, neurofeedback has provided a novel way to investigate brain function and neuroplasticity. In this Review, we examine the mechanisms underlying neurofeedback, which have started to be uncovered. We also discuss how neurofeedback is being used in novel experimental and clinical paradigms from a multidisciplinary perspective, encompassing neuroscientific, neuroengineering and learning-science viewpoints...
February 2017: Nature Reviews. Neuroscience
https://www.readbyqxmd.com/read/27794362/robotic-quantification-of-upper-extremity-loss-of-independent-joint-control-or-flexion-synergy-in-individuals-with-hemiparetic-stroke-a-review-of-paradigms-addressing-the-effects-of-shoulder-abduction-loading
#6
REVIEW
Michael D Ellis, Yiyun Lan, Jun Yao, Julius P A Dewald
Unsupported or "against-gravity" reaching and hand opening movements are greatly impaired in individuals with hemiparetic stroke. The reduction in reaching excursion and hand opening is thought to be primarily limited by abnormal muscle co-activation of shoulder abductors with distal limb flexors, known as flexion synergy, that results in a loss of independent joint control or joint individuation. Our laboratory employs several methods for quantifying this movement impairment, however the most documented techniques are sophisticated and laboratory-based...
October 29, 2016: Journal of Neuroengineering and Rehabilitation
https://www.readbyqxmd.com/read/27727219/recent-patents-in-neurotechnology-and-neuroengineering
#7
(no author information available yet)
No abstract text is available yet for this article.
October 11, 2016: Nature Biotechnology
https://www.readbyqxmd.com/read/27721741/trends-and-challenges-in-neuroengineering-toward-intelligent-neuroprostheses-through-brain-brain-inspired-systems-communication
#8
Stefano Vassanelli, Mufti Mahmud
Future technologies aiming at restoring and enhancing organs function will intimately rely on near-physiological and energy-efficient communication between living and artificial biomimetic systems. Interfacing brain-inspired devices with the real brain is at the forefront of such emerging field, with the term "neurobiohybrids" indicating all those systems where such interaction is established. We argue that achieving a "high-level" communication and functional synergy between natural and artificial neuronal networks in vivo, will allow the development of a heterogeneous world of neurobiohybrids, which will include "living robots" but will also embrace "intelligent" neuroprostheses for augmentation of brain function...
2016: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/27634714/the-effects-of-closed-loop-medical-devices-on-the-autonomy-and-accountability-of-persons-and-systems
#9
Philipp Kellmeyer, Thomas Cochrane, Oliver Müller, Christine Mitchell, Tonio Ball, Joseph J Fins, Nikola Biller-Andorno
Closed-loop medical devices such as brain-computer interfaces are an emerging and rapidly advancing neurotechnology. The target patients for brain-computer interfaces (BCIs) are often severely paralyzed, and thus particularly vulnerable in terms of personal autonomy, decisionmaking capacity, and agency. Here we analyze the effects of closed-loop medical devices on the autonomy and accountability of both persons (as patients or research participants) and neurotechnological closed-loop medical systems. We show that although BCIs can strengthen patient autonomy by preserving or restoring communicative abilities and/or motor control, closed-loop devices may also create challenges for moral and legal accountability...
October 2016: Cambridge Quarterly of Healthcare Ethics: CQ: the International Journal of Healthcare Ethics Committees
https://www.readbyqxmd.com/read/27519275/neuroprosthetics-in-amputee-and-brain-injury-rehabilitation
#10
REVIEW
Blessen C Eapen, Douglas P Murphy, David X Cifu
The goals of rehabilitation medicine programs are to promote health, restore functional impairments and improve quality of life. The field of neuroprosthetics has evolved over the last decade given an improved understanding of neuroscience and the incorporation of advanced biotechnology and neuroengineering in the rehabilitation setting to develop adaptable applications to help facilitate recovery for individuals with amputations and brain injury. These applications may include a simple cognitive prosthetics aid for impaired memory in brain-injured individuals to myoelectric prosthetics arms with artificial proprioceptive feedback for those with upper extremity amputations...
January 2017: Experimental Neurology
https://www.readbyqxmd.com/read/27445660/fascicular-topography-of-the-human-median-nerve-for-neuroprosthetic-surgery
#11
Ignacio Delgado-Martínez, Jordi Badia, Arán Pascual-Font, Alfonso Rodríguez-Baeza, Xavier Navarro
One of the most sought-after applications of neuroengineering is the communication between the arm and an artificial prosthetic device for the replacement of an amputated hand or the treatment of peripheral nerve injuries. For that, an electrode is placed around or inside the median nerve to serve as interface for recording and stimulation of nerve signals coming from the fascicles that innervate the muscles responsible for hand movements. Due to the lack of a standard procedure, the electrode implantation by the surgeon is strongly based on intuition, which may result in poor performance of the neuroprosthesis because of the suboptimal location of the neural interface...
2016: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/27377299/the-use-of-intracranial-recordings-to-decode-human-language-challenges-and-opportunities
#12
Stephanie Martin, José Del R Millán, Robert T Knight, Brian N Pasley
Decoding speech from intracranial recordings serves two main purposes: understanding the neural correlates of speech processing and decoding speech features for targeting speech neuroprosthetic devices. Intracranial recordings have high spatial and temporal resolution, and thus offer a unique opportunity to investigate and decode the electrophysiological dynamics underlying speech processing. In this review article, we describe current approaches to decoding different features of speech perception and production - such as spectrotemporal, phonetic, phonotactic, semantic, and articulatory components - using intracranial recordings...
July 1, 2016: Brain and Language
https://www.readbyqxmd.com/read/27099182/brief-wide-field-photostimuli-evoke-and-modulate-oscillatory-reverberating-activity-in-cortical-networks
#13
Rocco Pulizzi, Gabriele Musumeci, Chris Van den Haute, Sebastiaan Van De Vijver, Veerle Baekelandt, Michele Giugliano
Cell assemblies manipulation by optogenetics is pivotal to advance neuroscience and neuroengineering. In in vivo applications, photostimulation often broadly addresses a population of cells simultaneously, leading to feed-forward and to reverberating responses in recurrent microcircuits. The former arise from direct activation of targets downstream, and are straightforward to interpret. The latter are consequence of feedback connectivity and may reflect a variety of time-scales and complex dynamical properties...
April 21, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27008657/new-perspectives-on-neuroengineering-and-neurotechnologies-nsf-dfg-workshop-report
#14
Chet T Moritz, Patrick Ruther, Sara Goering, Alfred Stett, Tonio Ball, Wolfram Burgard, Eric H Chudler, Rajesh P N Rao
GOAL: To identify and overcome barriers to creating new neurotechnologies capable of restoring both motor and sensory function in individuals with neurological conditions. METHODS: This report builds upon the outcomes of a joint workshop between the US National Science Foundation and the German Research Foundation on New Perspectives in Neuroengineering and Neurotechnology convened in Arlington, VA, USA, November 13-14, 2014. RESULTS: The participants identified key technological challenges for recording and manipulating neural activity, decoding, and interpreting brain data in the presence of plasticity, and early considerations of ethical and social issues pertinent to the adoption of neurotechnologies...
July 2016: IEEE Transactions on Bio-medical Engineering
https://www.readbyqxmd.com/read/26890082/neural-cells-mobile-microplates-for-morphological-control-and-assembly-of-individual-neural-cells-adv-healthcare-mater-4-2016
#15
Shotaro Yoshida, Tetsuhiko Teshima, Kaori Kuribayashi-Shigetomi, Shoji Takeuchi
Individual neural cells on micro-sized plates are morphologically controlled, mobilized, and utilized as building blocks of a neural circuit. On p. 415, S. Takeuchi and co-workers show how the mobile microplate device enables precise positioning of individual neural cell bodies and neurites in a reproducible fashion, which potentially allows neuroengineers to design the geometry of cultured neural circuits (Cover design: Akiko Sato).
February 2016: Advanced Healthcare Materials
https://www.readbyqxmd.com/read/26888191/journal-of-neuroengineering-and-rehabilitation-reviewer-acknowledgement-2015
#16
David J Reinkensmeyer
The editors of Journal of NeuroEngineering and Rehabilitation would like to thank all of our reviewers who have contributed to the journal in volume 12 (2015).
2016: Journal of Neuroengineering and Rehabilitation
https://www.readbyqxmd.com/read/26850705/cell-transplantation-and-neuroengineering-approach-for-spinal-cord-injury-treatment-a-summary-of-current-laboratory-findings-and-review-of-literature
#17
Xin-Yi Lin, Bi-Qin Lai, Xiang Zeng, Ming-Tian Che, Eng-Ang Ling, Wutian Wu, Yuan-Shan Zeng
Spinal cord injury (SCI) can cause severe traumatic injury to the central nervous system (CNS). Current therapeutic effects achieved for SCI in clinical medicine show that there is still a long way to go to reach the desired goal of full or significant functional recovery. In basic medical research, however, cell transplantation, gene therapy, application of cytokines, and biomaterial scaffolds have been widely used and investigated as treatments for SCI. All of these strategies when used separately would help rebuild, to some extent, the neural circuits in the lesion area of the spinal cord...
2016: Cell Transplantation
https://www.readbyqxmd.com/read/26712104/mobile-microplates-for-morphological-control-and-assembly-of-individual-neural-cells
#18
Shotaro Yoshida, Tetsuhiko Teshima, Kaori Kuribayashi-Shigetomi, Shoji Takeuchi
A microfabricated device that enables morphological control and assembly of cultured single neural cells is described. Assembly of morphologically controlled single neural cells allows neuroengineers to design in vitro neural circuits with a single-cell resolution. Compared to conventional cell-patterning techniques, the device allows for the highly precise positioning of neural somas and neurites in a reproducible fashion.
February 18, 2016: Advanced Healthcare Materials
https://www.readbyqxmd.com/read/26504211/behavioral-assessment-of-sensitivity-to-intracortical-microstimulation-of-primate-somatosensory-cortex
#19
Sungshin Kim, Thierri Callier, Gregg A Tabot, Robert A Gaunt, Francesco V Tenore, Sliman J Bensmaia
Intracortical microstimulation (ICMS) is a powerful tool to investigate the functional role of neural circuits and may provide a means to restore sensation for patients for whom peripheral stimulation is not an option. In a series of psychophysical experiments with nonhuman primates, we investigate how stimulation parameters affect behavioral sensitivity to ICMS. Specifically, we deliver ICMS to primary somatosensory cortex through chronically implanted electrode arrays across a wide range of stimulation regimes...
December 8, 2015: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/26231048/republication-of-elevating-the-quality-of-disability-and-rehabilitation-research-mandatory-use-of-the-reporting-guidelines
#20
EDITORIAL
Leighton Chan, Allen W Heinemann, Jason Roberts
Journal of NeuroEngineering and Rehabilitation advocates the complete and transparent reporting of research and methods, and is pleased to be part of an initiative to mandate the use of reporting guidelines. This Editorial is a republication of a previously published Editorial in Archives of Physical Medicine and Rehabilitation ( http://dx.doi.org/10.1016/j.apmr.2013.12.010 ), and is republished here under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs 3.0 License ( http://creativecommons...
2015: Journal of Neuroengineering and Rehabilitation
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